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      • Propofol이 일측폐환기 마취시 동맥혈 산소화 및 기도압에 미치는 효과

        전영훈,임동건 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.1

        목적 : 폐 수술을 위한 전신마취시 일측폐환기는 저산소혈증 및 기도압 증가를 유발시킬 수 있다. 본 연구는 일측폐환기시 동맥혈 산소분압 및 기도압에 대한 propofol과 enflurane의 효과를 비교 평가 하고자 한다. 대상 및 방법 : 측와위, 일측폐환기로 수술 예정된 환자 30명을 임의로 propofol군 및 enflurane군으로 나누었다. 심박수, 평균동맥압, 산소포화도를 측정후 thiopental로 마취유도 후 enflurane(2Vol%)-O_2(2.5㎖/min)-N_2O(1.5㎖/min)로 마취유지하였다. Enflurane 군은 일측폐환기 시에도 이를 유지하였으며, propofol 군은 일측폐환기 35분후 enflurane 흡입을 중지하고 propofol을 정주하였다. 일측폐환기 후 5분 간격으로 75분간 심박수, 평균동맥압, 최대흡기압, 휴지기압, 평균호흡기압을 측정하였고, 일측폐환기 시작전, 환기후 35분, 65분 후 동맥혈 가스분석을 시행하였다. 자료의 통계분석은 t-test, paired t-test 및 repeated measures of ANOVA를 이용하여 p값이 0.05이하일 때 유의한 것으로 판별하였다. 결과 : Propofol 군에서 일측폐환기 65분후 측정한 동맥혈 산소분압의 변화율이 35분후 측정치에 비하여 유의한 증가를 보였다. 최대흡기압과 평균기도압은 propofol 정주 20분후(일측폐환기 55분 후)에 일측폐환기 35분 후 측정치에 비하여 유의하게 감소하였다. 결론 : 이상의 실험으로 일측폐환기를 이용한 전신마취시 propofol은 동맥혈 산소화를 개선시키고 기도압을 감소시키며 부하용량의 점진적 주사시 급격한 혈역학적 변화를 나타내지 않는다고 하겠다. Hypoxemia and high airway pressure would be occured during one lung ventilation(OLV). The aim of the present study was to evaluate the effect of enflurane and propofol on oxygenation and airway pressure during OLV. 30 patients undergoing thoracic surgery were assigned randomly to two goups. After heart rate(HR), mean arterial pressure(MAP) and oxygen saturation(SpO_2) were checked, anesthesia was induced with thiopental sodium and was maintained with enflurane(2 vol%)-O_2-(2.5 ℓ/min)-N_2O(1.5 ℓ/min). Enflurane group was maintained with enflurane during OLV and propofol group was maintained with propofol from 35 min after OLV. After OLV, for 75 min at interval of 5 min, HR, MAP, peak inspiratory pressure (PIP), pause pressure(PP) and mean airway pressure(PM) were checked and aterial blood gas analysis was done before OLV, at 35min, 65min after OLV. The results were as follows In propofol-group after OLV, PaO_2 at 65min was increased significantly compared to PaO_2 at 35min and PIP and PM at 65 min were improved compared to PIP and PM at 35 min. In conclusion, these results suggest propofol may improve oxygenation and reduce airway pressure OLV.

      • The Studies on In Vivo Embryo Production using Sex-Sorted Sperm in Hanwoo

        Yeoung-Gyu Ko,Sung Woo Kim,Dong-Kyo Kim,Nam-Tae Kim,Chan-Lan Kim,Ik-Soo Jeon,Min-Su Kim 한국수정란이식학회 2018 한국수정란이식학회 학술대회 Vol.2018 No.11

        The present study was to assess the in vivo embryo production efficiency using the semen separated according to sex during superovulation in Hanwoo. Seventy Hanwoo donor cows were flushed on day 7 of estrus cycle with same FSH and artificial insemination by the same technicians. Embryos were recovered on 7 days after the third insemination by flushing the uterus with embryo collection medium. KPN semen straws used artificial insemination contained 20 million sperm (total number 60 million per donor). Sex-sorted semen straws contained 4 million sperm (total number 12 million per donor). The results obtained were as follows: No differences were observed in the efficiency of superovulation rates on KPN semen 87%, and sexed semen 100%, respectively. The mean numbers of total embryos are each 12.58 ± 8.31 and 13.25 ± 7.86. The mean numbers of transferable embryos, sexed semen were significantly lower than KPN semen (3.75 ± 1.98 vs. 8.23 ± 6.07, P<0.05). The rates of unfertilized embryos from superovulation using sexed semen were significantly higher than KPN semen (50% vs. 15%, P<0.05). The rate of degenerated 2-cell embryos from sexed and KPN semen was 60.87% and 11.11%, respectively (p<0.05). In conclusion, these results indicate that superovulation using sexed semen was useful, but efficient embryo production was important to reducing the damage caused by the Flowcytometer-based sperm sorting procedure.

      • KCI등재

        Effect of Feed Restriction in Modeling of Dietary Obesity

        Yeoung Mi Cho,Sunhee Shin,Dongsun Park,Jeong Hee Jeon,Min-Jung Jang,Jwa Jin Kim,Jae Wook Kim,Hyeong-Jin Ji,Chang Hwan Kim,Seongjin Baek,Seok-Yeon Hwang,Gonhyung Kim,Yun-Bae Kim 한국실험동물학회 2007 Laboratory Animal Research Vol.23 No.4

        Ad libitum feeding of normal diet to rats usually leads to overweight, showing higher body-mass index than 25, while the supplementation of high (20-40%) content of lard or beef tallow in the diet to make a high-fat diet (HFD)-induced obesity rather decreases body weights partially due to decrease in feed intake of HFD or occurrence of diarrhea. In our study, for modeling dietary obesity, rats were subjected to feed restriction by 20 and 40% with normal diet or HFD supplemented with 25% of lard for 6 weeks. Ad libitum (100%) feeding of HFD decreased body weight gain and body fat in rats, resulting from a lower feed intake and transient diarrhea, compared to that of animals fed normal diet. In comparison with ad libitum-feeding groups, HFD restricted to 60 and 80% resulted in higher body weight gain and body fat compared with the normal diet with corresponding restriction to 60% or 80%. The changes in body and fat weights exhibited a good relationship with blood lipids profiles and leptin level in feed restricted groups. In addition, body fat and lipid profiles were confirmed to be parallel with the lipid accumulation in the liver and blood parameters associated with liver function. Based on the results, it is suggested that an appropriate degree (80%) of dietary restriction could be a candidate of modeling HFD-induced obesity for the screening of antiobesity substances.

      • 光波長이 오이(Cucumis sativus L.) 플러그苗의 生長에 미치는 影響

        용영록,전지영,황세진,김일섭,정천순 강릉대학교 동해안지역연구소 2000 東海岸硏究 Vol.11 No.1

        This research was carried to find out the optimum artificial light condition for plug seedling production of high quality cucumber through investigating growth response of the seedling by both light wave length and treatment period. The treatment with blue and red fluorescent lamp increased the fresh weight involving hypocotyl and root and controlled the elongation of hypocotyl, compared with other treatments. The 30-day-old seedling treatment with blue and red light for 12 hours showed that vegetative growth including root, stem and leaves was better than that of seedling treated with other lamps. Seedling under blue and red light for 12 hours grew 60.0mm and 0.55g in length and weight of hypocotyl. respectively, Hypocotyl length and weight were 44.9mm and 0.62g when seedling was grown under above light condition for 6 hours. Total chlorophyll contents of hypocotyl were highest in the light mixing treatment, and this accelerated greening. Morphological characteristics by investigating cross and longitudinal section of 30-day-old cucumber seedling treated with the mixing fluorescent lamps indicated that epidrmis tissues were usually single layer and thicker, resulting in small, compact and non-intercellular spaces of cells. On the other hand, epidermis tissues of the control composed of large, longer and round cells and cortex tissues showed large intercellular spaces between cells. Longitudinal section of photo-treated hypocotyl showed that there were more shorter cells and non-intercellular spaces of cells than untreated tissues. As a result, blue and red light mixing treatment controled the cell elongation of seedling hypocotyl, resulting in shortening hypocotyl of cucumber seedling.

      • 종자 Priming 반응 Indicator로서 호흡부산물 특성에 관한 연구

        용영록,전지영 강릉대학교 동해안지역연구소 2000 東海岸硏究 Vol.11 No.1

        This study was conducted to investigate effects of salt priming on germination of muskmelon seeds and to find out the optimum condition for priming by comparing respiration by-products(carbon dioxide) produced during treatment. Germination rate was 96% and T50 was reduced to 1.9 days in seeds with KNO3 100mM and air supply, compared 84% and 3.7 days of the rate and T50 in nontreated seeds, respectively. Adding KNO3 200mM with oxygen, nitrogen and air supply to priming solutions made priming more effective at improving germination responses. However in more than 4 days treatment with nitrogen. priming effects seriously decreased. When KNO3 300mM applied with oxygen and air, germination rate was improved. The more concentrations of KNO3 applied to primling solution, the more CO2 produced, resulted in inducing maximum CO2 production in KNO3 300mM applications. There were not found significant correlations between respiration by-products and germination rate.

      • 송전계통의 전기품질 측정 시스템에 관한 연구

        김영노(Yeoung Noh Kim),신봉일(Bong Il Shin),이희철(Hee Chul Lee),곽노홍(No Hong Kwak),전영수(Young soo Jeon),박상호(Sang Ho Park),이일무(Il Moo Lee) 전력전자학회 2006 전력전자학술대회 논문집 Vol.- No.-

        The additional matters appear to be considered in several aspects for building up power-quality measuring system of transmission system(high voltage system) compared to distribution system(middle or low voltage system). Like in distribution system, input signals are also received from PT and CT source of voltage and current respectively in transmission system and applied in accordance with a certain rate. In this case, very big error rate can be occurred according to the specification of the measuring system as the applying rate is bigger than in distribution system beyond comparison. In addition, when the abnormal signal occurred such as sag/swell, interruption, transient etc. power quality of other sites linked to the system also should be checked to find the accurate cause of the abnormal power-quality signals from the corresponding. site. Accordingly, the accurate diagnosis on the condition of power quality for the system depends on the way how the synchronization system is brought along for each site. This paper will suggest the solution for the most effective system building focused on how to solve the problem of the error rate and synchronization described in the above when building up the measuring system of power quality for transmission system.

      • KCI등재
      • 송전계통의 전기품질 측정 시스템에 관한 연구

        김영노(Yeoung Noh Kim),신봉일(Bong Il Shin),이희철(Hee Chul Lee),곽노홍(No Hong Kwak),전영수(Young soo Jeon),박상호(Sang Ho Park),이일무(Il Moo Lee) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.7

        The additional matters appear to be considered in several aspects for building up power-quality measuring system of transmission system(high voltage system) compared to distribution system(middle or low voltage system). Like in distribution system, input signals are also received from PT and CT source of voltage and current respectively in transmission system and applied in accordance with a certain rate. In this case, very big error rate can be occurred according to the specification of the measuring system as the applying rate is bigger than in distribution system beyond comparison. In addition, when the abnormal signal occurred such as sag/swell, interruption, transient etc., power quality of other sites linked to the system also should be checked to find the accurate cause of the abnormal power-quality signals from the corresponding site. Accordingly, the accurate diagnosis on the condition of power quality for the system depends on the way how the synchronization system is brought along for each site. This paper will suggest the solution for the most effective system building focused on how to solve the problem of the error rate and synchronization described in the above when building up the measuring system of power quality for transmission system.

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