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Xiaofeng Jiang,De Chen,Guangyang Xiang,Yezeng Wang,Lei Zhang,Xuewei Yang,Liangqi Cao,Heping Peng,Ping Xue 한국분자세포생물학회 2012 Molecules and cells Vol.33 No.6
MicroRNAs (miRNAs) are regulatory small non-coding RNAs that can regulate gene expression by binding to gene elements, such as the gene promotor 5UTR, mainly in the 3UTR of mRNA. One miRNA targets many mRNAs, which can be regulated by many miRNAs, leading to a complex metabolic network. In our study, we found that the expression level of miR-590-5p is higher in the human hepatocellular carcinoma cell line HepG2 than in the normal hepatocellular cell line L02. Downregulation of miR-590-5p inhibited proliferation and invasion of hepatocellular carcinoma cells (HCCs). We also showed that expression of TGF-beta RII, which has been regarded as a regulator of tumor proliferation, invasion, and migration in hepatocellular carcinoma, is regulated by miRNA-590-5p. In addition, miR-590-5p downregulated the expression of TGF- beta RII by targeting the 3UTR of mRNA. We also found that downregulation of miR-590-5p was associated with an elevation of TGF-beta RII and inhibition of proliferation and invasion in HepG2 cells. Furthermore, overex-pression of miR-590-5p was associated with upregulation of TGF-beta RII and could promote proliferation and invasion in L02 cells. In conclusion, we determined that TGF-beta RII is a novel target of miRNA-590-5p. Thus, the role of TGF-beta RII in regulating proliferation and invasion of human HCCs is controlled by miR-590-5p. In other words, miR-590-5p promotes proliferation and invasion in human HCCs by directly targeting TGF-beta RII.
Hydrothermal Synthesis of Ni-MOF Vulcanized Derivatives for High-Performance Supercapacitors
Shuwen Gao,Yanwei Sui,Fuxiang Wei,Jiqiu Qi,Qingkun Meng,Yaojian Ren,Yezeng He 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.3
A series of nickel sulfides derived from the hexagonal Ni-MOF are vulcanized through adjusting the hydrothermal time and the thiourea concentration. Among all the obtained nickel sulfides, one sample Ni-S2-3, which inherits the Ni-MOF's morphology, shows the best electrochemical performance with a remarkable specific capacitance of 1128 Fg -1 at 1 Ag -1, a rate capacitance of 50% and a long cycle life of 74% retention after 5000 cycles. Furthermore, the asymmetrical supercapacitors (SCs) based on Ni-S2-3//AC exhibit a good supercapacitive performance with a maximum power density of 16.3 Wh kg -1 at a power density of 800 Wkg -1. All these results indicate that vulcanizing Ni-MOF is an effective way to fabricate a superior electrode material with excellent electrochemical performance for SCs.
An Ye,Jiqiu Qi,Yanwei Sui,Fei Yang,Fuxiang Wei,Yezeng He,Qingkun Meng,Zhi Sun 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.7
A solid-state energy storage device has been fabricated using FeCo-selenide nanosheet arrays as positive electrode and Fe2O3 nanorod as negative electrode. As an electrode material, the ternary FeCo-selenide nanosheet arrays supported by Ni foam show a highest specific capacitance of 978 F/g (specific capacity of 163 mAh/g) at 1 A/g and a superior cycle behavior of 81.2% are obtained after 5000 cycles at current density of 4 A/g. The asymmetric supercapacitor achieves the maximum energy density of 34.6Wh/kg at the power density of 759.6 W/kg. Furthermore, the superior cycling stability with 83% retention of initial capacitance after 5000 cycles further verify the practical applications of FeCo-selenide//Fe2O3 asymmetric supercapacitor. Meanwhile, the LED bulb and the light board of "CUMT" are lighted by connecting several capacitors to form a series circuit.
Man Zhang,Yanwei Sui,Xiaofang Yuan,Jiqiu Qi,Fuxiang Wei,Qingkun Meng,Yezeng He,Yaojian Ren,Zhi Sun,Jinlong Liu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.3
A nanoflower structure of Zn0.76Co0.24S directly grown on carbon fiber papers (CFP) was successfully designed by a mild two-step hydrothermal method. Benefiting from their fascinating structural features, Zn0.76Co0.24S/CFP electrode exhibits a maximum specific capacitance of 300 F g -1 at current density of 1 A g -1 and 84% capacitance retention after 5,000 cycles at current density of 5 Ag -1. Subsequently, Zn0.76Co0.24S/CFP//AC all-solid-state asymmetric supercapacitor (ASC) device is assembled and able to illuminate the red LEDs. ASC devices deliver a maximum energy density of 9.59 Wh kg -1 at a power density of 750 W kg -1. Therefore, this impressive result demonstrates that the nanoflower Zn0.76Co0.24S have promising applications in the development of high-performance supercapacitors.
Yanwei Sui,Dongling Zhang,Yongpeng Han,Zhi Sun,Jiqiu Qi,Fuxiang Wei,Yezeng He,Qingkun Meng 대한금속·재료학회 2018 ELECTRONIC MATERIALS LETTERS Vol.14 No.5
This work successfully demonstrates various temperature carbonization of iron based metal organic framework to deriveelectrode materials for supercapacitors. Furthermore, impacts of calcined temperatures on the nature of as-prepared productsare reported, and samples obtained at 300, 400, 500, 600 and 700 °C were investigated respectively. The products revealsexcellent electrochemical performance. Carbonized at 600 °C, the composite materials display the highest specific capacitanceof 972 F/g at a current density of 1 A/g. Carbonized at 500 °C, the capacitance retention of materials reach up to 93%. The high specific capacitance and excellent cyclic stability of the developed materials would exhibit nice prospect for thepractical utilization of electrode materials.
One-Step Hydrothermal Synthesis of CoNi2S4 for Hybrid Supercapacitor Electrodes
Peng Liu,Yanwei Sui,Fuxiang Wei,Jiqiu Qi,Qingkun Meng,Yaojian Ren,Yezeng He 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.7
In this study, a simple one-step hydrothermal method was developed to prepare a novel hierarchical CoNi2S4 nanostructure similar to rambutan fruit. The surface microstructural study clearly visualized that the rambutan-like CoNi2S4 consists of nanorods grown directly on the surface of spherical core structures. The close attachment of the nanorods to the spheres increased the active areas of the electrode, which facilitates efficient charge transport from the nanorods to the spherical core structure. CoNi2S4 with a rambutan-like hierarchical structure showed an excellent specific capacitance of 944 F g -1 at 1 A g -1, considerable rate capacitance (75.6% retention at 10 Ag -1) and excellent cycling life (91.1% retention after 5000 circulations) in the three-electrode system. Besides, the assembled hybrid supercapacitor based on CoNi2S4 and reduced graphene oxide exhibited a high specific energy density of 23.58 Wh kg -1 at the power density of 800 W kg -1.
Yanwei Sui,Man Zhang,Haihua Hu,Yuanming Zhang,Jiqiu Qi,Fuxiang Wei,Qingkun Meng,Yezeng He,Yaojian Ren,Zhi Sun 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.12
The interconnected three-dimensional Ni–Co–S nanosheets were successfully deposited on ZnO nanorods by a one-step potentiostatic electrodeposition. The Ni–Co–S nanosheets provide a large electrode/electrolyte interfacial area which has adequate electroactive sites for redox reactions. Electrochemical characterization of the ZnO@Ni–Co–S core–shell nanorods presents high specifc capacitance (1302.5 F/g and 1085 F/g at a current density of 1 A/g and 20 A/g), excellent rate capabilities (83.3% retention at 20 A/g) and great cycling stability (65% retention after 5000 cycles at a current density of 30 A/g). The outstanding electrochemical performance of the as-prepared electrode material also can be ascribed to these reasons that the special structure improved electrical conductivity and allowed the fast diffusion of electrolyte ions.