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Big Data in Healthcare Hype and Hope
Sul Gi, Kim(김슬기) (사)한국CDE학회 2013 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2013 No.1
The potential of Big Data allows us to hope to slow the ever-increasing costs of care, help providers practice more effective medicine, empower patients and caregivers, support fitness and preventive self-care, and to dream about more personalized medicine. Yet, as with the Internet, social media, and cloud computing, early enthusiasts are creating hyperbolic expectations about how and how quickly Big Data will transform healthcare. A number of issues challenge the adoption and success of healthcare Big Data, including privacy and security, who owns the data, and the regulatory labyrinth. Furthermore, real advances depend on better ways to exploit the disconnected puddles and lakes of existing data as well as better ways to generate, capture, analyze and make use of the streams of new kinds of data that are about to flood healthcare. This paper will introduce to Big Data and explore how it is becoming a growing force in the changing healthcare landscape.
Detection by PCR of Psyllid, Diaphorina citri Kuwayama, Vector of Citrus Huanglongbing Disease
Sul kyoung Park,Gi Don Kim 한국응용곤충학회 2014 한국응용곤충학회 학술대회논문집 Vol.2014 No.10
The Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Psyllidae), is the most important citrus pest, because it serves as a vector of “Candidatus Liberibacter” species that cause huanglongbing disease. Thus, when exporting Rutaceae (citrus), exporting countries put them into quarantine. However, as the size of an imago is so small that only skilled experts can identify it using morphology-based species identification. A PCR-based assay was developed for monitoring psyllids using a rapid, using the DNA extraction from psyllid bodies and PCR amplification. Thus, this study aims to develop a DNA marker system with high species specificity and discrimination power that helps identifying psyllid. We analyzed the base sequence of mitocondria DNA. Based on this sequence, restriction sites were determined and a species particularity primer was made. Several polymorphic regions of mitochondrial DNA of both species were sequenced and used for developing specific restriction sites and polymerase chain reaction (PCR) primers. Also, species-specific PCR primers were devised to develop diagnostic PCR method for identifying the internal feeders. Base sequence results from PCR, which used psyllid species-specific primers, was analyzed by the Mealign program of the CLC Main Workbench analysis software, and used to develop a phylogenic tree. After analyzing this, Hemiptera proved to be allied species.
Microstructure and Nanosize Precipitate of Nitrided 316L Stainless Steel
Sul Gi Kim,Jae Nam Kim,Jei Pil Wang,Chang Yong Kang 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.1
The microstructure and nanosize precipitates of nitrided 316L stainless steel were investigated mainly by transmissionelectron microscopy (TEM) and X-ray diffraction analysis. Nitriding treatment performed in a molten salt bath followedby cooling down to ambient temperature and further diffusion treated. Produced layer consist of surface layer at the top,compound layer in the middle and final diffusion layer. Supersaturated phase is γ′N not γ-Fe4N. The lattice parameter ofγ′N is expanded about 16% by nitrogen supersaturation. Precipitates size of few nm were observed in the compound layers. These nanosize precipitates were coarsening up to ~ 40 nm by further heat treatment at 450 °C for 1 h. It was identified asSi3N4by energy dispersive X-ray spectrometer, selected area electron diffraction patterns at two different zone axes [110],[114] and high resolution TEM analysis.
Identification of Mycorrhizal Symbiont Detected in Roots of Two Cymbidium Species Native to Korea
Sul Gi Lee,Jong Suk Lee,Sun Hee Choi 한국화훼학회 2019 화훼연구 Vol.27 No.1
In Korea, the orchid species Cymbidium goeringii and C. kanran are very important as natural genetic resources and floriculture crops. With respect to nutrient uptake, both species mixotrophic, and can shift to autotrophy with the development of photosynthetic organs. In this study, microscope observation was performed to examine the existing symbiotic fungi and their pelotons in root cortical tissues. Molecular identification was performed to identify orchid mycorrhizal fungi (OMF) and evaluate phylogenetic relationships with other OMF taxa in the database. Essential molecular data encompassing ribosomal internal transcribed spacers (ITS) were amplified from the extracted genomic DNA of root tissues. The hyphae grown into cortical root tissues of two individual cymbidiums were observed and revealed to form typical coiled structures called pelotons. OMF sequences obtained from C. goeringii root tissues were determined to be 673 bp nucleotide sequences (MF101371), while those obtained from C. kanran root tissues were 788 bp nucleotide sequences (MF101372). The resulting ITS rDNA sequence was analyzed using the UPGMA cluster analysis method and a dendrogram was generated. According to the phylogenetic tree, the ITS rDNA sequence from C. goeringii was positioned among other Tulasnella species, and that from C. kanran was grouped with Russula species. Producing elementary, but fundamental, data about the nutritionally helpful symbiotic mycorrhizal fungi is very important to facilitate orchid-fungal microbe interactions and for cultivation and conservation programs for native orchids.
Park, Sul-Gi,Kim, Sang-Hun,Kim, Kwang-Youn,Yu, Sun-Nyoung,Choi, Hyeun-Deok,Kim, Young-Wook,Nam, Hyo-Won,Seo, Young-Kyo,Ahn, Soon-Cheol Springer-Verlag 2017 PHARMACOLOGICAL REPORTS Vol.69 No.1
<P>Conclusion: ROS-mediated activation of p38/ERK partially contributes to Toyocamycin-induced apoptosis, and p38/ERK MAPKs regulate the ROS production in PC-3 cells. (C) 2016 Institute of Pharmacology, Polish Academy of Sciences. Published by Elsevier Sp. z o.o. All rights reserved.</P>