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A case of nevus spilus with congenital melanocytic nevus
( Wonjoo Kwon ),( Yosup Shin ),( Eunbyul Cho ),( Eunjoo Park ),( Kwangho Kim ),( Kwangjoong Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1
Nevus spilus is a relatively common skin lesion characterized by multiple pigmented macules or papules within a pigmented patch. It is controversial whether NS is congenital or acquired. Congenital melanocytic nevus is defined as a cutaneous lesion appeared at birth, containing melanocytic nevus cells. It is characterized by the diffuse infiltration of melanocytes in the deepest reticular dermis and subcutis, and by the presence of melanocytes around skin appendages. A 16-year-old female patient presented with a congenital pigmented skin lesion on the left upper arm. Speckled brownish to black colored macules with background light brown patch was noticed. Skin biopsy was performed on her left upper arm, and showed pigmentation over dermal-epidermal junction. It also showed mild elongated rete ridge over diffuse junctional nest and nevus cell of upper dermis, with proliferating melanocyte along elongated rete ridge. Nevus cells were also present around hair follicles, sweat glands and vessels in the deep dermis. Immunohistochemical staining showed melanocytes on upper dermis which is positive in HMB-45 staining and basal layer cells with positive in S-100 protein staining. Therefore, the lesion was diagnosed with a nevus spilus combined with congenital melanocytic nevus. This case presents the evidence for the congenital nature of nevus spilus. Herein, we report a case of nevus spilus with congenital melanocytic nevus.
A case of Davener`s dermatosis
( Wonjoo Kwon ),( Jimin Ha ),( Eunbyul Cho ),( Eunjoo Park ),( Kwangho Kim ),( Kwangjoong Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.1
Davener’s dermatosis is a variant of frictionhypermelanosis first described by Naimer et al. in 2000. Davener’s dermatosis is characterized by an elongated, vertical, midline, hyperpigmented patch with indistinct borders, which was distributed along the skin overlying bony protuberances of inferior thoracic and lumbar vertebrae. Repeated rubbing of the lower back against a rigid backrest in subjects with a lean body type was considered to induce changes that promote hyperpigmentation. A 30-year-old male presented several ill-defined, elongated, vertical, hyperpigmented dark brownish patches on the back. He had a 2-year history of skin lesions on the lower back which spread gradually. He did not have any medication history nor underlying disorders. Biopsy specimen from the hyperpigmented patch showed diffuse hyperkeratosis, acanthosis, elongation and fusion of rete ridges, and marked basal hyperpigmentation in epidermis. Thus we diagnosed Davener’s dermatosis and treated with Q-switched neodymium: yttrium- aluminum-garnet laser. Davener’s dermatosis has been reported rarely and only one case was reported previously in Korea. Also, reports on treatment of the disease are sparse. Herein, we reportan uncommon case of Davener’s dermatosis.