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      • KCI등재

        Evaluation of the Nanoparticle Dispersion and the Thermal Behaviors of Polyamide-6/Silica Composites

        Mei-Xian Li,Dasom Lee,SungWoong Choi 한국물리학회 2020 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.77 No.6

        Polyamide-6 (PA6)/silica (SiO2) composites with different sizes and concentrations of SiO2 nanoparticles were prepared via in situ anionic ring opening polymerization. An electron probe microanalyzer was used for visual examination to analyze the distribution of SiO2 nanoparticles in PA6/SiO2 composites. In addition, the thermal behavior of PA6/SiO2 composites was evaluated using thermogravimetric analysis and differential scanning calorimetry. As a result, the SiO2 nanoparticles were found to be well dispersed in the ε-caprolactam monomer with a watery viscosity. The sizes and the concentrations of the nanoparticles could affect both the polymerization and the crystallization behaviors of the composites.

      • KCI등재

        Challenges and Advances in Materials and Fabrication Technologies of Small-Diameter Vascular Grafts

        MeiXian Li,Qian‑Qi Wei,Hui‑Lin Mo,Yu Ren,Wei Zhang,Huan‑Jun Lu,정윤기 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

        The arterial occlusive disease is one of the leading causes of cardiovascular diseases, often requiring revascularization. Lack of suitable small-diameter vascular grafts (SDVGs), infection, thrombosis, and intimal hyperplasia associated with synthetic vascular grafts lead to a low success rate of SDVGs (< 6 mm) transplantation in the clinical treatment of cardiovascular diseases. The development of fabrication technology along with vascular tissue engineering and regenerative medicine technology allows biological tissue-engineered vascular grafts to become living grafts, which can integrate, remodel, and repair the host vessels as well as respond to the surrounding mechanical and biochemical stimuli. Hence, they potentially alleviate the shortage of existing vascular grafts. This paper evaluates the current advanced fabrication technologies for SDVGs, including electrospinning, molding, 3D printing, decellularization, and so on. Various characteristics of synthetic polymers and surface modification methods are also introduced. In addition, it also provides interdisciplinary insights into the future of small-diameter prostheses and discusses vital factors and perspectives for developing such prostheses in clinical applications. We propose that the performance of SDVGs can be improved by integrating various technologies in the near future.

      • KCI등재

        특집(特輯) 논문(論文): `11 춘계학술대회 우수 논문 ; PLA/CNT 복합재료의 결정화 특성 및 가수분해에 미치는 CNT 영향에 대한 연구

        이미현 ( Mei Xian Li ),김성하 ( Sung Ha Kim ),김시환 ( Si Hwan Kim ),박종규 ( Jong Kyoo Park ),이우일 ( Woo Il Lee ) 한국복합재료학회 2011 Composites research Vol.24 No.4

        환경오염이 나날이 증가함에 따라 바이오 재료에 대한 관심이 커지고 있다. 본 연구에서는 생분해성 열가소성 수지인 폴리 유산 (PLA)을 기지재료로 하고 탄소나노튜브 (CNT)를 나노 filler로 사용하여 압출 및 사출공정을 통하여 복합재료를 제작하였다. 시편의 결정화도를 변화시키기 위하여 어닐링 시간에 변화를 주어 처리하였다. PLA의 결정화 특성은 시차주사열량계 (DSC)를 통하여 평가하였고, 적당한 양의 CNT가 PLA의 결정화 속도를 향상시킨 것을 확인할 수 있었다. 그 외에 PLA/CNT 복합재료의 가수분해 속도는 순수 PLA에 비하여 빠르지만 PLA/CNT 복합재료의 결정화도가 증가함에 따라 가수분해 속도가 늦어지는 것을 확인할 수 있었다. 이것은 가수분해가 PLA/CNT의 계면에서 쉽게 일어나고 결정화도가 높아짐에 따라 분자 구조가 치밀해지기 때문인 것으로 판단 된다. As environmental pollution getting worse, biodegradable materials have been drawn more attention than ever. In this study, polylactic acid (PLA)/carbon nanotube (CNT) nanocomposites were manufactured via extrusion molding and injection molding. In order to change the crystallinity, annealing treatment was done for different time span. Crystallization kinetics of PLA was analyzed by differential scanning calorimeter (DSC), and it was confirmed that a proper amount of CNT can increase the crystallization rate of PLA. In addition, the presence of CNT significantly accelerates the hydrolytic degradation rate of PLA, however, it decreases with the increase of crystallinity. The reason is that degradation may occur in the PLA/CNT interface easily, and the molecular structure of the composite becomes dense with the increase of crystallinity.

      • KCI등재후보

        Factors that Influence the Presciption of Antipsychotics for Patients with Schizophrenia in China

        Tian-Mei Si,Liang Shu,Ke-Qing Li,Xie-He Liu,Qi-Yi Mei,Gao-Hua Wang,Pei-Shen Bai,Li-Ping Ji,Xian-Sheng Chen,Cui Ma,Jian-Guo Shi,Hong-Yan Zhang,Hong Ma,Xin Yu 대한정신약물학회 2011 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.9 No.3

        Objective: To investigate the patterns of antipsychotic use in China and to analyze the factors that influence antipsychotic prescriptions. Methods: A standardized survey was conducted from May 20 to 24 2002 in five different regions of China with varying economic levels. The patterns of antipsychotic medication use were analyzed in a sample of 4,779 patients with schizophrenia. The survey gathered information on demographic characteristics, clinical profiles, and antipsychotic medications prescribed. Multiple logistic regression was used to analyze factors related to patterns of antipsychotic medication use. Results: A plurality of patients with schizophrenia was treated with clozapine (39%); this was followed by risperidone, sulpride,chlorpromazine, perphenazine, and haloperidol. More than 56.3% of patients were treated with only one atypical antipsychotic. The mean daily dose of chlorpromazine was 365±253 mg (mean±standard deviation), and 6.5% of patients were treated with depot injections of typical antipsychotic medications. A total of 73.7% (n=3,523) of patients with schizophrenia received monotherapy,24.8% (n=1,183) received two antipsychotics, 1.1% (n=52) received three antipsychotics, and one received four different antipsychotics. Patients often simultaneously received other classes of medications including anticholinergic agents, benzodiazepines,β-blockers, antidepressants, and mood stabilizers. Economic status and clinical symptoms were the main factors that contributed to the patterns of antipsychotic prescription. Conclusion: The present study suggests that atypical antipsychotic medications, especially clozapine, are the primary psychiatric treatments of choice in the management of schizophrenia in China. Moreover, the economic status and clinical profile of the patient are the major factors affecting the prescription of antipsychotic medication.

      • KCI등재후보

        Use of Clozapine for the Treatment of Schizophrenia: Findings of the 2006 Research on the China Psychotropic Prescription Studies

        Tian-Mei Si,Yun-shu Zhang,Liang Shu,Ke-Qing Li,Xie-He Liu,Qi-Yi Mei,Gao-Hua Wang,Pei-Shen Bai,Li-Ping Ji,Xian-Sheng Cheng,Cui Ma,Jian-Guo Shi,Hong-Yan Zhang,Hong Ma,Xin Yu 대한정신약물학회 2012 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.10 No.2

        Objective: Clozapine is one of the most commonly used antipsychotic drugs in China. To date, few studies have investigated the patterns the prescription of clozapine nationwide. The present study examined these patterns in China in 2006 and identified the demographic and clinical characteristics associated with the use of clozapine. Methods: Using a standardized protocol and data collection procedure, we surveyed 5,898 patients with schizophrenia in 10provinces with differing levels of economic development. Results: Overall, clozapine had been prescribed for 31.9% (n=1,883) of the patients; however we found considerable variation among the 10 provinces. The frequency of clozapine use was highest in Sichuan (39.3%) and lowest in Beijing (17.3%). The mean daily dose of clozapine was 210.36±128.72 mg/day, and 25.1% of the patients were treated with clozapine in combination with other antipsychotics. Compared with the group not receiving clozapine, clozapine-user had been treated for longer durations and had experienced a greater number of relapses and hospitalizations. Furthermore, those in the clozapine-user had lower family incomes, were less able to seek psychiatric services, and more likely to be male and have a positive family history of schizophrenia. A multiple logistic regression analysis revealed that age, sex, professional help-seeking behaviors, duration of illness, economic status, educational level, and clinical manifestations were associated with the use of clozapine. Conclusion: Clozapine use is common in China. However, use of the antipsychotic varies among provinces, and demographic and clinical factors play important roles in the prescription of clozapine.

      • 양방향 필터와 전역적 톤 매핑 기법을 이용한 넓은 동적 영역 이미지 표현 방법

        박미선(Mei-Xian Piao),윤하경(Ha-Kyung Yoon),김신혜(Shin-Hye Kim),최지윤(Ji-Yoon Choi),이서영(Seo-Young Lee),임재영(Jae-Young Lim),조윤영(Yoon-Young Jo),박미소(Mi-so Park),정제창(Je-Chang Jeong) 대한전자공학회 2016 대한전자공학회 학술대회 Vol.2016 No.11

        넓은 동적 영역 (high dynamic range : HDR) 이미지는 다양한 분야에서 인기를 얻고 있다. HDR 컨텐츠는 실제 세계에 더 가깝고 시각적으로도 우수하다. 하지만 대부분의 디스플레이는 좁은 동적 영역 (low dynamic range : LDR) 만 지원이 가능하며, 전문적인 HDR 디스플레이의 경우에는 가격이 비싸고 기술력이 부족한 문제점이 있다. 이를 해결하기 위해서 톤 매핑 기법 (tone mapping operators : TMOs) 을 사용한 동적 영역 압축을 수행한다. 본 논문에서는 양방향 필터링 (bilateral filtering : BF) 과 전역 톤 매핑 (global tone mapping)을 이용한 신뢰도 있는 HDR 디스플레이 방법에 대하여 논하도록 한다.

      • KCI등재

        5∼6세기 중국 1탑1금당 불교사찰 배치계획의 변화특성

        홍매선(Hong, Mei-Xian),김성우(Kim, Sung-Woo) 대한건축학회 2014 대한건축학회논문집 Vol.30 No.7

        Ancient Buddhist temples in China began to be built in the 3rd century, and numerous temples were built during the Six Dynasties period (420-589 AD). The site layouts of only about five temples built between the late 5th and late 6th centuries have been identified through excavation. These temple sites have a single pagoda/image hall style and reveal a process of change over this 100-year period. This paper describes in detail how these five temple sites, despite having the same single pagoda/image hall form, show differences and changes. The underlying reasons for and significance of this process of change are also investigated. These sites demonstrate well the process by which temple layouts changed from a pagoda-centered arrangement to an image hall-centered arrangement. This development is closely connected to Korean Buddhist architectural plans during the same period.

      • KCI등재

        이상화 시에 나타난 멜랑콜리의 양상

        배선미(Pei, Xian-Mei) 한국시학회 2020 한국시학연구 Vol.- No.64

        본고에서는 피식민 국가에 살다간 시인 이상화가 인지한 비극적 현실인식을 시로 확장하는 과정에서 드러난 슬픔과 비애의 감정을 ‘멜랑콜리의 정동’이라고 규명하였고 층위를 나눠서 세밀하게 고찰하였다. 우선 이상화의 작품에 드러난 세계인식의 형성을 살펴본다면 ‘상실’이라는 체험이 위치하고 있음을 볼 수 있다. 그는 자신이 직접 경험한 상실 체험과 이로 인해 파생된 우울한 내면을 동물 이미지와 결합하여 독특한 시 세계를 형성하였다. 조국과 민족 상실을 경험한 이상화는 자신이 처한 세계를 임박한 파국으로 바라보았다. 그의 시에 나타난 신 또는 신적인 이미지는 구원자의 모습이 아니라 오히려 피할 수 없는 재앙과 종말을 가져오는 부정적인 존재로 형상화되었다. 이런 불행의 심리가 세계의 종말과 초월적 존재의 구원에 대한 불신을 바탕으로 하고 있다는 점에서 본고에서는 ‘종말론적 멜랑콜리’라고 정의하였다. 이상화는 부정적 세계의 종말에 대한 기대를 표출했지만 이는 단지 파멸의식 또는 죽음 충동으로 끝나는 것이 아니다. 파국과 같은 현실 속에서도 그는 새로 창조된 세계에 대한 희망을 간직하였으며 새로움을 추구하는 ‘영웅적 멜랑콜리’의 태도를 보여주었다. 이러한 분석을 통하여 이상화 시에 나타난 멜랑콜리는 단순한 슬픔만으로 귀결된 것이 아니라 상실한 것을 인식하고 그 상실한 것을 새롭게 창조하게 하는 긍정적인 기능을 수행한다는 것을 확인할 수 있었다. 이상화의 멜랑콜리는 역동적인 힘이 내포되어 있으며 이는 시 세계를 추동하는 원동력으로 작동한다. 그리하여 ‘멜랑콜리’는 그동안 감상주의 또는 퇴폐주의로 평가받았던 이상화의 시 세계를 재평가할 수 있는 계기를 마련해 준다. This paper mainly does research about a poet Lee Sang-hwa who has lived in a colonized country and his sadness he showed in his poem in the process of his cognition of the real world. And the feelings, which can be summarized as “melancholy affect”, will be investigated in layers subtly. By combining his experience of losing and the crying of animals together, Lee Sang-hwa expressed his sadness and sorrow over Japanese imperial aggression and extended sadness of his and the community. Besides, Lee Sang-hwa, who experienced the losing of his motherland and nation, believed that the world in which he lived was on the verge of collapse. The image of god in his poems didn’t mean the savior, but the brining inevitable disasters to the public of Korea oppositely. Therefore, a defiant attitude against the god was shown. Such a mentality, based on the expectation of the end of the world and the distrust of salvation, is defined as “the eschatological melancholy”. Despite of his expectation of the end of the passive world where he lived, this didn’t just end by the consciousness of destruction or the impulse of death. In the reality just as a dangerous situation, he was still hopeful about the “new world”, and put constant emphasis on innovation, which has demonstrated the “melancholia heroica”. In conclusion, the melancholy embodied in Lee Sang-hwa’s poems is not merely negative emotion, but an affect that implies a force driving him move forward. This is of great significance when re-examining his world of poetry.

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