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      • ADPRT Val762Ala and XRCC1 Arg194Trp Polymorphisms and Risk of Gastric Cancer in Sichuan of China

        Wen, Yuan-Yuan,Pan, Xiong-Fei,Loh, Marie,Tian, Zhi,Yang, Shu-Juan,Lv, Si-Han,Huang, Wen-Zhi,Huang, He,Xie, Yao,Soong, Richie,Yang, Chun-Xia Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

        Objective: Gastric cancer remains a major health problem in China. We hypothesized that XRCC1 Arg194Trp and ADPRT Val762Ala may be associated with risk. Methods: We designed a multicenter 1:1 matched case-control study of 307 pairs of gastric cancers and controls between October 2010 and August 2011. XRCC1 Arg194Trp and ADPRT Val762Ala were sequenced, and demographic data as well as lifestyle factors were collected using a self-designed questionnaire. Results: Individuals carrying XRCC1 Trp/Trp or Arg/Trp variant genotype had a significantly increased risk of gastric cancer (OR, 1.718; 95% CI, 1.190-2.479), while the OR for ADPRT Val762Ala variant genotype (Ala/Ala or Val/Ala) was 1.175 (95% CI, 0.796-1.737). No gene-gene or gene-environment interactions were found. In addition, family history of cancer and drinkers proportion were higher among cases than among controls (P<0.05). Conclusions: XRCC1 194 Arg/Trp or Trp/Trp genotype, family history of cancer, and drinking are suspected risk factors of gastric cancer from our study. Our findings may offer insight into further similar large gene-environment and gene-gene studies in this region.

      • SCIESCOPUSKCI등재

        FINITE LOGARITHMIC ORDER SOLUTIONS OF LINEAR q-DIFFERENCE EQUATIONS

        Wen, Zhi-Tao Korean Mathematical Society 2014 대한수학회보 Vol.51 No.1

        During the last decade, several papers have focused on linear q-difference equations of the form ${\sum}^n_{j=0}a_j(z)f(q^jz)=a_{n+1}(z)$ with entire or meromorphic coefficients. A tool for studying these equations is a q-difference analogue of the lemma on the logarithmic derivative, valid for meromorphic functions of finite logarithmic order ${\rho}_{log}$. It is shown, under certain assumptions, that ${\rho}_{log}(f)$ = max${{\rho}_{log}(a_j)}$ + 1. Moreover, it is illustrated that a q-Casorati determinant plays a similar role in the theory of linear q-difference equations as a Wronskian determinant in the theory of linear differential equations. As a consequence of the main results, it follows that the q-gamma function and the q-exponential functions all have logarithmic order two.

      • KCI등재

        FINITE LOGARITHMIC ORDER SOLUTIONS OF LINEAR q-DIFFERENCE EQUATIONS

        Zhi-Tao Wen 대한수학회 2014 대한수학회보 Vol.51 No.1

        During the last decade, several papers have focused on linear q-difference equations of the form n X j=0 aj (z)f(qjz) = an+1(z) with entire or meromorphic coefficients. A tool for studying these equations is a q-difference analogue of the lemma on the logarithmic derivative, valid for meromorphic functions of finite logarithmic order log. It is shown, under certain assumptions, that log(f) = max{log(aj )} + 1. Moreover, it is illustrated that a q-Casorati determinant plays a similar role in the theory of linear q-difference equations as a Wronskian determinant in the theory of linear differential equations. As a consequence of the main results, it follows that the q-gamma function and the q-exponential functions all have logarithmic order two.

      • KCI등재후보
      • KCI등재

        Simultaneous Information and Power Transfer for Multi-antenna Primary-Secondary Cooperation in Cognitive Radio Networks

        Zhi Hui Liu,Wen Jun Xu,Sheng Yu Li,Cheng Zhi Long,Jia Ru Lin 한국전자통신연구원 2016 ETRI Journal Vol.38 No.5

        In this paper, cognitive radio and simultaneous wireless information and power transfer (SWIPT) are effectively combined to design a spectrum-efficient and energy-efficient transmission paradigm. Specifically, a novel SWIPT-based primary-secondary cooperation model is proposed to increase the transmission rate of energy/spectrum constrained users. In the proposed model, a multi-antenna secondary user conducts simultaneous energy harvesting and information forwarding by means of power splitting (PS), and tries to maximize its own transmission rate under the premise of successfully assisting the data delivery of the primary user. After the problem formulation, joint power splitting and beamforming optimization algorithms for decode-and-forward and amplify-and-forward modes are presented, in which we obtain the optimal PS factor and beamforming vectors using a golden search method and dual methods. Simulation results show that the proposed SWIPTbased primary-secondary cooperation schemes can obtain a much higher level of performance than that of non-SWIPT cooperation and non-cooperation schemes.

      • KCI등재

        Crack tip shielding and anti-shielding effects of parallel cracks for a superconductor slab under an electromagnetic force

        Zhi-Wen Gao,이강용,You-He Zhou 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.2

        In this letter, the shielding or anti-shielding effect is firstly applied to obtain the behavior of two parallel cracks in a two-dimensional type-II superconducting under electromagnetic force. Fracture analysis is performed by the finite element method and the magnetic behavior of superconductor is described by the critical state Bean model. The stress intensity factors at the crack tips can be obtained and discussed for decreasing field after zero-field cooling. The shielding or anti-shielding effect at the crack tips depend on the distance between two parallel cracks and the crack length. The results indicate that the shielding effects of the two parallel cracks increase when the distance between the two parallel cracks decreases. It can be also obtained that the superconductors with shorter cracks has more remarkable shielding effect than those with longer cracks.

      • KCI등재

        The horizontal stability of an FLNG with different turret locations

        Zhi-Tian Xie,Jian-Min Yang,Zhi-Qiang Hu,Wen-Hua Zhao,Jing-Rui Zhao 대한조선학회 2015 International Journal of Naval Architecture and Oc Vol.7 No.2

        The horizontal stability of a Single-Point Moored (SPM) Floating Liquefied Natural Gas (FLNG) facility is investigated. Both numerical and experimental studies have been conducted for this SPM FLNG. The numerical simulations feature well the experimental data. The effects of the turret locations are studied based on the validated numerical model. Statistic results of the vessel’s motions with different turret locations are conducted and compared. The results show that the longitudinal location of the turret has a significant influence on the horizontal stability, which has a strong relationship with the yaw and roll motions. The calculated top tensions on the hawsers also develop a regular change as changing the turret’s location. The investigation will provide a brief of principles with more details for the design of the ongoing project.

      • Quality of Life for Patients with Esophageal/Gastric Cardia Precursor Lesions or Cancer: A One-year Prospective Study

        Wen, Ying,Pan, Xiong-Fei,Huang, Wen-Zhi,Zhao, Zhi-Mei,Wei, Wen-Qiang,Chen, Feng,Lan, Hui,Huang, He,Yang, Chun-Xia,Qiao, You-Lin Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1

        Background: The current study examined health-related quality of life (QoL) for patients with esophageal/gastric cardia precursor lesions or cancer before and after treatment to facilitate improved prevention and treatment. Materials and Methods: Patients with different stages of esophageal/gastric cardia lesions completed two QoL questionnaires, EORTC QLQ-C30 and supplemental QLQ-OES 18, before primary treatment, and at 1, 6 and 12 months after treatment. Results: Fifty-nine patients with precursor lesions, 57 with early stage cancer, and 43 with advanced cancer responded to our survey. Patients with precursor lesions or early stage cancer reported better QoL overall than those with advanced cancer before treatment (p<0.01). Global QoL scores before treatment and at 1 month after treatment were $71{\pm}9$ versus $69{\pm}9$ (p>0.01), $71{\pm}8$ versus $61{\pm}11$ (p<0.01), $67{\pm}11$ versus $62{\pm}9$ (p<0.01) for three stages of lesions. At 6 months after treatment, some QoL measures recovered gradually in precursor lesion and early cancer patients, while some continuously deteriorated in advanced cancer patients. At 12 months, all QoL scores were comparable to baseline for patients with precursor lesions (p>0.01), while global QoL, social, pain, and insomnia scores for early stage and advanced cancer were inferior to corresponding baseline levels (difference between means>5, p<0.01). At this time point, compared with patients with early stage cancer, those with advanced cancer showed worse QoL with all function and most symptom measures (p<0.01). Conclusions: Patients with precursor lesions or early stage esophageal/gastric cardia cancer show better QoL than those with advanced cancer. This indicates that screening, early diagnosis and treatment may improve the QoL for esophageal/gastric cardia cancer patients. Target intervention and counseling should be given by health care providers during treatment and follow-up to facilitate QoL improvement.

      • KCI등재

        Random vibration analysis of train-slab track-bridge coupling system under earthquakes

        Zhi-ping Zeng,Xian-feng He,Yan-gang Zhao,Zhi-wu Yu,Ling-kun Chen,Wen-tao Xu,Ping Lou 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.54 No.5

        This study aimed to investigate the random vibration characteristic of train-slab track-bridge interaction system subjected to both track irregularities and earthquakes by use of pseudo-excitation method (PEM). Each vehicle subsystem was modeled by multibody dynamics. A three-dimensional rail-slabgirder-pier finite element model was created to simulate slab track and bridge subsystem. The equations of motion for the entire system were established based on the constraint condition of no jump between wheel and rail. The random load vectors of equations of motion were formulated by transforming track irregularities and seismic accelerations into a series of deterministic pseudo-excitations according to their respective power spectral density (PSD) functions by means of PEM. The time-dependent PSDs of random vibration responses of the system were obtained by step-by-step integration method, and the corresponding extreme values were estimated based on the first-passage failure criterion. As a case study, an ICE3 high-speed train passing a fifteen-span simply supported girder bridge simultaneously excited by track irregularities and earthquakes is presented. The evaluated extreme values and the PSD characteristic of the random vibration responses of bridge and train are analyzed, and the influences of train speed and track irregularities (without earthquakes) on the random vibration characteristic of bridge and train are discussed.

      • KCI등재

        Design of Micro Biopsy Device for Wireless Autonomous Endoscope

        Wen-Wen Chen,Guo-Zheng Yan,Hua Liu,Ping-Ping Jiang,Zhi-Wu Wang 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.

        Well-established technology that provides assistance from outside the patient may soon give way to alternative approaches that bythe wireless robotic mechanisms inside the patient through natural orifices. For this study, two kinds of micro biopsy mechanisms weredeveloped for capsule endoscope which could traverse the gut environment automatically. This mobility allows the biopsy device tomove to the area of interest to sample specific tissues. Based on the medical and mechanism considerations, we concerned on designprecise biopsy jaw with sufficient cutting force, and the biopsy process should be safe, repeatable and visible. The lead-screw linkagesystem that actuated jaw of biopsy allowing for large force production. Using one micro-motor, the biopsy process was carried outquickly by three motions: stretching to sampling point; bite and cutting off; withdrawing into capsule body with the sample. With thecontrol and vision system, the biopsy process could compete automatically. The robot was capable of traversing in the gut environmentwirelessly and had been successfully used to biopsy gut tissue in vitro. In addition, experimental analysis of the biopsy mechanismshowed good results towards more elaborate tissue manipulation in the future.

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