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      • KCI등재

        AFLP Molecular Markers Linked to the Pear Scab Resistance Gene

        Xingguang Dong,Shenghua Lin,Fei Wang,Zhigang Wang,Li Fan,Chengquan Fang 한국원예학회 2010 Horticulture, Environment, and Biotechnology Vol.51 No.2

        Pear scab (caused by Venturia nashicola) is one of the most harmful diseases in pear. Molecular markers closely linked to scab resistance genes will be greatly useful for improving pear breeding by marker-assisted selection. In our study, a F₁ population (139 individuals) from the cross ‘Huangguan’ (Resistance) and ‘Yali’ (Susceptible) was analyzed, and bulked segregant analysis (BSA) was conducted to find AFLP fragments linked to the locus of scab resistance in pear. Out of 64 fluorescent AFLP primers, two markers showed polymorphisms between the resistant-bulk and the susceptible-bulk, as well as between the parents. D3-365 were found linked to the resistance locus. By using selective genotype analysis, the genetic distances between the marker and the resistant locus were 14.9cM.

      • KCI등재

        Experimental investigation using an acrylamide-based polymer with emulsifying capability for enhanced oil recovery: A preliminary study

        Xingguang Xu,Jian Ouyang,Yuanyuan Wang,Chao Wang 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.57 No.-

        This work presents the synthesis and characterization of a new polymer, named AVS, which not onlythickens the displacingfluid at high salinity and/or elevated temperature, but also emulsifies the crudeoil. The results demonstrate AVS solution displays 50% higher apparent viscosity than the commonly usedhydrolysed polyacrylamide (HPAM) solution in the same testing conditions. Furthermore, compared toHPAM, AVS has greater capacity to resist the shearing stress. Finally, coreflooding experiments verify theAVS solution recovers more incremental oil than HPAM solution does, which is mostly attributed to itsoutstanding ability to simultaneously enhance the sweep efficiency and the displacement efficiency.

      • KCI등재

        Experimental investigation using an acrylamide-based polymer with emulsifying capability for enhanced oil recovery: A preliminary study

        Xingguang Xu,Jian Ouyang,Yuanyuan Wang,Chao Wang 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.55 No.-

        This work presents the synthesis and characterization of a new polymer, named AVS, which not only thickens the displacing fluid at high salinity and/or elevated temperature, but also emulsifies the crude oil. The results demonstrate AVS solution displays 50% higher apparent viscosity than the commonly used hydrolysed polyacrylamide (HPAM) solution in the same testing conditions. Furthermore, compared to HPAM, AVS has greater capacity to resist the shearing stress. Finally, core flooding experiments verify the AVS solution recovers more incremental oil than HPAM solution does, which is mostly attributed to its outstanding ability to simultaneously enhance the sweep efficiency and the displacement efficiency.

      • KCI등재

        The study of m-pentadecylphenol on the inhibition of mild steel corrosion in 1 M HCl solution

        Emanuel X. Ricky,Musa Mpelwa,Xingguang Xu 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.101 No.-

        The acidic fluids used in the acidification of oil wells provoke corrosion of metallic materials unenviably. As a consequence, corrosion inhibitors are needed to mitigate or retard the corrosion process. Herein, wereport m-pentadecylphenol as an eco-friendly corrosion inhibitor in acidic media developed from cashewnut shell liquid (CNSL), which is a low-cost and sustainable source. The inhibitor was evaluated as corrosioninhibitor for mild in 1 M HCl corrosive solution by potentiodynamic polarization (PDP), electrochemicalimpedance spectroscopy (EIS), weight loss, Fourier transform infrared (FT-IR) spectroscopy,atomic force microscopy (AFM), and energy-dispersive X-ray fluorescence (EDX-RF) spectrometry methods. The results showed that the inhibition efficiency of m-pentadecylphenol was at least 95% at an optimalconcentration (300 ppm). The inhibition efficiency was found to increase as the inhibitorconcentration increments from 100 to 300 ppm. Further studies revealed the inhibition performance ofm-pentadecylphenol to be marginally reliant on temperature as the temperature rises from 303 to333 K. At 333 K, the inhibition performance of the inhibitor was still promising (about 85%) when theconcentration was 300 ppm. The adsorption studies revealed the spontaneous aptitude of mpentadecylphenolto inhibit corrosion by forming a non-conductive inhibitive layer on the mild steel surfacemainly through the chemisorption mechanism. The chemisorption adsorption was satisfactorilydescribed by the Langmuir adsorption isotherm model. Besides, the potentiodynamic polarization measurementsrevealed m-pentadecylphenol to act as an anodic inhibitor. The overall findings revealed thatm-pentadecylphenol to be an effective corrosion inhibitor in harsh corrosive vicinities with the addedadvantages of being eco-friendly and relatively cheaper. Thus, it can replace the use of non-green andexpensive corrosion inhibitors in the industry.

      • KCI등재

        Bubble breakup dynamics and flow behaviors of a surface-functionalized nanocellulose based nanofluid stabilized foam in constricted microfluidic devices

        Bing Wei,Yuanyuan Wang,Yangbing Wen,Xingguang Xu,Colin Wood,Lin Sun 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.68 No.-

        Nanocellulose was surface-functionalized toward the applications in enhanced oil recovery (EOR) as a green alternative. The focus of this paper is on the effect of this material based nanofluid (NF) on foam lamella stabilization through studying its bubble breakup dynamics and flow behaviors in constricted mircofluidic devices. The NF stabilized foam produced an improved flow resistance across the capillary largely due to the capillary trapped bubbles at the contraction. The “snap-off” caused the NF stabilized foam to produce finer textured bubbles, which can migrate readily forward to the deep porous media, as revealed by the pressure profiles.

      • KCI등재

        Sex difference of autosomal alleles in populations of European and African descent

        Lingjun Zuo,Tong Wang,Xiandong Lin,Jijun Wang,Yunlong Tan,Xiaoping Wang,Xueqing Yu,Xingguang Luo 한국유전학회 2015 Genes & Genomics Vol.37 No.12

        In the present study, we aimed to report the individual sex-different genetic markers across autosomes in European- and African-origin populations. A total of 8400 females and 8081 males in 19 independent cohorts were genotyped across genomes using Illumina or Affymetrix arrays. The allele frequencies were compared between females and males in nine non-clean cohorts (with some human disease traits) using genome-wide logistic regression and then the nominally significant associations were replicated across 10 clean cohorts (without disease traits). Meta-analysis was performed to derive the combined p values across all cohorts. We found 13 markers that were genome-wide significant (p B 5 9 10-8) between females and males in the meta-analysis of all cohorts of European descent, including rs7740449 at SYNE1, rs7531151 at PLD5, rs697455 at PPP1R12B, rs6745746 at LOC100128413, rs17000079 at PARM1, rs11948070 at PDE4D, rs7801825 at INSIG1, rs9551642 at MTUS2, rs2932174 at TPTE2, rs1961597 at SALL3, rs4117529 at METTL4, rs6021473 at SALL4 and rs6092466 at RAE1, and one marker, i.e., rs10145208 at PCNX, that was genomewide significant in the meta-analysis of all cohorts of African descent. The most robust finding was rs7740449 at SYNE1, next to ESR1. We conclude that there are many sex-different markers on autosomes. These markers may be informative in differentiating females and males.

      • KCI등재

        Loss of KDM5B ameliorates pathological cardiac fibrosis and dysfunction by epigenetically enhancing ATF3 expression

        Wang Bo,Tan Yong,Zhang Yunkai,Zhang Sheng,Duan Xuewen,Jiang Yuyu,Li Tong,Zhou Qingqing,Liu Xingguang,Zhan Zhenzhen 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

        Excessive cardiac fibrosis is central to adverse cardiac remodeling and dysfunction leading to heart failure in many cardiac diseases. Histone methylation plays a crucial role in various pathophysiological events. However, the role of histone methylation modification enzymes in pathological cardiac fibrosis needs to be fully elucidated. Here, we identified lysine demethylase 5B (KDM5B), a histone H3K4me2/me3 demethylase, as a key epigenetic mediator of pathological cardiac fibrosis. KDM5B expression was upregulated in cardiac fibroblasts and myocardial tissues in response to pathological stress. KDM5B deficiency markedly ameliorated cardiac fibrosis, improved cardiac function, and prevented adverse cardiac remodeling following myocardial infarction (MI) or pressure overload. KDM5B knockout or inhibitor treatment constrained the transition of cardiac fibroblasts to profibrogenic myofibroblasts and suppressed fibrotic responses. KDM5B deficiency also facilitated the transformation of cardiac fibroblasts to endothelial-like cells and promoted angiogenesis in response to myocardial injury. Mechanistically, KDM5B bound to the promoter of activating transcription factor 3 (Atf3), an antifibrotic regulator of cardiac fibrosis, and inhibited ATF3 expression by demethylating the activated H3K4me2/3 modification, leading to the enhanced activation of TGF-β signaling and excessive expression of profibrotic genes. Our study indicates that KDM5B drives pathological cardiac fibrosis and represents a candidate target for intervention in cardiac dysfunction and heart failure.

      • KCI등재

        A comprehensive review on CO2 thickeners for CO2 mobility control in enhanced oil recovery: Recent advances and future outlook

        Emanuel X. Ricky,Grant Charles Mwakipunda,Edwin E. Nyakilla,Naswibu A. Kasimu,Chao Wang,Xingguang Xu 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.126 No.-

        Carbon dioxide (CO2) has been utilized to recover the residual oil from the geological reservoirs throughenhanced oil recovery (EOR) methods for over 50 years. Despite its long history of success as an EOR technique,CO2 flooding recovers only about 20–40% of the original oil in place (OOIP) from the geologicalreservoirs. The small amount of oil recovered by CO2 flooding is associated with the low viscosity ofCO2 injected into the reservoir, resulting in CO2 viscous fingering, CO2 gravity override and unfavourablemobility. To address these problems, the CO2 viscosity needs to be enhanced considerably using CO2thickeners or viscosifiers. Despite more than five decades of intensive research work in formulatingand identifying effective CO2 thickeners such as polymers, surfactants, small molecules and nanoparticles;as yet none of these chemicals can be regarded as effective CO2 thickeners for EOR field applications. Thus, CO2 thickener is an interesting research topic for future studies to come up with effective andaffordable CO2 thickeners for EOR field applications. This article presents the recent developments inCO2 thickening technologies in EOR. Furthermore, the CO2 thickening mechanisms, screening criteria,field scale applications, challenges and future research directions on CO2 thickeners are evaluated.

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