Numerical simulations and surrogate-based optimization of cavitation performance for an aviation fuel pump

Xing’an Zhao,Biao Huang,Tairan Chen,Guoyu Wang,Deming Gao,Jing Zhao 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.2

We used computational modeling to investigate the cavitation performance of an aviation fuel pump, and optimize structural parameters using the surrogate-based method. In the numerical simulation, a rotation-curvature correction was adapted to the k-ε turbulence model, and a four-component surrogate fuel was selected to reproduce the physical properties of the China RP-3 kerosene. Then the performance of the aviation fuel pump was predicted. In the optimization, based on the series of the numerical results, Surrogate-based analysis and optimization (SBAO) was used to optimize the structural parameters of the fuel pump (the variation of the outlet blade angle for the inducer △β b1 and the variation of the inlet blade angle for the impeller △β b2 ). The results show that the prediction of cavitation performance agrees well with the experimental data. The results show that cavitation areas are mainly distributed in the inlet of the inducer. The volume of cavities grows with the decreasing NPSHa. The head of the fuel pump has a sudden head-drop when NPSHa ≤ 5.64 m. Furthermore, the surrogate-based approach is available in structural optimization of the fuel pump. The cavitation performance of the optimized pump improved about 22 % with a little drop of head coefficient when △β b1 = 4.33° and △β b2 = 3.24°. The numerical approach employed in this paper can accurately predict the cavitating flow of the high rotating speed fuel pump and the surrogate-based method is available in the structural optimization for a better cavitation performance.

A novel design method for improving collapse resistances of multi-story steel frames with unequal spans using steel braces

Zheng Tan,Wei-hui Zhong,Bao Meng,Shi-chao Duan,Hong-chen Wang3,Xing-You Yao,Yu-hui Zheng 국제구조공학회 2023 Steel and Composite Structures, An International J Vol.47 No.2

The bearing capacities resisted by the two-bay beams of multi-story planar frames with unequal spans under column removal scenarios differ considerably owing to the asymmetric stress on the left and right beams connected to the failed column and cause the potential for beams with larger span-to-depth ratios to be unable to exert effectively, which is disadvantageous for resisting the vertical load in unequal-span frame structures. To address this problem, the structural measure of adding braces to the weak bays of multi-story unequal-span frames was proposed, with the objective of achieving a coordinated stress state in two-bay beams with unequal spans, thereby improving the collapse resistance of unequal-span frame structures. Before conducting the numerical simulation, the modeling methods were verified by previous experimental results of two multi-story planar frames with and without steel braces. Thereafter, the effects of the tensile and compressive braces on the collapse behavior of the frame structures were elucidated. Then, based on the mechanical action laws of the braces throughout the collapse process, a detailed design method for improving the collapse resistance of unequal-span frame structures was proposed. Finally, the proposed design method was verified by using sufficient example models, and the results demonstrated that the design method has good application prospects and high practical value.

Recommendations on management of gynecological malignancies during the COVID-19 pandemic: perspectives from Chinese gynecological oncologists

Yingmei Wang,Shiqian Zhang,Lihui Wei,Zhongqiu Lin,Xinyu Wang,Jianliu Wang,Keqin Hua,Manhua Cu,Jiandong Wang,Shixuan Wang,Wen Di,Yudong Wang,Ruifang An,Mingrong Xi,Ruixia Guo,Qi Zhou,Xing Xie,Fengxia X 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.4

The outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratorysyndrome coronavirus 2 has rapidly spread globally. Cancer patients are at a higher risk ofbeing infected with the coronavirus and are more likely to develop severe complications, ascompared to the general population. The increasing spread of COVID-19 presents challengesfor the clinical care of patients with gynecological malignancies. Concerted efforts should beput into managing gynecological malignancies in an orderly manner by strictly implementingthe measures that are specifically developed for controlling the spread of COVID-19. We havedrafted Recommendations on Management of Gynecological Malignancies during the COVID-19 Pandemicbased on our experience on controlling COVID-19 pandemic in China. We recommendthat patients with gynecological malignancies should be managed in hierarchical andindividualized manners in combination with local conditions related to COVID-19. Medicalcare decision should be balanced between controlling COVID-19 pandemic spread and timelydiagnosis and treatment for gynecologic oncology patients.

Performance Assessment of InSAR-Based Vertical Displacement Monitoring of Sluices in Coastal Soft Soil Area

Xing Yang,Dongmei Wang,Yongping Xu,Miao Hou,Zhihuan Wang 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.1

Sluices are main flood control infrastructures in coastal areas, where soft rock and soft soil are widely distributed. In soft soil areas, the vertical displacement of sluice is common, which is the main factor affecting the sluice safety. So, it is very important for sluice safety control according to the prototypical observations on deformation. Considering some drawbacks of leveling, such as it can only provide a limited number of points and requires time-consuming field work, this paper evaluates the performance of Interferometric Synthetic Aperture Radar (InSAR)-based method in monitoring long-term vertical displacement deformations of sluices.Taking 12 sluices in Northern Jiangsu, China as an example, 129 Sentinel-1 C-band VV-polarizatio ascending SAR images that span the period from April 2015 to January 2020 were used to monitor their vertical displacement deformations. The leveling results are made to verify the accuracy and reliability of Permanent Scatterer InSAR (PSInSAR) method. The validation indicates good agreement between PSInSAR results and leveling results. Considering the higher accuracy of leveling, PSInSAR method is more suitable as an auxiliary technology besides leveling method to focus on the early warning of sluice deformation risk events.

Improving Cellulase Production in Trichoderma koningii Through RNA Interference on ace1 Gene Expression

( Wang Shao Wen ),( Miao Xing ),( Gang Liu ),( Shao Wen Yu ),( Juan Wang ),( Sheng Li Tian ) 한국미생물 · 생명공학회 2012 Journal of microbiology and biotechnology Vol.22 No.8

Ribonucleic acid interference (RNAi) inhibits the expression of target genes in a sequence-specific manner, and shows potential for gene knockdown in filamentous fungi, in which the locus-specific gene knockout occurs in low frequency. In this study, the function of the repressor of cellulase expression I (ACEI) was verified in Trichoderma koningii (T. koningii) YC01 through RNAi, and ace1-silenced strains with improved cellulase productivity were obtained. An expression cassette that transcribed the interfering double-stranded RNA (dsRNA) of ace1 was constructed and transformed into T. koningii, and the transformants, in which the expression of ace1 was successfully silenced, were selected. As a result of the ace1 gene silencing, the expression levels of the main cellulase and xylanase genes were elevated, and the enhanced production of total proteins, cellulase, and xylanase was observed in the cultivation. In addition, the downregulation of ace1 resulted in an increasing expression of xyr1, but no clear variation in the expression of cre1, which suggested that ACEI acted as a repressor of the xyr1 transcription, but was not involved in the regulation of the cre1 expression. The results of this work indicate that ace1 is a valid target gene for enhancing enzyme production in T. koningii, and RNAi is an appropriate tool for improving the properties of industrial fungi.

Mapping of QTLs controlling content of fatty acid composition in rapeseed (Brassica napus)

Xing Ying Yan,Jia Na Li,Rui Wang,Meng Yan Jin,Li Chen,Wei Qian,Xin Na Wang,Lie Zhao Liu 한국유전학회 2011 Genes & Genomics Vol.33 No.4

The improvement of fatty acid composition is one of the major goals of breeding in rapeseed (Brassica napus). The aim of this study was to provide more information on the genetic determination of fatty acid composition by investigating quantitative trait loci (QTLs). The study was based on two-year of field trials (in 2006 and 2007) with a population of recombinant inbred lines (RILs), which originated from a cross between GH06 and P174. The level of erucic acid (C22:1) was significantly negatively correlated with those of palmitic acid (C16:0), oleic acid (C18:1), linoleic acid (C18:2), linolenic acid (C18:3), and eicosenoic acid (C20:1) in both years. A total of 40 QTLs for six fatty acids were detected and most of them were clustered on linkage groups N8, N9, and N13. These results suggested strongly that there were significant correlations between the levels of fatty acid components and would be useful for the future improvement of breeding programs focused on fatty acids in rapeseed.

Stathmin is a Marker of Progression and Poor Prognosis in Esophageal Carcinoma

Wang, Feng,Xuan, Xiao-Yan,Yang, Xuan,Cao, Lei,Pang, Li-Na,Zhou, Ran,Fan, Qin-Xia,Wang, Liu-Xing Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8

Stathmin, also called oncoprotein 18, is a founding member of the family of microtubule-destabilizing proteins that play a critical role in the regulation of mitosis. At the same time stathmin has been recognized as one of responsible factors in cancer cells. The aim of this study was to assess stathmin status, its correlations with clinicopathological parameters and its role as a progosnostic marker in EC patients. The protein and mRNA levels of stathmin were examined byimmunohistochemistry (IHC) and in situ hybridization in 100EC tissues and adjacent noncancerous tissues. mRNA and protein expression of stathmin in three EC cell lines(EC9706, ECa109, EC1 commonly used in research) were also analyzed using immunocytochemistry, western blot and in situ hybridization. The prognostic value of Stathmin expression within the tumor tissues were assessed by Cox regression and Kaplan-Meier analysis. We showed that stathmin expression was significantly higher in EC tissues than in adjacent noncancerous tissues. High stathmin immunostaining score in the EC was positively correlated with tumor differentiation, Tumor invasion, Lymph node metastases, and TNM stage. In addition, we demonstrated that three EC cell lines examined, were constitutively expressing a high level of stathmin. Of those, EC-1 showed the strongest mRNA and protein expression for the stathmin analyzed. Kaplan-Meier analysis showed that significantly longer 5-year survival rate was seen in EC patients with high Stathmin expression, compared to those with low expression of Stathmin expression. Furthermore, multivariate Cox proportional hazard analyses revealed that Stathmin was an independent factors affecting the overall survival probability. In conclusion, our data provide a basis for the concept that stathmin might be associated with EC development and progression. High levels of Stathmin expression in the tumor tissues may be a good prognostic marker for patients with EC.

Geometric Optimization of a Mathematical Model of Radiofrequency Ablation in Hepatic Carcinoma

Wang, Kai-Feng,Pan, Wei,Wang, Fei,Wang, Gao-Feng,Madhava, Pai,Pan, Hong-Ming,Kong, De-Xing,Liu, Xiang-Guan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

Radio frequency ablation (RFA) is an effective means of achieving local control of liver cancer. It is a particularly suitable mode of therapy for small and favorably located tumors. However, local progression rates are substantially higher for large tumors (>3.0 cm). In the current study, we report on a mathematical model based on geometric optimization to treat large liver tumors. A database of mathematical models relevant to the configuration of liver cancer was also established. The specific placement of electrodes and the frequency of ablation were also optimized. In addition, three types of liver cancer lesion were simulated by computer guidance incorporating mathematical models. This approach can be expected to provide a more effective and rationale mechanism for employing RFA in the therapy of hepatic carcinoma.

Network Information Security Situation Assessment Based on Bayesian Network

Wang Xing-zhu 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.5

The situation of information security is difficult to be precise, autonomous and controllable. In this situation, the situation of the system is based on Fuzzy Dynamic Bayesian network. The model of situation awareness and situation estimation is constructed. The simulation results are compared with that of static Bayesian network model. The experimental results show that this method can better reflect the dynamic changes of network space operations.

Improvement of the Multiple Image Encryption Capacity Using QR Code as a Data Container

Xing Bai,Jianping Hu,Sheng Yuan,Jinchao Wang,Jing Wang,Xin Zhou 한국광학회 2020 Current Optics and Photonics Vol.4 No.4

An image encryption scheme based on the quick response (QR) code as a data container has aroused wide interest due to the lossless recovery of the decrypted image. In this paper, we apply this method to multi-image encryption. However, since the decrypted image is affected by crosstalk noise, the number of multi-image encryptions is severely limited. To solve this problem, we analyzed the performance of QR code as a data container, and processed the decrypted QR code using the proposed method, so that the number of multi-image encryptions is effectively increased. Finally, we implemented a large image (256 × 256) encryption and decryption.