Research on Building of a Professional Learning Community for China’s Urban and Rural Primary & Secondary School Teachers - Take Hefei City in Anhui Province as an Example -

Shi xiu Lu,Moon bo Sim 한국지역복지정책연구회 2016 지역복지정책 Vol.27 No.-

사회적 공평과 공정은 국가의 건강성과 수준을 평가하는 중요한 기준이 되며, 국민의 권리이자 존엄성을 보장하는 척도다. 교육에서의 공평성은 공평한 사회를 이루기 위한 기초이자 방법이기도 하다. 중국은30여 년의 개혁개방을 통해 종합적 국력이 거대하게 향상되었고, 사회경제가 빠르게 발전된 반면 그 빈부격차도 갈수록 커지고 있다. 이러한 경제적 불평등은 교육에도 반영되고 있다. 도시와 농촌 간, 지역 간, 계층 간에 존재하는 교육적 자원 및 기회 등의 불균형 현상은 이미 사회적 공평성을 해치고 사회적 조화에 악영향이 끼치고 있다. 특히 도시와 농촌간의 불균형은 날로 심해져 교사 부족 현상으로 나타나고 있다. 이러한 문제점을 해결하기 위해서 중국 정부는 농촌 학교 교사 육성과 교육 재배치 등 여러 정책을 잇따라 발표해 왔고 많은 조치를 실행해 왔다. 예컨대, ‘특설직장’계획, 도농(都農) 교사교류 제도, 도농 교육공동체 설립, 교사지원계획 등등. 본 논문은 중국 안휘성 합비시의 도농학교 교사학습공동체설립 상황과 그 문제점을 파악하여, 향후 교사전공 학습공동체 설립에 참고자료로 제공하고자 함이 그 연구 목적이다. 연구에는 교육공평이론, 학습형 조직이론과 교육생태학 이론을 운용하였으며, 설문조사와 인터뷰 그리고 문헌분석 방법으로 안휘성 합비시의 도농학교 교육공동체 안의 교사학습공동체를 조사하여, 다섯 가지 구체적 문제점을 제시하였다. 첫째, 교사전공학습공동체의 주체가 단편적이다. 둘째, 교사 교류의 실효성이 낮다. 셋째, 교사학습공동체 구성원간의 협력의지가 부족하다. 넷째, 교사전공학습공동체의 현대 정보화 기술 운용이 미흡하며, 이른바 교사학습공동체가 널리 설립되어 있지 않다. 다섯째, 학교가 교사전공학습공동체에 제공하는 경비 및 제도적 지원이 제한적이다. 이러한 문제점에 대한 개선책으로 첫째, 교사학습공동체 설립의 주체를 다원화하고 교사학습공동체의 참여도를 향상시켜야 한다. 둘째, 교사교류시스템을 효율화해야 한다. 셋째, 협력공생이라는 교사 협력 문화를 제고하고 팀학습 의식과 능력을 향상시켜야 한다. 넷째, 인터넷 및 현대 정보화기술을 충분히 활용하고 교사학습공동체의 조직을 다양화해야 한다. 다섯째, 교사전공학습공동체에 대한 각 방면의 지원을 증대시켜야 한다.

Determination of Protein, Fat, Starch, and Amino Acids in Foxtail Millet [Setaria italica (L.) Beauv.] by Fourier Transform Near-Infrared Reflectance Spectroscopy

Xiu-Shi Yang,Li-Li Wang,Xian-Rong Zhou,Shaomin Shuang,Zhi-Hua Zhu,Nan Li,Yan Li,Fang Liu,San-Cai Liu,Ping Lu,Guixing Ren,Chuan Dong 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.6

Quantitative detection of protein, fat, starch,and amino acids in foxtail millet using Fourier transformnear-infrared spectroscopy (NIRS) was investigated. Foxtail millet samples (n=259) were analyzed using NIRS. Spectral data were linearized with data from chemicalanalyses. Calibration models were established using apartial least-squares (PLS) algorithm with cross-validation. Optimized models were tested using external validation setsamples with coefficients of determination in the externalvalidation (R2val) of >0.90. Residual predictive deviation(RPD) values were nearly equal to or >2.5 for crudeprotein, alanine, aspartic acid, glutamic acid, isoleucine,leucine, and serine. However, for glycine, histidine,phenylalanine, proline, threonine, tyrosine, and valine, theR2val values were >0.83 and RPD values were nearly equalto or >2.0. For crude fat, total starch, arginine, and lysine,the R2val values were >0.70 and RPD values were >1.5. NIRS is a rapid determination tool for foxtail milletbreeding, and for quality control.

In Vitro Activities of 3-Hydroxy-1,5,6-trimethoxy-2-methyl-9,10- anthraquinone against Non-small Cell Lung Carcinoma

Shi-Xiu Feng,Caigan Du,Qiunong Guan,Tao Chen 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.7

Medicinal herbs are the preferred candidates for drug discovery against human diseases including cancer. The roots of Prismatomeris connata have been used in traditional herbal medicine to treat many health problems, particularly pneumoconiosis. This study was to test the anti-tumor activity of 3-Hydroxy-1,5,6-trimethoxy-2-methyl-9,10-anthraquinone (PCON6), a major anthraquinone derivative from C. connata, against lung cancer. Cell viability in cultures was assessed by MTT assay. Cell death or apoptosis was determined with Annexin-V and 7-Aminoactinomycin D staining. Cell cycle was analyzed by both propidium iodide DNA staining and BrdU incorporation assay. Here we showed that in a panel of fifteen different tumor cells lines, a group of four non-small cell lung carcinoma (NSCLC) cell lines exhibited a relatively higher sensitivity to PCON6 growth inhibition than the rest of most non-lung cancer cell lines (p = 0.0461). Further studies demonstrated that the suppression of NSCLC H520 cell growth by PCON6 was associated with its induction of apoptosis at 20 μM (p = 0.0008), and of cell accumulation at S phase cell cycle (p < 0.05) that was further supported by a decrease in cdc2 protein expression. This preliminary study suggests that natural compound PCON6 has relatively selective cytotoxicity against NSCLC growth and represent a concept of developing a novel drug therapy specific for NSCLC based on the roots of C. connata or PCON6.

Systematic Analysis of Icotinib Treatment for Patients with Non-Small Cell Lung Cancer

Shi, Bing,Zhang, Xiu-Bing,Xu, Jian,Huang, Xin-En Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.13

Purpose: This analysis was conducted to evaluate the efficacy and safety of icotinib based regimens in treating patients with non-small cell lung cancer (NSCLC). Methods: Clinical studies evaluating the efficacy and safety of icotinib-based regimens with regard to response and safety for patients with NSCLC were identified using a predefined search strategy. Pooled response rates of treatment were calculated. Results: With icotinib-based regimens, 7 clinical studies which including 5,985 Chinese patients with NSCLC were considered eligible for inclusion. The pooled analysis suggested that, in all patients, the positive reponse rate was 30.1% (1,803/5,985) with icotinib-based regimens. Mild skin itching, rashes and diarrhea were the main side effects. No grade III or IV renal or liver toxicity was observed. No treatment-related death occurred in patients treated with icotinib-based regimens. Conclusions: This evidence based analysis suggests that icotinib based regimens are associated with mild response rate and acceptable toxicity for treating Chinese patients with NSCLC.

Development of a position sensitive CsI(Tl) crystal array

Shi, Guo-Zhu,Chen, Ruo-Fu,Chen, Kun,Shen, Ai-Hua,Zhang, Xiu-Ling,Chen, Jin-Da,Du, Cheng-Ming,Hu, Zheng-Guo,Fan, Guang-Wei Korean Nuclear Society 2020 Nuclear Engineering and Technology Vol.52 No.4

A position-sensitive CsI(Tl) crystal array coupled with the multi-anode position sensitive photomultiplier tube (PS-PMT), Hamamatsu H8500C, has been developed at the Institute of Modern Physics. An effective, fast, and economical readout circuit based on discretized positioning circuit (DPC) bridge was designed for the 64-channel multi-anode flat panel PSPMT. The horizontal and vertical position resolutions are 0.58 mm and 0.63 mm respectively for the 1.0 × 1.0 × 5.0 ㎣ CsI(Tl) array, and the horizontal and vertical position resolutions are 0.86 mm and 0.80 mm respectively for the 2.0 × 2.0 × 10.0 ㎣ CsI(Tl) array. These results show that the CsI(Tl) crystal array with low cost could be applied in the fields of medical imaging and high-resolution gamma camera.

Identification of the Varieties and Analysis on Genetic Relationships of Wild and Cultivated Species of Vaccinium spp. in China Using RAPD Markers

Xiu Ying Xia,Na Xu,Da Ke Xu,Jun Yang,Yu Shi Luan 한국유전학회 2008 Genes & Genomics Vol.30 No.1

The genetic relationships among 17 clones of Vaccinium (Vaccinium spp.), including 2 Northeast Chinese wild species and 15 commercial cultivars were evaluated through a Random Amplified Polymorphic DNA(RAPD)analysis of young leaves. The Rapids generated a total of 115 markers with 15 random primers, of which 98.26% were found to be polymorphic. These RAPD markers could successfully separate individuals from the 17 samples and detect variations in the Vaccinium species. Genetic similarity and genetic distance were measured by Nei`s unbiased measurement. Using arithmetic averages (UPGMA) dendrogram, the unweighted pair-group method indicated that 17 samples were classified into three major groups: two groups of each wild species, and one group of 15 cultivars. The 15 cultivars could be clearly assigned into two subgroups of which the only lowbush sample (Blomidon) was clustered in one subgroup and the other 14 cultivars were clustered in one subgroup. The cluster results had some relativity with the pedigree of cultivars. These indicated that the polymorphic RAPD markers developed in this study should have general utility for identification of the varieties and examination of genetic relationships in blueberry.

Alu Tandem Sequences Inhibit GFP Gene Expression by Triggering Chromatin Wrapping

Xiu Fang Wang,Xiao Yan Wang,Jing Liu,Jing Jing Feng,Wen Li Mu,Xiao Juan Shi,Qin Qing Yang,Xiao Cui Duan,Ying Xie,Zhan Jun Lu 한국유전학회 2009 Genes & Genomics Vol.31 No.3

Alu elements belonging to the short interspersed nuclear elements (SINE) of repetitive elements are present in more than one million copies which altogether represent 10% of the whole human genome. In this study, the roles of Alu tandem sequences in the process of GFP gene (GFP) expression and packing into chromatin of its DNA were studied. To detect the effect of Alu repeats on gene expression, different copies of Alus were inserted GFP downstream respectively in pEGFP-C1 vector. We found that Alu sequences decreased the amount of GFP transcription, the percentage of GFP positive cells and the accessibility to DNase I in length-dependent manner. Inserting Alu caused the production of higher-molecular-mass RNA, indicating Alu sequence did not induce premature transcriptional termination. Tight packing chromatins keep silent and resist to DNase I digestion, which is a general phenomenon. We suggested that head and tail tandem Alu sequences suppressed GFP expression in length dependent manner by triggering chromatin packing.

Oleanolic Acid Inhibits Neuronal Pyroptosis in Ischaemic Stroke by Inhibiting miR-186-5p Expression

Shi-Chang Cai,Xiu-Ping Li,Xing Li,Gen-Yun Tang,Li-Ming Yi,Xiang-Shang Hu 한국뇌신경과학회 2021 Experimental Neurobiology Vol.30 No.6

Ischaemic stroke is a common condition leading to human disability and death. Previous studies have shown that oleanolic acid (OA) ameliorates oxidative injury and cerebral ischaemic damage, and miR-186-5p is verified to be elevated in serum from ischaemic stroke patients. Herein, we investigated whether OA regulates miR-186-5p expression to control neuroglobin (Ngb) levels, thereby inhibiting neuronal pyroptosis in ischaemic stroke. Three concentrations of OA (0.5, 2, or 8 μM) were added to primary hippocampal neurons subjected to oxygen–glucose deprivation/reperfusion (OGD/R), a cell model of ischaemic stroke. We found that OA treatment markedly inhibited pyroptosis. qRT–PCR and western blot revealed that OA suppressed the expression of pyroptosis-associated genes. Furthermore, OA inhibited LDH and proinflammatory cytokine release. In addition, miR-186-5p was downregulated while Ngb was upregulated in OA-treated OGD/R neurons. MiR-186-5p knockdown repressed OGD/R-induced pyroptosis and suppressed LDH and inflammatory cytokine release. In addition, a dual luciferase reporter assay confirmed that miR-186-5p directly targeted Ngb. OA reduced miR-186-5p to regulate Ngb levels, thereby inhibiting pyroptosis in both OGD/R-treated neurons and MCAO mice. In conclusion, OA alleviates pyroptosis in vivo and in vitro by downregulating miR-186-5p and upregulating Ngb expression, which provides a novel theoretical basis illustrating that OA can be considered a drug for ischaemic stroke.

Accumulation and Distribution Patterns of Pahs and Trace Metals in Forest Floors

Xiu-Hong Yang,Shi-Zhong Wang,Rong-Liang Qiu,Zhi-Wen Fang,Xiong-Fei Huang,Dan Mo 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Value of 3-Dimensional CT Virtual Anatomy Imaging in Complex Foreign Body Retrieval from Soft Tissues

Xiu-Jun Yang,Guang-Fu Xing,Chang-Wen Shi,Wei Li 대한영상의학회 2013 Korean Journal of Radiology Vol.14 No.2

Objective: To investigate the value of 3-dimensional (3D) CT virtual anatomy imaging (VAI) in the complex foreign body (FB) retrieval of the soft tissues. Materials and Methods: Four hundred and seventy-five patients with radiopaque FB(s) diagnosed by radiograph underwent contrast-enhanced 3D CT examination. VAI was reconstructed by volume-rendering opacity software, by sliding down the lowest threshold from -600 to 100 HU. The imaging was grouped into three groups: A (axial and multi-planar reformation [MPR] images), B (standard 3D imaging with axial and MPR images), and C (VAI with axial and MPR images). They were analyzed to reveal the type, size, number, location, complications, and the interventional removability of the object, with the comparisons in the management and clinical outcomes on the patient follow-up studies. The data were subjected to chi-square tests, with p value < 0.05 indicating significant statistical difference. Results: The FB shape, size, number, site distribution and vessels around FB, as well as the FB-associated vascular complications and the FB interventional removability were assessed more accurately in Group C than in Group B or Group A (p < 0.005). There was no significant difference in disclosing the type and depth of the FB among the three groups (p > 0.75). On the basis of the 3D CT, especially the enhanced 3D CT VAI, the followings were processed: the recommendation of interventional removal in 286 (60.47%) and non-intervention in 187 (39.53%) of the 473 patients with soft-tissue FB(s); in 352 (56.50%) of the 623 radiopaque FBs patients, 258 (54.55%) patients accurately detected on 3D CT and the successful removal by intervention (343 FBs) or surgery (9 FBs) without any sequela; and 215 (45.45%) patients with 271 FBs lost in the follow-up, with their departure from the hospital. Conclusion: The 3D CT, especially 3D enhanced CT VAI, has great incremental value in further diagnosis and management of complex FB extraction from soft tissues.