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      • KCI등재

        Use of Parathyroid Hormone and Rehabilitation Reduces Subsequent Vertebral Body Fractures after Balloon Kyphoplasty

        Ueno Masaki,Toriumi Emi,Yoshii Aki,Tabata Yuki,Furudate Takeshi,Tajima Yusuke 대한척추외과학회 2022 Asian Spine Journal Vol.16 No.3

        Study Design: Retrospective cohort study.Purpose: To evaluate the efficacy of our current prophylactic strategy by investigating the incidence of subsequent vertebral body fractures (SVBFs) following balloon kyphoplasty (BKP).Overview of Literature: Although extensive studies have investigated the risk factors for SVBFs after BKP, few have reported on postoperative therapies to prevent SVBFs and have evaluated their effectiveness.Methods: This study enrolled 273 patients who underwent an initial BKP. To treat osteoporosis, parathyroid hormone (PTH) administration was started 1–2 weeks before BKP and continued for at least 6 months postoperatively. Corsets were applied for 3 months after the procedure. Rehabilitative interventions, including hip range-of-motion training, muscle strengthening exercises, and motion/posture instruction, were started from the preoperative assessment time point and resumed 3 hours postoperatively. Corsets were used in all patients. Therefore, no grouping based on corset use was performed. PTH was used in 180 patients, and they were divided into the following two groups: PTH user group and PTH nonuser group. Rehabilitative interventions were provided to all patients for a median duration of 17 days. Patients who underwent rehabilitative intervention for <17 and ≥17 days were included in the short-term and long-term intervention groups, respectively. The incidences of SVBFs for these four groups were compared.Results: SVBF occurred in 29 patients (10.6%). The SVBF incidence among patients who were prescribed all three prophylactic measures was 6.2%. The PTH user group had a significantly lower incidence of distant vertebral body fractures as compared to the PTH nonuser group. The long-term rehabilitation group had a significantly lower incidence of SVBFs and adjacent vertebral body fractures within 50 postoperative days than the short-term group.Conclusions: A 17-day or longer rehabilitative intervention may lower the risk of early adjacent vertebral body fractures, and the use of PTH may reduce the risk of distant vertebral body fractures.

      • Thermal and Chemical Recycling of Waste Plastics Using Solid Acids and Bases Design of Recyclable Polystyrene Films for Better Environments

        Ueno, Akifumi 전남대학교 촉매연구소 1996 촉매학술발표회 Vol.- No.13

        Catalysts employed were various solid acids and bases, as given in Table 1, where the amount of distillates yielded and their compositions are also noted. It was found that solid bases were more effective for the recovery of styrene containing both monomer and dimer than solid acids, which were commercially employed for the production of fuel oils from waste polyolefins such as polyethylene and polypropylene. The styrene monomer and dimer obtained could be used for the production of polystyrene again. One of the features of distillates obtained by solid acids is the coexistence of benzene and indan, which was never observed in the distillates obtained by solid bases. This comes from the difference in the degradation mechanisms over solid acids and bases. Since it was found that more than 85% of polystyrene was converted into styrene monomer and dimer at 623 K over BaO powder, finely divided BaO was dispersed into polystyrene pellet when molded into polystyrene films by means of a heating twin-roller made of stainless steel. The amounts of BaO powder dispersed into films were varied from 1 to 10 wt% of polystyrene pellet used. The films thus prepared were crushed into tiny pieces and were success fully degraded into styrene monomer and dimer at 623 K without addition of other catalytic materials. Styrofoams were prepared from the polystyrene films dispersing a small amount of BaO powder using nitrogen as a foaming gas. Thus, the styrofoams dispersing catalyst were developed as a model of environment friendly plastics, since the styrofoams were easily converted into styrene simply by heating at 623 K when wasted.

      • Anionic Effects on Solvate Ionic Liquid Electrolytes in Rechargeable Lithium–Sulfur Batteries

        Ueno, Kazuhide,Park, Jun-Woo,Yamazaki, Azusa,Mandai, Toshihiko,Tachikawa, Naoki,Dokko, Kaoru,Watanabe, Masayoshi American Chemical Society 2013 JOURNAL OF PHYSICAL CHEMISTRY C - Vol.117 No.40

        <P>A series of equimolar mixtures of Li salts (LiX) and glymes (triglyme (G3) and tetraglyme (G4)), [Li(glyme)]X with different anions (X: [N(SO<SUB>2</SUB>C<SUB>2</SUB>F<SUB>5</SUB>)<SUB>2</SUB>] = [BETI]; [N(SO<SUB>2</SUB>CF<SUB>3</SUB>)<SUB>2</SUB>] = [TFSA]; [CF<SUB>3</SUB>SO<SUB>3</SUB>] = [OTf]; BF<SUB>4</SUB>; NO<SUB>3</SUB>), were used as electrolytes to study the anionic effects of [Li(glyme)]X on the performance of lithium–sulfur (Li–S) batteries. The dissolution of lithium polysulfides (Li<SUB>2</SUB>S<SUB><I>m</I></SUB>), which are discharge products of elemental sulfur, was significantly suppressed in the solvate ionic liquid (IL) electrolytes, as seen in [Li(G4)][BETI] and [Li(glyme)][TFSA], wherein all of the glymes participated in the formation of the complex cation [Li(glyme)]<SUP>+</SUP>. It was found that NO<SUB>3</SUB> anions were irreversibly reduced at the composite cathode during discharge and BF<SUB>4</SUB> anions formed unexpected byproducts through a chemical reaction with the polysulfide anions. Successful charge/discharge of Li–S cell could not be performed in [Li(glyme)]X in the presence of these anions because of the undesired side reactions. The solvate IL [Li(G4)][BETI] was found to be electrochemically stable in the Li–S cell and allowed a stable operation with a capacity of 600–700 mAh·g<SUP>–1</SUP> and a Coulombic efficiency of 98.5% over 100 cycles, similar to that achieved by [Li(glyme)][TFSA]. In contrast, the Li–S cell with a concentrated electrolyte solution, [Li(G3)][OTf], showed a much lower capacity and Coulombic efficiency.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jpccck/2013/jpccck.2013.117.issue-40/jp407158y/production/images/medium/jp-2013-07158y_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/jp407158y'>ACS Electronic Supporting Info</A></P>

      • SCOPUSKCI등재

        TRICHOTHECENES AS ENVIRONMENTAL TOXICANTS

        Ueno, Yoshio The Korean Society of Toxicology Korea Environment 1985 Toxicological Research Vol.1 No.1

        The trichothecenes are a chemically related sesquiterpenoid fungal metabolites of Fusarium, Trichoderma, Stachybotrys and others, and at moment more than 70 kinds of derivatives are identified. Historically, they are identified as antifungal and phytotoxic compounds, but after the finding of T-2 toxin from Fusarium tricinctum, several trichothecenes are now considered to be natural toxicants in foodstuffs and feeds.

      • Suppressive Effect of Pioglitazone, a PPAR Gamma Ligand, on Azoxymethane-induced Colon Aberrant Crypt Foci in KK-A<sup>у</sup> Mice

        Ueno, Toshiya,Teraoka, Naoya,Takasu, Shinji,Nakano, Katsuya,Takahashi, Mami,Yamamoto, Masafumi,Fujii, Gen,Komiya, Masami,Yanaka, Akinori,Wakabayashi, Keiji,Mutoh, Michihiro Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

        Obesity is an established risk factor for colorectal cancer. Pioglitazone is a peroxisome proliferator activated receptor$receptor{\gamma}$ ($PPAR{\gamma}$) agonist that induces differentiation in adipocytes and induces growth arrest and/or apoptosis in vitro in several cancer cell lines. In the present study, we investigated the effect of pioglitazone on the development of azoxymethane-induced colon aberrant crypt foci (ACF) in KK-$A^{\mathcal{Y}}$ obesity and diabetes model mice, and tried to clarify mechanisms by which the $PPAR{\gamma}$ ligand inhibits ACF development. Administration of 800 ppm pioglitazone reduced the number of colon ACF/mouse to 30% of those in untreated mice and improved hypertrophic changes of adipocytes in KK-$A^{\mathcal{Y}}$ mice with significant reduction of serum triglyceride and insulin levels. Moreover, mRNA levels of adipocytokines, such as leptin, monocyte chemoattractant protein-1 and plasminogen activator inhibitor-1, in the visceral fat were decreased. PCNA immunohistochemistry revealed that pioglitazone treatment suppressed cell proliferation in the colorectal epithelium with elevation of p27 and p53 gene expression. These results suggest that pioglitazone prevented obesity-associated colon carcinogenesis through improvement of dysregulated adipocytokine levels and high serum levels of triglyceride and insulin, and increase of p27 and p53 mRNA levels in the colorectal mucosa. These data indicate that pioglitazone warrants attention as a potential chemopreventive agent against obesity-associated colorectal cancer.

      • KCI등재

        Insect natural enemies as bioindicators in rice paddies

        Ueno, Takatoshi Institute of Agricultural Science 2012 Korean Journal of Agricultural Science Vol.39 No.4

        In Asia, including Japan and Korea, rice paddies occupy the largest cultivated area in agricultural land. Rice paddies provide the habitats for many organisms including endemic species, sustaining high biodiversity. Insect natural enemies inhabiting rice paddies have an important function for rice production as agents of 'ecosystem services' because they play a major role in suppressing rice pests. The diversity and abundance of natural enemies can be a good index reflecting the 'healthiness' of agro-ecosystem services in rice paddies. The present study investigates whether insect natural enemies could be good biological indicators for general arthropod biodiversity and agricultural practice. First, the concept of ideal bio-indicators was summarized. The strategy to explore and select such bio-indicators was then proposed. Lastly, field survey was made to evaluate the abundance and biodiversity of natural enemies in Japanese rice paddies where chemical inputs, i.e., insecticide use, were different. The results showed that reduction of chemical inputs led to an increase in species richness or diversity of natural enemies including parasitoids and predators. Then, the data were analyzed to examine suitable indicator species to assess environmental soundness of agricultural practice and biodiversity in rice paddies. The density of several species of natural enemies did respond both to pesticide use and to general arthropod biodiversity. The analyses thus have indicated that natural enemies can be suitable as bio-indicators. Usefulness of indicator species in rice paddies is discussed in the context of ecologically sound agriculture.

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