AIDS 바이러스 역전사 및 DNA 중합효소의 활성에 대한 카테킨 유도체의 억제작용

Tao Pei Zhen,Zhang Tian,Zhou Ping,Wang Shu Qin,Cheng Shu Jun,Jiang Jing Yi,Guo Ju Tao,Chen Hong Shan 한국식품과학회 1993 국제녹차심포지엄 Vol.1993 No.1

Anesthetic Management and Outcomes of Endovascular Treatment of Basilar Artery Occlusion: Results From the ATTENTION Registry

Tao Chunrong,Yuan Guangxiong,Xu Pengfei,Wang Hao,Zhou Peiyang,Yi Tingyu,Li Kai,Cui Tao,Gao Jun,Li Rui,Sun Jun,Zhang Chao,Wang Li,Liu Tianlong,Song Jianlong,Yin Yamei,Nguyen Thanh N.,Li Qing,Hu Wei 대한뇌졸중학회 2023 Journal of stroke Vol.25 No.3

Background and Purpose To examine the clinical and safety outcomes after endovascular treatment (EVT) for acute basilar artery occlusion (BAO) with different anesthetic modalities. Methods This was a retrospective analysis using data from the Endovascular Treatment for Acute Basilar Artery Occlusion (ATTENTION) registry. Patients were divided into two groups defined by anesthetic modality performed during EVT: general anesthesia (GA) or non-general anesthesia (non-GA). The association between anesthetic management and clinical outcomes was evaluated in a propensity score matched (PSM) cohort and an inverse probability of treatment weighting (IPTW) cohort to adjust for imbalances between the two groups. Results Our analytic sample included 1,672 patients from 48 centers. The anesthetic modality was GA in 769 (46.0%) and non-GA in 903 (54.0%) patients. In our primary analysis with the PSM-based cohort, non-GA was comparable to GA concerning the primary outcome (adjusted common odds ratio [acOR], 1.01; 95% confidence interval [CI], 0.82 to 1.25; <i>P</i>=0.91). Mortality at 90 days was 38.4% in the GA group and 35.8% in the non-GA group (adjusted risk ratio, 0.95; 95% CI, 0.83 to 1.08; <i>P</i>=0.44). In our secondary analysis with the IPTW-based cohort, the anesthetic modality was significantly associated with the distribution of modified Rankin Scale at 90 days (acOR: 1.45 [95% CI: 1.20 to 1.75]). Conclusion In this nationally-representative observational study, acute ischemic stroke patients due to BAO undergoing EVT without GA had similar clinical and safety outcomes compared with patients treated with GA. These findings provide the basis for large-scale randomized controlled trials to test whether anesthetic management provides meaningful clinical effects for patients undergoing EVT.

Behavior of hybrid CFST with FRP-confined UHPC core under axial compression

Yi Tao,Jin-Ben Gu,Jian-Fei Chen,Peng Feng 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.40 No.1

A fiber-reinforced polymer (FRP)-confined concrete core that provides high strength and ductility under axial compression can act as strength enhancement in a hybrid column. In the present study, ordinary concrete was replaced with ultra-high-performance concrete (UHPC) to form an FRP-confined UHPC core (FCUC). The FCUC was embedded in square concrete-filled steel tube (CFST) columns to form a high-performance hybrid column (SCF-UHPC column for short). The axial compressive behavior of the SCF-UHPC was experimentally investigated using 12 SCF-UHPC columns and two ordinary CFST columns for comparison. The advantages of the SCF-UHPC include excellent axial load-bearing capacity, good ductility, and stable residual load-bearing capacity. The results show that failure of an SCF-UHPC column was caused by FRP rupture of FCUC, which occurred after steel tube buckling that results in the degraded stiffness. It was also shown that the load-displacement behavior of the SCF-UHPC composite column was determined by the UHPC core diameter and the corresponding confinement provided by the outer steel tube and inner FRP jacket. A hardening effect could be achieved when the confinement demand of the UHPC core was satisfied, whereas a plateau effect appeared if the confinement was insufficient. Furthermore, the load-bearing capacity and ductility of the SCF-UHPC columns improved with increased thickness of the steel tube and the FRP.

Active Earth Pressure Against Rigid Retaining Wall Considering Effects of Wall-soil Friction and Inclinations

Yi Tao Zhou 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.12

This paper reports a new method for calculating the active earth pressure acting on inclined rigid retaining wall with inclined backfill, considering wall-soil interface friction angle. Based on Mohr-Coulomb strength theory and Mohr stress circle, new formulae of the active earth pressure and the active rupture angle are derived. The effects of internal friction angle, backfill-surface inclination, wall-back inclination on the active earth pressure and the active rupture angle are investigated. In order to facilitate calculation, special solutions of presented formulae are discussed under various particular conditions. Finally, the calculated results from the presented formula and existing formulae are compared with existing small-scale test results. The comparison shows that the presented method satisfactorily predicts active earth pressure.

Extraskeletal Ewing Sarcomas in Late Adolescence and Adults: A Study of 37 Patients

Tao, Hai-Tao,Hu, Yi,Wang, Jin-Liang,Cheng, Yao,Zhang, Xin,Wang, Huan,Zhang, Su-Jie Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

Background: Extraskeletal Ewing sarcoma (EES)/primitive neuroectodermal tumours (PNET) are rare soft tissue sarcomas. Prognostic factors and optimal therapy are still unconfirmed. Materials and Methods: We performed a retrospective analysis on patients to explore the clinic characteristics and prognostic factors of this rare disease. A total of 37 patients older than 15 years referred to our institute from Jan., 2002 to Jan., 2012 were reviewed. The characteristics, treatment and outcome were collected and analyzed. Results: The median age was 28 years (range 15-65); the median size of primary tumours was 8.2 cm (range 2-19). Sixteen patients (43%) had metastatic disease at the initial presentation. Wide surgical margins were achieved in 14 cases (38%). Anthracycline or platinum-based chemotherapy was performed on 29 patients (74%). Radiotherapy was delivered in 13 (35%). At a median follow-up visit of 24 months (range 2-81), the media event-free survival (EFS) and overall survival (OS) were 15.8 and 30.2 months, respectively. The 3-year EFS and OS rates were 24% and 43%, respectively. Metastases at presentation and wide surgical margins were significantly associated with OS and EFS. Tumour size was significantly associated with OS but not EFS. There were no significant differences between anthracycline and platinum based chemotherapy regarding EFS and OS. Conclusions: EES/PNET is a malignant tumour with high recurrence and frequent distant metastasis. Multimodality therapy featuring wide surgical margins, aggressive chemotherapy and adjuvant local radiotherapy is necessary for this rare disease. Platinum-based chemotherapy can be used as an adjuvant therapy.

An integrated dendrite-free zinc metal electrode for corrosion inhibition in aqueous system

Yi-Fan Hu,Li-Feng Zhou,He Gong,He Jia,Peng Chen,Yi-Song Wang,Li-Ying Liu,Tao Du 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.9

Zinc ion batteries have gotten increasing attention as a potential candidate for lithium-ion batteries, due totheir high specific capacity (820 mAh·g1), energy density, and safety. Inevitably, dendrite and corrosion create sometrouble for this system. Herein, an integrated Zn electrode coated by Zn-Al metal oxides prepared by a simple spincoatingmethod was utilized to increase the rechargeability for aqueous zinc ion batteries. By coating the Zn anodewith an artificial electrolyte interface, the wettability of Zn anodes was improved and impedance was reduced. Thecoating suppressed not only the appearance of dendrite but also the formation of corrosion products. The symmetricalcells with coating have a low overpotential (43mV) and an excellent life span. Meanwhile, the applied full batteriesexhibit an improved capacity retention rate (86.67% after 120 cycles), great rate performance and low apparent activationenergy (24.6 KJ·mol1). The simple production methods and superior corrosion suppression effects provide newideas for the anode protection of aqueous system batteries.

Clinical Efficacy and Prognosis Factors for Advanced Hepatoblastoma in Children: A 6-year Retrospective Study

Zhang, Yi,Zhang, Wei-Ling,Huang, Dong-Sheng,Hong, Liang,Wang, Yi-Zhuo,Zhu, Xia,Hu, Hui-Min,Zhang, Pin-Wei,Yi, You,Han, Tao Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

Objective: This study aimed to investigate the effect of multimodality treatment of advanced paediatric hepatoblastoma (HB) and the factors affecting prognosis. Methods: A total of 35 children underwent multimodality treatments consisting of chemotherapy, surgery, interventional therapy, and autologous peripheral blood stem cell transplantation. The patients were followed up every month. Results: Serum AFP levels in 33 out of 35 patients in this study were significantly increased (P = 0.0002). According to the statistical scatter plot, the values of serum AFP on the 25th, 50th, and 75th percentages were 1,210, 1,210 and 28,318 ng/dl, respectively. Of the 35 cases, 21 were stage IV. 18 cases were treated with systemic chemotherapy before surgery, and 3 cases with locally interventional chemotherapy before surgery. Statistical analysis showed that the preferred interventional treatment affected prognosis, and that there was a statistically significant difference (P = 0.024). Some 33 patients completed the follow-up, of which 17 were in complete remission (CR), 5 were in partial remission (PR), 1 became disease progressive (DP), and 10 died. The remission and overall survival rates were 66.7% (22/33) and 69.7% (23/33), respectively. Patients with the mixed HB phenotypes had worse prognoses than the epithelial phenotype (P < 0.001), and patients in stage IV had a lower survival rate than those in stage III (P < 0.001). Conclusion: Multimodality treatment can effectively improve remission rate and prolong the survival of children with advanced HB. In addition, alpha-fetoprotein (AFP), a tumor marker of liver malignant tumors, HB pathological classification, and staging are highly useful in predicting prognosis.

Kinetic study on carbonation of crude Li_2CO_3 with CO_2-water solutions in a slurry bubble column reactor

Wen-Tao Yi,Chun-Yan Yan,Pei-Hua Ma 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.3

Investigations were conducted to purify crude Li_2CO_3 via direct carbonation with CO_2-water solutions at atmospheric pressure. The experiments were carried out in a slurry bubble column reactor with 0.05 m inner diameter and 1.0 m height. Parameters that may affect the dissolution of Li_2CO-3 in the CO_2-water solutions such as CO-2-bubble perforation diameter, CO_2 partial pressure, CO_2 gas flow rate, Li-2CO-3 particle size, solid concentration in the slurry,reaction temperature, slurry height in the column and so on were investigated. It was found that the increases of CO_2partial pressure, and CO_2 flow rate were favorable to the dissolution of Li_2CO_3, which had the opposite effects with Li_2CO_3 particle size, solid concentration, slurry height in the column and temperature. On the other hand, in order to get insight into the mechanism of the refining process, reaction kinetics was studied. The results showed that the kinetics of the carbonation process can be properly represented by 1−3(1−X)^(2/3)+2(1−X)=kt+b, and the rate-determining step of this process under the conditions studied was product layer diffusion. Finally, the apparent activation energy of the carbonation reaction was obtained by calculation. This study will provide theoretical basis for the reactor design and the optimization of the process operation.

Modeling for a Live Plant Root: Nitrogen Reduction and Treatment Performance

( Qi Tao Yi ),( Jin Woo Lee ),( Young Chul Kim ) 한국물환경학회 ( 구 한국수질보전학회 ) 2007 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2007 No.-

One-Dimensional Transient Wave Propagation in a Dry Overlying Saturated Ground

Jiang Tao Yi,Lei Zhang,Fei Jian Ye,Siang Huat Goh 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.10

While the propagation of stress wave generated by dynamic compaction in dry or saturated granular soil has received much coverage in the research literature, attention to situations with dry soil overlying saturated soil, or mixed-phase ground, is limited. In such cases, the compressional waves have to propagate from a dry layer above the groundwater table to saturated soil below the groundwater table. In this paper, the transient wave propagation characteristics in a mixed-phase ground with an idealized interface between the dry and saturated layer is studied. As the time domain solutions for such problems are often unavailable using analytical methods, a numerical approach based on a dual-phase coupled finite element method implemented on a commercial software platform is adopted. The wave behaviour across the interface is studied and the energy transmission and reflection mechanism from dry to saturated layer is examined. The amplitude, speed and attenuation of the compressional waves and their dependencies on the soil permeability, skeleton stiffness and load duration are quantitatively evaluated via a comprehensive parametric study. As a precursor to the numerical investigation of wave propagation in a mixed-phase ground due to dynamic compaction, the results presented in this study are likely to help in providing a better understanding of the ground improvement effect of dynamic compaction in soil involving a groundwater table.