만성폐쇄성 폐질환 환자에서 적혈구 항산화효소의 변화

국기용,이만재,조희충,임영국,박일,김원식,이승일,이병래 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Toxic oxygen free radicals have been implicated as important pathologic mediators in many clinical disordesrs. Enhandng the intracellular content of antioxidant enzymes can provide means of limiting biological damage caused by oxygen free radicals. Many investigations have examined the potential of various oxyradical scavengers to modulate oxyradical injury. The oxygen free radicals play a role in the pathogenesis of chronic obstructive pulmonary disease. To investigate the pulmonary oxyradical injury and the protective role of antioxidant enzymes, author measured the amount of thiobarbituric acid reactants, the activiteies of antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase) and the sulfhydryl groups in serum and red blood cells from the chronic obstructive pulmonary disease groups and the normal controls. The thiobarbituric acid reactant in chronic obstructive pulmonary disease groups was increased than the controls in both serum and red blood cells, and the superoxide dismutase activity in red blood cells was no statistically difference in both groups. But, the glutathione peroxidase and catalase activities were lowered in chronic obstructive pulmonary disease groups than the controls. The sulfhydryl groups in serum and red blood cells were no statistically difference in both groups. These results suggest that the increased thiobarbituric acid reactant in chronic obstructive pulmonary disease groups mean oxygen radical toxicity, and the decreased glutathione peroxidase and catalase activities may play a role in cellular injury.

공주지역의 탄성파 및 전기 비저항탐사

이원국 공주대학교 사범대학 과학교육연구소 1997 과학교육연구 Vol.28 No.1

공주지역에서 탄성파 탐사를 실시하였고, 탄성파 탐사자료를 이용하여 주시곡선을 그리고 해석하였다. A측선에서 제1층의 탄성파 속도는 210 m/sec이고, 그 두께는 4.49 m이며, 제2층의 속도는 1974m/sec이다. B측선에서 제1층의 속도는 1838m/sec이고, 제2층의 속도는 1689 m/sec이다. 전기 비저항탐사에서는 웨너 전극배열법을 이용하여 각 전극 간격을 변화시키면서 측정하였다. 슐럼버져 전극배열법을 이용하여 수직단면에 따른 비저항의 변화를 측정하고 불연속면의 깊이를 추정하였다. 연구지역의 26개 지역에서 측정한 전기 비저항자료 중에서 남산지역의 것은 다음과 같이 해석된다; C지역-측점 4-27까지는 1000-2900ohm-m의 비교적 낮은 값을, 측점 -25-3까지는 2000-6000 ohm-m의 높은 값을 나타낸다. D지역-측점 1-27까지는 1000-2700 ohm-m의 비교적 낮은 값을, 측점 25-42까지는 3000-6000 ohm-m의 높은 값을 나타낸다. 일정한 범위내에서 높은 비저항 값을 보이는 경향은 지하에 매장되어 있는 유적이나 공동에 의한 것으로 해석된다. 금강 곰나루백사장의 비저항자료를 해석하면 다음과 같다; 제 1층의 비저항치는 5000 ohm-m이고, 그 두께는 1.25 m로서 건조한 사층이다. 제 2층의 비저항치는 260 ohm-m이고, 그 두께는 29 m로서 대수층으로 해석된다. 제 3층의 비저항치는 2000 ohm-m로서 안산암류로 보인다. 본지역의 암석은 편마암, 운모 편암, 화강암류, 퇴적암류, 안산암류와 충적층이다. 백악기의 퇴적암층은 각력암, 역암, 사암과 이암이다. 충적층은 비교적 두껍게 발달되어 있다. 금강분지의 충적층에는 풍부한 지하수층이 포함되어 있다. Seismic wave data measured in Kongju area was analyzed. A single channel signal enhancement seismograph and 12-channel engineering seismograph were used to acquire seismic wave data. A shock seismic wave is generated with sledge hammer, and the time required for the wave to travel different distance is measured. At the traverse A, the calculated seismic velocity and depth of the first layer are 210 m/sec and 4.49m. Seismic velocity of the second layer is 1974m/sec. At the traverse B, seismic velocity of the first layer is 1838m/sec and velocity of the second is 1638m/sec. Resistivity data of 26 points in the study area were acquired using ABEM ac terrameter and strata scout. Wener electrode configurations of different spacings is used to determine the variations of apparent resistivity in a horizontal direction. Schlumberger array is used to determine the vertical change in the resistivity of the subsurface layers and the depth to the discontinuity horizons. In the resistivity profiling of the C and D area, a high resistivity anomaly zones(2000-6000ohm-m) were detected on a certain traverce and they are interpreted to be caused by underground cavity or antient tomb site. The resistivity data in the Komnaru area is interpreted as follow; The upper unit is mainly composed of dry sand(5000ohm-m,1.25 m),the second unit is wet sandy layer(260ohm-m,29m) and the third unit is bed rock(2000ohm-m). The rocks exposed in the Kongju basin are gneiss, mica schist, granite, sedimentary rock member, andesitic rock and alluvium. A Cretaceous sedimentary rock layers consist of breccia, gravelstone, sandstone and mudstone. The alluvium layer is comparatively thick. Ground water resources are developed plentifully in the alluvial planes of Kum river basin.

Bandom Amplified Polymorphic DNAs 기법을 이용한 Bifidobacteria의 신속한 동정

왕지원,민해기,장영효,강국희 성균관대학교 생명과학자원연구소 1995 生命資源科學硏究 Vol.2 No.1

Random Amplified Polymorphic DNAs (RAPD) has been applied to the identification of human intestinal anaerobic Bifidobacteria. Recently, The RAPD technique has been used to analyse DNA polymorphism of genomic DNA from eukaryotes such as plants and animals(1, 3, 4, 10, 11). But there were only several reports on the polymorphism of prokaryotic genomic DNA by using this method(2,7). Total 100 random sequence primers were used in screening of species-specific primer. The oligonucleotide primers were ten bases long and designed to have average G+C contents of 60 mol %. Eight species of Bifidobacteria from human feces were selected. According to conventional method genornic DNA were extracted from each bifidobacterium and then RAPD-PCR was performed. Four primers have produced distinct electrophoretic band patterns, RAPD markers. Especially arbitrary primer # 101 showed species-specific DNA polymorphism for each of Bifidobacterial genomic DNA tested. The arbitrary primer # 101 showed good reproducibility when the PCR conditions were optimized. And also primer # 156, # 174, # 183, have produced amplified PCR products but not for all of the strains tested. Better DNA polymorphism was observed when two arbitrary primers were used in combination.

무기 알루미늄 염으로부터 침전법으로 제조한 알루미나 분체의 소결특성에 미치는 음이온의 영향

배원태,박민준,이국림 慶尙大學校生産技術硏究所 1994 生産技術硏究所論文集 Vol.10 No.-

In order to investigate the effects of inorganic anions(??, ??, ??) on the dispersion of aluminum hydrate precipitates in the solution, transition of precipitates, and the sinterability of alumina powders, three kinds of aluminum salts[Al₂(SO₄)₃.14H₂O, AI(NO₃)₃.14H₂O, AICI₃. 6H₂O]were used as starting materials. The dispersion power of the divalent anion was lower than monovalent anions. But the particle size of alumina powder obtained from the calcined precipitate containing divalent anion appeared smaller tnan that of the precipitates containing monovalent anions due to the difference of the transition path and the staring temperature of the consolidation of the transition aluminas. The fired densities of the specimens sintered at 1550℃ for 3hours showed 3.94g/㎤, 3.90g/㎤, and 3.88g/㎤ for Al₂(SO₄)₃.14H₂O, AI(NO₃)₃.14H₂O, and AICI₃. 6H₂O, respectively.

지구의 기초

이원국 공주대학교 과학교육연구소 2003 과학교육연구 Vol.34 No.-

지구의 모양을 유지시켜주는 지구의 기초는 지구내부 구조에 있다. 지구내부는 구성물질의 확학조성의 차이로부터 지각, 맨틀, 핵의 큰 기본 영역으로 구분된다. 지구의 점탄성 구조는 주로 고온, 고압 하에서의 지질상태의 차이를 포함하고 있다. 지구의 범탄성 구조는 암석권, 그 상부에 저속도층을 포함하는 연약권, 전이대, 하부맨틀, 외핵 및 내핵으로 되어 있다. 동일한 화학조성의 물질이라도 고온, 고압상태가 다르면 아주 다른 물리적 성질을 보인다. 온도, 압력 상태의 차이에 의한 구성물질의 이러한 상변화의 결과로 맨틀 최상부에 저점성층이 존재하고, 외핵은 유체상태이고 내핵은 고체상태를 유지한다. 하부맨틀에서 점성률의 수직적인 큰 변화율이 나타난다. 지하 1,900km에서 2,900km까지의 하부 맨틀부분은 높은 점성률과 강한 크립현상을 보여주며, 거의 탄성체에 가깝다. 따라서 이 하부맨틀 부분이 지구의 기초에 해당하는 것으로 여겨진다. 지표의 수백㎢ 이상의 대부분의 지역에서는 지각균형이 이루어지면서 지구의 지형을 유지시켜 주고, 그 이하의 좁은 지역에서는 지각물질의 탄성에 의하여 지구의 지형이 지탱된다. The foundation of the earth is in the earth's internal structure. The earth's inner structure is classified to the crust, mantle and core by its chemical compositions. The earth's elastic viscosity structure is classified to the lithosphere, asthenosphere (added low velocity zone on its top). Transition zone, lower mantle, outer core and inner core by the different physical properties according to high temperature and high pressure in the inner earth. A lower viscosity layer is on the top of upper mantle. composition with a different pressure and temperature. The large values of the radial variation in viscosity in the lower mantle are notable features. The lower mantle of a depth from 1,900km to 2,900km has so a high viscosity and strong creep that it is almost perfect elastic material. And the lower mantle seems to be a foundation of the earth. On the extensive area over some hundreds ㎢, the earth's geography is supported by the isostasy. But on a smaller area, a geography of the earth is supported by the elastic property of the earth' crust.

황토 급여가 거세한우의 발육에 미치는 영향

조원모,기광석,정하연,강수원,김준식,백봉현,김용국 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.1

본 연구는 거세한우 육성우에 대한 황토 첨가급여가 발육에 미치는 효과를 구명하고자 발육능력, 사료섭취량을 규명한 바 아래와 같은 결과를 얻었다. 전 시험기간 동안의 평균 일당증체량은 대조구와 황토급여구가 각각 0.91㎏과 0.87㎏/day로 대조구가 높은 것으로 나타났지만 유의성은 인정되지 않았다. 사료섭취량은 대조구와 황토급여구 모두 평균 일일 두당 농후사료 섭취량이 2.42㎏이었으나, 건초섭취량에 있어서는 각각 3.02와 3.14㎏으로 황토급여구가 다소 높은 경향으로 나타났다. The study was conducted to investigate the effect of dietary supplements of reddish clay on the growth performance in growing Hanwoo steers. A total of 8 calves was allocated into 2 feeding groups, control(basal diet) and treatment(basal diet plus ad libitim Reddish clay) for Hanwoo steers. This study was carried out for 5 months with a total of 8 calves. The results obtained in the present studies are summarized as follows : Average daily gains throughout the experimental period of 4 months to 9 months of age were 0.91 and 0.87㎏ for control group and reddish clay-supplemented group, respectively, however, no statistical significances were found. Average daily intake of concentrates was 2.42㎏ for each group, while that of hay tended to be higher in reddish clay-supplemented group(3.14㎏) than in control group(3.02㎏).

堆積地層에서의 彈性波 探査와 解析

李元國 공주대학교 사범대학 과학교육연구소 1980 과학교육연구 Vol.12 No.1

By the time-distance curve for the case, of two media with respective velocities of Vo and V₁, separated by a horizontal discontinuity at depth Zo, the depth Zo to the interface can be calculated from the intercept time or from the crossover distance; ?? (1) or ?? (2) In the three media case, the depth Z to the lower interface is the sum of Z₁ and Zo. In this case, the depth Z₁ can be calculated by the following equation; ?? (3) Thus, in the point S-1, the calculated depth and the velocity of the first layer is about 2.56m and 350m/sec. The depth and the velocity of the second layer is about 3.74m and 1150m/sec. The velocity of the third layer is about 1800m/sec. The first layer is consist of alluvium, the second and the third layers are consist of andesite. In the point S-2, the calculated depth and the velocity of the first layer is about 2.6m and 400m/sec. The depth and the velocity of the second layer is about 3.67m and 1175m/sec. The velocity of the third layer is about 2475m/sec. The first layer is consist of alluvium, the second and the third layers are consist of andesite.

炭酸鹽 鑛物과 長石의 着色方法

李元國 공주대학교 사범대학 과학교육연구소 1976 과학교육연구 Vol.8 No.1

Many stains have been developed to identify carbonate minerals and feldaspar. Alizarin red's is the most effective stain for calcite, from which the dolomitization or dedolomitization of carbonate rocks can be distinguished. by the length of the staining time, the composition of carbonates can be known.

응급센터에서 기관내 삽관을 시행하지 않은 호흡곤란 환자의 동맥혈 이산화탄소분압과 호기말 이산화탄소분압의 연관성분석

김형국,박승현,오동렬,박규남,이원재,황두영,최승필,이운정,정시경,김세경 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Background: The end-tidal carbon dioxide tension(ETCO₂) is defined as a partial pressure of carbon dioxide at the end of an exhaled breath. The purpose of this study is to determine the correlation between ETCO₂and arterial carbon dioxide tension(PaO₂) in nonintubated patients with respiratory distress in emergency department(ED). Methods: A prospective non-blind study was performed in ED of our university hospitals. Participants included all nonintubated adult patients with respiratory distress requiring arterial blood gas analysis. ETCO₂was measured with a capnography monitor during tidal volume breathing. ETCO₂were recoreded at the time of arterial blood gas sampling. The correlation between ETCO₂and PaCO₂was analyzed in all patients and in subgroups by simple linear regression. Results: Sixty patients were enrolled. In all patients, ETCO₂was 5.72mmHg lower than PaCO₂and correlated well with PaCO₂(r²=0.716). ETCO₂correlated best with PaCO₂in patients who were either acidotic or non-smoking. Conclusion: ETCO₂correlate well with PaCO₂in nonintubated patients with respiratory distress in ED. ETCO₂may be sufficient to reflect PaCO₂in selected patients and obviate the need for repeat arterial blood gas determination.

컴퓨터과학 교육을 중심으로 한 중등 컴퓨팅 교육과정 설계

신상국,권대용,김형신,염용철,유승욱,이원규 한국컴퓨터교육학회 2005 컴퓨터교육학회 논문지 Vol.8 No.3