結核性 乳腺炎의 一例

鮮于鍈,崔至源,李英麟 醫藥係社 1965 綜合 醫學 Vol.10 No.4

대추나무의 開化特性에 關한 硏究

鄭仙英,劉永山 대구효성가톨릭대학교 1994 연구논문집 Vol.49 No.1

대추의 結實安定윽 위한 墓礎 硏究로써 무등과 복조品種를 팡시하여 대추꽃의 형태적특성과 開花時期, 開花時刻,開花段階 및 柱頭의 receptivity등을 硏究 調査하여 다음의 結果를 얻었다. 대추꽃은 花器構造가 특이하여 꽃받침과 화반이 發達되고 꽃잎은 退化되어 있었다. 小花의 開化過程은 7段階로 子분되었으며 꽃받침이 수평으로 展開되는 4段階를 完全開花로 보았다. 대추꽃은 11∼12時부터 꽃봉오리가 열개되어 2시경에 開花最盛期를 보였으며 氣溫과 일조시수에따라 開花時刻이 多少 變化되었다. 開葯은 꽃잎에서 수술이 分離됨과 同時에 일어났으며 화사의 탄력과 訪花昆蟲에의해 受粉이 이루어졌다. 開葯時 花粉 發芽率은 60%이상이었으나 時間이 經過함에 따라 점차 감소되어 18시간이후에는 6%에 불과하였다. 柱頭上에 受粉된 花粉은 수분후 12시간 이후부터 發芽되기 시작하여 24시간까지 發芽率이 擔加되었고 柱頭上의 花粉發芽率은 開花當日이 가장 높았다. This experiment was conducted to investigate the floral morphological characteristics and their flowering habits such as flowering duration, opening time of day, flowering stage and stigma receptivity with 'Moodeung' and 'Bokjo' Chinese jujubes during blooming period. The results were as follows : Sepal and disc are specially developed but petal degenerated in florets of cyme inflorescence. Jujube trees showed very long blooming period and the flowering continued during about 55-60day until middle of August. Anthesis was completed between 12:00 and 4:00 PM in the used jujube cultivars and flowering stage was divided into seven stages. Flowering time of day was changed by atmospheric conditions such as temperature,sunshing hours. Anther dehiscence started on the time when the stamens emerged from petal and then pollens were rapidly transfered by pollinator. But unless disturbed pollen grains were sticky and remained on the anther. Percentage of pollen germination showed over 60% shortly after anther dehiscence, But it was gradually decreased and then was only 6% in 18 hours after anther dehiscence. Germination of pollen grains on stigma began from 12 hours after pollination and the receptivity of stigma showed high during 4 hours after anthesis.

탄광부 진폐증의 운동지수

조영선,김세곤,문우기,유재인,정치경 가톨릭대학 산업의학 센타 산업의학연구소 1984 韓國의 産業醫學 Vol.23 No.3

Exercise index(EI) was measured on 933 pneumoconiosis patients (865 patients with small rounded opacities and 68 patients with large opacities) and 176 suspected pneumoconiosis patients from Korean anthracitic mines, in order to evaluate the ventilatory impairment of pulmonary function according to the chest radiographic findings of pneumoconiosis. Exercise index was obtained from the maximum breathing capacity (MBC) and the exercise ventilation volume(EV) which were measured by spirometer and two step-test. Classification of pneumoconiosis was based on the international classification of ILO U/C. The results were as follows: 1. The mean value of E1 was significantly increased in pneumoconiosis patients with large opacities(46.0%) than in patients with small rounded opacities(26.5%) and with suspected pneumoconiosis(25.0%). The number of jpatients in substandard EI was 97.1% in patients with large opacities but 49.4% in patients with small rounded opacities and 40.3% in patients with suspected pneumoconiosis. 2. The mean values of EI and the number of patients in substandard EI were markedly increased in pneumoconiosis patients with small rounded opacities and suspected over 50 years of age. However, the number of patients in substandard EI showed no association with age in pneumoconiosis patients with large opacitis. 3. In pneumoconiosis patients with small rounded opacities, the mean values of EI and the number of patients in substandard EI showed significant association with the profusion (category) but no significant association with the type of small rounded opacities. 4. In pneumoconiosis patients with large opacities, the mean values of EI and the number of patients in substandard EI showed no significant difference between patients complicated with and without pulmonary tuberculosis. 5. No significant association of EI and the number of patients in substandard EI with the size of large opacities was observed in pneumoconiosis patients with large opacities, however, the mean values of EI showed increasing tendenccy in category B and C compared to category A.

두꺼운 홀로그램격자의 회절효율 계산

김태영,김선일 釜山工業大學校 1985 論文集 Vol.27 No.-

A thick uniform hologram grating was alanyzed using coupled-wave theory and its diffraction efficiency was calculated. The diffraction efficiency of a thick attenuated hologram grating was calculated. Obtained diffraction efficiency was discussed for some special cases.

韓國人의 遺傳學的硏究 : 數個地方에 있어서의 人口動態에 關하여

姜永善,趙完圭 서울대학교 1957 서울대학교 論文集 Vol.5 No.-

On Korean population, authors have investigated some vital statistics which are varied by the hereditary factors. 1) Birth rate and Death rate In Seoul, the death rate is higher than birth rate, in Island Jeju, however, the former shows that is slightly lower than the latter, and in Island Ulnung the birth rate is higher. In Seoul this phenomenum is of the urban type, and in Island Ulnung because the sample is too smal size to discuss, it may not be assumed steadily as the perfact proportion. 2) Sex-ratio at birth That more boys than girls are born with the numerically superiority have been hown in every nation or race by the researches of human population at the past. In Korea, it might say that is of one of the highest ratio among the world. From this calculation, it is also much like as past statistics, that is, more boys than girls are born, it's ratio is 113.50 with the data collected in present work. 3) Sex-ratio of the twins Authors have take 205 pairs of twin(175 pairs in Seoul and 30 pairs in Island Jeju) as the examples the rate of the constitution of twins is of 3.oo:1.oo:2.30 to two males:one male and one female two females respectively. The rate of the identical twins is estimated as 67.8% to fraternal twins, and the sex-ratio is 12162. 4) Frequency of the cousin marriages With the data collected in this investigation, in Seoul, the frequency of the cousin mariages is measured as 7.81%, and in Island Jeju 5.59% of total marriages had occured. These rates are higher comparing with the other nations.

防己황기탕 및 枸杞子가 肥滿白鼠의 體重에 미치는 影響

宋勇善 圓光大學校 韓醫學硏究所 1992 원광한의학 Vol.2 No.1

This study was designed to investigate the effects of Bangkihwangkitang(방기황기탕), Bangkihwangkitang with Lycii frucuts and Lycii fructus on the weight of obese rats. A series of experiments have been conducted in order to measure the effects of the above materials on the weight, organs and serum. The measurements have been performed on ; (1) the weight of liver, spleen, kidneys, adrenal and pituitary; (2) the quantity of total cholesterol, tryglyceride, free fatty acid, total lipid, T_3, T_4, T_3 uptake, free T_3 and free T_4 in serum ; and (3) the quantity of total lipid in feces. The results are : 1. It was significantly proved that Bangkihwangkitang, Bangkihwangkitang with Lycii fructus and Lycii fructus decreased the weight of the obese rats as time passing. 2. It was not shown that Bangkihwangkitang Bangkihwangkitang with Lucii fructus and Lycii fructus had impacts on the weight of liver, spleen, kidneys, adrenal and pituitary. 3. Bangkihwangkitang Bangkihwangkitang with Lucii fructus and Lycii fructus significantly inhibited the increase of the quantity of total cholesterol, tryglyceride, free fatty acid and total lipid in serum. 4. Bangkihwangkitang and Lycii fructus significantly increased the quantity of T_3, T_4, T_3 uptake, free T_3 and free T_4 in serum of obese rats. 5. Bangkihwangkitang with Lycii fructus increased the quantity of T_3, T_4, T_3 uptake, free T_3 and free T_4, in serum of obese rats. The tests of significance proved significant for all these contents except T_3. 6. Bangkihwangkitang, Bangkihwangkitang with Lycii fructus and Lycii fructus did not affect the change of the quantity of total lipid in feces. Based on the results, it is concluded that the clinical application of Bangkihwangkitang, Bangkihwangkitang with Lycii fructus and Lycii fructus can help cure obesity.

內臟轉錯症隨伴 左心症 : 合倂 大血管轉錯症에 對한 手術 1例 Levocardia with Situs Inversus Viscerum:A complicated combination of anomalies

李寧均,朴鍾善,崔秉茂,金升煥,洪彰義,姜錫麟 中央醫學社 1963 中央醫學 Vol.5 No.5

A six years old Korean girl was admitted in February 1963, with cyanotic congenital heart disease. By auscultation grade I -Ⅱ systolic murmur was audible along the left sternal border without thrill. Remarkable laboratory findings were high degree of and hematuria, polycythemia, albuminuria, and right sided hemiparesis. Transposition of the abdominal viscera with levocardia was found on routine X-ray study ECG showed right axis deviation and inverted P-wave in lead I . The right heart catheterization and angiocardiography with Shonander serial X-ray machine showed the right-sided (venous)atrium receiving the right and left superior vena cava separately, complete transposition of the great vessels, shunt at the ventricular level, and pulmonary stenosis. The inferior vena cava coursed along the left border of the spinal column and drained into the venous atrium, which is in the left hemithorax. The aortic arch was left-sided and bifurcated right ureter was visualized. Glenn' s procedure was done to increase the pulmonary blood flow in March 1963. Postoperative course was benign and uneventful. The follow-up study of the case, five month postively, revealed satisfactory results; increased exercise tolerance, marked relief from dyspnea on exertion, abolished cyanosis on rest, incresed arterial oxygen saturation (from 48% to 70%), normalization of hemogram, and increased pulmonary vascularity on the right lung field. The final anatomical findings of this unusually complicated cardiac anomaly were: (1) Levocardia with situs inversus viscerum, chamber inversion, and inverted P-wave in Lead I on ECG. (2) Transposition of the great vessels with pulmonary stenosis. (3) Intra-cardiac shunt or Shunts: i. Undetermined intracardiac shunt, Vntricular septal defect or single vent -ricle or atrioventricularis communis ? ii. Confirmed atrial septal defect. (4) Double superior vena cavae: left superior vena cava drained into the right atrial cavity (right atrium proper or coronary sinus?). Inferior vena cava on the left side. (By course of the cardiac catheter) Left aortic arch and left descending aorta. Bifurcated right ureter. Asplenia :presence not determined. Three lobes of the right lung confirmed by operation but numbr of lobes on the left lung undetermined. This report is believed to be the first operative palliation case of complete trans-position of the great vessels with pulmonary stenosis in a Korean literature.

대후두공을 기준으로 한 뇌교와 소뇌편도의 정상위치 : 자기 공명영상을 이용한 계측

최순섭,이영일,정덕환 동아대학교의과대학 1992 동아의대학술지 Vol.4 No.1

국내 Human Immunodeficiency Virus(HIV) 감염자와 정상인의 면역학적 표지인자 비교연구

신영오,류재천,최병선,박용근 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCINE 1995 Journal of biomedical laboratory sciences Vol.1 No.1

HIV감염자는 질병의 진전에 무관하게 감염 후의 경과시기에 따라서 CD4 T림프세포등 각종 면역상태를 나타내는 표지가 변한다. 따라서 HIV감염자의 질병진전을 예보하기 위하여서는 정기적으로 CD4등 각종표지를 측정하여 감염자의 질병상태를 monitoring하게 된다. 그러나 이러한 수치를 감염자관리에 적용하기 위하여서는 우리나라 일반인의 정상치를 파악하여 이를 지표로 해야하므로 국내정상인의 각종면역치에 대한 조사가 요구된다. 현재의 기준으로는 500이하로 떨어질 때에는 예방차원에서 AZT를 복용하게 되며 200이하로 떨어지면 질병의 유무에 관계없이 환자로 관리하게 된다. 본연구에서는 한국인 185명의 감염자와 140명의 비감염자에 대하여 정기적으로 CD4 및 CD8T 림프세포와 CD4/CD8비를 측정하였다. 시험은 Flow cytometer(Facstar)를 이용하여 각각의 CD 분자에 대한 모노크로날 항체를 이용하여 2중혈광색소염색방법으로 측정하였다. HIV감염자의 CD4-T림프세로 절대수 및 백분율은 각각 462 및 18.2%이었는 반면, CD8의 수치는 1,170 및 47.0%이었다. 또한 CD4/CD8비는 0.43이었다. 이와는 대조적으로 비감염자의 경우, 한국인의 CD4의 평균세포수는 886, 백분율은 32.9%이었으며, CD8 세포수는 730, 백분율은 26.8 그리고 CD4/CD8비는 1.31이었다. 외국인과 한국인과의 면역지표수치를 비교하였을 때에 CD4세포수와 백분율, CD8의 백분율에서는 현저한 차이가 없었으나 외국인 비감염자의 경우 CD4백분율이 43.6%, CD8 T림프세포의 절대수가 560으로 한국인과 약간의 차이가 있었다. 따라서 HIV감염자관리를 위한 면역지표측정시험에서의 각종수치의 정확한 해석을 위하여서는 한국인 비감염자수치를 고려해야할 것으로 판단된다. Several studies showed that the immunological factors such as CD4+ cell number, CD4%, CD8+ cell number and CD4/CD8 ratio and the serological factors such as β²-microglobulin(β²-MG), neopterin, soluble CD4, and soluble CD8 are related to the risk of development of AIDS. Especially, the CD4+ cell counts have been used to monitor progresson of HIV disease, to stratify, and to follow patients in clinical trials. Recently, the Centers for Disease Control and Prevention(CDCP) in USA has made the CD4+ cell count as a part of the classification of HIV disease. It is composed of 3 categories such as 1, 2, and 3 which asr ≥500/㎣, 200/㎣ ≥and <500/㎣, and < 200/㎣, respectively. In this study, to estimate the differences of immunological factors between HIV-infected and normal human groups in Korea, CD4+ T and CD8+ T cells, and the CD4/CD8 ratio were measured in 185 HIV-infected subjects and 140 healthy adult subjects. The lymphocyte subsets such as CD4+ T and CD8+ T were analysed by flow cytometer(FACStar) with two-color immunofluorescent stain using monoclonal antibodies such as anti-CD4 and anti-CD8 antibodies. The absolute numbers and percentages of CD4+ T and CD8+ T and the CD4/CD8 ratio of HIV infected persons were 462±277/㎣, 18.2±7.7%, 1,170±534/㎣, 47.0±10.6% and 0.43±0.26 whereas those of uninfected persons were 886±299/㎣, 32.9±7.0%, 730± 259/㎣, 26.8±6.4% and l.31±0.46(P<0.01). In addition, estimating the reference values of peripheral blood lymphocyte subsets of Korean, the absolute numbers and percentages of CD4+ T and CD8+ T and the CD4/CD8 ratio of 140 healthy adults persons were measured and compared with those of foreigners. The reference ranges of CD4+ T cells, CD8+ T cells, CD4%, CD8%, and the CD4/CD8 ratio and 1.31t0.46, respectively. The significant differences were not observed when compared with those of foreigners. However a little difference was observed in the percentages of CD4+ T and the absolute numbers of CD8+ T between the normal values of Korean and those of foreigners were 43.6±8.9%, 560±230/㎣. This result can also be useful as a basic data for the treatment and surveillance of HIV-infected patients in Korea.

New Zealand White 토끼의 생식세포 및 체세포 분열에 의한 염색체 분석

신선희,김희수,최영현,이원호 부산대학교 유전공학연구소 2001 분자생물학 연구보 Vol.17 No.-

토끼(New Zealand White rabbit)의 감수분열 및 유사분령상을 통해 그 염색체적 특징을 조사하였다. 감수분열 염색체의 표본 작성은 공기건조법을 다소 변형하여 사용하였고, 유사분열 중기상의 핵형분석에는 G-분염법을 이용하여 다음과 같은 결과를 얻었다. 1. 제1감수분열의 접합기와 태사기의 염색소립과 sex vesicles 및 동원체가 뚜렷하게 구별되었다. 태사기의 중기에서부터 후기 과정이 진행되는 동안에 2가염색체에서 측면으로 돌출한 머리카락 모양의 돌기들이 관찰되어졌고, 이 돌기들은 염색체가 lampbrush 염색체 구조의 모양이 되도록 해주었다. 이동기의 염색체들은 키아즈마의 수와 위치에 따라 분류가 가능하였다. 제1 감수분열 전기의 후반부 과정과 중기Ⅰ 시기에는 2가염색체로 된 21개의 상염색체와 1개의 말단결합으로 연결된 X-Y 염색체를 관찰할 수 있었다. 2. New Zealand White rabbit의 생식세포에서 관찰된 2가 염색체의 형태는 1CH, 1TAl 및 2TA 2가염색체 유형이 대부분을 이루었다. New Zealand White rabbit에서의 평균 키아즈마 빈도는 약 30.2로 나타났으며, 키아즈마 빈도가 복사기, 이동기 및 중기Ⅰ로 분열이 진행됨에 따라 다소 감소하는 경향이 있었다. 3. New Zealand White rabbit의 핵형분석에 의하면 염색체 수는 44개(2n=44)로서, 8쌍의 중부염색체, 9쌍의 차중부염색체, 4쌍의 단부염색체로 된 21쌍의 상염색체와 중부염색체인 1개의 X 염색체 및 단부염색체인 1개의 Y 염색체로 구성되어 있음을 알 수 있었다. Chromosomal characteristics of New Zealand White rabbit was studied at meiosis and mitosis. The meiotic chromosomal preparations were made with the modified air-drying method and karyotype analysis was performed with the G-banding technique, using isolated mitotic metaphase chromosomes of the New Zealand White rabbit. Chromosomes, sex vesicles and centromeres could be could be classified in the zygotene and the pachytene of the meiosis Ⅰ. The hair-like processes projecting laterally from the axes of bivalent chromosomes at the mid-late pachytene were basis of the numbers and the locations of chiasma in the diakinesis. Twenty-one autosomal bivalents and a single unequal terminally associated X-Y bivalent were observed during the late prophase and the metaphase of the meiosis Ⅰ. Most of the bivalent types observed in the New Zealand White rabbit spermatocytes were 1CH, 1TAl, and 2TA bivalents. The mean chiasma frequency (CE) of the male New Zealand White rabbit was 30.2, and it was found that the CF value tended to decrease through the diakinesis and the metaphase Ⅰ. The karyotype of the New Zealand White rabbit was a male chromosome number of 44(2n=44), comprising 8 pairs of metacentric, 9 pairs of submetacentric, 4 pairs of acrocentric autosomes, metacentric X chromosome and acrocentric Y chromosome.