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Xiaohu Su,Shenyuan Wang,Guangqi Gao,Xinyu Zho,Lidong Han,Guanghua Su,Jiaqi Zhang,Wanfu Bai,Xiuying Wang,Guangpeng Li,Li Zhang 한국유전학회 2020 Genes & Genomics Vol.42 No.3
Background The development efficiency of cloned cattle is extremely low (< 5%), most of them were aborted at late gestation. Based on our previous studies, some recipient cows with a cloned fetus would present as engorged uterine vessels and enlarged umbilical vessels randomly. Abortion involves both maternal and fetal factors. Objective Our aim was to explore this phenomenon by microRNAs expression profile analysis of maternal corpus luteum (CL), which was related to pregnancy maintenance. Methods The present study provided the comparison of maternal CL miRNAs expression of abnormally and normally developed cloned bovine fetus at late gestation (~ 210 days) using RNA-Seq technology. Results We selected two abnormally pregnant cows (abnormal group, AG) and three normally pregnant cows (normal group, NG) and acquired valid reads of 9317,261–12,327,185 (~ 84.53–91.28%) from five libraries. In total, we identified 981 conserved miRNAs and 223 novel miRNAs. 1052 miRNAs were co-expressed, 124 miRNAs were uniquely expressed in AG, and 93 miRNAs were uniquely expressed in the NG. Compared with NG, 11 were significantly overexpressed, and 22 were downregulated (p < 0.05) at AG among 1052 co-expressed miRNAs. The differentially expressed miRNAs-targeted genes were further analyzed by Gene Ontology and KEGG pathway analysis. Notably, the steroid biosynthesis pathway was a significantly enriched term (p < 0.01), which may affect the secretion of progesterone. Conclusion Our research suggested that abnormal miRNAs expression of bovine maternal CL may affect the pregnant status at late gestation.
AFSO: An Adaptative Frame Size Optimization Mechanism for 802.11 Networks
( Xiaohu Ge ),( Cheng-xiang Wang ),( Yang Yang ),( Lei Shu ),( Chuang Liu ),( Lin Xiang ) 한국인터넷정보학회 2010 KSII Transactions on Internet and Information Syst Vol.4 No.3
In this paper, we analyze the impact of different frame types on self-similarity and burstiness characteristics of the aggregated frame traffic from a real 802.11 wireless local area network. We find that characteristics of aggregated frame traffic are affected by both mean frame size and the proportion of specified frame types. Based on this new knowledge, an adaptative frame size optimization (AFSO) mechanism is proposed to improve the transmission efficiency by adaptively adjusting data frame size according to the proportions of different frame types. Simulation results show that our proposed mechanism can effectively regulate the burstiness of aggregated frame traffic and improve the successful delivery rate of data frames when a fixed throughput target is set for 802.11 wireless networks.
Xiaohu Zhao,Qian Xi,Peijun Wang,Chunbo Li,Hongjian He 대한영상의학회 2014 Korean Journal of Radiology Vol.15 No.4
Objective: The prior functional MRI studies have demonstrated significantly abnormal activity in the bilateral superior temporal gyrus (STG) of anxiety patients. The purpose of the current investigation was to determine whether the abnormal activity in these regions was related to a loss of functional connectivity between these regions. Materials and Methods: Ten healthy controls and 10 anxiety patients underwent noninvasive fMRI while actively listening to emotionally neutral words alternated by silence (Task 1) or threat-related words (Task 2). The participants were instructed to silently make a judgment of each word’s valence (i.e., unpleasant, pleasant, or neutral). A coherence analysis was applied to the functional MRI data to examine the functional connectivity between the left and the right STG, which was selected as the primary region of interest on the basis of our prior results. Results: The data demonstrated that the anxiety patients exhibited significantly increased activation in the bilateral STG than the normal controls. The functional connectivity analysis indicated that the patient group showed significantly decreased degree of connectivity between the bilateral STG during processing Task 2 compared to Task 1 (t = 2.588, p = 0.029). In addition, a significantly decreased connectivity was also observed in the patient group compared to the control group during processing Task 2 (t = 2.810, p = 0.012). Conclusion: Anxiety patients may exhibit increased activity of the STG but decreased functional connectivity between the left and right STG, which may reflect the underlying neural abnormality of anxiety disorder, and this will provide new insights into this disease.
Preload state detection for precision spindle bearings based on multi-level classification
Xiaohu Li,Yanfei Zhang,Yuechen Han,Jun Hong 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.11
In this study, a multi-level state classification method based on support vector data description (SVDD) is proposed to detect bearing preload state. Firstly, a three-category classification support vector data description algorithm is proposed to establish the three-state non-aliasing hypersphere model, which can combine the kernel principal component analysis (KPCA) and membership degree. Then, by classifying the first-level training sample model of uniform and non-uniform preload states, the second-level training sample model of non-uniform preload states is established based on SVDD algorithm. Moreover, the balanced multi-label propagation classification criterion is defined that can be used to identify the preload state level based on the training sample model. Finally, a preload state detection system is developed, which can accurately simulate uniform/non-uniform preload states for spindle bearings. The experimental results demonstrate that the proposed algorithm can effectively classify the preload states of spindle bearings with average accuracy higher than 94 %.
Xiaohu Wu,Jun Xu,Xingang Liu,Feng Shou Dong,Yanbing Wu,Ying Zhang,Yongquan Zheng 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.3
A simple, quick and reliable analytical method for the confirmation and quantification of propisochlor was developed. The propisochlor was extracted from water, soil and rice (stalks, rice and hull) matrices using acetonitrile, and cleaned up with primary secondary amine and determined by UPLC-MS/MS. The LODs of propisochlor ranged from 0.03 μg/kg to 0.12 μg/kg, while the LOQs ranged from 0.1 μg/kg to 0.4 μg/kg in different matrixes. The mean recoveries of propisochlor at three levels (0.005, 0.01 and 0.05 mg/kg) were in the range of 73.7-94.9% with intra-day relative standard deviations (RSD) of 1.1-13.9% and inter-day RSDR of 3.3-12.7%. This method is suitable for routine analysis of propisochlor under field conditions. The half-lives of propisochlor in rice stalks, water and soil were 1.7, 1.5 and 2.3 days in Hunan, 5.7, 1.0 and 1.9 days in Anhui and 4.8, 1.0 and 3.1 days in Guangxi.
Dynamic Tracking Aggregation with Transformers for RGB-T Tracking
Xiaohu Liu,Zhiyong Lei 한국정보처리학회 2023 Journal of information processing systems Vol.19 No.1
RGB-thermal (RGB-T) tracking using unmanned aerial vehicles (UAVs) involves challenges with regards tothe similarity of objects, occlusion, fast motion, and motion blur, among other issues. In this study, we proposedynamic tracking aggregation (DTA) as a unified framework to perform object detection and data association. The proposed approach obtains fused features based a transformer model and an L1-norm strategy. To link thecurrent frame with recent information, a dynamically updated embedding called dynamic tracking identification(DTID) is used to model the iterative tracking process. For object association, we designed a long short-termtracking aggregation module for dynamic feature propagation to match spatial and temporal embeddings. DTAachieved a highly competitive performance in an experimental evaluation on public benchmark datasets.
Xiaohu Su,Bingwu Wang,Zhaoyun Zhou,Zixian Li,Song Tong,Simin Chen,Nan Zhang,Su Liu,Maoyin Zhang 대한통증학회 2023 The Korean Journal of Pain Vol.36 No.1
Background: The purpose of this research was to assess the role of heparanase (HPSE)/syndecan1 (SDC1)/nerve growth factor (NGF) on cancer pain from melanoma. Methods: The influence of HPSE on the biological function of melanoma cells and cancer pain in a mouse model was evaluated. Immunohistochemical staining was used to analyze HPSE and SDC1. HPSE, NGF, and SDC1 were detected using western blot. Inflammatory factors were detected using ELISA assay. Results: HPSE promoted melanoma cell viability, proliferation, migration, invasion, and tumor growth, as well as cancer pain, while SST0001 treatment reversed the promoting effect of HPSE. HPSE up-regulated NGF, and NGF feedback promoted HPSE. High expression of NGF reversed the inhibitory effect of HPSE down-regulation on melanoma cell phenotype deterioration, including cell viability, proliferation, migration, and invasion. SST0001 down-regulated SDC1 expression. SDC1 reversed the inhibitory effect of SST0001 on cancer pain. Conclusions: The results showed that HPSE promoted melanoma development and cancer pain by interacting with NGF/SDC1. It provides new insights to better understand the role of HPSE in melanoma and also provides a new direction for cancer pain treatment.
Hole Diameter Deviation Control Method for Robotic Hole-Making System Based on Presser Foot Action
Xiaohu Zheng,Guanyao Zhang,Chao Zhou,Guoqiang Guo 한국정밀공학회 2024 International Journal of Precision Engineering and Vol.25 No.2
Robotic hole-making systems are widely used in aerospace, automotive and other fields, mainly for diverse and structurally complex parts processing tasks. However, the industrial robot automatic hole-making system is an open-chain multi-bar tandem mechanism, which is prone to quality problems such as unstable cutting process, large hole diameter deviation and hole wall surface defects when performing tasks such as hole-making. This article constructs a stiffness enhancement model for the axial and horizontal directions of the robot presser foot based on the robot end stiffness enhancement method and analyzes the impact of pressure changes on hole-making quality under the action of the presser foot. Through experimental data analysis, the aperture deviation decreased by 32.91% compared to before the pressure foot and the average height of outlet burrs decreased by 85.3%, verifying the feasibility of the method.