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      • KCI등재

        Intelligent identification of mortar void in ballastless slab track using the wheelset acceleration combined with CNN-SVM

        Xin Xin,Zunsong Ren,Yi Yin,Jinsheng Gao 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.12

        Mortar void is a hidden defect in ballastless slab track difficult to be efficiently identified by traditional detection methods. This paper is dedicated to proposing a new detection method to identify the mortar void position and length using the vehicle response combined with the hybrid convolutional neural network-support vector machine (CNN-SVM) classifier. The vertical wheelset accelerations with different mortar void conditions are collected from a vehicle-track coupled dynamics simulation model. The first components decomposed from wheelset accelerations by local mean decomposition and their envelopes are utilized as the training data due to their sensitivity to mortar void. To improve the identification precision, the scope descent method is proposed to determine the range influenced by mortar void (IMVR) and samples are labeled according to IMVR. Meanwhile, identification results are post processed based on the mortar void characteristics. The results show that over 90 % mortar void conditions with the length of 0.65 m are detected correctly and the identification has a higher precision with the mortar void length greater than 0.95 m. The proposed technology of mortar void detection using the wheelset accelerations with the hybrid CNN-SVM classifier provides reference for engineering application, which is of great significance to relieve the pressure of health monitoring of railway track.

      • SCOPUSKCI등재
      • KCI등재

        Albumin-to-Fibrinogen Ratio as an Independent Prognostic Parameter in Untreated Chronic Lymphocytic Leukemia: A Retrospective Study of 191 Cases

        Yi-Xin Zou,Jia Qiao,Hua-Yuan Zhu,Rui-Nan Lu,Yi Xia,Lei Cao,Wei Wu,Hui Jin,Wen-Jie Liu,Jin-Hua Liang,Jia-Zhu Wu,Li Wang,Lei Fan,Wei Xu,Jian-Yong Li 대한암학회 2019 Cancer Research and Treatment Vol.51 No.2

        Purpose Chronic lymphocytic leukemia (CLL) is one of the most frequent type of B-cell chronic lymphoproliferative disorders and chronic inflammation takes part in the development of CLL. However, there has been no valid immune biomarker to predict the prognosis of untreated CLL patients. Materials and Methods In this retrospective study, we analyzed the clinical correlations and prognostic value of albumin-to-fibrinogen ratio (AFR) detected at diagnosis in 191 CLL patients. Results The cut-off value of AFR was 9.7 calculated by X-tile. Patients who were more than 65 years old were often accompanied by low level of AFR (p < 0.001). Survival analysis showed that patients with low level of AFR had shorter overall survival (OS) than patients with high level of AFR (p < 0.001). Multivariate analysis illustrated that AFR had a negative impact on OS (p=0.003) and was independent of parameters involved in CLL international prognostic index and other prognostic markers such as CD38 and ZAP-70. Conclusion These data provide a comprehensive view of AFR and shows that AFR at diagnosis is an adverse prognostic factor in untreated CLL patients.

      • KCI등재

        Modeling of low viscosity oil-water annular flow in horizontal and slightly inclined pipes: Experiments and CFD simulations

        Yi-Xin Pan,Hong-Bing Zhang,Rong-Hua Xie,Xing-Bin Liu,Min Wang 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.10

        To characterize the effect of pipe inclination, low viscosity, flow rate and inlet water cut on annular flow pattern, a low viscosity oil-water two-phase annular flow in horizontal and slightly inclined (+1o, +3o and +5o) pipes with diameter of 20 mm has been experimentally investigated. A modified VOF model based on the CFD software package FLUENT was used to predict the in-situ oil fraction and pressure drop. The experimental data indicate that annular flow appears at a medium-high water cut. The slip ratio increases with flow rate increase but decreases with increasing water cut. The changes are more significant as the degree of inclination increases. Pressure drop is strongly dependent on flow rate, as it increases rapidly as inlet flow rate increase. Good agreement between the experimental data and calculated results of slip ratio and pressure drop was obtained.

      • KCI등재

        The Comparative Analysis of 3D Software Virtual and Actual Wedding Dress

        ( Xin-yi Yuan ),( Soo-jeong Bae ) 한국패션비즈니스학회 2017 패션 비즈니스 Vol.21 No.6

        This study is intended to compare an actual wedding dress being made completely through 3D software, and compare it with an actual dress of a real model by using collective tools for comparative analysis. The method of the study was conducted via a literature review along with the production of the dresses. In the production, two wedding dresses for the small wedding ceremony were designed. Each of the design was made into both 3D and an actual garment. The results are as follows. First, the 3D whole body scanner reflects the measure of the exact human body size, however there were some difficulties in matching what the customer wanted, because the difference of the skin color and the hair style. Second, the pattern of the dress is much more easily altered than it was in the real production. Third, the silhouette of the virtual and the actual person with the dress was nearly the same. Fourth, textile tool was much more convenient because of the use of real-time rendering on the virtual dresses. Lastly, the lace and biz decoration were flat, and the luster was duller than in reality. Prospectively, the consumer will decide their own design of variety through the use of the avatar without wearing the actual dresses, and they would demand what the another one desired, different from the presented ones by making the corrections by themselves. Through this process, the consumer would be actively participating in the design, a step which would finally lead to the two way designing rather than the one way design of present times.

      • SCIESCOPUSKCI등재

        Biocatalysis and Fermentation Technology : Thermostable Sites and Catalytic Characterization of Xylanase XYNB of Aspergillus niger SCTCC 400264

        ( Xin Ran Li ),( Hui Xu ),( Jie Xie ),( Qiao Fu Yi ),( Wei Li ),( Dai Rong Qiao ),( Yi Cao ),( Yu Cao ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.4

        In order to improve the expression of heat-resistant xylanase XYNB from Aspergillus niger SCTCC 400264, XynB has been cloned into Pichia pastoris secretary vector pPIC9K. The XynB production of recombinant P. pastoris was four times that of E. coli, and the Vmax and specific activity of XynB reached 2,547.7 umol/mg and 4,757 U/mg, respectively. XynB still had 74% residual enzyme activity after 30 min of heat treatment at 80°C. From the van der Waals force analysis of XYNB (ACN89393 and AAS67299), there is one more oxygen radical in AAS67299 in their catalytic site, indicating that the local cavity is much more free, and it is more optimal for substrate binding, affinity reaction, and proton transfer, etc, and e ventually i ncreasing enzyme activity. The H-bonds analysis of XYNB indicated that there are two more H-bonds in the 33rd Ser of XYNB (AAS67299) than in the 33rd Ala(ACN89393 ), and two H-bonds between Ser70 and Asp67.

      • FA/Mel@ZnO nanoparticles as drug self-delivery systems for RPE protection against oxidative stress

        Yi, Caixia,Yu, Zhihai,Sun, Xin,Zheng, Xi,Yang, Shuangya,Liu, Hengchuan,Song, Yi,Huang, Xiao Techno-Press 2022 Advances in nano research Vol.13 No.1

        Drug self-delivery systems can easily realize combination drug therapy and avoid carrier-induced toxicity and immunogenicity because they do not need non-therapeutic carrier materials. So, designing appropriate drug self-delivery systems for specific diseases can settle most of the problems existing in traditional drug delivery systems. Retinal pigment epithelium is very important for the homeostasis of retina. However, it is vulnerable to oxidative damage and difficult to repair. Worse still, the antioxidants can hardly reach the retina by non-invasive administration routes due to the ocular barriers. Herein, the targeted group (folic acid) and antioxidant (melatonin) have been grafted on the surface of ZnO quantum dots to fabricate a new kind of drug self-delivery systems as a protectant via eyedrops. In this study, the negative nanoparticles with size ranging in 4~6 nm were successfully synthesized. They could easily and precisely deliver drugs to retinal pigment epithelium via eyedrops. And they realized acid degradation to controlled release of melatonin and zinc in retinal pigment epithelium cells. Consequently, the structure of retinal pigment epithelium cells were stabilized according to the expression of ZO-1 and β-catenin. Moreover, the antioxidant capacity of retinal pigment epithelium were enhanced both in health mice and photic injury mice. Therefore, such new drug self-delivery systems have great potential both in prevention and treatment of oxidative damage induced retinal diseases.

      • KCI등재

        A novel bio-inspired approach with multi-resolution mapping for the path planning of multi-robot system in complex environments

        Yi Xin,Zhu Anmin,Li Chaofan,Yang Simon X 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.6

        For multi-robot systems (MRSs), conventional path planning with single resolution mapping is challenging to balance information and computation. Regarding path planning of MRS, the previous research lacked systematic definition, quantitative evaluation, and the consideration of complex environmental factors. In this paper, a new systematic formulation is proposed to redefine the multi-robot path planning problem in complex environments, and evaluate the related solutions of this problem. To solve this problem, a novel bio-inspired approach based on reaction-diffusion system is given to deal with the path planning of MRS in complex environments, such as electromagnetic interference, ocean currents, and so on. Furthermore, a multi-layer neural dynamic network is proposed to describe environments with multiple resolutions, which can improve time performance while ensuring the integrity of environmental information. Comparative experimental results indicate that the proposed approach shows the excellent path planning performance of MRS in complex environments. The stability of the proposed method is determined by the mathematical basis.

      • KCI등재

        중국 상장기업의 자본구조 결정요인

        진이흔(Yi-Xin Qin),강호정(Ho-Jung Kang) 한국콘텐츠학회 2012 한국콘텐츠학회논문지 Vol.12 No.4

        상해증권거래소는 2011년 3월 말 기준 상장 회사 905개, 상장증권 1,537개, 상장주식 949개, 상장주식 총수 2조 2,000억 주, 시가총액 19조 3,000억 위안 규모로 신흥시장의 최대 증권거래소로 자리매김을 하였으며, 앞으로 더욱 많은 발전을 할 것으로 예측되고 있다. 다른 국가의 증권거래소와는 달리 중국의 증권거래소는 상장기업 중 국유기업의 비중이 높은 특징을 지니고 있기 때문에 증권거래소에 상장된 기업들의 자본구조가 어떠한지, 더 나아가 자본구조를 결정하는 요인들이 무엇인지를 파악하는 것은 의미가 있다. 따라서 본 연구의 목적은 중국의 증권거래소 중 신흥시장의 최대 증권거래소로 부상한 중국의 대표적인 증권거래소인 상해증권거래소에 상장된 기업들 중 60%를 차지하고 있는 제조업에 속한 기업들을 대상으로 다중회귀분석을 이용하여 자본구조를 결정하는 요인들이 무엇인지를 파악하는데 있다. 본 연구결과를 요약하면 다음과 같다. 첫째, 기업규모는 부채비율에 1% 유의수준에서 유의적인 정(+)의 영향을 미치는 것으로 나타났다. 둘째, 수익성은 부채비율에 1% 유의수준에서 유의적인 부(-)의 영향을 미치는 것으로 나타났다. 셋째, 성장성은 부채비율에 1% 유의수준에서 유의적인 정(+)의 영향을 미치는 것으로 나타났다. 넷째, 현금흐름, 최대주주 지분율, 유통주 비율은 부채비율에 부(-)의 영향을 미치는 것으로 나타났으나 통계적으로 유의하지 않았다. 본 연구결과는 투자자에 대한 정보제공 및 재무구조 개선의 기초자료로 활용될 수 있다는 점에서 의의가 있다. Shanghai Stock Exchange is the largest stock exchange of emerging markets that there were listed firms 905, listed securities 1,537, listed stocks 949, total number of listed stocks 2 trillion 2000 billion shares. There is more development that is expected to occur in the future . The purpose of this study is to find determinants of capital structure to listed manufacturing firms in Shanghai Stock Exchange using multiple regression. Conclusions of this study are summarized as follows. First, firm size is positively related to debt ratio significantly at 1% significance level.. Second, the profitability is negatively related to debt ratio significantly at 1% significance level. Third, the growth ability is positively related to debt ratio significantly at 1% significance level. fourth, cash flow, the largest shares ownership, negotiable shares ratio are negatively related to debt ratio but they are not significant statistically. The result of this study provides information for investors and can be utilized to improvement of financial structure.

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