Electrochemical Formation of a <i>p–n</i> Junction on Thin Film Silicon Deposited in Molten Salt

Zou, Xingli,Ji, Li,Yang, Xiao,Lim, Taeho,Yu, Edward T.,Bard, Allen J. American Chemical Society 2017 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.139 No.45

<P>Herein we report the demonstration of electrochemical deposition of silicon <I>p–n</I> junctions all in molten salt. The results show that a dense robust silicon thin film with embedded junction formation can be produced directly from inexpensive silicates/silicon oxide precursors by a two-step electrodeposition process. The fabricated silicon <I>p–n</I> junction exhibits clear diode rectification behavior and photovoltaic effects, indicating promise for application in low-cost silicon thin film solar cells.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/2017/jacsat.2017.139.issue-45/jacs.7b09090/production/images/medium/ja-2017-09090m_0004.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja7b09090'>ACS Electronic Supporting Info</A></P>

Effects of Exogenous Ghrelin on the Behaviors and Performance of Weanling Piglets

Wu, Xingli,Tang, Maoyan,Ma, Qiugang,Hu, Xinxu,Ji, Cheng Asian Australasian Association of Animal Productio 2008 Animal Bioscience Vol.21 No.6

The objective of this study was to evaluate the effect of exogenous ghrelin on the behaviors, weight gain, and feed intakes of weanling piglets. A total of 25 pairs of Duroc$\times$Landrace$\times$Large White piglets weaned at 21 days of age were used in this experiment which finished on day 36. Each pair of healthy piglets from the same litter with similar body weight and of the same gender were selected and randomly arranged to ghrelin or control groups. Thus, there were 50 piglets (ghrelin 25; control 25) kept in 10 pens (ghrelin 5; control 5) and 5 piglets per pen. Initial body weight of the pigs did not differ between the control and ghrelin treatment ($7.43{\pm}0.17kg$; p = 0.81). Experimental pigs were infused with ghrelin ($1{\mu}g/d$ pig) via the marginal ear vein between 0750 and 0800 h at 22, 23, 24 days of age. Control pigs were infused with 0.9% saline. Feed consumption was measured on days 23, 24, 25, 29 and 36. Body weight was measured on days 22, 23, 24, 25, 29 and 36. Behavior data of individual piglets were collected by real-time observation from 0800-1500 h through remote supervisory equipment at 22, 23 and 24 days of age. The results indicated that ghrelin infusion could increase drinking (p<0.05) and lying behaviors (p<0.01) and decrease mounting behaviors (p<0.05). No significant influence of ghrelin was found on average daily weight gain (ADG) and average daily feed intake (ADFI) in this experiment (p>0.05). In conclusion, exogenous ghrelin by the method above and at the dosage of $1{\mu}g/d$ pig could cause a variety of behavioral effects, but not improve performance of weanling piglets.

Overexpression of miR-155-5p Inhibits the Proliferation and Migration of IL-13-Induced Human Bronchial Smooth Muscle Cells by Suppressing TGF-β-Activated Kinase 1/MAP3K7-Binding Protein 2

Yujia Shi,Xingli Fu,Qi Cao,Zhengdao Mao,Yi Chen,Yun Sun,Zhiguang Liu,Qian Zhang 대한천식알레르기학회 2018 Allergy, Asthma & Immunology Research Vol.10 No.3

Purpose: Molecular mechanisms leading to asthma is still ill-defined. Though the function of microRNAs (miRNAs) in asthma was previously reported, the involvement of miR-155 in important features of this disease remains unknown. The present study was designed to uncover the probable involvement of miR-155-5p in the proliferation and migration of IL-13-induced human bronchial smooth muscle cells (BSMCs) and the intrinsic regulatory mechanism. Methods: The effects of different concentrations of IL-13 on the proliferation and migration of BSMCs as well as the expression of miR-155-5p and its predicted target transforming growth factor (TGF)-β-activated kinase 1/MAP3K7-binding protein 2 (TAB2) were investigated. The effects of miR-155-5p on the proliferation and migration of interleukin (IL)-13-induced BSMCs was determined in vitro using BSMCs transfected with miR-155 mimic/inhibitor and induced by a high concentration of IL-13. The quantitative real-time polymerase chain reaction (qRT-PCR) was employed for determining the expression of miR-155-5p and TAB2. Western blotting was applied to analyze the expression of TAB2 at the protein level. Cell proliferation and migration were assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and Transwell assays, respectively. Results: The proliferation and migration of BSMCs were dose-dependently increased with IL-13 treatment. Contrariwise, IL-13 dose-dependently inhibited the expression of miR-155-5p in BSMCs. Mechanistic studies showed that inhibition of miR-155-5p further promoted the stimulatory effects of IL-13, whereas overexpression of miR-155 significantly inhibited these effects. In silico studies and luciferase reporter assays indicated that TAB2 was a negatively regulated miR-155-5p target. Conclusions: These results suggested that miR-155-5p-inhibit the IL-13-induced proliferation and migration of BSMCs by targeting TAB2 and that the IL-13/miR-155/TAB2 pathway could serve as a therapeutic target for pulmonary diseases, especially asthma.

Carbon Medicine in Ancient China

Hongyan Yang,Zengxiang Fu,Xingli Huang,Binrui Ma 한국탄소학회 2005 Carbon Letters Vol.6 No.4

In traditional Chinese medicine, some herbs are used after toasting or roasting. The process is called "Zhi Tan" in Chinese, which means charring, and the herbs after the treatment is called carbon medicine. Carbon medicine is widely used to arrest bleeding in traditional Chinese medicine. The paper introduces the records, development and applications of carbon medicine in ancient China. The earliest record found about carbon medicine was in the remains of Han dynasty (BC206-A.D.8). The paper also introduces the process of charring herbs and mechanism of carbon medicine in arresting bleeding. Calcium iron and tan released during the charring are believed as main factors for arresting bleeding, helped with porous surface structure of active carbon.

Trapping tephritid fruit flies (Diptera: Tephritidae) in citrus groves of Fujian Province of China

Yulu Xia,Gecheng Ouyang,Xingli Ma,Bohua Hou,Jinghao Huang,Hanqing HU,Guocheng Fan 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.4

Certain tephritid fruit flies, such as the oriental fruit fly, Bactrocera dorsalis, the Chinese citrus fly, B. minax and the Japanese orange fly, B. tsuneonis (Diptera: Tephritidae: Dacinae), are destructive citrus pests in China. A twoyear trapping study was conducted in pomelo, Citrus maxima, groves in Fujian Province of China. The objectives of this study were to investigate the species, the abundance of tephritid fruit flies in the orchards, as well as the efficacy of the selected lure traps to these flies. Four lure traps or devices, i.e. methyl eugenol + Steiner trap (ST), cuelure + ST, ammonium acetate + putrescine + ST, and sticky spheres, were deployed from June to November 2017 and April to October 2018. Six economically significant Dacini pests were trapped during the period. These flies are B. dorsalis, the melon fruit fly, Zeugodacus cucurbitae, the pumpkin fruit fly, Z. tau, the Malaysian fruit fly, B. latifrons, and other two species - B. rubigina and Z. scutellatus. B. dorsalis was the most abundant, accounting for more than 50% of the capture, followed by Z. cucurbitae. The remaining four species accounted for less than 2% of the total capture. B. minax and B. tsuneonis, two destructive citrus-damaging tephritid fruit flies in China, were not found during the trapping period. Methyl eugenol trapped the highest number of fruit flies, followed by cuelure.

Simulation Analysis of Cylinder Impact Performance Influenced by Shaft Sleeve Structure

Cong Liu,Pei Xiao,Xingli Li,Gangyan Li 한국유체기계학회 2018 International journal of fluid machinery and syste Vol.11 No.1

To study the cylinder motion characteristics, cylinder and shaft sleeve stress characteristics of cylinder stroke and return process influenced by different shaft sleeve structure, the cylinders with non-chamfering shaft sleeve, C0.3 chamfering shaft sleeve and R0.3 round corner shaft sleeve were used for simulation of cylinder stroke and return process. The results show that the piston velocity curves of three kinds of shaft sleeve are identical. Maximum stress of different shaft sleeves fluctuates and maximum stress elements of C0.3 and R0.3 shaft sleeve are similar. When cylinder strokes, maximum stress of cylinder occurs at the end of piston rod connected to the load; the stress of C0.3 shaft sleeve is the lowest. When cylinder returns, maximum stress of cylinder occurs at the shaft sleeve; the stress of C0.3 and R0.3 shaft sleeve differ little and are both lower than that of non-chamfering shaft sleeve. It provides a reference for structure optimization and service life improvement of the cylinder shaft sleeve.

Carbon Medicine in Ancient China

Yang, Hongyan,Fu, Zengxiang,Huang, Xingli,Ma, Binrui Korean Carbon Society 2005 Carbon Letters Vol.6 No.4

In traditional Chinese medicine, some herbs are used after toasting or roasting. The process is called "Zhi Tan" in Chinese, which means charring, and the herbs after the treatment is called carbon medicine. Carbon medicine is widely used to arrest bleeding in traditional Chinese medicine. The paper introduces the records, development and applications of carbon medicine in ancient China. The earliest record found about carbon medicine was in the remains of Han dynasty (BC206-A.D.8). The paper also introduces the process of charring herbs and mechanism of carbon medicine in arresting bleeding. Calcium iron and tan released during the charring are believed as main factors for arresting bleeding, helped with porous surface structure of active carbon.

Simulation Analysis of Cylinder Impact Performance Influenced by Shaft Sleeve Structure

Liu, Cong,Xiao, Pei,Li, Xingli,Li, Gangyan Korean Society for Fluid machinery 2018 International journal of fluid machinery and syste Vol.11 No.1

To study the cylinder motion characteristics, cylinder and shaft sleeve stress characteristics of cylinder stroke and return process influenced by different shaft sleeve structure, the cylinders with non-chamfering shaft sleeve, C0.3 chamfering shaft sleeve and R0.3 round corner shaft sleeve were used for simulation of cylinder stroke and return process. The results show that the piston velocity curves of three kinds of shaft sleeve are identical. Maximum stress of different shaft sleeves fluctuates and maximum stress elements of C0.3 and R0.3 shaft sleeve are similar. When cylinder strokes, maximum stress of cylinder occurs at the end of piston rod connected to the load; the stress of C0.3 shaft sleeve is the lowest. When cylinder returns, maximum stress of cylinder occurs at the shaft sleeve; the stress of C0.3 and R0.3 shaft sleeve differ little and are both lower than that of non-chamfering shaft sleeve. It provides a reference for structure optimization and service life improvement of the cylinder shaft sleeve.

MicroRNA-375 is a therapeutic target for castration-resistant prostate cancer through the PTPN4/STAT3 axis

Gan Junqing,Liu Shan,Zhang Yu,He Liangzi,Bai Lu,Liao Ran,Zhao Juan,Guo Madi,Jiang Wei,Li Jiade,Li Qi,Mu Guannan,Wu Yangjiazi,Wang Xinling,Zhang Xingli,Zhou Dan,Lv Huimin,Wang Zhengfeng,Zhang Yanqiao,Q 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

The functional role of microRNA-375 (miR-375) in the development of prostate cancer (PCa) remains controversial. Previously, we found that plasma exosomal miR-375 is significantly elevated in castration-resistant PCa (CRPC) patients compared with castration-sensitive PCa patients. Here, we aimed to determine how miR-375 modulates CRPC progression and thereafter to evaluate the therapeutic potential of human umbilical cord mesenchymal stem cell (hucMSC)-derived exosomes loaded with miR-375 antisense oligonucleotides (e-375i). We used miRNA in situ hybridization technique to evaluate miR-375 expression in PCa tissues, gain- and loss-of-function experiments to determine miR-375 function, and bioinformatic methods, dual-luciferase reporter assay, qPCR, IHC and western blotting to determine and validate the target as well as the effects of miR-375 at the molecular level. Then, e-375i complexes were assessed for their antagonizing effects against miR-375. We found that the expression of miR-375 was elevated in PCa tissues and cancer exosomes, correlating with the Gleason score. Forced expression of miR-375 enhanced the expression of EMT markers and AR but suppressed apoptosis markers, leading to enhanced proliferation, migration, invasion, and enzalutamide resistance and decreased apoptosis of PCa cells. These effects could be reversed by miR-375 silencing. Mechanistically, miR-375 directly interfered with the expression of phosphatase nonreceptor type 4 (PTPN4), which in turn stabilized phosphorylated STAT3. Application of e-375i could inhibit miR-375, upregulate PTPN4 and downregulate p-STAT3, eventually repressing the growth of PCa. Collectively, we identified a novel miR-375 target, PTPN4, that functions upstream of STAT3, and targeting miR-375 may be an alternative therapeutic for PCa, especially for CRPC with high AR levels.

NAMDANG’S THEORY ON THE NATURES OF HUMANS AND NON-HUMAN LIVING BEINGS AND HIS DEVELOPMENT OF ZHU XI’S THEORIES

XING LIJU,LIN XI 계명대학교 한국학연구원 2016 Acta Koreana Vol.19 No.2

This article examines a thesis by Namdang, a Confucian scholar in Chosŏn Korea, on the natures of humans and non-human living beings, using Zhu Xi’s li (理) - qi (氣) theory. Regarding the sameness or difference between li and qi, Zhu Xi formulated different opinions in his early and later life and was also at times inconsistent in his works of a certain period. To a certain extent, Zhu Xi’s thoughts lacked coherence, which led to subsequent debates. In seeking to develop Zhu Xi’s li-qi theory, Namdang put forward his original thesis of Trichotomous Nature, which significantly enriched Zhu Xi’s ideas. The “nature transcending the appearance of things” (K. ch’ohyŏnggi 超形氣) refers to a pure xing (K. sŏng 性; nature), concerned with only li without considering the influence of qi from the perspective of a unitary source (K. irwŏn 一原; one source). At this stage, everything shares the same li and xing. The “nature originated from temperament” (K. in’gijil 因氣質) demonstrates the shared nature for the same species as well as the difference in nature across species, thus being an endowmentdependent li. At this stage, for the same species, they share the same li, qi, and xing, while for varying species, there is a difference in li, qi, and xing. The “nature mixed with temperament” (K. chapkijil 雜氣質) considers the xing of pure qizhi (K. kijil 氣質; physical temperament) in which all creatures differ. It is thus a concept that demonstrates the particularity in all things, with varying differences in li, qi, and xing.