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      • KCI등재

        Carbon black sintering effects on the composition of multiphase calcium phosphate bioceramics

        Wen-Cheng Chen,Chien-Ping Ju,Wen-Hsien Cheng,Jiin-Huey Chern Lin 한양대학교 세라믹연구소 2013 Journal of Ceramic Processing Research Vol.14 No.3

        The presence of carbonate (CO3 2-) combined with calcium phosphates has been believed to increase the susceptibility of natural bone formation. This study was carried out to investigate the thermal properties of apatite in nano scale precipitates with added carbon black that could act as a sintering inhibitor and a carbonate preserver. In addition, the present study aimed to determine the effects of those additives and analyze their chemical compositions. Ceramics processed at different heating temperatures were compared and characterized. The results showed that a multiphase ceramic of apatite-calcium carbonate (CaCO3)-calcium oxide (CaO) was formed in a temperature range of 600 to 800 ο C. By observing the morphologies of the ceramics, the addition of carbon black which acts as a carbonate supplier in the heating processes and further as an inhibitor to prevent the sintering effect of the nano scale particles in sub-micro range efficiently at 1400 ο C were established.

      • Research on Decoupling and Driving Factors of Industrial Ecosystem in Jiangsu Province

        Wen-wen Li,Wen-ping Wang,Tian-tian Zhou,Ying-bo Qin 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10

        Industrial sectors have resulted in a large amount of pollution. Environmental degradation problem requires more indepth research on relationships between different sectors’ economic output and pollutant emissions. This paper analyzes the relationship between industrial economy and ecology. On the basis of it, the driving factors of industrial sectors’ pollution emissions are analyzed. Firstly, decoupling elasticity of industrial sectors in Jiangsu province during 2004-2013 is analyzed by Tapio decoupling model. And then, the industrial sectors are classified into three types according to the different decoupling elasticity. Finally, the three types of industrial sectors’ driving factors of industrial solid waste output are decomposed by LMDI method. The results show that: industrial sectors in Jiangsu province are divided into strong decoupling sectors, weak decoupling sectors and expansive negative decoupling sectors; economic development significantly promotes the increase of industrial solid waste output of all sectors; technology improvement and industrial structure largely decrease industrial solid waste output of strong decoupling sectors and weak decoupling sectors; however, technology improvement accelerates industrial solid waste output of expansive negative decoupling sectors; the role of industrial structure factor changes from restraint to promotion of expansive negative decoupling sectors.

      • SCIESCOPUSKCI등재

        Evaluation of Liver Metastases Using Contrast-Enhanced Ultrasound: Enhancement Patterns and Influencing Factors

        ( Wen Tao Kong ),( Zheng Biao Ji ),( Wen Ping Wang ),( Hao Cai ),( Bei Jian Huang ),( Hong Ding ) 대한소화기학회 2016 Gut and Liver Vol.10 No.2

        Background/Aims: To evaluate the enhancement patterns of liver metastases and their influencing factors using dynamic contrast-enhanced ultrasound (CEUS). Methods: A total of 240 patients (139 male and 101 female; 58.5±11.2 years of age) diagnosed with liver metastases in our hospital were enrolled in this study to evaluate tumor characteristics using CEUS. A comparison of enhancement patterns with tumor size and primary tumor type was performed using the chi-square test. The differences between quantitative variables were evaluated with the independent-sample t-test and one-way analysis of variance. Results: The enhancement patterns of liver metastases on CEUS were categorized as diffuse homogeneous hyperenhancement (133/240, 55.4%), rim-like hyperenhancement (80/240, 33.3%), heterogeneous hyperenhancement (10/240, 4.2%), and isoenhancement (17/240, 7.1%). There were significant differences in the enhancement patterns during the arterial phase based on the nodule size (p=0.001). A total of 231 of the nodules showed complete washout during the portal phase, and 237 nodules were hypoenhanced during the delayed phase. The washout time was correlated with tumor vascularity, with a longer washout time observed in hypervascular metastases compared to hypovascular metastases (p=0.033). Conclusions: Diffuse homogeneous hyperenhancement followed by rapid washout was the most common enhancement pattern of liver metastases on CEUS and was affected by the nodule size and tumor vascularity. Small metastases were prone to show diffuse homogeneous hyperenhancement. Hypervascular metastases showed a significantly longer washout time compared to hypovascular metastases. (Gut Liver 2016;10:283-287)

      • The Analysis of “Vocational Education 4.0” Form Based on “Industry 4.0”

        Wen-Ping ZHAO 한국직업자격학회 2017 한국직업자격학회 학술대회 Vol.2017 No.10

        “Industry 4.0” is a new form of social time which is based on the development of information technology. It brings great changes to people's production, life and work.And it also led to the new trend of the development of Vocational Education -- “vocational education 4.0”came into being.“Vocational education 4.0” form based on “industry 4.0”: The value orientation of vocational education,which is the service of personality, is a kind of service for the development of individualized career; The goal orientation of vocational education is to cultivate the technical talents with complex qualities; The content of the vocational education, which breaks the boundaries of discipline and specialty, forms the content of integration; to promote the optimization of vocational education mode of learning, namely in a variety of ways to promote effective learning.

      • KCI등재

        A Trial Study of Moxibustion with a Warming Needle on Edema

        Wen-Ping Zhang,Yuki Onose,Takahiko Fujikawa 사단법인약침학회 2017 Journal of Acupuncture & Meridian Studies Vol.10 No.1

        Edema is an accumulation of an excessive amount of watery fluid in cells or intercellular tissues. In order to examine the effects of acupuncture and moxibustion on edema, seven subjects were randomly divided into three groups, that was a Control group, an Acupuncture group (Acp), and an acupuncture and moxibustion group (Acp-Mox). After sitting for 60 minutes keeping their bodies still, the Acp and Acp-Mox subjects were administered acupuncture or acupuncture/moxibustion on the points of Zusanli (ST-36) and Sanyinjiao (SP-6), separately as against the Control group who only lied on the bed after modelization. After modelization at 60 minutes, the skin temperature and blood flow of all the groups were significantly lower in blood flow when compared with premodelization. But shortly after the procedure at 80 minutes, skin temperature in the Acp and Acp-Mox groups were significantly increased when compared with premodelization (vs. 60 minutes, p < 0.05). Moreover, the skin temperature and blood flow of the Acp-Mox group were significantly increased as compared to both the Control and the Acp group at the 80-minute time point. These results indicate that Acp and Mox-Acp could relieve edematous conditions significantly, especially the procedure of moxibustion with warming needle, was effective in improving edema which is often accompanied with cold intolerance and would be a recommended and superior therapy for edema.

      • KCI등재

        Design of Micro Biopsy Device for Wireless Autonomous Endoscope

        Wen-Wen Chen,Guo-Zheng Yan,Hua Liu,Ping-Ping Jiang,Zhi-Wu Wang 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.

        Well-established technology that provides assistance from outside the patient may soon give way to alternative approaches that bythe wireless robotic mechanisms inside the patient through natural orifices. For this study, two kinds of micro biopsy mechanisms weredeveloped for capsule endoscope which could traverse the gut environment automatically. This mobility allows the biopsy device tomove to the area of interest to sample specific tissues. Based on the medical and mechanism considerations, we concerned on designprecise biopsy jaw with sufficient cutting force, and the biopsy process should be safe, repeatable and visible. The lead-screw linkagesystem that actuated jaw of biopsy allowing for large force production. Using one micro-motor, the biopsy process was carried outquickly by three motions: stretching to sampling point; bite and cutting off; withdrawing into capsule body with the sample. With thecontrol and vision system, the biopsy process could compete automatically. The robot was capable of traversing in the gut environmentwirelessly and had been successfully used to biopsy gut tissue in vitro. In addition, experimental analysis of the biopsy mechanismshowed good results towards more elaborate tissue manipulation in the future.

      • Expression and Significance of Hypoxia Inducible Factor-1α and Lysyl Oxidase in Non-small Cell Lung Cancer

        Ping, Wei,Jiang, Wen-Yang,Chen, Wen-Shu,Sun, Wei,Fu, Xiang-Ning Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

        Object: To detect expression of hypoxia inducible factor-$1{\alpha}$ (HIF-$1{\alpha}$) and lysyl oxidase (LOX) in non-small cell lung cancer (NSCLC) and explore their roles in prognosis. Methods: The mRNA levels of HIF-$1{\alpha}$ and LOX were investigated by real-time reverse-transcriptase polymerase chain reaction in 40 cases of tumour and paired normal tissues. In addition, protein expression of HIF-$1{\alpha}$ and LOX was examined by immunohistochemistry in 82 cases of tumour and 45 paired normal tissues. The relationship between HIF-$1{\alpha}$ or LOX and clinicopathologic characteristics, as well as the correlation between HIF-$1{\alpha}$ and LOX, were also examined. Kaplan-Meier survival curves and the log-rank test were used to analyze progression-free survival. Results: HIF-$1{\alpha}$ or LOX mRNA levels in tumor tissues was significantly higher than those in paired normal tissues (p<0.01). Positive HIF-$1{\alpha}$ or LOX protein expression in tumor tissues was noted in 46/82 (56.1%) and 49/82 (59.8%) of the cases, respectively, being significantly higher than those in paired normal tissues (p<0.05). There was significant correlation between the expression of HIF-$1{\alpha}$ or LOX and tumor size, lymph node metastasis and pathological stage (p<0.05). The expression of HIF-$1{\alpha}$ and LOX had a significant inverse impact on survival of patients with NSCLC. Conclusion: HIF-$1{\alpha}$ and LOX may play a pivotal role in the development of NSCLC, and may act in synergy to promote the progression of NSCLC.

      • KCI등재

        Endovascular Treatment for Iliac Vein Compression Syndrome: a Comparison between the Presence and Absence of Secondary Thrombosis

        Wen-Sheng Lou,Jian-Ping Gu,Xu He,Liang Chen,Hao-Bo Su,Guo-Ping Chen,Jing-Hua Song,Tao Wang 대한영상의학회 2009 Korean Journal of Radiology Vol.10 No.2

        Objective: To evaluate the value of early identification and endovascular treatment of iliac vein compression syndrome (IVCS), with or without deep vein thrombosis (DVT). Materials and Methods: Three groups of patients, IVCS without DVT (group 1, n = 39), IVCS with fresh thrombosis (group 2, n = 52) and IVCS with non-fresh thrombosis (group 3, n = 34) were detected by Doppler ultrasonography, magnetic resonance venography, computed tomography or venography. The fresh venous thrombosis were treated by aspiration and thrombectomy, whereas the iliac vein compression per se were treated with a self-expandable stent. In cases with fresh thrombus, the inferior vena cava filter was inserted before the thrombosis suction, mechanical thrombus ablation, percutaneous transluminal angioplasty, stenting or transcatheter thrombolysis. Results: Stenting was performed in 111 patients (38 of 39 group 1 patients and 73 of 86 group 2 or 3 patients). The stenting was tried in one of group 1 and in three of group 2 or 3 patients only to fail. The initial patency rates were 95% (group 1), 89% (group 2) and 65% (group 3), respectively and were significantly different (p = 0.001). Further, the six month patency rates were 93% (group 1), 83% (group 2) and 50% (group 3), respectively, and were similarly significantly different (p = 0.001). Both the initial and six month patency rates in the IVCS patients (without thrombosis or with fresh thrombosis), were significantly greater than the patency rates of IVCS patients with non-fresh thrombosis. Conclusion: From the cases examined, the study suggests that endovascular treatment of IVCS, with or without thrombosis, is effective. Objective: To evaluate the value of early identification and endovascular treatment of iliac vein compression syndrome (IVCS), with or without deep vein thrombosis (DVT). Materials and Methods: Three groups of patients, IVCS without DVT (group 1, n = 39), IVCS with fresh thrombosis (group 2, n = 52) and IVCS with non-fresh thrombosis (group 3, n = 34) were detected by Doppler ultrasonography, magnetic resonance venography, computed tomography or venography. The fresh venous thrombosis were treated by aspiration and thrombectomy, whereas the iliac vein compression per se were treated with a self-expandable stent. In cases with fresh thrombus, the inferior vena cava filter was inserted before the thrombosis suction, mechanical thrombus ablation, percutaneous transluminal angioplasty, stenting or transcatheter thrombolysis. Results: Stenting was performed in 111 patients (38 of 39 group 1 patients and 73 of 86 group 2 or 3 patients). The stenting was tried in one of group 1 and in three of group 2 or 3 patients only to fail. The initial patency rates were 95% (group 1), 89% (group 2) and 65% (group 3), respectively and were significantly different (p = 0.001). Further, the six month patency rates were 93% (group 1), 83% (group 2) and 50% (group 3), respectively, and were similarly significantly different (p = 0.001). Both the initial and six month patency rates in the IVCS patients (without thrombosis or with fresh thrombosis), were significantly greater than the patency rates of IVCS patients with non-fresh thrombosis. Conclusion: From the cases examined, the study suggests that endovascular treatment of IVCS, with or without thrombosis, is effective.

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