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      • AHCISCOPUSKCI등재
      • KCI등재

        신수혈의 침자극과 황기약침이 실험용 생쥐의 면역활성물질인 IL-1 α의 遺傳子發現에 미치는 影響

        申相習,朴元煥,洪文燁,李泰均,崔達永 대한동의병리학회 1999 동의생리병리학회지 Vol.13 No.2

        체내의 환경을 항상적으로 유지하는 생체방어체계에는 면역활성물질이 있으며, 이러한 면역활성물질의 적절한 발현이 생체의 항상성을 유지하는데 작용하게 된다. 이에 한의학에서는 생체의 항상성 유지와 체내의 면역력 증가를 위해 많은 요법들이 시행되어 왔는데, 그 중 자침요법과 약침요법이 많이 응용되고 있다. 그러나 침자극과 약침의 효과에 대한 기전은 기대하는 만큼 제시되지 못하고 있다. 이에 본 논문은 침자극과 약침의 효과에 대한 기전을 밝히는 방법의 일환으로서 면역활성물질인 IL-1α가 補腎臟, 振氣化, 祛水濕, 强腰脊, 益水壯火 등의 穴性이 있는 신수혈(BL23)의 침자극과 황기약침처치를 통해 어떻게 발현하는가를 관찰하였다. 그 결과, 면역 증강 작용을 나타내는 cytokine IL-1α 에 대한 침자극의 반응은 관찰되었고, 황기약침에 의한 IL-1α 의 발현은 명확하지 않았다. 그러므로 신수혈을 이용한 cytokine IL-1α의 추적은 황기약침의 효과보다 침자극의 효과에 대한 근거를 추측할 수 있을 것이며, 뿐만 아니라 침자극에 의한 면역반응정도를 통해 질병의 진행상태를 나타내는 진단지표로서 활용가능성이 있을 것이다. Acupuncture and Radix Astragali aqua-acupuncture stimuli have long been used to cure human diseases. However, it still remains to be unknown on its action mechanism, physiological and biochemical aspects. Thus, many attempts were made to show the scientific background covering the above mentioned mechanisms. Most recent studies show that these tests improve blood circulatory system and increase leucocyte counts. In this study, we have applied the acupuncture stimuli to mouse Sinsu(BL23), which is a stimulative point of oriental medicine, to see if cytokine such as IL-1α can be detected. Mice were treated with lipopolysaccharide(LPS) for inflammation induction, and then reverse transcriptase-polymerase chain reaction (RT-PCR) using each primer set was performed to trace the amounts of mRNA. The results are as follows ; 1. The RT-PCR product using IL-1α primers was detected as 450 bp on agarose gels and the IL-1α gene was not expressed in normal mice at 15 min after the removal of acupuncture. However, it was gradually increased indicating a faint expression after 30 min. 2. IL-1α was expressed in LPS-treated mice 30 min after the acupuncture was pulled out, and expressed most highly at 3 h after the removal of acupuncture. The gene expression of LPS-treated mice were more effective than those of normal mice. 3. IL-1α was not expressed in normal mice and LPS-treated mice from 30 min to 3hs. after Radix Astragali aqua-acupuncture stimulation. Therefore, a tracing the gene expression of cytokine IL-1α can be used more not only for a basis of the effect of acupuncture stimulation but a diagnosis guide through the immunological action than the effect of Radix Astragali aqua-acupuncture. Moreover, we need to further study the cytokine's expression in Radix Astragali aqua-acupuncture stimulation.

      • KCI등재

        식품 기호가 성인의 건강상태에 미치는 영향 : 익산시를 중심으로

        신미경,한성희 동아시아식생활학회 1997 동아시아식생활학회지 Vol.7 No.2

        The purpose of this study was to investigated relationship between heath status and food prefer of male and fermale adults who live in Iksan City, Cheonbuk, Korea. The subjects consisted of 96 male and 93 fermale adults were aged 20 to 70 years old. Each subject was interviewed to get information of food preference. Blood samples were taken concentration of serum in hemoglobin, glucose, total cholesterol, GOT(glutanric oxaloacetic transaminase), GPT(glutamic pyruvic transaminase) were measured. The results obtained were as follows: Among the food preference were like, dislike and ordinary answered to male and fermale adults the normal average of serum concentration with hemoglobin level showed 15.4, 14.2, 15.5, 12.9, 15.8 and 13.2g/dl, glucose level showed 85.8, 86.1, 87.5, 88.1, 87.9 and 86.1㎎/dl, total cholesterol level showed 183.1, 185.0, 172.4, 193.5, 181.2 and 184.0㎎/dl, GOT level showed 4.8, 23.4, 24.8, 23.9, 24.9 and 21.7ppm, GPT level showed 22.7, 20.2, 26.3, 18.5, 22.5 and 18.4ppm respectively. The abnormal average of serum concentration with hemoglobin level showed 11.1, 10.8, 12.2, 11.3, 12.5 and 11.0g/dl, abnormal glucose level showed 155.7 168.5, 166.2, 134.1, 124.1, 130.1, abnormal total cholesterol level showed 260.3, 273.7, 255.2, 286.5, 255.9 and 251.8㎎/dl, abnormal GOT level showed 58.8, 66.8, 51.8, 50.3, 51.2 and 51.0ppm abnormal GPT level showed 54.3, 48.6, 51.3, 50.2, 53.2 and 45.5ppm respectively.

      • KCI등재

        계층적 인력구조를 갖는 연구기관의 인력계획 모형

        신상은,김영호 한국경영과학회 1991 經營 科學 Vol.8 No.2

        The purpose of this thesis is to develop the methodology of manpower planning model which can forecast aggregate manpower and allocate manpower in organization level. This model consists of aggregate manpower planning model and manpower allocating model;Firs model applied Multiple Regression Analysis with the given project budget data, Second model applied Markv Chain Model to datermine recruiting plans and to forecast the hierachy of researcher. This model provides proper method of manpower planning and help to solve the managerial problem for manpower police.

      • 언어학습을 위한 전자 사전 관리 시스템 구현

        신민화,양호원,배상현 조선대학교 전자정보통신연구소 2002 電子情報通信硏究所論文誌 Vol.5 No.1

        Due to the rapid development and growth of users of internet, a lot of remote systems for language studys, Which are the applications of web technology are appearing. For remote systems for language studys, on-line electronic dictionary which allows searching for particular words is on important sector among many methods to enhance the effect studying. In this paper for the manage of language studys to easily many sector and manage the electronic dictionary, we are trying to suggest management system which complement the language studys.

      • KCI등재
      • 경동맥분지관 모형내 유동현상의 연구

        유상신,서상호,정태섭 한국항공대학교 1996 論文集 Vol.34 No.-

        경동맥분지부내 혈액유동을 촬영하는 자기공명혈관촬영술은 경동맥외벽을 따라 발생되는 신호소실로 인하여 때로는 실제 혈류현상을 잘 나타내지 못한다. 본 연구에서는 경동맥분지부에서 신호소실의 원인이 되는 유동의 역류 현상을 실험 및 수치해석적 방법으로 연구하고자 한다. 실험은 생체용 수지로 만든 경공맥분지관의 보형을 이용하고 유동형태는 4w% 설탕수용액으로 채워진 재순환장치에 설치된 모형에서 자기공명혈관촬영술과 색혈류영상장치를 이용하여 관찰하였다. 수치해석을 위한 경동맥의 이상화된 기하학적 형상은 제작된 모형과 동일하게 하였다. 정상상태의 운동량방정식을 유한체적법으로 수치해를 구하였다. 자기공명촬영술과 색혈류영상장치로 관찰한 모형내 유동현상은 수치 해석결과와 잘 일치한다. Magnetic resonance angiograms for blood flows in the carotid artery bifurcation sometimes fail to exhibit the real flow phenomena due to the signal dropout phenomenon along the posterior wall of carotid sinus where the reversal flow prevails. The objective of this study is to investigate the flow reversal phenomenon in the carotid artery. A phantom of the carotid bifurcation made of bioacrylic resin is used to observe the flow phenomena in the carotid artery. Flow patterns are observed by using magnetic resonance angiogram and color Doppler imaging systems for flows in the phantom of an automatic closed-type circulatory system filled with sugar 4 weight percent solution. For numerical analysis the idealized geometric shape of the carotid artery is constructed to portray the phantom. Steady momentum equation is solved by the finite volume method. Results of numerical analysis are compared with those of magnetic resonance angiograms and color Doppler images. The flow phenomena observed in the phantom on magnetic resonance angiogram and color Doppler imaging are identical to those of the numerical results.

      • KCI등재

        공급률 및 탈곡통 길이 변화에 따른 자탈형 콤바인 탈곡 성능

        서신원,이상우,허윤근 충남대학교 농업과학연구소 2006 농업과학연구 Vol.33 No.2

        Threshing loss was increased due to dropping of the threshing efficiency when the 4 row head-feed combine harvested 5 row rice to improve harvesting performance of a combine. Reasonable design criteria were examined to determine the ranges of both of feed rate and the length of threshing drum for the 4 row head-feed combine being used as a 5-row combine. Harvesting performance increased as working width or working speed increased, it resulted in 15% increase when the working width increased from4 row to 5 row. Harvesting operations of the 4 row combine performed normally in the 4 row rice in threshing loss less than 1%, however, threshing loss increased to 2.25% in the 5 row due to poor threshing efficiency. The length of threshing drum was increased from 710 mm to 810 mm as well as the speed of crop feed chain was increased from 0.61 m/s to 0.75 m/s so as to improve the poor threshing efficiency resulted from the enlarged working width from the 4 row to the 5 row, which would decrease threshing loss less than 1%.

      • 멀티미디어에 적용된 워터마크 기술들의 개관

        이신주,정성환 한국산업정보응용수학회 2001 한국산업정보응용수학회 Vol.5 No.1

        In the early days, encryption and control access techniques were used to protect the ownership of media. Recently, the watermark techniques are utilized to keep the copyright of media. Digital watermarking, a concept of embedding a special pattern. uses an algorithm of inserting a watermark to protect the copyright of media. It has recently become important in various application areas. The various watermark techniques have been proposed by many authors in the last several years. However, there are not enough analysis and comparison on the previous researches. In this paper, for the understanding of the previous works and for the future related research, we try to classify and analyze the conventional watermark techniques from the various points of view. Currently watermark techniques based on the transfer domain, are more popular than those of the spatial domain. DCT-based methods have been most widely used among the transform based methods. However, recently wavelet-based watermark techniques are becoming main research topic. With wide use of internet, effective audio and video watermarking researches are also required.

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