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      • KCI등재
      • KCI등재

        이동통신 멀티미디어 데이터서비스의 트래픽 특성 모델링 및 성능분석

        정용주,백천현,김후곤,최택진,양원석,황흥석 한국경영과학회 2003 한국경영과학회지 Vol.28 No.2

        The aim of this study is to identify the data traffic capacity of 3G mobile communication networks, especially of cdma2000-1X networks. Three-layered ON/OFF traffic model is used to describe the dynamics of data traffics and the process of data transmission such as packet scheduling. We construct a simulator fully incorporating packet handling process of cdma2000-1X data network as well as three-layered ON/OFF traffic model describing the behavior of source data traffics. To get influence of traffic parameters on performance measures, the extensive simulations were performed for several data sets which are obtained from real trace data or previous studies. The experimental results show that the engineered throughput satisfying QoS criteria is approximately 20% of total capacity. Finally, some proposals to improve the system capacity are followed.

      • KCI등재

        The USP21/YY1/SNHG16 axis contributes to tumor proliferation, migration, and invasion of non-small-cell lung cancer

        Pei Xu,Haibo Xiao,Qi Yang,Rui Hu,Lianyong Jiang,Rui Bi,Xueyan Jiang,Lei Wang,Ju Mei,Fangbao Ding,Jianbing Huang 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-

        Deubiquitinases (DUBs) and noncoding RNAs have been the subjects of recent extensive studies regarding their roles in lung cancer, but the mechanisms involved are largely unknown. In our study, we used The Cancer Genome Atlas data set and bioinformatics analyses and identified USP21, a DUB, as a potential contributor to oncogenesis in nonsmall-cell lung cancer (NSCLC). We further demonstrated that USP21 was highly expressed in NSCLCs. We then conducted a series of in vitro and in vivo assays to explore the effect of USP21 on NSCLC progression and the underlying mechanism involved. USP21 promoted NSCLC cell proliferation, migration, and invasion and in vivo tumor growth by stabilizing a well-known oncogene, Yin Yang-1 (YY1), via mediating its deubiquitination. Furthermore, YY1 transcriptionally regulates the expression of SNHG16. Moreover, StarBase bioinformatics analyses predicted that miR4500 targets SNHG16 and USP21. A series of in vitro experiments indicated that SNHG16 increased the expression of USP21 through miR-4500. In summary, the USP21/YY1/SNHG16 axis plays a role in promoting the progression of NSCLC. Therefore, the USP21/YY1/SNHG16/miR-4500 axis may be a potential therapeutic target in NSCLC treatment.

      • KCI등재

        시설노인의 자아존중감과 우울

        박금자,이지현,배경의,강양희,송후승 노인간호학회 2007 노인간호학회지 Vol.9 No.1

        Purpose: The purpose of this study was to identify levels of self-esteem and depression in the elders who are residents in welfare facilities and to provide basic data for developing nursing intervention programs for these people. Methods: The participants in this study were 192 older people who scored 24 or higher on the K-MMSE (Korean-Mini Mental State Examination), and have lived for three months or more in one of 4 institutions located in B Metropolitan City. The data were collected by structured questionnaire from August 1 to 20 2006 and frequency, percentage, mean and standard deviation, and Pearson correlation coefficient were used to analyze the data with the SPSS/12.0 program. Results: 1. The score for self-esteem of the participants was 33.70± 7.20 (tool range: 10-50), and for depression, 6.57±3.98 (tool range: 0-15). 2. There was a slightly negative correlation between self-esteem and depression (r=-.388, p=.000). 3. There were significant differences in self-esteem according to education level (F=4.486, p= .012), and level of intention to be admitted to facility (F=7.504, p=-.000). 4. There was significant difference in depression according to education level (F=3.832, p=.023), type of religion (F=3.837, p= .005), level of intention to be admitted to facility (F=7.987, p=.000). Conclusion: This study might help in developing nursing intervention programs to improve self-esteem and reduce depression these elders.

      • SCIESCOPUSKCI등재

        Study on the design and experimental verification of multilayer radiation shield against mixed neutrons and γ-rays

        Hu, Guang,Hu, Huasi,Yang, Quanzhan,Yu, Bo,Sun, Weiqiang Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.1

        The traditional methods for radiation shield design always only focus on either the structure or the components of the shields rather than both of them at the same time, which largely affects the shielding performance of the facilities, so in this paper, a novel method for designing the structure and components of shields simultaneously is put forward to enhance the shielding ability. The method is developed by using the genetic algorithm (GA) and the MCNP software. In the research, six types of shielding materials with different combinations of elements such as polyethylene (PE), lead (Pb) and Boron compounds are applied to the radiation shield design, and the performance of each material is analyzed and compared. Then two typical materials are selected based on the experiment result of the six samples, which are later verified by the Compact Accelerator Neutron Source (CANS) facility. By using this method, the optimal result can be reached rapidly, and since the design progress is semi-automatic for most procedures are completed by computer, the method saves time and improves accuracy.

      • KCI등재후보

        An Efficient Biometric Identity Based Signature Scheme

        ( Yang Yang ),( Yupu Hu ),( Leyou Zhang ) 한국인터넷정보학회 2013 KSII Transactions on Internet and Information Syst Vol.7 No.8

        The combination of biometrics and cryptography gains a lot of attention from both academic and industry community. The noisy biometric measurement makes traditional identity based cryptosystems unusable. Also the extraction of key from biometric information is difficult. In this paper, we propose an efficient biometric identity based signature scheme (Bio-IBS) that makes use of fuzzy extractor to generate the key from a biometric data of user. The component fuzzy extraction is based on error correction code. We also prove that the security of suggested scheme is reduced to computational Diffie-Hellman (CDH) assumption instead of other strong assumptions. Meanwhile, the comparison with existing schemes shows that efficiency of the system is enhanced.

      • A study of Ultrasonic guided wave NDT Technique based on PEEK rod

        Yang Hu,Ma Wenliang,Wang Zhaoba 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.8

        The ultrasonic buffer rod used for polymer testing under the high temperature, not only needs high transmission ultrasound characteristic of SNR, but also low acoustic attenuation, high temperature and strong mechanical properties etc are needed. The role PEEK rod plays in this paper is transmitting ultrasonic guided waves and temperature buffer, so the design of PEEK rod is the key. Through the experimental analysis, the SNR with different diameter and length is gave, and the effect on the ultrasonic characteristics of echo signal is also presented, in order to ensure the high SNR. The conclusions provide a theoretical basis for NDT.

      • KCI등재

        Dynamics analysis of novel parallel manipulator with one central rotational actuator and four translational actuators

        Yang Lu,Yi Lu,Yang Liu,Bo Hu,Yufeng Gong 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.6

        A dynamics analysis of a novel parallel manipulator with one central rotational actuator and four translational actuators is conducted. A 3D model of the parallel manipulator is constructed and its characteristics and DoF are analyzed. The kinematics formulae are derived for solving the displacement, velocity and acceleration of the moving links. The dynamics formulae are derived for solving the inertial wrench of the moving links, the dynamic active forces along the active limbs, the dynamic active torque applied on a central active leg, and the dynamic constrained force exerted on the central active leg. A theoretical numerical example is given to solve the kinematics and dynamics solutions, and the theoretical solutions are verified by the simulation mechanism in Matlab. Finally, a reachable workspace of the novel parallel manipulator is constructed using CAD variation geometry.

      • KCI등재

        Effects of Selenizing Modification on Characteristics and Antioxidant Activities of Inonotus obliquus Polysaccharide

        Yang Hu,Shanyi Shi,Lu Lu,Chunying Teng,Sumei Yu,Xin Wang,Min Yu,Jinsong Liang,Juanjuan Qu 한국고분자학회 2017 Macromolecular Research Vol.25 No.3

        Excessive reactive oxygen species is implicated in the etiology and pathology of many acute and chronic diseases. Selenium acts as an antioxidant and stimulates the creation of more antioxidants. Selenizing modification polysaccharides potentiate the physiological and pharmacological activities of selenium and polysaccharide. In this study, Inonotus obliquus polysaccharide (IOP) extracted from cultured mycelia was modified into Se-IOP by HNO3- Na2SeO3 method. The characteristics and antioxidant activity of IOP and Se-IOP were comparatively investigated. The result showed that polysaccharide content of purified IOP was 98.9%. The selenium content of Se-IOP was 0.71 mg/g. Both IOP and Se-IOP were homogeneous polysaccharides with a molecular weight of 37.354 and 28.071 kDa, respectively depicted in high performance gel permeation chromatogram (HPGPC). Moreover, both IOP and Se- IOP were composed of Man, Glu, and Gal with a molar ratio of 7.7:32.6:23.3 and 8.3:32.1:22.7, respectively determined by high performance liquid chromatography (HPLC). The characteristic absorption peak of O-Se-O, Se=O and C-O-Se appeared at 1026.75, 772.82, and 652.29 cm-1 respectively in FT-IR spectrum of Se-IOP indicating the success of selenylation. NMR spectrum further confirmed the anomeric carbon signals and chemical shifts in IOP and Se-IOP. These variations induced by selenylation may lead to a higher antioxidant activity of Se-IOP on scavenging hydroxyl, 2,2-diphenyl-1-picryl-hydrazyl (DPPH) and superoxide radical than that of IOP. Furthermore, Se- IOP treatment could also reduce oxidant damage by decreasing the level of malondialdehyde (MDA) and increasing the activities of superoxidedismutase (SOD) and GSH-Px in mice.

      • IGF-1 from Adipose-Derived Mesenchymal Stem Cells Promotes Radioresistance of Breast Cancer Cells

        Yang, Hui-Ying,Qu, Rong-Mei,Lin, Xiao-Shan,Liu, Tong-Xin,Sun, Quan-Quan,Yang, Chun,Li, Xiao-Hong,Lu, Wei,Hu, Xiao-Fang,Dai, Jing-Xing,Yuan, Lin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

        Purpose: The aim of this study was to investigate effects of adipose-derived mesenchymal stem cells (AMSCs) on radioresistance of breast cancer cells. Materials and Methods: MTT assays were used to detect any influence of AMSC supernatants on proliferation of breast cancer cells; cell migration assays were used to determine the effect of breast cancer cells on the recruitment of AMSCs; the cell survival fraction post-irradiation was assessed by clonogenic survival assay; ${\gamma}$-H2AX foci number post-irradiation was determined via fluorescence microscopy; and expression of IGF-1R was detected by Western blotting. Results: AMSC supernatants promoted proliferation and radioresistance of breast cancer cells. Breast cancer cells could recruit AMSCs, especially after irradiation. IGF-1 derived from AMSCs might be responsible for the radioresistance of breast cancer cells. Conclusions: Our results suggest that AMSCs in the tumor microenvironment may affect the outcome of radiotherapy for breast cancer in vitro.

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