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( Zhang Yankui ),( Xu Haiyun ),( Ba Bin ),( Zong Rong ),( Wang Daming ),( Li Xiangzhi ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.5
The existing direct position determinations(DPD) for coherently distributed(CD) sources are mostly applicable for uniform linear array(ULA), which result in a low degree of freedom(DOF), and it is difficult for them to realize the effective positioning in underdetermined condition. In this paper, a novel DPD algorithm for coherently distributed sources based on compressed sensing with a moving nested array is present. In this algorithm, the nested array is introduced to DPD firstly, and a positioning model of signal moving station based on nested array is constructed. Owing to the features of coherently distributed sources, the cost function of compressed sensing is established based on vectorization. For the sake of convenience, unconstrained transformation and convex transformation of cost functions are carried out. Finally, the position coordinates of the distribution source signals are obtained according to the theory of optimization. At the same time, the complexity is analyzed, and the simulation results show that, in comparison with two-step positioning algorithms and subspace-based algorithms, the proposed algorithm effectively solves the positioning problem in underdetermined condition with the same physical element number.
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Xiaotian Luan,Yankui Wang 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.6
Objective: Cervical cancer is one of the most common malignant tumors. Our previous results showed that long non-coding RNA (lncRNA) XLOC_006390 plays an important role in cervical cancer. In this study, we have explored the mechanism of action of lncRNA XLOC_006390. Methods: LncRNA XLOC_006390 was proposed to exercise its function as a competing endogenous RNA (ceRNA), and its potential targeted miRNAs was predicted through the database LncBase Predicted v.2. Two miRNAs, miR-331-3p, and miR-338-3p, were chosen for the study. Expression of miRNAs and lncRNA in cervical cancer cells and tissues was detected by reverse transcription polymerase chain reaction. To determine the correlation, silencing of XLOC_006390, over-expression of miR-331-3p, and miR-338-3p was performed in SiHa and Caski cell lines, respectively. Results: Based on the interactive effect between miRNA and lncRNA, miR-331-3p and miR-338-3p were significantly downregulated in cervical cancer cells and tissues, and their expression levels were negatively related to that of lncRNA. Our results also showed that the expression of miR-331-3p target gene NRP2, miR-338-3p target genes PKM2, EYA2 was significantly downregulated when the XLOC_006390 was knocked down. Further, XLOC_006390 was found to facilitate cervical cancer tumorigenesis and metastasis by downregulating miR-331-3p and miR-338-3p expression. Conclusion: Taken together, our study demonstrated that XLOC_006390 may serve as a ceRNA and reversely regulates the expression of miR-331-3p and miR-338-3p, thus facilitating cervical cancer tumorigenesis and metastasis.
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Biao Yang,Lin Zhao,Tian Tian,Yankui Qin,Changyu Liu 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.5
The “S” characteristics of a pump turbine may result in certain problems, such as excessive water hammer pressure, unstable no-load operation, and difficulty in synchronization. Accordingly, a new start-up strategy based on the partial opening of a ball valve is proposed, and the calculation model of the hydraulic transition process with misaligned guide vane devices (MGV) and a ball valve is established. The emergency shutdown and turbine start-up conditions are simulated and analyzed. The ball valve can more effectively reduce the maximum inlet pressure of the volute and increase the minimum inlet pressure of the draft tube during the shutdown process compared with the MGV devices. The newly proposed strategy can also effectively reduce the amplitude of pressure fluctuation at the volute and draft tube, shorten the synchronization time, and reduce the speed overshoot during the start-up process. The ball valve can effectively improve the operating quality of the unit in the S-shaped area.
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