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( Wan Seo ),( Hyoung Kyu Yoon ) 대한결핵 및 호흡기학회 2020 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.128 No.-
Background The neutrophil-to-lymphocyte ratio (NLR) in peripheral blood is an inexpensive and easily accessible biomarker for assessing the systemic inflammatory state of COPD patients. Previous studies showed relatively higher NLR levels in patients with COPD and its prognostic factor for future exacerbations. A plausible explanation for the underlying mechanism was the recruitment of neutrophils to the airways and subsequent increase of serum neutrophil count reflecting the acute and chronic inflammatory state of the lungs. In this study, we further looked for a possible role of the serum lymphocyte count in association with NLR. Methods A multicenter retrospective study was conducted by using the Korean COPD Subtype Study cohort (KOCOSS), which included 1043 COPD patients enrolled between July 2005 and July 2019. The patients were divided into four groups according to their NLR level (cut-off = 2.00) and serum lymphocyte count (cut-off = 2.0±0.5 103/μL): Group 1 (NLR ≥2, Lymphocyte <1.5 103/μL), Group 2 (NLR ≥2, Lymphocyte ≥1.5 103/μL), Group 3 (NLR <2, Lymphocyte ≥2.5 103/μL) and Group 4 (NLR <2, Lymphocyte <2.5 103/μL). Results The patients in Group 1 were significantly lower in weight and had lower serum hemoglobin, protein, albumin, and total cholesterol levels compared to the rest of the three groups. While there were no significant differences in the mMRC dyspnea scores, CAT scores, or SGRQ-C scores between the four groups, the FEV1 and the FVC were lower in Group 1 compared to those of Group 4 (1.72±0.68 liter vs. 1.92±0.66 liter, p=0.004; 3.27±0.87 liter vs. 3.47±0.79 liter, p=0.027). Univariate linear regression showed a significant association between Group 1 and FEV1 measured after a one-year follow-up (ß=-0.108, p=0.023). Conclusions When interpreting the NLR in COPD, patients with high NLR and lymphopenia should be given more clinical attention on the aspect of their body mass and nutritional status.
Long term management of people with posttuberculosis lung disease
Wan Seo,Hyung Woo Kim,Ju Sang Kim,Jinsoo Min 대한내과학회 2024 The Korean Journal of Internal Medicine Vol.39 No.1
Post-tuberculosis lung disease (PTLD) is emerging as a significant area of global interest. As the number of patients surviving tuberculosis (TB) increases, the subsequent long-term repercussions have drawn increased attention due to their profound clinical and socioeconomic impacts. A primary obstacle to its comprehensive study has been its marked heterogeneity. The disease presents a spectrum of clinical manifestations which encompass tracheobronchial stenosis, bronchiectasis, granulomas with fibrosis, cavitation with associated aspergillosis, chronic pleural diseases, and small airway diseases—all persistent consequences of PTLD. The spectrum of symptoms a patient may experience varies based on the severity of the initial infection and the efficacy of the treatment received. As a result, the long-term management of PTLD necessitates a detailed and specific approach, addressing each manifestation individually—a tailored strategy. In the immediate aftermath (0–12 months after anti-TB chemotherapy), there should be an emphasis on monitoring for relapse, tracheobronchial stenosis, and smoking cessation. Subsequent management should focus on addressing hemoptysis, managing infection including aspergillosis, and TB-associated chronic obstructive pulmonary disease or restrictive lung function. There remains a vast expanse of knowledge to be discovered in PTLD. This review emphasizes the pressing need for comprehensive, consolidated guidelines for management of patients with PTLD.
국내 판매중인 여성청결제의 사용실태 및 함유 보존제 분석
김완서(Wanseo Kim),윤영인(Youngin Youn),이고운(Gowoon Lee),박나연(Na-Youn Park),고영림(Younglim Kho),최경호(Kyungho Choi) 한국환경보건학회 2018 한국환경보건학회지 Vol.44 No.2
Objectives: Preservatives, suspected to be endocrine disrupting chemicals, are widely used in feminine hygiene products for the prevention of deterioration. Information regarding the usage patterns of feminine hygiene products and the concentrations of preservatives in these products is limited. The present study was conducted to investigate the use of feminine cleansers among Korean women and quantify the concentration of preservatives in feminine cleansers. Methods: Approximately 500 women were recruited from the city of Busan in August 2017 and a questionnaire survey was conducted on the use of feminine cleansers. Several major feminine hygiene products (n=69) were identified and selected for analysis of 22 preservatives. Following appropriate preparation, the products were analyzed by HPLC/DAD. Results: Over 70% of the participating women used at least one feminine cleanser. Marital status and parity were associated with the frequency of use. Liquid was most frequently used form of feminine cleanser (66.6%). The greatest proportion of subjects answered that they use it ‘one to two times per week’ (36.5%). Among the 69 feminine cleansers, benzoic acid, sorbic acid, phenoxyethanol, and methyl paraben were detected at 144-4,428 μg/g, 195-1,470 μg/g, 269-4,237 μg/g, and 625-4,901 μg/g, respectively. BA was the most frequently detected (46.4%). Conclusions: In the present study, the characteristics of feminine cleanser use among Korean women were investigated. Based on an analysis of preservatives in the feminine hygiene products, one product was determined to exceed the maximum authorized concentration of MeP (0.4%). Our results will help refine exposure and risk assessment for toxic chemicals in feminine cleansers.
≪조선말대사전(1992)≫ 동식물 풀이의 제3 메타언어 출현 양상과 의미 특성
김완서 ( Kim Wanseo ) 전북대학교 인문학연구소 2020 건지인문학 Vol.0 No.27
This study is aimed at classifying animal and plant secondary meta language features by type in the Joseonmal dictionary and looking at the meaning characteristics of each type. The second meta language was divided into four sections by type and 14 classes. Classes account for 76.9 percent of 'harm, drugs, meoggo/ meog-eumyeo/ meogneunda and medicine.' The sections were listed in the order of 'drugs', 'harmfulness', 'eating' and 'taste'. In the case of "meogneund," what can be eaten is limited to "little stems, young leaves," etc. The words used for 'taste' are 'meat' and 'flesh' and the expression also varies depending on the word. Meat is used as 'taste'. Flesh is used as 'fleshy and delicious'. "Drugs" become medicine in their own right, but "medcines" mean the ingredients used to make a drug. It is talking about a sea business that is "doing harm." The term "harming" specifically explains which part of crops and trees are harmed. The meaning of "meoggidohanda" mainly means that one part of a plant can be eaten as a medicine or as a food. In the case of "meog-eul su issda", one part may be used as both "eat" and "drug" or it may distinguish between food and drug usage by part.
디아스포라 미술의 어제와 오늘 : 서도호와 소그드인(Sogdian)
정완서(Jeong, Wanseo) 한국예술종합학교 미술원 조형연구소 2012 Visual Vol.9 No.-
얼마 전 리움Leeum 미술관에서 개인전을 마친 서도호는 한국에서 태어났지만, 미국을 기반으로 활동하는 작가이다. 그의 작업은 정체성, 디아스포라, 노마디즘 등 몇 개의 주제어로 설명할 수 있는데, 이러한 논의들은 정교한 포스트식민주의 이론을 기반으로 하고 있으며, 현대 다른 작가들에게서도 어렵지 않게 찾아 볼 수 있는 경향들이다. 흥미로운 사실은 1500여 년 전 중국에서도 자신의 정체성 이슈를 시각미술로 남긴 이들이 있었으니 그들은 바로 상업적, 정치적 이유로 중앙아시아에서 중국으로 이주해온 소그드인Sogdian들이다. 본 글에서는 거대 정주 국가인 중국과 전혀 상반된 역사, 전통, 문화를 가지고 있었던 소수 유목민족이 문화의 혼성과 통합 속에서 어떻게 정체성을 표현하고자 했는지, 현대 디아스포라 미술의 측면에서 살펴보기로 한다. Do Ho Suh who recently had a solo exhibition in Leeum was born in Korea but has worked mainly in the United States. His work could be epitomized by several keywords such as identity issue, diaspora, and nomadism. The discussions surrounding those topics are based on the elaborate postcolonialism theories. The trend is found in art discourses surrounding many other contemporary artists. Interestingly, as early as more than 1,500 years ago in China, there were people who created visual artworks talking about their identity problems; the Sogdians. They emigrated from Central Asia to China for commercial and political reasons. In this essay, I try to examine from an angle of rather contemporary diaspora art discourse how the ethnic minority who had totally different cultural and historical background from the Chinese tried to speak for their national identity in the midst of the cultural integration or hybridization.