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      • KCI등재

        Effect of Laser Treatment on Pigment Printing on Denim Fabric -A Study of Colour Properties

        Shun-ting Tse,Chi-wai Kan 한국섬유공학회 2022 Fibers and polymers Vol.23 No.3

        In this study, denim fabric samples were pigment printed with and without laser treatment, the two commonly usedmethods in textile and fashion industry for adding colour effect to denim fabric. Various pigment printing and laser treatmentparameters were used and their relationships with final colour properties of the denim fabric samples were investigated. Afterthe treatments, colour properties of denim fabric samples were evaluated by CIE L*, CIE a*, CIE b* and CIE ΔE values. Experimental results revealed that lightness (CIE L* value) of denim fabric samples was affected by the mesh count, laserintensity and the sequence of applying pigment printing and laser treatment. It was found that a redder (evaluated by CIE a*value) and yellower (evaluated by CIE b* value) denim fabric samples were produced by applying laser before pigmentprinting.

      • KCI등재

        Community-based Informed Agents Selection for Flocking with a Virtual Leader

        Nuwan Ganganath,Chi-Tsun Cheng,Xiaofan Wang,Chi K. Tse 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.1

        It has been studied that a few informed individuals in a group of interacting dynamic agents can influencethe majority to follow the position and velocity of a virtual leader. Previously it has been shown that a cluster-basedselection of informed agents can drive more agents to follow the virtual leader compared to a random selection. However, a practical question is: How many informed agents to select? In order to address this, here we proposea novel method for selecting informed agents based on community structures in the initial spatial distribution ofagents. The number of informed agents are decided based on the strongest community structure. We test andanalyze the performance of the proposed method against random and cluster-based selections of informed agentsusing extensive computer simulations. Results of our study show that community-based selection can be usefulin deciding an optimum number of informed agents such that a majority of the group can achieve their commonobjective.

      • KCI등재

        Quantitative Anatomy of C7 Vertebra in Southern Chinese for Insertion of Lateral Mass Screws and Pedicle Screws

        Michael Siu Hei Tse,Chi Hin Chan,Kam Kwong Wong,Wing Cheung Wong 대한척추외과학회 2016 Asian Spine Journal Vol.10 No.4

        Study Design: Retrospective study. Purpose: To analyze the quantitative anatomy of C7 vertebra for insertion of lateral mass screws and pedicle screws in Southern Chinese patients. Overview of Literature: C7 lateral mass is smaller when compared to other subaxial cervical levels, which limits the length of lateral mass screws that can be used. Some studies have suggested pedicle screws for better fixation. But, this option is limited by the narrow pedicle width. Methods: We have obtained computed tomography (CT) cervical spine data in 0.625 mm slices from our radiology department. The patients were adults. CTs were from May to August, 2015. The lateral mass screw length was measured using Margerl’s technique and pedicle width and pedicle screw trajectory were determined in three-dimensional reformated images. Results: CT scans of cervical spines of 94 patients were obtained and 188 lateral masses and pedicles of C7 vertebrae were measured. The mean lateral mass screw length was 13.2 mm (standard deviation [SD] 1.6 mm), mean outer pedicle width was 5.9 mm (SD 1.0 mm) and mean pedicle screw trajectory was 29.4 degrees (SD 3.6 degrees). Most (91.0%) of the pedicles had an outer diameter ≥4.5 mm. Conclusions: The mean lateral mass screw length was longer when compared with other similar studies, while the mean outer pedicle width was narrower. Nearly 10% of the pedicles were unable to accommodate 3.5 mm screws. These findings favor the use of lateral mass screws to provide a safe and stable fixation for C7 vertebrae in Southern Chinese patients, while the final choice of fixation method should only be confirmed after careful preoperative planning with CT scan.

      • Clinical Relevance and Functional Role of Nuclear Met in Hepatocellular Carcinoma

        ( Sze Keong Tey ),( Edith Yuk Ting Tse ),( Frankie Chi Fat Ko ),( Xiao Wen Mao ) 대한간학회 2016 춘·추계 학술대회 (KASL) Vol.2016 No.1

        Aims: Met is a receptor tyrosine kinase which triggers a wide range of normal physiological signaling cascades. However, a perturbation of the Met pathway is commonly found in human cancers. Emerging evidence has shown the presence of nuclear Met in some cancerous tissues and cell lines, suggesting that nuclear Met could have unexplored functions in the nucleus. The present study aimed to assess the expression and functions of nuclear Met in hepatocellular carcinoma (HCC). Methods: Nuclear Met expression of 103 clinicopathologically characterized HCC paired samples was examined by immunohistochemistry using an antibody against the carboxyl terminus of Met. Statistical analyses were applied to evaluate the association of nMet with different clinical parameters. Nuclear localization of Met was determined by western blot analysis and immunofluorescence microscopy. Met cytoplasmic fragments were characterized by in vitro functional assay such as migration, invasion and proliferation in HCC cells. Nude mice model was employed to investigate the in vivo functional impact of nuclear Met. Results: Nuclear Met is overexpressed in nearly 90% of HCC paired samples and its expression is progressively increased along HCC development from non-tumorous liver tissue to advanced HCC. Nonetheless, nuclear Met overexpression is significantly associated with venous invasion and poorer overall survival. We found that nuclear Met, which has a lower molecular weight than Met, could only be detected using an antibody against the carboxyl terminus of Met (C28) in tumorous tissues. This finding strongly suggests that nuclear Met only comprises of the carboxyl cytoplasmic region of full length Met. Moreover, both western blot analysis of nuclear fraction of HCC cells and immunofluorescence confirmed the nuclear localization of Met. We designed construct J1, J3 and T2 that encode Met fragment truncated after tyrosine residues D972 and P1027 in the juxtamembrane region and after tyrosine kinase domain beginning at L1157, respectively. Immunofluorescence microscopy showed both J1 and J3 constructs are dominantly expressed in the nucleus whereas T2 construct is expressed in the cytoplasm. These observations indicated the region in between J1 and T2 as the important region that facilitates the nuclear localization of Met. In vitro functional assay showed that nMet significantly promoted HCC cell proliferation and anchorage independent growth. It also significantly augmented HCC cell migration and invasiveness. Besides that, nMet also enhanced HCC tumor formation in animal model. Furthermore, we showed that nMet promoted tumor invasiveness and aggressiveness through NF-κ B/MMP2 pathway. Conclusions: Nuclear Met is overexpressed and associated with venous invasion and poorer overall survival in HCC. We found that nuclear Met is actually the carboxyl terminal fragment of Met and translocates into nucleus to promote invasiveness in HCC cells.

      • KCI등재

        Enhancement of Elemental Sulfur Recovery from Wastewater Biogas Using Nickel (II)-(5,10,15,20)-tetrakis-phenylcarboxylporphyrin

        Chun-Yin Lau,Jianyu Guan,Ho-Yin TSE,Chi Shun Yeung,Chiu Wing Shum,Shao-Yuan Leu 대한토목학회 2020 KSCE Journal of Civil Engineering Vol.24 No.5

        Sulfide control is a vital issue affecting the regional air quality and operational safety in sewage treatment processes. The conventional sulfide removal techniques are sophisticated industrial processes which require large operational footprint or are related to hazardous chemicals. In this study, the performance of elemental sulfur recovery from a simple micro-aeration process with metal-TCPP ((5,10,15,20)-tetrakis-p-carboxyphenylporphyrin) was investigated through laboratory experiments. A minimum of fourfold enhancement of elemental sulfur recovery was achieved from sulfide dissolved wastewater with the addition of nickel (II) TCPP, which demonstrated the highest among seven various types of transition metal-porphyrin complexes in the 3d block elements. The optimized reaction conditions resulted in 72.53% sulfur recovery with the addition of only 4.5 ppm nickel into the solution. The catalyst significantly improves the recyclability and life-cycle of the water-based absorbent and provides benefits to odor control and resource recovery.

      • A Low-Cost Method for Minimizing the Chromaticity Shift of DC-Driven Phosphor-Converted White LEDs by Thermal Design

        K. H. Loo,Y. M. Lai,Chi K. Tse 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5

        Most commercial white LEDs are made from blue LEDs coated with YAG phosphor. They generally produce emission spectra that shift in opposite directions under the influences of current amplitude and junction temperature changes. By using a commercial white LED sample, LUXEON K2, the effects of current amplitude and junction temperature on the chromaticity shift of white LEDs over dimming, during which both parameters are known to assert their influences simultaneously, are studied experimentally. The impact of driving/dimming by dc current is discussed through a graphical analysis and verified by experimental measurement. Due to the counteracting influences of current amplitude and junction temperature changes, driving/dimming white LEDs by dc current offers a more superior chromaticity stability compared to PWM. By means of selection of a heat sink’s thermal resistance estimated from an analytical equation derived in this paper, it is found that the overall chromaticity shift of white LEDs over dimming can be minimized at low cost.

      • Clinical Significance of Smudge Cells in Peripheral Blood Smears in Hematological Malignancies and Other Diseases

        Chang, Chih-Chun,Sun, Jen-Tang,Liou, Tse-Hsuan,Kuo, Chin-Fu,Bei, Chia-Hao,Lin, Sheng-Jun,Tsai, Wei-Ting,Tan, N-Chi,Liou, Ching-Biau,Su, Ming-Jang,Yen, Tzung-Hai,Chu, Fang-Yeh Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4

        Background: It is reported that the percentage of smudge cells in the blood smear could be a prognostic indicator in chronic lymphocytic leukemia. However, the clinical significance of smudge cells in other hematological malignancies, solid tumors or non-malignant diseases is less clear. Hence, this study was conducted to survey the clinical significance of smudge cells in hematological cancers and other disorders. Materials and Methods: From January to November, 2015, the clinical data of patients who received blood examination with differential counts for clinical purpose and were found to have smudge cells in the peripheral blood film in Far Eastern Memorial Hospital were selected. The percentage of smudge cells and patient outcomes were evaluated for further univariate and survival analyses. Results: A total of 102 patients with smudge cells in their blood smears were included. Smudge cells were frequently presented in out-of-hospital cardiac arrest (OHCA; n=30), infections (n=23), hematological cancers (n=23) and solid cancers (n=10). There was no relationship between the percentage of smudge cells and the patient mortality in all diseases (OR: 1.08, 95% CI: 0.47-2.48, P=1.000) as well as the OHCA group (OR: 1.91, 95% CI: 0.38-9.60, P=0.694). It was observed that in patients with all cancers with the percentage of smudge cells less than 50% had a lower mortality rate in comparison with those who had the percentage of smudge cells of 50% or more (OR: 22.29, 95% CI: 2.38-208.80, P<0.001). Additionally, it was seemingly that patients with smudge cells of 50% or more had a lower survival rate than those with smudge cells less than 50% in all cancers with follow-up at 2-month intervals, but without statistical significance (P=0.064). Conclusions: Our survey indicated that in all cancers, those who had higher percentage of smudge cells were prone to have poor outcomes when compared with the subjects with lower percentage of smudge cells. This finding was quite different from the results of previous studies in which the race-ethnicity of most study populations was non-Asian; hence, further investigations are required. Besides, there was no apparent association of the percentage of smudge cells with patient outcomes in all diseases, including OHCA.

      • Prognostic Factors in Adult Patients with Solid Cancers and Bone Marrow Metastases

        Hung, Yu-Shin,Chou, Wen-Chi,Chen, Tai-Di,Chen, Tse-Ching,Wang, Po-Nan,Chang, Hung,Hsu, Hung-Chih,Shen, Wen-Chi,Cheng, Wei-Hong,Chen, Jen-Shi Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1

        Background: Solid cancers with bone marrow metastases are rare but lethal. This study aimed to identify clinical factors predictive of survival in adult patients with solid cancers and bone marrow metastases. Methods: A total of 83 patients were enrolled consecutively between January 1, 2000 and December 31, 2012. Bone marrow metastases were confirmed by biopsies. Patient clinical features and laboratory data were analyzed for associations. Results: The median age of the patients was 54 years (range, 23-88 years), and 58% were male. The 3 most common primary tumor locations were the stomach (32 patients, 39%), prostate (16 patients, 19%), and lungs (12 patients, 15%). The median overall survival was 49 days (range, 3-1423 days). Patients with Eastern Cooperative Oncology Group performance status 1, cancers of prostate origin, platelet counts over 50,000/ml, and undergoing antitumor therapies had a significantly better prognosis in the multivariate analysis. The median survival times were 173 and 33 days for patients with 2-3 more favorable parameters (n=24) and those with 0-1 (n=69), respectively (hazard ratio 0.30; 95% CI 0.17-0.52, p<0.001). Conclusions: Solid cancers with bone marrow metastases are dismal and incurable diseases. Understanding prognostic factors to these diseases helps medical personnel to provide appropriate treatments and better inform patients about outcomes. Antitumor therapies may improve outcomes in selected patient cohorts.

      • KCI등재

        Management of Malignancies Developing in AYA

        Alex WK. Leung,Herbert HF. Loong,Teresa Tse,Chi-kong Li 대한소아혈액종양학회 2021 Clinical Pediatric Hematology-Oncology Vol.28 No.1

        Adolescent and young adult (AYA) with cancers have distinct spectrum of cancers as compared to younger and older age groups. The definition of age limits of AYA varies among countries, from 15-25 years to 12-39 years. The differences in age definition lead to variation in report of incidence, types of cancers and survival. In younger AYA patients, hematological malignancies are leading cause of cancers. In older AYA patients, testicular cancers are common in males while breast cancers and cervical cancers are predominant types in females. There is increasing incidence of AYA cancers worldwide in the past two decades. Overall survival and treatment outcome of AYA cancer has been improving in the last few decades. Specialized centers for AYA with cancers provide more comprehensive care and have been reported to have superior outcome. About 80% of AYA with cancers survive at 5 years after diagnosis but they are higher risk of developing second malignancies. Barriers to AYA cancer treatment included social economic status, insurance system and accessibility to clinical trials. Survivors of AYA cancers are also at higher risk dying from cardiovascular diseases and respiratory diseases. Survivorship program should be in place to enhance education and surveillance.

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