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박원혁 釜山大學校 師範大學 2003 교사교육연구 Vol.42 No.-
제초제인 Gramoxone이 고추 생육에 미치는 생리적 기능을 구명하기 위하여 고추잎에 Gramoxone을 농도별(1.0, 10, 20 및 50 ppm)로 처리하여 광합성 색소, 환원당 및 광계에 미치는 효과를 조사하였다. 광합성 색소에 미치는 효과는 1.0, 10, 20 및 50 ppm 개체군에서 생체 l g당 엽록소 함량이 대조군에 비하여 각각 79.97, 80.60, 80.96 및 84.11%까지 감소하였으며 carotenoid함량은 36.15, 43.11, 44.72 및 45.25% 까지 각각 감소하였다. 환원당 함량은 1.0, 10, 20 및 50 ppm 처리군에서는 대조군에 비하여 19.15, 29.26, 34.58 및 55.32%까지 감소하였다. Gramoxone 처리에 의하여 광계 (H₂O→FeCy+NH₄Cl)활성이 저해되었고, 특히 50 ppm Gramoxone 처리군에서는89.9%까지 저해를 받았다. 따라서 Gramxone은 광합성 색소 파괴 및 합성 억제, 환원당 합성 저해 및 광계의 활성 저해를 일으키므로 고추의 생장에 크게 영향을 미치는 것으로 사료된다.
이승원,김장욱,박영진,송태현,이병돈,장혁순 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1
The fungal sinusitis is relatively rare and mainly develops in immunocompromised hosts, but is sporadically appears in the immunocompetent patients, where its incidence tends to be increasing. Because the clinical features of this disease are similar to those of chronic suppurative sinusitis, this entity may be overlooked. We analysed thirteen fungal sinusitis from January 1997 through December 1999 based on clinical features, laboratory characteristics and operative findings. The results are as follows. 1)Fungal sinusitis occurred 3.3 times as frequently in female patients as in male patients and the peak age groups are 4th and 5th decades. 2) The time intervals between the onset of symptoms and the first hospital visit were as follows: 5 cases within 3 months, 1 case between 4 and 6 months, 3 cases between 7 and 12 months, and 4 cases over 1 year. 3) The chief complaints were nasal obstruction, postnasal drip, rhinorrhea, cheek pain, headache, ocular pain, sneezing. 4) The characteristic computerized tomographic findings were hyperattenuated lesions in the maxillary sinus and in the nasal cavity near the natural ostium. 5) The most common pathogen was Aspergillus(92.3%) 6) We performed Caldwell-Luc's operation only in 4 cases, Caldwell-Luc's operation with intranasal ethmoidectomy in 3 cases, Caldwell-Luc's operation with endoscopic sinus surgery in 3 cases and endoscopic sinus sugery only in 3 cases. 7) Most of the gross specimens revealed a fungus ball containing a black-brown necrotic debris or caseous material.
신부전이 동반된 당뇨병 환자에서 발생된 침습성 모균증 : 수술과 Liposomal amphotericin B 및 GM-CSF 병합 요법에 의한 성공적인 치험 1예
이원영,오기원,임국희,장재혁,이동건,최정현,강무일,신완식,차봉연,이광우,손호영,강성구 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.4
저자들은 신부전이 동반된 당뇨병 환자에서 발생된 부비동형 모균증에 대하여 수술과 함께 liposomal amphotericin B 및 GM-CSF의 복합치료를 하여 성공적으로 치료한 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Mucormycosis (zygomycosis) primarily affects diabetic or immunocompromised patients and typically progresses rapidly, necessitating surgical excision and antifungal therapy with amphotericin B. Large doses of amphotericin B are needed for cure, but it has the risk of causing significant renal toxicity. The recent development of liposomal amphotericin B allows antifungal therapy to be administered with potentially improved efficacy and reduced nephrotoxicity. We have experienced a case of paranasal mucormycosis successfully treated with surgery, liposomal amphotericin B and GM-CSF. A 59-year-old male suffering from diabetes mellitus for 6 years was admitted with pain at left maxillary area. He was diagnosed as mucormycosis after cytologic exam on the necrotic nasal mucosa, which showed typical hyphae. He have had diabetic nephropathy with macroproteinuria and had rapidly rising serum creatinine levels with the amphotericin B treatment: creatinine levels reverted to basal level with the use of liposomal amphotericin B. Despite surgical excision and continued antifungal therapy, his infection was not effectively controlled. Therefore, GM-CSF was administered additionally to improve phagocytic activity of leukocytes. He was finally cured after receiving a combination of aggressive surgery, liposomal amphotericin B and GM-CSF. To our knowledge, this is the first detailed clinical description of the treatment of mucormycosis with liposomal amphotericin B in Korea.
구속된 비행 청소년들의 석방 후 6개월 이내 재범의 예측요인
서동혁,정선주,손창호,김원식,고승희,함봉진,조성진,김영기,이중재 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.3
연구목적 : 본 연구는 범법행위로 인해 검참에 구속된 청소년들의 6개월 이내 재범여부를 예측할 수 있는 요인을 분석함으로써 재범의 가능성이 높은 청소년들을 조기에 선별하여 적절한 중재를 시행하기 위한 목적으로 시행되었다. 방 법 : 검찰에 구속된 후 교도소나 소년원에 수감되지 않고 석박된 남자 청소년 125명을 대상으로 하였다. 범죄기록 검토를 통해 사회인구학적, 범죄관련 변인들에 대해 조사하였고, 가족환경 및 부모양육태도, 정신병리, 성격장애, 도덕발달수준 등과 연관된 변인을 알아보기 위해, 부모-이동 갈등해결척도(CTSPC), 한국판 가정환경척도(FES), 한국형 부모양육행동척도, 간이정신진단검사(SCL-90-R), Beck 우울증척도, Beck 불안 척도, 한국판 청소년용 도덕발달수준 평가도구와 한국판 성격장애검사(PDQ-R)를 시행하였다. 결 과 : 전체 연구대상 125명 중 55명 (44%)이 석방 후 6개월 이내에 1회 이상의 재범을 행하였다. 재범군은 비재범군에 비해 구속당시 나이가 어리고, 신체적 학대력이 높았으며, 도덕발달수준이 낮고, SCL-90-R의 적대감척도점수가 높으며 PDQ-R의 반사회적 인격장애에 해당되는 경우가 많았다. 두 집단간 가족환경이나 부모양육태도에는 유의한 차이가 나타나지 않았다. 재범군은 폭력범죄로 구속된 경우가 비재범군에 비해 적었고 첫 범죄시 연령이 어리고 전과가 있는 경우가 많았다. 로지스틱 회귀분석 결과, 재범에 대한 예측요인으로 첫 범죄당시 연령(오즈비=2.91), 반사회적 성격장애(오즈비=2.85), 신체적 학대력(오즈비=2.65)의 세 변인이 포함되었으며, 재범여부에 대한 판별력은 72.8%로 나타났다. 결 론 : 본 연구결과 구속된 청소년들의 재범률이 매우 높다는 사실과 범죄행위에 가담한 연령이 어릴수록, 반사회적 성격장애가 있고 성장과정 중 부모로부터 학대를 받은 경험이 있을수록 반복적인 범죄를 저지를 위험도가 높다는 것을 알 수 있었다. 향후 비행 청소년들의 재범을 예방하기 위해서는 이러한 특성을 가진 고위험군에 대한 조기개입 및 적응을 돕기 위한 프로그램의 개발이 중요할 것으로 사료된다. Objectives : This study was performed to investigate the factors predicting recidivism within 6months after release in arrested juvenile delinquents for proper screening and intervention of high-risk-subjects. Methods : The subjects consisted of 125 arrested male adolescents who were released after legal procedure in prosecutor office and court. The socio-demographic and crime-related characteristics. Were evaluated by police records, and the familial, psychopathology and personality characteristics, and the level of moral development measured by the Conflict Tactics Scale(CTS), Family Environment Scale(FES), Parental Behavioral Inventory, Symptom Checklist-90-Revised(SCL-90-R), Beck Depression Inventory, Beck Anxiety Inventory, Korean form of Moral Developmental Inventory for adolescents, and Personality Disorder Questionnaire-Revised(PDQ-R). Results : The recidivism rate within 6 months after release was 44% of the initial sample, Recidivists were younger and had higher scores on Anger-hostility scale of SCL-90-R and lower principle morality score than nonrecidivists. More recidivists had history of physical abuse and antisocial personality disorder on PDQ-R than nonrecidivists. They also showed the crime-related characteristics of lower percent of violence crime, higher incidence of previous conviction, younger age of the first crime. Among those variables, logistic regression showed that age of first crime, antisocial personality disorder, and history of physical abuse best predicted the recidivism within 6months after release. Conclusion : These results of present study suggest that the recidivism rate of arrested male adolescents is very high, and the age of first crime, antisocial personality disorder and history of physical abuse were key factors predicting recidivism. To prevent repeated crime of delinquent adolescents, the development of programs for those high-risk groups to help rehabilitation and adaptation in community would be essentil.
박원혁,정미선 부산대학교 사범대학 과학교육연구소 1998 科學敎育硏究報 Vol.25 No.-
According to the analysis of the emphasis of the theme, for each grade, variety and singularity, continuity of heredity, life and environment, and structure and function are most smoothly connected but regulation and homeostasis are badly connected in the emphasis of theme. In the emphasis of level, tissue and organ, and individuality are well connected but molecule is badly connected. In the emphasis of living thing, animal and plant are smoothly connected but protozoa is badly connected. In the emphasis of the each basic concept, all concepts are kept well but variety of living thing between middle and high school is badly connected. The connection of biology curriculum is well kept for each grade in general but each grade has a little discrepancy.
허진,최원혁,조진혁,함영희,홍정범,정성규,김현,허동 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2
Two men were admitted to hospital with flank pain, hematuria, which was diagnosised as ureteral stone. Elevation of aspartate aminotransferase (AST) without typical pattern of toxic hepatitis was observed. Careful history taking, several laboratory tests, abdominal and pelvis computered tomography was done. Findings from theses examinations supported the clinical diagnosis of ureteral stone complicated of exercised induced rabdomyolysis. Early recognization of rhabdomyolysis in clinical setting is important, because clinical manifestations have ranged from asymtomatic elevation of creatine kinase to acute renal failure which is a life threating medical emergency. Authors report two cases of exercised induced rhabdomyolysis initially admittied as ureteral stone managed with hydration
이병돈,강주원,장혁순,박철규,김장묵 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.1
Tonsillar tuberculosis, almost always secondary to pulmonary tuberculosis is very rare disease in otolaryngologic fields. Authors have experienced a case of tonsillar tuberculosis associated with miliary pulmonary tuberculosis. The patient had cough, sputum and sore throat for 1 month. On physical examinations, palatine tonsils were slightly hypertrophied, smoothly surfaced, but crypt ulceration or patches were not seen. Diffuse discrete nodules were seen in both lung fields by simple chest X-ray. In high resolution computed tomography, miliary tuberculosis was suspected and in pleural needle biopsy, granulomatous inflammaiton was diagnosed as tuberculosis. AFB smear of sputum was two positive. Histopatholoigic finding of right tonsil was consistent with tuberculosis. He was cured of it with antituberculosis medications for one year. We report the case with review of the literatures.
초·중등 및 대학교재 중 생물영역의 연계성 연구 : 물질대사에 대한 내용 중심 Emphasizing the contents of metabolism
양숙현,박원혁 부산대학교 사범대학 과학교육연구소 2001 科學敎育硏究報 Vol.28 No.-
The purpose of this study is to analyze the connection of contents about metabolism contained in the biology textbooks from elementary school to college. For this purpose, the six subjects(photosynthesis, digestion, circulation, respiration, excretion, biological energy) of biological contents were selected from textbooks. 1. The contents about metabolism was classified according to six main subjects based on biology Ⅱ textbook. They were analyzed in terms of published section parts, learning objectives and contents from the view of each school unit. 2. 6(100%) of 6 subjects were introduced at the level of elementary school. 3. Connection from elementary school to middle school was C type(100%), that from middle school to high school showed B(50%) and C(50%). Connection from high school to college was analyzed as 17 and 83% for B. C type, respectively. 4. Considering theses results about connection of the biology sphere among school units, new concept diagrams were proposed.
홍정욱,박원혁 부산대학교 사범대학 과학교육연구소 2003 科學敎育硏究報 Vol.30 No.-
The purpose of this research is to examine the conditions, the utilizations and awareness of eco-educational spots that are the fittest to children. The findings of survey carried out to 648 of children(the 4th grade 262, the 6th grade 386) are as follows: The 4th graders(96%) and 6th graders(97%) replied that the environment has been polluted or seriously polluted. and that water pollution has been the highest, TV has been selected as the most common means to get various environmental informations. The 4th graders were taught the environmental education through ethics, society, science in order. while the 6th graders ethics, science, society in order The 4th graders, expect to get environmental education through ethics, optional time (or special activity time) and society in order. For the 6th graders, on the other hand, it has been ethics, optional time (or special activity time), science in order. The survey showed that the environmental education at field had been more effective than that in classroom The students have selected a pond, a flower bed, a garden, a zoo and a vegetable garden for the environment education Main inconveniences that respondents undergo in utilizing eco- educational spots have been a long-time round trip and strict control by persons in charge. Besides, the 4th graders have complained of lack in various lives, the 6th graders of lack in sufficient learning opportunities due to a lot of participants. The respondents(81.4%) have revealed their will to put environmental conservation in practice, and the 6th graders have been more positive in searching for concrete ways of environmental conservation than the 4th graders. And they have preferred eco-educational spots that living thing inhabit to no-life spots.