Enhanced bipolar fatigue resistance in CaZrO3-modified (K,Na)NbO3 lead-free piezoceramics

Yao, Fang-Zhou,Patterson, Eric A.,Wang, Ke,Jo, Wook,Rö,del, Jü,rgen,Li, Jing-Feng American Institute of Physics 2014 APPLIED PHYSICS LETTERS Vol.104 No.24

Establishing a Nomogram for Stage IA-IIB Cervical Cancer Patients after Complete Resection

Zhou, Hang,Li, Xiong,Zhang, Yuan,Jia, Yao,Hu, Ting,Yang, Ru,Huang, Ke-Cheng,Chen, Zhi-Lan,Wang, Shao-Shuai,Tang, Fang-Xu,Zhou, Jin,Chen, Yi-Le,Wu, Li,Han, Xiao-Bing,Lin, Zhong-Qiu,Lu, Xiao-Mei,Xing, H Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

Background: This study aimed to establish a nomogram by combining clinicopathologic factors with overall survival of stage IA-IIB cervical cancer patients after complete resection with pelvic lymphadenectomy. Materials and Methods: This nomogram was based on a retrospective study on 1,563 stage IA-IIB cervical cancer patients who underwent complete resection and lymphadenectomy from 2002 to 2008. The nomogram was constructed based on multivariate analysis using Cox proportional hazard regression. The accuracy and discriminative ability of the nomogram were measured by concordance index (C-index) and calibration curve. Results: Multivariate analysis identified lymph node metastasis (LNM), lymph-vascular space invasion (LVSI), stromal invasion, parametrial invasion, tumor diameter and histology as independent prognostic factors associated with cervical cancer survival. These factors were selected for construction of the nomogram. The C-index of the nomogram was 0.71 (95% CI, 0.65 to 0.77), and calibration of the nomogram showed good agreement between the 5-year predicted survival and the actual observation. Conclusions: We developed a nomogram predicting 5-year overall survival of surgically treated stage IA-IIB cervical cancer patients. More comprehensive information that is provided by this nomogram could provide further insight into personalized therapy selection.

Differential settlement and soil dynamic stress of a culvert-embankment transition zone due to an adjacent shield tunnel construction

Yao Shan,Shunhua Zhou,Yao Shu 대한토목학회 2018 KSCE Journal of Civil Engineering Vol.22 No.7

The effects of shield tunnel construction on the differential settlement and the distribution of soil dynamic stress of an adjacentculvert-embankment transition zone are investigated. A construction project of shield tunnels in Hangzhou (China) beneath anexisting railroad culvert-embankment transition zone is employed as a case study. Firstly, the shield tunneling activities in the vicinityof a culvert-embankment transition zone are simulated by a three-dimensional (3D) Finite Element Analysis (FEA) method. Thedifferential settlement of the transition zone is calculated to evaluate the influence of the shield tunneling on the safety of the passingtrain. Secondly, a plane strain model is employed to investigate the discipline of the soil dynamic stress in transition zones, which isinduced by the passing train and the shield tunnel beneath the railroad. Results indicate that the reinforcement treatment of thefoundation is required since the embankment differential settlement is significantly affected by the shield tunneling. Finally, arecommended treatment is introduced according to the property of the surrounding soil. Numerical simulation reveals that thistreatment is appropriate for reducing the differential settlement and soil dynamic stress of the transition zone.

Cloning and Characterization of Filamentous Fungal S-Nitrosoglutathione Reductase from Aspergillus nidulans

( Yao Zhou ),( Shengmin Zhou ),( Haijun Yu ),( Jingyi Li ),( Yang Xia ),( Baoyi Li ),( Xiaoli Wang ),( Ping Wang ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.5

S-Nitrosoglutathione reductase (GSNOR) metabolizes S-nitrosoglutathione (GSNO) and has been shown to play important roles in regulating cellular signaling and formulating host defense by modulating intracellular nitric oxide levels. The enzyme has been found in bacterial, yeast, mushroom, plant, and mammalian cells. However, to date, there is still no evidence of its occurrence in filamentous fungi. In this study, we cloned and investigated a GSNOR-like enzyme from the filamentous fungus Aspergillus nidulans. The enzyme occurred in native form as a homodimer and exhibited low thermal stability. GSNO was an ideal substrate for the enzyme. The apparent Km and kcat values were 0.55 mM and 34,100 min-1, respectively. Substrate binding sites and catalytic center amino acid residues based on those from known GSNORs were conserved in this enzyme, and the corresponding roles were verified using site-directed mutagenesis. Therefore, we demonstrated the presence of GSNOR in a filamentous fungus for the first time.

Comparison of the effect of lithium bentonite and sodium bentonite on the engineering properties of bentonite-cement-sodium silicate grout

Zhou, Yao,Wang, Gui H.,Chang, Yong H. Techno-Press 2020 Advances in concrete construction Vol.9 No.3

This paper focuses on the engineering properties of Bentonite-Cement-Sodium silicate (BCS) grout, which was prepared by partially replacing the ordinary Portland cement in Cement-Sodium silicate grout with lithium bentonite (Li-bent) and sodium bentonite (Na-bent), respectively. The effect of different Water-to-Solid ratio (W/S) and various replacement percentages of bentonite on the apparent viscosity, bleeding, setting time, and early compressive strength of BCS grout were investigated. The XRD method was used to detect its hydration products. The results showed that both bentonites played a positive role in the stability of BCS grout, increased its apparent viscosity. Na-bent prolonged the setting time of BCS, while 5% of Li-bent shortened the setting time of BCS. The XRD analysis indicated that the hydration products between the mixture containing Na-bent and Li-bent did not differ much. Using bentonite as supplementary cementitious material (SCM) to replace partial cement is a promising way to cut down on carbon dioxide emissions and to produce low-cost, eco-friendly, non-toxic, and water-resistant grout. In addition, Li-bent was superior to Na-bent in improving the strength and the thickening of BCS grouts.

Effect of poling temperature on piezoelectricity of CaZrO₃-modified (K, Na)NbO₃-based lead-free ceramics

Yao, Fang-Zhou,Wang, Ke,Jo, Wook,Lee, Jae-Shin,Li, Jing-Feng American Institute of Physics 2014 JOURNAL OF APPLIED PHYSICS - Vol.116 No.11

HOCl Oxidation-modified CT26 Cell Vaccine Inhibits Colon Tumor Growth in a Mouse Model

Zhou, Rui,Huang, Wen-Jun,Ma, Cong,Zhou, Yan,Yao, Yu-Qin,Wang, Yu-Xi,Gou, Lan-Tu,Yi, Chen,Yang, Jin-Liang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

Despite progress in elucidating mechanisms associated with colorectal cancer and improvement of treatment methods, it remains a frequent cause of death worldwide. New and more effective therapies are therefore urgently needed. Recent studies have shown that immunogenicity of whole ovarian tumor cells and subsequent T cell response were potentiated by oxidation modification with hypochlorous acid (HOCl) in vitro and ex vivo. These results prompted us to investigate the protective antitumor response with an HOCl treated CT26 colorectal cancer cell vaccine in an in vivo mouse model. Administration of HOCl modified vaccine triggered robust antitumor immunity to autologous tumor cells in mice and prolonged survival period significantly. In addition, increased necrosis and apoptosis were found in tumor tissue from the oxidation group. Interestingly, ELISPOT assays showed that specific T cell responses were not elicited in response to the immunizing cellular antigen, in contrast to raising sera antibody titer and antibody binding activity shown by ELISA assay and flow cytometry. Further evaluation of the mechanisms underlying HOCl modified vaccine mediated humoral immunity highlighted the role of antibody-dependent cell-mediated cytotoxicity. These results combined with previous studies suggest that HOCl oxidation modified whole cell vaccine has wide applicability as a cancer vaccine because it can target both T cell- and B cell-specific responses. It may thus represent a promising approach for the immunotherapy of colorectal cancer.

The Funding system for Shanghai Metro And The Practical Experiences of Utilizing Foreign Funds

Zhou Yao Dong 대한교통학회 1998 대한교통학회 기타자료 Vol.1998 No.-

Metro, as a kind of city rail transit, is a modem city passenger transit system with mass transportation and independent special rails. It has become a backbone of the traffic in the metropolis and an important modern symbol of a city. A modem traffic system is indispensable for Shanghai to be an international metropolis of finance, trade and economy. At present, Shanghai metro line No. 1 and its extension have been put into operation, metro line No.2 will be put into trial operation by the end of 1999, the Pearl Line, an elevated rail transit system is under construction and other lines will be constructed later according to the plan. But the funding of the city rail transit construction (both metro and light rail) is a big difficult problem to the infrastructure construction of the metropolises either at home or abroad, which is also a problem to restrict the development of the city rail transit of Shanghai. We have learned from the internal and external experiences of the rail transit construction that it is an important means to deal with the funds of the city rail transit construction to actively utilize foreign funds. It makes up the shortage of the internal funds on the one hand, the external advanced science and technology and the management experiences can be introduced on the other hand. In order to discuss and study conveniently with you together the new problems appearing in the metro construction and to open up a new train of thought, this article will give out a certain analysis and description to the funding method in the metro construction of Shanghai and the characteristics of utilizing foreign funds in the rail transit construction as well as the problems which we are faced with.

Basic Properties and Engineering Application of Bentonite-Cement-Water Glass Grouting

Yao Zhou,Gui He Wang,Yu Fei Yuan 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.9

The cement manufacturing process causes environmental problems such as carbon dioxide emissions. Bentonite-cement-water glass grouting (BCG) is a grout with low environmental impact, designed to reduce the use of cement. The significance of this study is to explore the fundamental properties of BCGs with the bentonite contents of up to 50%, and the antiwash-out and permeability characteristics of BCG in comparison with cement-water glass grout (CG). The effects of water-to-solid ratios (W/S), bentonite content, water glass content and the volume ratio of bentonite-cement slurry to water glass slurry (Va: Vb) on the fundamental properties of BCGs were tested in the laboratory. The results show that the BCGs have excellent characteristics of high viscosity, low bleeding, short and controllable setting time, and high early strength. The BCGs have been applied to the pre-grouting of the water-rich sandy pebble stratum in the Wangfujing North Station section of Beijing Metro Line 8 and achieved better water sealing and reinforcement effects than CG.

Incorporating CsPbBr3 Nanocrystals into Porous AlO(OH) Matrices to Improve their Stability in Backlit Displays

Jiangcong Zhou,Yiqing Lai,Na Lin,Xiaotian Huang,Yu Chen,Yao Yao,Bo Wang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.15 No.01

Currently, the poor stability of inorganic perovskite CsPbX3 (X = Cl, Br, I) nanocrystals restricts their practical application in optoelectronic devices. Therefore, improving the stability of this material remains an urgent task for most researchers. In this study, incorporation of CsPbBr3 nanocrystals into porous AlO(OH) matrices through simple in situ synthesis was demonstrated to be an efficient approach for improving the nanocrystal stability. X-ray diffraction (XRD) revealed that the as-obtained product was composed of cubic CsPbBr3 nanocrystals and orthorhombic AlO(OH) compounds. In addition, transmission electron microscopy (TEM) revealed that the CsPbBr3 nanocrystals were successfully encapsulated by AlO(OH) matrices. The Brunauer–Emmett–Teller (BET) specific surface area was 234.96 m2 g -1 for AlO(OH) and 60.08 m2 g -1 for the CsPbBr3@AlO(OH) composites. The decrease in surface area could be attributed to the filling of the AlO(OH) pores by the CsPbBr3 nanocrystals. Further, the as-prepared composites showed red-shifted emission at 522 nm and a larger full width at half-maximum (FWHM) as 26 nm, compared with those of the CsPbBr3 nanocrystals with the emission at 517 nm and FWHM as 17 nm. More importantly, the emission intensity preserved 67% of the original value after a storage time of 120 h, but bare CsPbBr3 nanocrystals rapidly degraded within only 1 h in the polar ethanol solution. Finally, a light-emitting diode (LED) device was fabricated by coating the CsPbBr3@AlO(OH) composites and red commercial K2SiF6:Mn4+ phosphors on the surface of a blue InGaN chip, covering 96% of National Television Standards Committee. The results indicate that the obtained composites could be promising luminescent materials for backlit displays.