A survey of knowledge and behavior regarding skin cancer.

( Young Bin Shin ),( Jeong Won Jo ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: The recognition of prevention and early detection of skin cancer has been increased more than before. Although skin cancer is not rare, most patients are little known about general awareness of skin cancer. Objectives: In this study, we survey the awareness and knowledge of skin cancer and sun protection behavior among South-Gyeongnam province. Methods: We reviewed a written questionnaire and patients’ self-checked records including patients’ basic medical information and knowledge of skin cancer protective modalities. Results: In total 284 subjects (94.7%(284/300), 67%(190/284) females, mean age 57.4 years) completed the survey. Most people (77.5%, 220/284) knew that the sun was most dangerous for their skin but relatively large portion of them (42.7%, 94/220) had no action to protective attitude like sun screen, large hat and gloves. Conclusion: The results show that many participants had known necessity of skin cancer prevention and importance of early detection, but didn’t have had any protective action. Therefore, a more effective skin cancer education and prevention program is needed. We suggest that the measurement of effects of a multimodal educational intervention on knowledge of sun protection practices and engagement in self sun-protection behaviors also need to be check.

노인의 대체요법 이용 양상에 대한 조사연구

신경림,박선영,신수진 성인간호학회 2004 성인간호학회지 Vol.16 No.1

Purpose: The purpose of this study was to describe the using pattern of alternative therapies in the elderly. Method: 197 subjects, persons who were more than 60 years old, we interviewed. We modified and complemented Shin's(2000) instrument in accordance with purpose of this study. Data were analyzed statistically by using SAS program. Result: 1. It was shown that 66.84% of subjects have utilized one or more types of alternative therapy. 2. It was shown that the most frequently used types are acupuncture (48.83%), and ethmoid bone therapy (42.75%). 3. Acupuncture was shown to be the most satisfactory type of therapy (14.50%). 4. There was a significant difference in the use ratio by sex; female 73.47% and male 60.20%. 5. Among users of alternative therapies, the most frequent responses to each question were as follows: 1. Motive of Use - "for complete cure of symptoms" (32.31%). 2. Side effects - "no side effects" (95.97%). Conclusion: We found that elderly persons used alternative therapies more frequently than others perpulations. Diet therapy and Hand therapy were most commonly used in older people. Although the elderly use alternative therapy, they cannot place confidence in its scientific reliability. Therefore, we need to examine the effects of alternative therapy.

The Efficacy and Safety of 4-n-butylresorcinol 0.1% Cream for the Treatment of Melasma: A Randomized Controlled Split-face Trial

( Sun Young Huh ),( Jung Won Shin ),( Jung Im Na ),( Chang Hun Huh ),( Sang Woong Youn ),( Kyoung Chan Park ) 대한피부과학회 2010 Annals of Dermatology Vol.22 No.1

Background: Melasma is a common acquired symmetrical hypermelanosis that occurs on sun-exposed areas, and it is frequently observed among women. Various treatment modalities have been tried, but none are completely satisfactory. 4-n-butylresorcinol, which is a resorcinol derivative that has an inhibitory effect on both tyrosinase and tyrosinase-related protein-1, was introduced in 1995 and it has received increasing attention as a new hypopigmenting agent. However, the hypopigmenting effect of 4-n-butylresorcinol in human subjects has only been shown in a few studies. Objective: The aim of this study was to investigate the hypopigmenting efficacy and safety of 4-n-butylresorcinol 0.1% cream for the treatment of melasma. Methods: Twenty patients with melasma were enrolled to this randomized, double-blind, vehicle-controlled, split-face comparative study. The patients were instructed to apply 4-n-butylresorcinol 0.1% cream or vehicle to each side of the face twice daily for 8 weeks. Mexameter measurements were performed along with photography at baseline, 4 weeks and 8 weeks. Adverse events were observed and recorded throughout the study. Results: All the patients completed the study. Mexameter measurements demonstrated that the melanin index of the treated side showed a significant decrease when compared with that of the vehicle-treated side after 4 weeks (p=0.006) and after 8 weeks (p<0.0005). All the adverse reactions were mild and transient. Conclusion: 4-n-butylresorcinol 0.1% cream showed rapid efficacy and it was well tolerated when used for the treatment of melasma. (Ann Dermatol 22(1) 21∼25, 2010)

정신분열병에 대한 Risperidone의 효과 및 안전성에 관하여

신석철,왕성근,지익성,이선우,이규광,이봉희,이진영,황선희,신용재,배경도,김정란 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

In order to evaluate the efficacy and safety of risperidone, 10 patients with chronic schizophrenia were examined for 8 weeks in a silgle-open study. After the wash-out period of 1 week, risperidone was administered. Efficacy was evaluated by means of Positive and Negative syndrome Scale for Schizophernia(PANSS) and Clinical Global Impression(CGI). Safety assessment included the Extrapyramidal Symptom Rating Scale(ESRS), vital signs, body weight, ECG, and laboratory tests. The results were as follows 1) On the PANSS total score, there was significant improvement of total score after 1 week (P<.05) of administratiom. 2) On the PANSS positive and negative subscal, there were significant improvement of posotive and negative scores after 2 weeks (P<.05) of administration. 3) On the PANSS general psychopatholgy subscals, there were significant improvement of general psychopathologyscores after 1 week (P<.05) of administratiom. 4) On the CGI, there was significant decreasement of clinical impression of severity of schizophrenia score after 2 week (P<.05) of administration. 5) A statistically significant increase in body weight (P<.05) was observed after 8 weeks of administration. 6) EPS reached the peak at the end of the 1st week of administration of risperidone (11.8± 24.25) but they were easily relieved by addition of benztropine and clonazepam. There was not significant change in laboratory tests, vital sign, ECG after 8 weeks of administration. These results suggest that Risperidone is an effective antipsychotics and clinically safe except for increased body weight in chronic schizophrenia.

Voice Mismatch Meets Neurolinguistics

Gui-Sun Moon,Sun-Woong Kim,Jeong-Ah Shin,Hae-Kyung Wee,Jong Un Park,Myung-Kwan Park,Wonil Chung 현대문법학회 2018 현대문법연구 Vol.99 No.-

Gui-Sun Moon, Sun-Woong Kim, Jeong-Ah Shin, Hae-Kyung Wee, Jong Un Park, Myung-Kwan Park, and Wonil Chung. 2018. Voice Mismatch Meets Neurolinguistics. Studies in Modern Grammar 99, 85-115. This paper aims to investigate Korean advanced L2 English learners’ strategies for ellipsis resolution during sentence processing. Ellipsis resolution is known to involve several stages of information processing from the initial step of detecting an ellipsis-licensing element by the parser to the final stage of integrating the ellipsis site with the information retrieved from the antecedent of the ellipsis site. In examining these steps, we have manipulated three factors: (i) TP vs. VP-ellipsis; (ii) two types of discourse coherence relations (resemblance(-contrast) vs. cause-effect relations); (iii) voice match vs. mismatch. We found through the ERP recordings that voice mismatch in TP ellipsis elicited N400, followed by P600, irrespective of discourse coherence relations. In contrast, voice mismatch in VP-ellipsis registered N400 only in resemblance(-contrast) relation, but not in cause-effect relation. These findings lead us to conclude that Korean advanced L2 learners of English seem to undergo the full sequence of processing stages required for ellipsis resolution.

The Effects of Modified English Text on Reading Comprehension by Korean University Students

Shin, Jung-Sun 이화여자대학교 사범대학 교과교육연구소 2006 교과교육학연구 Vol.10 No.1

외국어를 가르칠 때 학습자의 수준에 따라서 외국어 교재를 어떻게 수정(또는 조정)하는 것이 가장 효과적인지에 대한 연구가 최근 활발히 이루어지고 있다. 현재까지의 연구에서 밝혀진 바에 따르면 성인 학습자의 경우 외국어 문장들의 단순화(simplification)보다는 상세화(elaboration)가 학습자의 이해를 더욱 돕는 것으로 알려져 왔다. 본 논문에서는 어떠한 유형의 수정된 영어 교재가 우리나라 대학생들, 특히 영어 능력이 별로 높지 않은 대학생들의 독해 이해력을 돕는지를 실험을 통하여 알아보았다. 이를 통하여 영어 능력 하위 단계의 성인 학습자에게도 상세화한 영어 입력이 더욱 효과적인지를 검증하고자 하였다. 본 논문의 실험을 위하여 139명의 C 대학교 학생들을 세 집단으로 나누어 각 집단의 영어 능력 검증을 통하여 세 집단의 동질성을 확인하였다. 이후 각각의 집단에게 수정을 가하지 않은 영어 원문, 단순화한 글, 상세화한 글을 제시하여 읽게 한 후 독해 이해력 시험과 이해도에 관한 설문 조사를 실시하여 다음과 같은 결과를 얻었다. 첫째, 본 실험 대상 집단 중 단순화한 영어 글을 읽은 집단이 독해 이해 시험에서 가장 높은 평균 점수를 보였으며 상세화한 영어 글을 읽은 집단이 가장 낮은 점수를 보였다. 둘째, 단순화한 영어 글을 읽은 집단 학생들의 경우 추론을 요구하는 문제보다는 글에서 명시된 정보를 확인하거나 종합하는 문제에서 다른 집단보다 좋은 점수를 얻었다. 셋째, 단순화한 글을 읽은 집단이 상세화한 글이나 원문을 읽은 집단보다 글을 더 쉽다고 인식하였으며, 자신들이 비교적 글의 내용을 잘 이해하고 있다고 생각한 것으로 나타났다. 이와 같은 결과를 종합하여 볼 때, 성인 학습자들에게 상세화한 외국어 입력이 더 효과적이라는 기존 연구의 결론을 지지할 수 없었다. 이와는 반대로 본 실험의 대상이 된 하위 단계 학습자들에게는 단순화한 외국어 입력이 보다 효과적인 것으로 나타났다. 이는 상세화한 영어 교재의 경우 원문보다 길이가 길어지고 추가적인 어휘가 늘어나게 되기 때문에 어휘력과 독해 능력이 낮은 하위 단계 학습자들에게 부담을 주었기 때문이라고 추정할 수 있다. 따라서 성인 학습자들의 경우에도 외국어 능력 단계에 따라 알맞은 수정 언어 입력의 형태를 고려하여 가르쳐야 한다고 본다. This study explored what type of English text modification would be most effective for reading comprehension by lower level university learners. 139 university students were divided into three groups and participated in a brief experiment. Each group was tested reading comprehension ability after reading unmodified text, simplified text and elaborated text respectively. The three groups also answered to a comprehensibility judgment questionnaire. The results showed that the students who read the simplified text obtained the best scores in the comprehension ability test. The students who read the elaborated text showed the worst comprehension of the text. In addition, the students who read the simplified text perceived the text easiest whereas the students who read the unmodified version preceived the text hardest in the comprehensibility questionnaire. These results imply that the elaborated input does not always help to promote university students' reading comprehension particularly in the case of lower level learners.

The Effect of Transportation Policy Changes on Retail Market Trade Area Dynamics

Shin,Seung Woo,Kim,Gyoung Sun 한국주거환경학회 2018 주거환경(한국주거환경학회논문집) Vol.16 No.3

Ⅰ. Introduction Ⅱ. Literature review III. Data IV. Discussion V. Conclusion 본 연구의 목적은 서로 다른 두 개의 교통정책이 서울의 한 상권에 미치는 동태적 영향을 다룬다. 버스 노선의 변화나 새로운 지하철의 개통이 주변 상권의 형성이나 시간적 변화에 미치는 영향을 검증한다. 이러한 가설을 검증하기 위한 방법을 구체적으로 설명하면, 상권내 토지의 과세가치를 이용하여 경사도를 측정한다. 본 연구를 통하여, 이미 교통 기반시설이 충분히 보급된 지역의 경우, 버스노선의 변경은 상권에 제한적인 영향만을 미치는 것을 확인하였다. 반면 이미 두 개의 지하철 노선이 운영 중인 동일한 지역에 추가된 세 번째 노선은 통계적으로 유의한 영향을 미치는 것을 t-테스트를 통하여 확인하였다. 또한 상권의 시간적 변화를 가시화하였다. 본 연구가 제안한, 과세 평가액과 이를 사용하여 계산된 경사도를 활용한 혁신적인 연구방법은 도시지역의 사회실험을 대체할 수 있는 효과적인 대안이다.

Theoretical Study of Divided Nations and Peace Tourism

Shin,Young-Sun 한국문화관광학회 2004 문화관광연구 Vol.6 No.1

This paper attempts to define how to categorize tourism between divided nations, that is, separate political units that one were parts of a larger unit, subdivided by internal or external forces. Even though this research approach to the problem stems from a concern about the problem of classification of tourism between divided nations (whether such travel is international or domestic), research’s examination opens up interesting perspectives on such factors as power relations in tourism and the meaning of boundaries, both national and mental. Sometimes domestic tourism may include a crossing of boundaries much more significant than international borders. Since tourism development in any given country is affected by the political environment, understanding the implications of various political conditions with a relationship to tourism, is important since it will assist to determine the likely outcomes on tourism activity.

반코마이신 내성 장내구균 분리 환자에서 황색포도알균의 내성

김동욱,신선혜,김혜진,류선,이선희,장철훈,김영대,곽임수 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

목적 : Vancomycin-resistant enterococci (VRE)로부터 S. aureus로의 vacomycin 내성 유전자의 전파는 오래전부터 예견되어져 왔으며 큰 걱정거리로 남아있다. 최근에 vanA 유전자를 가지고 있는 vancomycin-resistant S. aureus 2주가 미국에서 분리되었다. 이 연구의 목적은 VRE를 보균하고 있는 환자들에서 S. aureus 보균양상과 항균제 내성을 알아보는데 그 목적이 있다. 재료 및 방법 : 2001년 1월부터 2001년 12월까지 부산대학교병원에 입원하였던 환자들 중 임상검체에서 VRE가 분리된 환자 7명과 2001년 9월부터 12월까지 외과 중 환자실에 입원하였던 환자들 중 VRE 감시배양을 시행하였던 20명의 환자들을 대상으로 하였다. 환자들은 전비공, 액와부, 회음부, 직장에서 매주 면봉으로 검체를 채취하였다. 선별배지에서 검체를 배양하여 S. aureus를 분리하였고 원판 확산법을 이용하여 methicillin 감수성을 측정하였다. Broth microdilution 법으로 vancomycin MIC를 측정하였다. 결과 : 총 27명에서 73회의 방문과 292회의 배양이 시행되었으며 총 67주의 S. aureus가 분리되었다. 이중 64주(95.5%)가 methicillin 내성이었다. 전비공 MRSA 보균율은 VRE를 보균하고 있었던 환자는 19명 중 11명(58%)에서, VRE를 보균하지 않았던 환자는 8명 중 3명(37.5%)으로 VRE 보균자에서 보균율이 더 높았다. 총 64주의 MRSA의 vancomycin MIC의 분포는 0.5-2㎍/mL였으며 2㎍/mL를 초과하는 균주는 발견되지 않았다. 64주 중 vancomycin MIC가 1㎍/mL인 균주가 54주(84.4%)로 가장 많았으며 2㎍/mL 6주(9.4%), 0.5㎍/mL 4주(6.3%)의 순이었다. 결론 : VRE 환자에서 S. aureus의 보균율은 비보균자 보다 높았으며 분리된 균주들은 대부분 MRSA였다. VRSA 균주는 발견되지 않았다. Background : The transfer of vancomycin resistance from vancomycin-resistant enterococci (VRE) to Staphylococcus aureus has been predicted. The purpose of this study is to determine the prevalence and antibiotics resistance of S. aureus among patients colonized with VRE. Methods : Between January 2001 and December 2001, a prospective study was performed at Pusan National University Hospital on 27 patients. Surveillance swabs from nasal cavity, axilla, perineum, and rectum were obtained at weekly intervals. Methicillin susceptability of S. aureus was determined by oxacillin disk diffusion test and minimum inhibitory concentration (MIC) for vancomycin by microdilution broth test. Results : Total of 292 swab cultures were performed and 67 S. aureus isolates were collected. 64 isolates (95.5%) were resistant to methicillin. The prevalence of nasal MRSA carrier in 19 patients colonized with VRE was higher than that in 8 patients not colonized with VRE (58% vs. 37.5%). In 64 MRSA isolates, MIC (㎍/mL) for vancomycin ranged from 0.5 to 2. No isolates with MIC >2 ㎍/mL were observed. MIC of 1 ㎍/mL was shown (observed) in 54 isolates, 2 ㎍/mL in 6 isolates, and 0.5 ㎍/mL in 4 isolates. Conclusion : The prevalence of S. aureus with colonization of VRE is higher than that without colonization of VRE. Most of S. aureus isolates were resistant to methicillin. VRSA isolates were not observed.

[P509] Lichen planus pigmentosus presenting with flexural area

( Young Bin Shin ),( Jeong Won Jo ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Lichen planus pigmentosus (LPP) is an uncommon variant of lichen planus that tends to occur in middle-aged individuals with darker pigmented skin. Clinical findings include hyperpigmented, brown to gray-brown macules and patches on sun-exposed areas and, in the rare inversus variant, on the flexural areas and intertriginous zones. The pattern of pigmentation is generally diffuse, although follicular, reticular, and unilateral linear variants have been described. We recently encountered a rare case of LPP developed in flexural area, not in sun-exposed area. A 58-year-old male patient presented with brown macules on the inguinal area for 6 months. One or two dark brown macules first appeared and spread gradually. A physical examination showed multiple, ill-defined, dark brown macules on inguinal area. The dermoscopic finding showed mottled pattern and elevated margin. The incisional biopsy was performed and a diagnosis of LPP was made. The fact that LPP can develop in non-sun-exposed areas as well as sun-exposed ones requires a new hypothesis for the pathogenesis of LPP.