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Suzuki, Nobutaka,Takimoto, Yuko,Suzuki, Riho,Arai, Takanari,Uebaba, Kazuo,Nakai, Masuo,Strong, Jeffry Michael,Tokuda, Harukuni Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6
Extract of Lentinula edodes mycelia (LEM) is currently utilized as an oral biological response modifier (BRM) medicine for cancer patients. However, its effectiveness for breast cancer patients with postoperative adjuvant hormone therapy has not yet been scientifically verified. In this study, we investigated the influence of LEM on the quality of life (QOL) and immune response in breast cancer patients undergoing postoperative adjuvant hormone therapy. Twenty patients were studied in total. They received only hormone therapy in the first 4 weeks followed by hormone therapy and LEM during the next 8 weeks. Laboratory tests, QOL score and peripheral blood cytokine production levels were evaluated during the study period. No changes in QOL or cytokines were noted after the first 4 weeks. In contrast, during the following combined therapy period, improvements were noted in QOL and cytokine levels. Although a future large-scale investigation is necessary to confirm these results, these data suggest that the concomitant use of LEM with postoperative adjuvant hormone therapy improves the QOL and immune function of patients.
VTOL mode controller for a mini-UAV having a side-force fin
Shinichi Hashimoto,Nobuhiro Yokoyama,Yoshimasa Ochi,Hideo Adachi,Natsuki Kondo,Toshiaki Yamashita,Takanari Arai 한국항공우주학회 2008 한국항공우주학회 학술발표회 논문집 Vol.- No.-
A UAV (Unmanned Aerial Vehicle) currently developed by the authors is a kind of flying wing. One of features of the UAV is its capability of vertical takeoff and landing as a tail-sitter. Thus, it is possible to operate it flexibly by reducing the space restrictions on the takeoff and landing. In this work, we designed a gain-scheduled controller for the vertical takeoff and landing, which can vary the control gain in accordance with the varying state of the vehicle. We applied a method that solves Lyapunov stability conditions on all the design points simultaneously by using linear matrix inequalities (LMI). The effectiveness of the controller is demonstrated through the numerical simulations.
Kim, Ick Soo,Sung, Jang Hyun,Kang, Chang Yong,Okuda, Takanari,Maziasz, Philip J .,Klueh, Ronald L .,Miyahara, Kazuya 대한금속재료학회(대한금속학회) 2000 METALS AND MATERIALS International Vol.6 No.6
The effects of several oxide species, such as Y₂O₃, ZrO₂ and MgO, and the thermomechanical treatment (TMT) after the mechanical alloying (MA) process on the strength properties of Fe-17%Cr ferritic ODS (oxide dispersion strengthening) MA materials were investigated. Y₂O₃ showed the most uniform dispersion of the finest particles among the above oxides, but the microstructural evolution during the TMT had a larger effect on the strengthening of the alloys than the fine and uniform dispersion of the Y₂O₃ particles had.
Design of a PID Flight Control System for an MAV having a Side-force Fin
Yoshimasa Ochi,Hiroyuki Kondo,Nobuhiro Yokoyama,Hideo Adachi,Natsuki Kondo,Toshiaki Yamashita,Takanari Arai 한국항공우주학회 2008 한국항공우주학회 학술발표회 논문집 Vol.- No.-
This paper describes dynamic properties and a night control system of an MAY (mini aerial vehicle) hal ing a side-force fin. We are developing a nonlinear model of the MAY through flight/wind tunnel experiments and CFD anal) sis. A linear model is obtained from the current nonlinear model. Using the linear model, we have designed a !light control system (FCS) that controls the altitude, forward speed, roll angle. and heading angle with thrust. elevator. aileron. and the sideforce fin. respectively. The side-force fin produces direct side-force that achieves skid-to-turn without bank in cooperation with the aileron. The FCS is designed as a PID control system, whose gains are determined based on the integral-type optimal servo, Although the design method has theoretically not been established, it provides PID gains via a simple design procedure and its usefulness and effectiveness have been proved through various design examples, Also in this study, computer simulation and analysis demonstrate how the FCS works.
Endoscopic features of gastrointestinal stromal tumor in the small intestine
Yutaro Ihara,Takehiro Torisu,Tomohiko Moriyama,Junji Umeno,Atsushi Hirano,Yasuharu Okamoto,Yoshifumi Hori,Hidetaka Yamamoto,Takanari Kitazono,Motohiro Esaki 대한장연구학회 2019 Intestinal Research Vol.17 No.3
Background/Aims: Gastrointestinal stromal tumor (GIST) is one of the most common types of submucosal tumors (SMTs). Because of GIST’s malignant potential, it is crucial to differentiate it from other SMTs. The present study aimed to identify characteristic endoscopic findings of GISTs in the small intestine. Methods: We reviewed the clinicopathological and endoscopic findings of 38 patients with endoscopically or surgically resected SMTs in the small intestine. SMTs were classified into GIST and non-GIST groups, and clinicopathological and endoscopic findings were compared between the 2 groups. Results: Fifteen patients had GIST and 23 patients had other types of SMTs in the small intestine. Comparison of the endoscopic findings between the 2 groups revealed that dilated vessels in the surrounding mucosa were significantly more in number in the GIST group than in the non-GIST group (P<0.05). However, there were no other differences in endoscopic findings between the 2 groups. Among patients with GISTs, the presence of dilated vessels in the surrounding mucosa was not associated with bleeding risk, tumor size, or metastasis rate at diagnosis. Conclusions: Dilated vessels in the surrounding mucosa, identified during balloon-assisted endoscopy, may be a diagnostic indicator for GIST in the small intestine. However, its clinical significance should be further analyzed.