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이건수,안인철 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.2
Purpose : To assess the changes of treatment of phenobarbital, carbamazepine, valproic acid and polytherapy on serum lipids in epileptic children. Method : We determined serum levels of total cholesterol(TC), high-density lipoprotein cholesterol(HDL-C), low-density lipoprotein cholesterol(LDL-C), and triglycerides in 50 healthy children and in 80 children with epilepsy who had been receiving phenobarbital(9 patients), carbamazepine(20 patients), valproic acid(30 patients), or polytherapy (21 patients) Results : In the group receiving phenobarbital, mean TC, HDL-C and LDL-C levels were significantly higher than in the control group. In the group receiving carbamazepine, mean TC levels were significantly higher than in the control group. In the group receiving valproic acid, mean triglyceride and HDL-C levels were significantly lower than in the control group, but mean LDL-C/HDL-C ratio were significantly higher than in the control group. In the group receiving polytherapy, mean TC and LDL-C levels were significantly higher than in the control group. In neither group did mean TG/HDL-C ratio differs significantly from the corresponding control groups. Conclusion : Our results suggest long-term treatment of anticonvulsants significantly modify serum lipids in epileptic children.
이건수,안인철 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1
25 cases under 15 years of age with neuronal migration disorders were observed at the department of Pediatrics at Chungnam National University Hospital during a period of 6 years from January, 1992 to December, 1997. The results were as follows: 1. The peak incidence of age was 5 to 10 years(40.3%). The sex ratio of male to female was 1.8 : 1. 2. The types of neuronal migration disorders were cortical dysplasia (36%), lissencephaly(28%), schizencephaly(16%), heterotopia(12%) and megalencephaly(8%) in order of frequency. 3. The clinical findings were seizure(76%), delayed development(48%), delayed speech(32%), mental retardation(24%) and motor deficit(20%) in order of frequency. 4. The locations of disorder were frontal lobe(72%), parietal lobe(60%), temporal lobe(40%) and occipital Iobe(32%) in order of frequency. 5. The abnormal EEG findings were 17 cases(68%). Among these cases, focal abnormalities were 5 cases(29.4%), general abnormalities were 11 cases(64.7%) and abnormal background was 1 case(5.9%). 6. The seizure types were generalized seizure(63.2%), partial seizure (31.6%) and mixed seizure (5.3%) in order of frequency. 7. The patients with larger size of lesions had more delayed development, delayed speech and mental retardation.
이건수,안인철 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1
16 cases with floppy infant syndrome were observed at the department of Pediatrics at Chungnam National University Hospital during a period of ll years from January, 1986 to December, 1996. The results were as follows: 1. The incidences of disease were Werdnig-Hoffman disease(W-H-D, 7 cases), Guillain-Barre syndrome(GBS, 3 cases), congenital muscular dystrophy(2 case), congenital myasthenia gravis (2 cases), congenital myotonic dystrophy(1 case) and neonatal myasthenia gravis(1 case) in order of frequency. 2. The sex ratio of male to female was 1.3 : 1. 3. The main symptoms and signs were decreased muscle tone(93.8%), decreased tendon reflex (75%), dysphagia(75%), respiratory distress(75%), abnormal traction response(68.8%), abnormal vertical response(68.8%), weak crying(62.5%), poor head control(62.5%), frog leg posture(62.5%) and fasciculation(31.3%) in order of frequency. 4. The EMG findings of W-H-D and GBS were increased amplitude and duration. The EMG findings of congenital muscular dystrophy and congenital myasthenia gravis were reduced amplitude and duration. The EMG findings of congenital myotonic dystrophy and neonatal myasthenia gravis were normal. 5. The ceatine kinase(CK) levels of W-H-D, GBS, congenital myasthenia gravis and neonatal myasthenia gravis were normal. The CK levels of congenital muscular dystrphy and congenital myotonic dystropohy were increased.
Costanzo Pablo René,Suárez Sebastián Matías,Kozak Andrea Elina,Knoblovits Pablo 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.2
Purpose:Purpose: Vitamin D (VD) acts on sperm motility, capacitation and survival but its role in steroidogenesis is less clear. Aims: To analyze seasonal variations in sex steroids and VD in a healthy male population. Materials and Methods:Materials and Methods: Twenty-nine healthy males, 34.0±4.8 years were included. Blood collection in winter (W) and sum-mer (S) was performed to measure: 25OHD, total testosterone (TT), free testosterone (FT), estradiol (E2), luteinizing hormone (LH), and sex hormone binding globulin (SHBG). Testosterone/estradiol (T/E2) ratio was calculated. Results:Results: In W, lower levels of 25OHD: 18.8±7.2 ng/mL vs. 38.8±11.9 ng/mL (p<0.0001) and LH: 3.5±1.2 mU/mL vs. 3.9±1.5 mU/mL (p=0.05), and higher levels of TT: 501.9±157.7 ng/dL vs. 405.0±128.0 ng/dL (p=0.0003), FT: 11.8±4.1 ng/dL vs. 10.2±3.7 ng/dL (p=0.017), SHBG: 28.5±10.9 nmol/L vs. 23.6±7.9 nmol/L (p=0.002) and T/E2 ratio: 30.7±19.7 ng/dL/pg/mL vs. 17.3±3.6 ng/dL/pg/mL (p=0.0015) with no variation in E2 levels were observed. A positive correlation between 25OHD and E2 (r=0.28, p=0.04) and negative correlations between 25OHD and TT (r=-0.27, p=0.049), 25OHD and FT (r=-0.32, p=0.01), and 25OHD and T/E2 (r=-0.44, p=0.0008) were found. Conclusions:Conclusions: In healthy young male population, seasonal variations were observed in 25OHD and LH levels (higher in S) and in TT, FT, SHBG levels, and T/E2 (higher in W). Lower values of TT and FT in S are accompanied by higher levels of LH, which rules out a central mechanism for lowering testosterone. 25OHD negatively correlated with TT, FT, and T/E2 and posi-tively correlated with E2, suggesting a relationship between VD status and changes in gonadal steroids.
황치관,이건수,안인철 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1
Routine liver function test is done in epileptic children receiving antiepileptic drugs to prevent hepatotoxicity induced by these drugs. The abnormalities of liver function test are rarely seen, but these abnormalities accompanied by the clinical manifestation of hepatotoxicity are seldomly seen. This study carried out in order to assess the efficacy of routine liver function test in epileptic children. We examed the changes of the serum level of aspartate transferase(AST), alanine aminotransferase(ALT), total bilirubin, total protein, albumine, alkaline phosphatase(ALP) before and after antiepileptic drug medication in 60 epileptic children who had been receiving valproic acid(n=25명), ethosuximide(n=6명), carbamazepine(n=4명), valproic acid and carbamazepine(n= 14명), and other polytherapy(n=11명) for 3months or more. Results are as follows ; 1) The difference in each groups according to age, duration of treatment, and drug plasma concentration was not found. 2) AST was within normal range in any group, but decreased after valproic acid, ethosuximide, carbamazepine, and other polytherapy treatment. 3) ALT was within normal range in any group, but decreased after valproic acid treatment. 4) Total bilirubin, total protein, albumin, and ALP were within normal range in any groups. 5) Y-GT was within normal range, but the values were increasing tendency in polytherapy groups. 6) No clinical significant menifestations had developed during study period in any groups. The result suggest that the routine liver function test itself can not be the indicator of hepatotoxicity, and that the liver function test exammed when the clinical symptoms appear is more effective than the routine liver function test.
Min Su,Hongjiu Su,Baolei Du,Xiaotong Li,Gaoyuan Ren,Shudong Wang 한국화학공학회 2015 Korean Journal of Chemical Engineering Vol.32 No.5
Silica nanoparticles with different sizes (ranging from 10 nm to 104 nm) and size distributions were synthesized by semi-batch and semi-batch/batch methods of the Stöber process. Then the amorphous silica with different surface areas (ranging from 30m2/g to 400m2/g) and pores (ranging from 3 nm to 33 nm) were obtained by various aging treatments and drying methods of the synthesized colloidal silica sol. The aging treatment resulted in the monodispersed pore distribution and decreased BET surface area of silica. The high-humidity drying method led to the mesoporous silica with uniform pores and decreased small pores. As the silica was obtained by the arrangement of silica nanoparticles, the pore diameter and pore distribution of mesoporous silica were directly related to the size and distribution of nanoparticles. Furthermore, this study offered a new thought for the synthesis of other mesoporous materials with uniform pore distributions.
일반논문 : 몽골 대학의 한국어 교재에 나타난 유의어 분석
에르덴수랭 ( Z Erdene Su Ren ) 한양대학교 동아시아문화연구소(구 한양대학교 한국학연구소) 2013 동아시아 문화연구 Vol.54 No.-
외국어를 학습할 때 기본 문법이나 어휘를 배우는 것이 중요하지만 학습자들이 초급 단계에서 중, 고급 단계로 올라갈수록 상황에 적합한 어휘를 사용하고 보다 정확하게 그 의미의 차이를 이해하는 것이 중요하다. 그리하여야 자신이 전달하고자 하는 의미를 정확하게 표현하고 상대방의 의도를 이해할 수 있는 전문적인 인재로 발전할 수 있기 때문이다. 특히 몽골인 학습자들의 특징은 비한자문화권 한국어 학습자고 또한, 영어보다 러시어가 가까운 이유로 학습 단계가 올라갈수록 어휘 교육에 어려움을 겪고 있다. 그래서 어휘 중 유의어 학습을 개선 할 수있는 방법으로 학습자 및 교사를 위한 유의어 쌍 목록집을 제시하는 것이 효과적이라고 판단하였다. 이번 연구는 몽골인 한국어 학습자와 교사를 위한 교육용 기본 유의어 쌍 목록집을 제시하기 위하여 한국어 연구의 주 자료들을 통하여 한국어 교육용 기본 유의어 쌍 추출 목록을 선정하고 몽골에서 대표적인 몽골국립대학교 및 몽골인문대학교의 한국어 학과에서 사용하는 한국어 교재에 나타난 유의어를 분석하였다. 그래서 몽골인 학습자를 위한 교육용 한국어 기본 유의어 쌍 목록 선정 및 몽골대학교 한국어 학과에서 사용하는 교재의 색인 부분에 없지만 한국어교육용 기본 유의어 추출 목록에는 존재하는 유의어 쌍 중 선별하여 몽골인 학습자를 위한 한국어 교육용 기본 유의어 쌍 보완 추출 목록을 선정하였다. 그 결과 명사유의어 460쌍(43.9%), 동사유의어 354쌍(33.6%), 형용사유의어 136쌍(12.9%), 부사유의어 101쌍(9.6%)으로 총 1051쌍을 추출하였다. 단계별로 보면 초급 단계 154쌍(14.6%), 중급 단계 353쌍(33.5%), 고급 단계 546쌍(51.9%)으로 구성하여 선정하였다. South Korea and several countries have active partnership in all sectors of globalization, and they have friendly relations with Mongolia since establishment of the diplomatic relationship. The number of Mongolian people they are interest in Korean studies, Korean institution, Korean companies, and Korean institutions has been increased. For the first time the learners have learned in the Korean - Mongolian and contrast, but now there was a lot of interest about Korean and Korean studies. Mongolian learners, though do not find difficulties at the beginning, understanding of the kanji-based Korean language is found to be an uphill task at the higher stages of the education. Although it is imperative to learn the basic grammar and vocabulary when studying a foreign language, understanding of the semantic differences of synonyms is equally important too. Because, having known such differences ensures fluent and precise use of vocabulary appropriate to the situation making easy and effective communication. Basic instructional Korean synonyms appeared in Korean textbooks used for the educational proposes at the Korean Department in Mongolian National University and Mongolian University of Humanities were extracted in this study. The results revealed that the vocabulary of both the learners and teachers could be improved effectively by the synonyms presented as a list of pairs of words with guidelines for the users.
TILINGS OF ORTHOGONAL POLYGONS WITH SIMILAR RECTANGLES OR TRIANGLES
SU, ZHANJUN,DING, REN 한국전산응용수학회 2005 Journal of applied mathematics & informatics Vol.17 No.1
In this paper we prove two results about tilings of orthogonal polygons. (1) P be an orthogonal polygon with rational vertex coordinates and let R(u) be a rectangle with side lengths u and 1. An orthogonal polygon P can be tiled with similar copies of R(u) if and only if u i algebraic and the real part of each of its conjugates is positive; (2) Laczkovich proved that if a triangle $\Delta$ tiles a rectangle then either $\Delta$ is a right triangle or the angles of $\Delta$ are rational multiples of $\pi$. We generalize the result of Laczkovich to orthogonal polygons.
TILINGS OF PARALLELOGRAMS WITH SIMILAR TRIANGLES
Su, Zhanjun,Ding, Ren 한국전산응용수학회 2007 Journal of applied mathematics & informatics Vol.23 No.1
We say that a triangle ${\Delta}$ tiles the polygon ${\rho}\;if\;{\rho}$ can be decomposed into finitely many non-overlapping triangles similar to ${\Delta}$. Let ${\rho}$ be a parallelogram with angles ${\delta}\;and\;{\pi}-{\delta}\;(0<{\delta}{\leq}{\pi}/2)$ and let ${\Delta}$ be a triangle with angles ${\alpha};{\beta},\;{\gamma}\;({\alpha}{\leq}{\beta}{\leq}{\gamma})$. We prove that if ${\Delta}$ tiles ${\rho}$ then either ${\delta}{\in}\;({\alpha},\;{\beta},\;{\gamma},\;{\pi}-{\gamma},\;{\pi}-2{\gamma})\;or\;dimL_{\rho}=dimL_{{\Delta}}$. We also prove that for every parallelogram P, and for every integer n $(where\;n{\geq}2,\;n{\neq}3)$ there is a triangle ${\Delta}$ so that n similar copies of ${\Delta}\;tile\;{\rho}$.