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Xinling Cao,Guanping Zhang,Tao Li,Chengming Zhou,Lei Bai,Jinming Zhao,Turgunjan Tursun 한국유전학회 2020 Genes & Genomics Vol.42 No.11
Background Hepatocellular carcinoma (HCC) is the sixth most commonly diagnosed malignant tumor and the fourth leadingcause of cancer-related deaths worldwide. As a novel non-coding RNA, LINC00657 was firstly identified as an oncogenicrole in breast cancer. However, few research focus on the effect of LINC00657 on the progression of HCC. Objectives The purpose of this study was to investigate the effect of LINC00657 on HCC tissues and cells, and furtherexplore the potential mechanism. Methods We first measured the expression of LINC00657 in HCC tissues and cell lines using qRT-PCR. Next we establishedLINC00657 knockdown in HCC cells. CCK-8 assay, cell invasion assay, flow cytometry analysis, qRT-PCR and westernblotting were applied to assess the role of LINC00657 knockdown in the biological behavior of HCC cells. The bioinformaticsanalysis and the rescue experiment were devoted to the underlying mechanism. Results LINC00657 was remarkably overexpressed in HCC tissues and cell lines, associated with poor prognosis. LINC00657knockdown repressed cell proliferation and invasion, promoted cell apoptosis of HCC cell lines. The bioinformatics analysisshowed LINC00657 sponged miR-424 as a ceRNA. Besides, PD-L1 mimic rescued the suppression of si-LINC00657 inthe biological behavior of HCC cells. Conclusion In a word, we observed LINC00657 regulated PD-L1 expression by sponging miR-424, thus affecting the developmentsof hepatocellular carcinoma. These findings LINC00657 may provide new evidence for therapeutic application inhepatocellular carcinoma.
A Novel Intrusion Detection Approach Based on Chaos Theory in Wireless Sensor Network
Xinling Kong,Yonghong Chen,HuiTian,Tian Wang,Yiqiao Cai 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.11
With the development of technology, wireless sensor networks(WSNs) has been widely used in military, political, medical and other fields, their characteristics of data-centric become increasingly prominent. In this paper, a data-oriented intruding detection method based on chaos theoy is proposed. We use the theory of chaotic system to analyze the internal rules of the sensory data and predict the data by RBF neural network firstly, then make an initial detection of false injected data attack according to whether the difference between the predicted and actual value is more than the threshold, finally confirming the attack by checking whether the number of abnormal within the cycle lies in the corresponding range. Experimental results show that RBF neural network predict sensory data more accurate, our approach can effectively distinguish the abnormal events caused by the attack or environmental factors and has high intrusion detection accuracy.
Aminated cassava residue-based magnetic microspheres for Pb(II) adsorption from wastewater
Xinling Xie,Jie Huang,Youquan Zhang,Zhangfa Tong,Anping Liao,Xingkui Guo,Zuzeng Qin,Zhanhu Guo 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.2
Aminated cassava residue magnetic microspheres (ACRPM) were synthesized via an inverse emulsion method by using chemically modified cassava residue as a crude material, and acrylic acid (AA), acrylamide (AM), and methyl methacrylate (MMA) as monomers and a polyethylene glycol/methanol system (PEG/MeOH) as the porogen. Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), N2 adsorption-desorption and vibrating sample magnetometry (VSM) were used to characterize the ACRPM. The results indicated that amino groups were grafted to the cassava residue magnetic microspheres, and the Fe3O4 nanoparticles were encapsulated in the microspheres. After porogen was added, the particle size of the ACRPM decreased from 16.5 μm to 150 nm with a pore volume of 0.05510m3/g, and the specific surface area of the ACRPM increased from 3.02 to 12.34m2/g. The ACRPM were superparamagnetic, and the saturation magnetization was 9.8 emu/g. The maximum adsorption capacity of Pb(II) on the ACRPM was 390mg/g. The ACRPM exhibited a large specific surface area and provided many adsorption sites for metal ion adsorption, which favored a high adsorption capacity. Additionally, the Pb(II) adsorption process was fitted to pseudo-second-order kinetic and Langmuir isothermal adsorption models. This suggests that the Pb(II) adsorption process was dominated by a chemical reaction process and that chemisorption was the rate-controlling step during the Pb(II) removal process. In addition, the adsorbent exhibited good stability after six consecutive reuses.
Tensile Behavior of High-Strength Stainless Steel Wire Rope (HSSSWR)-Reinforced ECC
Xinling Wang,Guanghua Yang,Wenwen Qian,Ke Li,Juntao Zhu 한국콘크리트학회 2021 International Journal of Concrete Structures and M Vol.15 No.6
Engineered cementitious composites (ECC) show the distinguished characteristics of high post-cracking resistance and ductility. High-strength stainless steel wire rope (HSSSWR) has been successfully used for restoring or strengthening of existing structures. By combining the advantages of these two materials, a new composite system formed by embedding HSSSWR into ECC was proposed and expected to be a promising engineering material for repair or strengthening of structures. To investigate the tensile failure mechanism and mechanical properties of HSSSWR-reinforced ECC, an experimental study on 27 HSSSWR-reinforced ECC plates was conducted considering the effects of the reinforcement ratio of longitudinal HSSSWRs, formula of ECC and width of the plate. Test results revealed that HSSSWR-reinforced ECC exhibit superior post-cracking resistance, deformation capacity and crack-width control capacity. Increasing the reinforcement ratio of longitudinal HSSSWRs can effectively enhance the tensile strength, crack-width control capacity, deformation capacity and tensile toughness of HSSSWR-reinforced ECC. Adding thickener in ECC can significantly improve the crack-width control capacity and deformation capacity of HSSSWR-reinforced ECC due to enhancing uniform distribution of polyvinyl alcohol fibers, but would slightly reduce the cracking stress and maximum tensile stress by bringing small bubbles in the matrix. The tensile properties of HSSSWR-reinforced ECC plates are almost not affected by varying the plate width. Besides, a tensile constitutive model was developed for charactering the stress-strain relationship of HSSSWR-reinforced ECC in tension. Based on mechanical theories and failure characteristics of HSSSWR-reinforced ECC, the model parameters were determined, and calculation equations of cracking stress and tensile strength were proposed. The accuracy of the developed model and calculation equations was verified by test results.
Xinling Li,Shihua Fu,Jianjun Wang 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.1
This paper addresses the robust stabilization problem of Boolean control networks with disturbance inputs (DBCNs) via the semi-tensor product (STP) of matrices, and designs all feasible state feedback stabilizers. Based on the algebraic form of DBCNs, some necessary and sufficient conditions are derived for the robust stabilization of DBCNs by Ledley antecedence solution technique. An algorithm is proposed to determine all complete families of robust reachable sets, moreover, all feasible state feedback stabilizers are obtained. Finally, two numerical examples are exploited to illustrate the effectiveness of the proposed results as well as the controller design scheme.
Xinling Zhang,Ning Yuan,Shuo Xu,Yi Li,Qibao Wang 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.111 No.-
The removal of organic pollutants was examined by new zeolitic imidazolate framework-8/carboxyl-functionalized multi-walled carbon nanotubes (ZIF-8/MWCNTs-COOH) nanoadsorbents, which were preparedvia controlling the reaction sequence of MWCNTs-COOH with the precursors of ZIF-8. Structuralmorphology and chemical composition characterizations confirmed the successful preparation of ZIF-8/MWCNTs-COOH nanoadsorbents. The obtained samples manifested a preferable adsorption capacityfor Congo red with the maximum adsorption capacity of 1185.58 mg g1 with an adsorption removal rateof 97.93% at equilibrium adsorption. Further analyses indicated that the adsorption process conformed tothe pseudo-second-order kinetic model and Langmuir adsorption isotherm. The thermodynamic analyseswere depicted as endothermic, entropy-increasing, and spontaneous. The effects of pH value, interferingions, and dosage on the adsorption properties were systematically explored. The nanoadsorbent can beexpediently reused for eight cycles without a prominent reduction in adsorption activity. The improvedperformance and high reusability can be ascribed to the increasing specific surface, the presence of electrostaticinteraction, hydrogen bonding, and p–p interaction between ZIF-8/MWCNTs-COOH and organicmolecules. In addition, the prepared composites also showed a better adsorption performance for tetracyclinewith the equilibrium adsorption capacity of 471.22 mg g1 compared to pure ZIF-8 and MWCNTs-COOH.
Thin-film electronics based on all-2D van der Waals heterostructures
Liu Xinling,Yang Xiaomin,Sang Weihui,Huang Hai,Li Wenwu,Lin Yen-Fu,Chu Junhao 한국정보디스플레이학회 2021 Journal of information display Vol.22 No.4
Two-dimensional (2D) layered materials including metal, semiconductor, and insulator have received extensive attention in recent years. The weak van-der-Waals (vdW) interactions between 2D materials layers enable them to isolate monolayers and restack into artificial 2D vdW heterostructures in the desired sequence. These assembled all-2D vdW heterostructures are promising platforms for fabricating next-generation electronics as well as optoelectronics. In particular, the all-2D vdW heterostructure devices composed entirely of 2D layered material have received extensive attention due to their natural thickness, atomically sharp heterointerfaces, and excellent mechanical flexibility. Herein, we firstly introduce 2D vdW heterostructures and their preparation methods. Secondly, the recent progress of field-effect transistors (FETs) and photodetectors based on all-2D vdW heterostructures are summarized. Finally, we discuss some challenges of all-2D vdW heterostructure-based devices for practical applications and offer personal perspectives toward the future development of thin-film electronics.
체육교사의 자율성지지가 고등학교 학습자의 관계성지지와 또래 동기 분위기에 미치는 영향
LU XINLING,천승현,송용관 한국체육학회 2023 한국체육학회지 Vol.62 No.3
이 연구는 교사의 자율성지지가 고등학교 학습자의 관계성지지와 또래 동기 분위기에 어떤 영향을 미치는지 규명하였다. 이를 위해, 고등학생 734명(남학생 511명, 여학생 223명)을 대상으로 체육수업에서 인식하고 있는 교사의 자율성지지와 동료의 관계성지지 그리고 또래 동기 분위기 수준을 측정하였다. 수집된 자료는 통계프로그램을 통해, 기술, 신뢰도, 타당도, 상관 및 경로분석을 수행하였다. 분석결과, 첫째, 교사의 자율성지지는 동료의 관계성지지에 유의한 정적 영향을 미치는 것으로 밝혀졌다. 둘째, 교사의 자율성지지는 과제중심 동기 분위기에 유의한 정적 영향을 미쳤고, 자아중심 동기 분위기에는 유의한 부적 영향을 미친 것으로 확인되었다. 셋째, 동료의 관계성지지는 또래 동기 분위기 하위요인인 과제중심 동기 분위기에 유의한 정적 영향을 미치는 것으로 밝혀졌다. 이는 교사의 자율성지지가 학생들과의 동료 관계 형성과 유지에 긍정적인 영향을 미친다는 것을 의미한다. 그리고 매개효과 분석에서 알 수 있듯이, 교사의 자율성지지에 영향을 받은 동료의 관계성지지는 서로 노력하고, 함께하면서 성장하는 과제중심 동기 분위기에 긍정적으로 작용한다는 것을 보여준다. 이는, 동료의 관계성지지의 질적 제고를 위해서는 교사의 자율성지지가 중요한 역할을 한다는 것을 시사한다. 결론적으로 교사와 학생의 긍정적인 상호작용뿐 아니라, 학생들이 서로 좋은 관계를 맺고 상호협력을 통해 체육의 가치를 높이기 위해서는 교사의 상호소통방식이 중요한 사회적 환경이라는 것을 보여준다.
周新玲(Zhou Xinling) 중국어문학연구회 2012 중국어문학논집 Vol.0 No.75
Word combination in this essay refers to the broadest definition instead of the narrowest one, i.e., restricted combination, which was put forward by Firth, leader of the London School. An investigation at SISU spanning 3 semesters on word combinations is made on 5 stages: freshman, sophomore first semester, sophomore second semester, junior and senior. The data provides a scientific backing for the word combination teaching in Grade 2. On the whole, the acquisition of Liheci and free combination are above average, especially that of Liheci is the most satisfactory; whereas that of semi-fixed combination and fixed combination are below average, the acquisition of semi-fixed combination are lower than that of fixed combination in Grade 4. The reason is three-tiered: whether the textbook and the teacher have provided enough correct input, whether the students have had enough output opportunities under teacher’s monitoring, whether the interaction between the teacher and the students is enough and high-quality.