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朴錫潤 충남대학교 자연과학연구소 1980 學術硏究誌 Vol.7 No.2
The possibility of serial correlation of disturbances presents a serious problem in time series regression analysis. In this paper the basic theory upon which several tests of the independence of least squares regression disturbance are based is reviewed.
과시적 분권과 기술적 집권 : 90년대의 지방분권화 Korea's Decentralization Policy in the 1990s
김석태 서울대학교 행정대학원 2000 行政論叢 Vol.38 No.1
우리나라는 1980년대 후반부터 지방분권을 국가의 주요 정책으로 표방하였다. 지방의회의 부활과 지방자치단체장의 민선 그리고 주민 참정권을 확대하는 일련의 개혁은 그 결실이라 할 수 있다. 하지만 이런 분권적 개혁에 못지 않게 지방의회의 입법권을 제약하고, 단체장의 권한을 약화시키는 집권적인 제도도 도입되었다. 이 논문은 90년대의 분권·집권적인 제도 변화를 적시하는 20여 가지 사례들을 정리하고, 이런 변화의 특징을 과시적 분권, 기술적 집권 그리고 지방자치단체장의 권한 약화로 규정한다. 그 다음 이런 변화를 긍정적으로 이해하려는 가부장주의적 입장과 이를 부정적 시각으로 보는 공공선택론적 입장으로 나누어 설명한다.
Aspergillus candidus F1484 균주가 생산하는 항진균 화합물의 분리 및 특성
김성옥,이소영,김성규,손광희,김영국,문석식,복성해 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.5
Candida albicans의 효모형태에 대해 활성을 나타내는 항진균 물질의 탐색 중에 Aspergillus candidus F1484 균주의 발효액으로부터 항진균 화합물 F1484를 단리하고 ethyl acetate 추출, silica gel column chromatography, ODS column chromatography 및 preparative HPLC를 행하여 분리정제하였다. F1484 화합물은 EI-MS, ^13C-, ^1H-NMR, DEPT, HMQC 및 HMBC에 의한 구조분석을 행한 결과 이 화합물은 항진균 물질인 chloroflavonin과 동일한 구조를 나타내었으며 효모형태의 Candida albicans에 대한 항진균 활성뿐만 아니라 여러 종류의 인체 종양 세포주에 대해서도 세포독성을 나타내었다. In the course of screening for the antifungal compounds against Candida albicans, an antifungal compound (F1480) was isolated from the culture broth of Aspergillus candidus F1484. Isolation and purification of compound F1484 were performed using ethyl acetate extraction, silica gel column chromatography, ODS column chromatography, and preparative HPLC. The structure of compound F1484 was determined by the spectroscopic analyses of EI-MS, ^13C-, ^1H-NMR, DEPT, HMQC, and HMBC. This compound appeared to have a structure of antifungal agent, chloroflavonin. In addition to antifungal activities against the yeast phase of Candida species, compound F1484 showed cytotoxic effect against various human tumor cell lines.
Tsaokoarylone, a Cytotoxic Diarylheptanoid from Amomum tsao-ko Fruits
Moon, Surk-Sik,Cho, Soon-Chang,Lee, Ji-Young Korean Chemical Society 2005 Bulletin of the Korean Chemical Society Vol.26 No.3
The crude methanol extract of the fruits of Amomum tsao-ko (Zingiberaceae) showed cytotoxic activity. Bioactivity-guided separation led to the isolation of a diarylheptanoid, tsaokoarylone [7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one] (2). 2 showed cytotoxicity at 4.9 and 11.4 $\mu$g/mL ($IC_{50}$) against human nonsmall cell lung cancer A549 and human melanoma SK-Mel-2, respectively, determined by SRB colorimetric method. During purification-(4-hydroxyphenyl)-4-hydroxyhexan-2-one (4) together with three known diarylheptanoids was also isolated. Their structures were determined from interpretation of spectroscopic data (IR, UV, MS, and NMR) and synthesis confirmed the structure of 2.
Effects of Exercise Programs on Cancer Patients: a Systematic Literature Review
( Eun-surk Yi ),( Sang-wan Chun ),( Ji-youn Kim ) 융합연구학회 2017 융합연구학회지 Vol.1 No.1
This study examined exercise programs for the cancer patients, patient exercise time, and the data on exercise programs according to the type of cancer by systematically reviewing the results of the experimental studies on the application and effectiveness of the exercise programs for the cancer patients registered with the Korean Citation Index (KCI) and published between January 2010 and December 2016. The study result showed that exercise programs for the Korean cancer patients were found to have a positive effect. The most common cancer type and program time were ‘breast cancer patients’ and ‘after surgery’. Exercise programs were confirmed to be used in the recovery period. It was also confirmed that studies on the exercise programs for the cancer patients are very limited even though exercising has a positive effect on physical function and psychology during cancer treatment. Since the effectiveness of the exercises has been proven, it is necessary to develop various exercise programs based on the type of cancer and treatment period, and study the application of exercises in the field.