Comparison of Melanoma Subtypes among Korean Patients by Morphologic Features and Ultraviolet Exposure

( Hong Sun Jang ),( Jee Hung Kim ),( Kyu Hyun Park ),( Jae Seok Lee ),( Jung Min Bae ),( Byung Ho Oh ),( Sun Young Rha ),( Mi Ryung Roh ),( Kee Yang Chung ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.4

Background: Genetic alterations have been identified in melanomas according to different levels of sun exposure. Whereas the conventional morphology-based classification provides a clue for tumor growth and prognosis, the new classification by genetic alterations offers a basis for targeted therapy. Objective: The purpose of this study is to demonstrate the biological behavior of melanoma subtypes and compare the two classifications in the Korean population. Methods: A retrospective chart review was performed on patients found to have malignant melanoma in Severance Hospital from 2005 to 2012. Age, sex, location of the tumor, histologic subtype, tumor depth, ulceration, lymph node invasion, visceral organ metastasis, and overall survival were evaluated. Results: Of the 206 cases, the most common type was acral melanoma (n=94, 45.6%), followed by nonchronic sun damage-induced melanoma (n=43, 20.9%), and mucosal melanoma (n=40, 19.4%). Twenty-one patients (10.2%) had the chronic sun-damaged type, whereas eight patients (3.9%) had tumors of unknown primary origin. Lentigo maligna melanoma was newly classified as the chronic sun-damaged type, and acral lentiginous melanoma as the acral type. More than half of the superficial spreading melanomas were newly grouped as nonchronic sun-damaged melanomas, whereas nodular melanoma was rather evenly distributed. Conclusion: The distribution of melanomas was largely similar in both the morphology-based and sun exposure-based classifications, and in both classifications, mucosal melanoma had the worst 5-year survival owing to its tumor thickness and advanced stage at the time of diagnosis. (Ann Dermatol 26(4) 485~490, 2014)

Ganglioside GM1 influences the proliferation rate of mouse induced pluripotent stem cells

( Jae-sung Ryu ),( Kyu-tae Chang ),( Ju-taek Lee ),( Malg-um Lim ),( Hyun-ki Min ),( Yoon-ju Na ),( Su-bin Lee ),( Gislain Moussavou ),( Sun-uk Kim ),( Ji-su Kim ),( Kinarm Ko ),( Kisung Ko ),( Kyung- 생화학분자생물학회(구 한국생화학분자생물학회) 2017 BMB Reports Vol.50 No.6

The ACKNOWLEDGEMENTS should be corrected as follows, "This research was supported by a grant (Code# PJ0074922012) from the Korean Rural Development Administration, and has been supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education Science and Technology (2010-0022316 and KCG5401011), and the KRIBB/KRCF Research Initiative Program (NAP), Korea. The published article in this journal was a part of the 2013 Doctoral thesis of Jae-Sung Ryu submitted to Wonkwang University, Korea." and not "This research was supported by a grant (Code# PJ0074922012) from the Korean Rural Development Administration, and has been supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education Science and Technology (2010-0022316 and KCG5401011), and the KRIBB/KRCF Research Initiative Program (NAP), Korea."

Flexural Responses of Prestressed Hybrid Wide Flange Composite Girders

Sun?Jin Han,Deuck Hang Lee,Jae?Yuel Oh,Seung?Ho Choi,Kang Su Kim 한국콘크리트학회 2018 International Journal of Concrete Structures and M Vol.12 No.5

In this study, prestressed hybrid wide flange (PHWF) composite girders were proposed, and full-scale flexural tests were conducted to evaluate their structural performances. This new proposed girder system was developed and designed to effectively resist external loads considering the actual construction sequences. Two specimens with and without shear connectors were fabricated and tested to examine the effect of the shear connectors for achieving the fully-composite behaviors between a cast-in-place (CIP) concrete and the prefabricated prestressed steel–concrete composite girder. The test results showed that sufficient flexural strengths and deformation capacities can be obtained in both types of PHWF composite girders with and without shear connectors. To reflect the actual construction stages of the proposed PHWF composite girder, nonlinear flexural analyses were proposed considering the prestress effect and segmental effect before and after composite with the CIP concrete, respectively. The observed and analysis results of strain behaviors of the PHWF girder specimens were also compared and discussed in detail.

녹비작물재배에 따른 고려인삼의 생육특성

Bong Jae Seong,Sun Ick Kim,Ka Soon Lee,Moo Geun Jee,Hyun Ho Kim,Jun Yeon Won 한국약용작물학회 2016 한국약용작물학술대회 발표집 Vol.2016 No.05

Background : The authors of this study analyzed the effect of the green manures cultivated in the soil of the preparation field in order to select the green manures suitable for ginseng cultivation and the effect of the green manures on the variation of ginseng growth development, the content of crude saponin and yield ability with the aim to use the results as the primary data for improving the quality of ginseng. Methods and Results: To analyze the effect of the application of green manures on the growth of ginseng, the authors cultivated 4 varieties of green manures and installed blue polyethylene sheet and one-layered black polyethylene net+three-layered blue polyethylene net(OBPNTB) and sun-shading material on the managed soil by re-applying green manures and then cultivated ginseng. The results suggested that the growth of ginseng was excellent in the barley+hairy, barely and rye cultivation plot in the plot treated with OBPNTB rather than the cultivation plot teated with Blue polyethylene sheet(BPS) and two-layered blue & two-layered black polyethylene net(TBTBPN), and the growth of leaf length and stalk diameter was excellent in barely + hairy vetch material. For the underground root weight, the growth was the most excellent(30.19g) in the barley+ hairy vetch cultivation plot treated with OBPNTB. For the underground red discoloration and root rot, the incidence rate was the lowest in the plot treated with BPS in which the water leak in a levee was small than in the test plot treated with sun-shading net. For the ginsenoside content in the cultivation plot treated with TBTBPN, the ginsenoid content was the highest in the rey cultivation plot, and it was the highest in the cultivation plot treated with OBPNTB. Conclusion : The results of study suggested rye among green manures is the most suitable for the growth of ginseng; underground growth was the most prominent in the plot treated with sun-shading net material (black 1 + blue 3) and the underground ginsenoside content was the most prominent in the rye cultivation plot and the plot treated with the sun-shading sheet.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

朝鮮時代 女性의 頭飾에 관한 연구

이선재,고미연 숙명여자대학교 건강ㆍ생활과학연구소 1997 生活科學硏究誌 Vol.12 No.1

The purpose of this study was to arrange Cho Sun Dynasty woven hair styles and hair decoration and hat. Due to this government regulation, the hair style of woven, EUNJUN MEURI(얹은 머리) was replaced by JOK MEURI(쪽머리). The hair styles of women during the period of middle and latter part of Cho Sun Dynasty were variously beautified and they may be classfied into QUEN MEURI(큰머리), EUNJUN MEURI(얹은머리), JOK MEURI(쪽머리), JOJIN MEURI(조진머리), SAYANGGAE(생머리), GHOPJI MEURI(첩지머리) and TTAEUN MEURI(땋아늘인 머리) etc. EUNJUN MEURI(얹은머리) withbig wig was popular until the proclamationof prohibition by king Jeong-Jo in Cho Sun Dynasty. And DDELGAM(떨잠) used in EUNJUN MEURI(얹은머리). Veil essentially created as a result of the social rule imposed on women in during of the Cho Sun Dynasty. Veil was used in many different ways as an official cap. There were many kind of veil such as NEOUL(너울), MYUNSA(면사), CHANGUI(장의), SSEUGAECHIMA(쓰개치마), JEONMO(전모), CHEONUI(천의), CHAAEK(차액) in this Dynasty. Warm hat is thought to have been originated at the first to adapt to the climate. We can pressent YIAM(이엄) as the typical model, and warming hats which were differentiated from YIAM(이엄) appeared with various ornamental characteristics. The representative warming hats of this age were NAMBAWI(남바위), PUNGCHAE(풍차), CHOBAWI(조바위), AYAM(아얌), KULLE(굴레), etc. The materials used were various. Most of the textile was silk with the lining of cotton or cotton flannel.

일광담마진 (日光蕁麻疹)

이재준(Jae Joon Lee),황선욱(Sun Wook Hwang),김영표(Young Pio Kim) 대한피부과학회 1985 대한피부과학회지 Vol.23 No.1

We herein described a 27 year-old male who has been suffering from pruritic erythematous wheal and flare on sun-exposed areas, especially the midback for the past, ten months. The action spectrum of this patient was between 320 and 400 nm, .Passive and reverse passive transfer tests were negative. According to the classification by Harber et al, the current case seemed to belong to type II.

Development of Sun-Glint Prediction Program For The Communication, Ocean and Meteorological Satellite

Park Jae-Ik,Choi Kyu-Hong,Park Sang-Young,Lee Byoung-Sun,Ahn Yu-Hwan 한국우주과학회 2004 한국우주과학회보 Vol.13 No.2

한국해안으로부터 Purple, Non-Sulfur Photosynthetic Bacterium, Rhodobacter sp. EGH-24의 분리 및 특성

차미선,김기한,조순자,이나은,이정은,이재동,이상준,박재림 한국환경과학회 2003 한국환경과학회지 Vol.12 No.12

A species of facultative photo-organotrophic, purple, non-sulfur bacterium was isolated from the 47 point at west and south coast of Korea in September 2001. Separated 13 samples of changes with red color under 28~32 ℃, 3000 lux, anaerobe conditions for 7 days cultivated in basal medium. For pure isolation from 13 samples, we used agar-shake tube method (0.4 % agar) and separated 5 strains through 13-repetition test. EGH-24 and EGH-30 was identified as the same strain through the RAPD(Random Amplified Polymorphic DNA)-PCR of strain EGH-9, EGH-13, EGH-23, EGH-24, EGH-30. Four isolates cultivated in synthesis wastewater for wastewater biodegradation test. EGH-24 was selected with efficient wastwater treating strain. Based on the results obtained from morphology, nutrient requirements, major bacteriochlorophyll content, 16S-rDNA phylogenetic analysis, EGH-24 strain may be identified as a new strain of the genus Rhodobacter and named Rhodobacter sp. EGH-24.

언론법제 연구의 최근 동향분석

이승선(Seung Sun Lee),이재진(Jae-Jin Lee) 한국언론법학회 2011 언론과 법 Vol.10 No.1

이 연구는 2007년부터 2010년까지 4년 동안 법학 및 언론학 분야의 학술지에 게재된 언론법관련 논문과 2009-2010년 출판된 언론법 관련 단행본, 또 같은 기간동안 발표된 언론법 관련 석?박사학위 논문을 내용분석하였다. 29개의 학술지에 게재된 언론법관련 논문의 비중은 전체적으로 9.2%였다. 한국언론법학회의 <언론과 법>, 한국정보법학회의 <정보법학>은 특성상 대부분 언론법관련 논문을 게재하였고 지상파방송 3사가 발행하는 학술지들도 ‘미디어정책’을 비롯한 언론법과 관련된 주제의 연구논문 게재비율이 상대적으로 높았다. 광고학분야 저널의 언론법 관련 연구논문 게재비율은 극히 낮았다. 법학 배경을 가진 연구자들이 언론학분야의 학술지에 연구논문을 게재하는 등 꾸준한 학문간 통섭이 이뤄지고 있으나 아직 기대수준에 미치지 못한 것으로 분석되었다. 언론법 관련 연구주제는 ‘저작권 등 지적재산권’ 부분이 상대적으로 큰 비중을 차지하였고 대부분의 연구가 전통적인 ‘규범적’ 연구방식에 의해 진행되는 경향이 강했다. 학위논문의 경우 예술계와 이공계에서도 언론법으로 분류되는 박사학위논문이 생산됐으나 여전히 법학분야가 ‘언론법박사학위논문’의 산실을 담당하고 있는 것으로 나타났다. 석사학위논문에서도 유사한 경향이 나타났는데 연구주제는 ‘저작권 등 지적재산권’ 비중이 컸다. 또 상당수가 온라인 부문과 직간접적인 연관을 맺고 있었다. 법학과 언론학 간의 꾸준한 교류와 공동연구, 또 법학전문대학원의 언론법 연구 활성화가 필요한 시점이다. This study explored the state of media law research through overviewing the related books, research articles, and academic theses produced during the years of 2009 and 2010. It showed that about 9.2% of all the research articles in media and law journals were written about media law. While the articles in <Media and the Law> and <Journal of Information Law> are mostly related to media law, journals about advertising published the least articles about media law. It was found that media researchers frequently applied social scientific methods for the main anaylsis, most law researchers highly depended on the conventional legal research methods. Major research interests in both media and law areas were given to freedom of expression and basic personality rights such as libel, invasion of privacy, and copyrights. Overall, there has still been not much co-work or co-authorship between media scholars and law scholars notwithstanding the recent increase in the number of media law related articles. In academics, among 27 Ph.D. degrees endowed in media law speciality, 21 came from law area, two from media area, four from other area. Interestingly, in master"s degree, more people eared master"s degree in other area than media area. This showed the interest in media law is getting increased in recent years. The books published during 2009 and 2010 proved that "copyright" is the most attractive and complicated issue among others in the media law research area. An interesting thing is that two books that deal with ethics in the internet were published in this period. Conclusively, this study suggested just like the result derived from 2008 article by Jae-Jin Lee and Seoung Sun Lee, more and more cooperative research between the media and the law should be made so as to enhance the development of media law research. Especially, the result revealed that unique and representative research method in the media law area needed to be established.