SSX2IP as a novel prognosis biomarker plays an important role in the development of breast cancer

Liu Xianfu,Tao Min 대한독성 유전단백체 학회 2023 Molecular & cellular toxicology Vol.19 No.3

Background SSX2IP plays a critical role in tumorigenesis and its overexpression has been found in many types of cancer, such as an associated antigen in acute myeloid leukemia and breast cancer. However, the pathophysiological role of SSX2IP in BC has not been evaluated. Objective To investigate that SSX2IP gene plays an important role in the development of breast cancer, which can be used as a diagnostic marker for breast cancer. Results SSX2IP are detected in BC in this study, the result shown that SSX2IP mRNA and protein were upregulated in both human breast cancer samples and cell lines. With the depletion of SSX2IP, the results demonstrated the BT549 cell activity, proliferation, migratory and invasive, clone formation abilities were inhibited, and the cell apoptosis increased. Conclusion These data indicated that SSX2IP promotes tumor progression in BC, include cell activity, proliferation, migratory and invasive, clone formation abilities were inhibited, and the cell apoptosis increased. This work further suggest that SSX2IP could be used to be a potential therapeutic targets in BC.

Global Fixed-time Stabilization for Chained Nonholonomic Systems via Output Feedback Control

Xiandong Chen,Xianfu Zhang 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.2

This paper studies the fixed-time output feedback stabilization problem for chained nonholonomic systems. By applying the switching control and bi-limit homogeneous techniques, it is firstly constructed two fixedtime state feedback stabilizing controllers for the considered systems. Then, a new state observer with a formalized switching law is proposed to fixed-time estimate system states, whose high-order terms are applied to get uniform convergence regardless of initial conditions and low-order terms are aimed to the exact convergence in finite time. Finally, based on the bi-limit homogeneous technique and Lyapunov stability theorem, fixed-time output feedback stabilizing controllers, one of which is discontinuous with a specific switching control law and the other is continuous, are constructed and the fixed-time output feedback stabilization of the considered systems is thus guaranteed. An example is presented to show the feasibility of the proposed control strategy.

Adaptive Event-triggered Output Feedback Control for Large-scale Nonlinear Time-delay Systems With Dead-zone Input

Weihao Pan,Xianfu Zhang,Hanfeng Li 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.7

This paper focuses on the event-triggered output feedback control problem for a class of large-scale nonlinear time-delay systems with asymmetric dead-zone input. Without knowing the precise priori knowledge of dead-zone parameters, an event-triggered output feedback control strategy is developed based on the dynamic gain design approach. It is proved by the Lyapunov analysis that all signals of the closed-loop system are globally bounded and the system states converge to a bounded region which is adjustable. Moreover, the Zeno behavior is avoided. Compared with the existing results, the considered nonlinear system allows more general growth condition, and the proposed event-triggered control strategy effectively handles dead-zone input, time delay and the more general nonlinear characteristic. Finally, an example is used to illustrate the validity of the proposed control strategy.

Sampled-data-based Event-triggered Control for Multi-agent Systems under Antagonistic Interactions

Yanan Qi,Rui Mu,Xianfu Zhang 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.8

In this paper, the leaderless consensus problem is considered for multi-agent systems under antagonistic interactions. Based on the sampled data, we propose an event-triggered mechanism to determine when the current state should be transmitted. This mechanism inherits the merits of both periodic and event-triggered transmission ways, thus reducing the energy consumption. Then, an event-triggered protocol is designed in a fully distributed manner to guarantee the consensus with the same magnitude but opposite sign. Different from the existing results, the designed protocol is implemented for a general digraph containing a spanning tree, and there is no restriction on the sampling period. Finally, the achievement of consensus and the validity of the obtained protocol are demonstrated by simulations.

Output Feedback Stabilization for a Class of Cascade Nonlinear ODEPDE Systems

Yanjie Chang,Tongjun Sun,Xianfu Zhang,Xiandong Chen 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.7

In this paper, the output feedback stabilization problem is studied for a class of cascade nonlinear ODEPDE systems. The nonlinear terms of ODE-subsystem are assumed to be bounded by a known constant multiplied by unmeasured states, and PDE-subsystem is a diffusion equation. Especially, the unstable diffusion equation is considered. Based on the low gain observer and a series of transformations, the output feedback stabilization problem is converted into designing proper gain parameters. Furthermore, the stability of the closed-loop system is analyzed by Lyapunov theorem. Finally, two numerical examples are given to demonstrate the effectiveness of the proposed control strategy.

Performance Analysis of Large CDMA Random Access Systems with Retransmission Diversity over Fading Channels

( Kai Yu ),( Yi Sun ),( Pingzhi Fan ),( Xianfu Lei ),( Lei Shu ) 한국인터넷정보학회 2010 KSII Transactions on Internet and Information Syst Vol.4 No.4

The random access systems, with retransmission diversity (RD) employment, over large random spreading code division multiple access (CDMA) channel subject to fading is investigated, under the assumption of infinite number of users and infinite spreading gain with their ratio converging to a constant. The low bound of the signal to interference and noise ratio (SINR) is shown to converge almost surely to a constant. The throughput, spectrum efficiency and energy efficiency in the dominating systems are obtained. The analytical results are confirmed by simulations. We find that in high traffic loads the throughput with fading is higher than that without. When the energy efficiency increases, the spectrum efficiency tends to two contrary values due to SNR increases or decreases. For the ordinary stable systems, the stability region is shown to shrink as the traffic increases and enlarge with RD employment.

Robust H∞ Control for Switched Nonlinear Port-controlled Hamiltonian Systems

Zi-Ming Wang,Airong Wei,Xianfu Zhang 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.8

In the paper, the robust H∞ control for switched nonlinear port-controlled Hamiltonian (SNPCH) systems with external disturbances is investigated via the multiple Lyapunov functions method. Under two cases that the SNPCH system is subject to actuator saturation (AS) and the SNPCH system is without AS, a design approach for the switching robust H∞ feedback controller is developed to attenuate the external disturbances. The sufficient conditions are established for H∞ control of the corresponding closed-loop systems based on Hamilton-Jacobi inequality techniques. Furthermore, via the Hamiltonian realization method, the obtained results are applied to solve the H∞ control for switched nonlinear affine systems with external disturbances. Finally, two numerical examples are presented to illustrate the effectiveness of the proposed H∞ control methods.

Covalent Immobilization of Arginine onto Polyacrylonitrile-Based Membrane for the Effective Separation of Oil/Water Emulsion

Xiang Shen,Peng Liu,Jiao Xu,Teng Liu,Jianjun Liu,Xianfu Shen,Shubiao Xia,Fan Wang 한국고분자학회 2018 Macromolecular Research Vol.26 No.13

Membrane technology has been accepted as a very effective approach to purify oily wastewater. However, the serious membrane fouling induced by the adsorption of oily foulants significantly hinders the development of membrane technology in treating oily wastewater. To improve the anti-fouling property and oil/ water separation efficiency of membrane, this work reports on the covalent immobilization of short-chain arginine (Arg) molecules onto polyacrylonitrile/polyacrylonitrile- co-poly(glycidyl methacrylate) (PAN/PAN-co-PGMA) blend membrane surface via a ring-opening reaction between epoxy groups and amine groups. It was found that the covalent immobilization of Arg molecules effectively increased the surface hydrophilicity of the membrane, resulting in a significant decrease of the interaction force between the foulants and the membrane surface. This typical characteristic was revealed by the pure water contact angle and the force-extension curve measurements. The Arg-immobilized membranes exhibited much higher separation efficiency against oil/water emulsions than the pristine PAN and PAN/PAN-co-PGMA membranes. Especially when the grafting amount of Arg was 157.3 μg/cm2, the oil rejection ratio of an Arg-immobilized membrane was as high as 99.2%. In addition, the flux recovery ratio of the membrane still reached 88.8%, even after two cycle filtrations of pure water and oil/water emulsion. These results indicated that the Arg-immobilized membrane may have practical applications for oil/water emulsion separation.

The Moisture Management and Drying Properties of Weft Knitted Plating Fabrics

Qing Chen,Dahua Shou,Rong Zheng,Jintu Fan,Xianfu Wan,Bailu Fu,Pibo Ma 한국섬유공학회 2020 Fibers and polymers Vol.21 No.6

The six types of weft knitted fabric in plating structure were made by cotton, polypropylene and polyester withdifferent number of filaments. The fabrics were tested by moisture management tester, vertical wicking and drying test. It wasfound that the large water absorption difference and the large filament density difference between the inner and outer side offabric could result in the better water absorption and drying ability. The fabric with polypropylene yarn (75D/48f) at innerside and cotton yarn (40 Ne) at outer side had best moisture management property evaluated by MMT. While the fabric withpolypropylene yarn (75D/48f) at the inner side and polyester yarn (75D/144f) at the outer side had highest vertical wickingand drying rate.