[A Story by An Su-gil] The Green Chrysanthemum

An Su-gil,Z?ng In-s?b(번역자) The Academy of Korean Studies 1969 Korea Journal Vol.9 No.7

알부민이 첨가된 시험관내 약역학 감염모델을 이용한 폐렴알균 치료에서 Ceftriaxone 일일 1회 요법

허지안,전혜선,박선희,최수미,김시현,이동건,최정현,유진홍,신완식 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

배경 : Penicillin 내성 폐렴알균이 증가하는 지역에서 대안 중의 하나로 사용되는 ceftriaxone (CTR)의 적절한 용법, 용량을 파악하는 것이 중요하다. 본 연구는 임상에서 분리된 폐렴알균을 대상으로 시험관내 약역학 감염모델을 이용하여 알부민이 첨가된 경우와 첨가되지 않은 경우 CTR의 일일 1회 요법의 효과를 비교해 보고자 하였다. 재료 및 방법 : Penicillin 감수성(SM24), 중간내성(SM47), 내성(SM60)주를 대상으로 2-구획 시험관내 약역학 감염모델을 적용하였다. CTR 주입은 2 g씩 24시간마다로 사람의 약동학을 모의하였다. 알부민은 모델에서 4g/ dL가 유지되도록 하였다. 살균효과는 0, 2, 4, 6, 24, 30, 48시간째 집락수 변화로 측정하였다. 결과 : 모든 균주에서 알부민이 첨가되지 않은 경우 6시간 이내에 살균력이 관찰되었다. 최저억제농도 및 알부민 첨가유무에 관계없이 3주 모두 24시간째 살균력이 관찰되었고, 48시간째는 모두 측정한계 이하의 집락수로 감소하였다. 전 실험과정에서 CTR에 대한 내성주는 출현하지 않았다. 결론 : CTR의 일일 1회 요법은 알부민이 첨가되었을 때, 감수성, 중간내성, 내성주 모두에서 살균력 발현이 지연되었으나 최종효과는 알부민이 없을 때와 다르지 않았다. 앞으로 알부민 결합효과와 관련된 기초적인 추가 연구가 필요할 것으로 생각된다. Background : During the era of increasing penicillin resistant Streptococcus pneumoniae, it is important to have knowledge about adequate dosage and dosing interval of ceftriaxone (CTR). We examined efficacies of once-daily CTR and compared results in an in vitro pharmacodynamic infection model (IVPDIM) supplemented with albumin and those without albumin. Methods : Using three clinically isolated S. pneumoniae that were susceptible (SM24), intermediate (SM47) and resistant (SM60) against CTR, we utilized a two-compartment IVPDIM. CTR 2 g was administered intravenously every 24 h. Human albumin was added with concentration of 4 g/dL. Samples were removed at multiple time points over a 48-h period to determine the colony counts. Results : In SM24 and SM60, bactericidal effects were observed within 6 hours in groups without albumin. The number of colonies during 1st 6 hours were more decreased in albumin-free groups than in albumin-supplemented groups (P<0.05). In SM47, similar results were found during 1st 6 hours (P=0.03). But, regrowth was observed in albumin supplemented group at 30 h. Irrespective of results of minimal inhibitory concentrations and albumin supplementation, bactericidal effects were shown at 24 h in all 3 strains. All groups were decreased below the detection limit at 48 h. Development of resistance was not detected throughout the entire study period in either strain. Conclusions : Although extents of killing in albumin supplemented broth of once-daily CTR dosing were delayed in all 3 strains compared with those of albumin free broth, final efficacies were not different between the two groups.

기능주의적 관점에서 본 학업성취에 대한 비판적 연구

안관수(An Kwan Su) 한독교육학회 2002 교육의 이론과 실천 Vol.7 No.2

Das Leistungsproblem erweist sich als grundlegendes Entscheidungsproblem der Erzieh- ungspraxis des institutionalisierten Bildungswesens und folglich als eine Kernfrage der Erziehungdtheorie. Der Leistungsbegriff in unserer Gesellschaft wird außerordentlich vielschichtig verwendet, so daß eine eindeutige Definition nicht möglich ist. Dennoch spielt die “Leistung” eine hervor- gehobene Rolle im Wertsystem in der Schule. Wir können also im wesentlichen drei Gruppen von Ansätzen einer pädagogischen Begriffsbestimmung der Leistung strukturieren: 1. eine konservative idealistische Pädagogik 2. eine fortschrittliche, technologische Pädagogik 3. eine polit-ökonomisch orientierte, gesellschaftskritische Pädagogik Grundlage dieser Arbeit ist eine polit-ökonomisch orientierte Pädagogik, der Leistungsbegriff in der Pädagogik wird daher beschrieben und untersucht in seiner Abhängigkeit und Funktion der Leistungsgesellschaft. Hierbei wird der gesellschaftliche Leistungsbegriff in seiner Vielschichtigkeit und Widersprülichkeit kritisch untersucht. Die Leistung wird hauptsächlich verstanden als Ergebnis, Erfolg. In breiten Teilen der pädagogischen Literaturen ist ein solcher Leistungsbegriff anzutreffen, die synonyme Verwendung von Leistung und Erfolg. Leistung als Ergebnis von Tests, aber auch Leistung als Ergebnis des Schulunterrichts, wie sich in Klassenarbeiten oder in den Zeugnisnoten manifestiert. Zusammenfassend kann festgestellt werden, daß die Theorie von der Funktionalität der Schichtung sich ausrichtet auf die Verschleierung und Rechtfertigung der bestehenden sozialen Ungleichheiten. Es wird nun überdeutlich, daß das Leistungsprinzip seine Funktion als statusgebender Faktor nicht sicher durchsetzen kann. Diese Frage ist schon problematisch im Hinblick auf die zugrundeliegenden theoretischen Voraussetzungen der Schichtungstheorie. Seinen egalitären Anspruch kann das Leistungsprinzip nur bei einer entsprechenden hohen sozialen Mobilität aufrechterhalten. Weder besteht aber hohe Mobilität im Hinblick auf die Schule, die in der modernen Gesellschaft einer der wichtigsten sozialen Dirigierungsstellen sein soll, noch im Hinblick auf das Einkommen. Soziale Mobilität ist nicht immer abhängig von Leistungswissen und Leistungskönnen, von funktionalen Fertigkeiten, sondern auch von normativen ideologischen, extrafunktionalen Fertigkeiten. Sozialer Aufstieg wird zur Prämierung konformen und gewünschten Verhaltens und damit zum betrieblichen Herrschaftsinstrument. Das Leistungsprinzip ist nur der scheinobjektive Schleier in diesem Sinne.

A Simulated Culture? : Cultural Learning Impact of the One-day Study Tour

Li-Jiuan Lilie Tsay,An-Wen Deng,Su-Yuan Lien 세계문화관광학회 2008 International Journal of Culture and tourism Resea Vol.1 No.1

One-day study tour in Taiwan began its establishment in early 2007, inspired by the An-San English Village in Seoul, in order to help students learn English quickly and efficiently. Different situational classrooms, such as a clinic, a hotel, a travel agency etc., are set up and manned with native teachers to teach students appropriate conversations accordingly. The main ideas of setting up such an English immersion program are to provide students with enough exposure to an English speaking environment and the culture related. In language learning, culture is one of the key elements which often determine students' learning interest and therefore cannot be neglected. In this study, based on the previous literature research, a model which suggests the relationships among learners' English ability (EA), learning interest (LI) and the situational classroom teaching (SCT) is discussed and explored. The purpose of the study is to investigate whether the simulated culture in different classroom settings could enhance students' English ability and their learning interest through the examination of the model suggested.

산부식전 소와 열구 처리법에 따른 치면 열구 전색재의 변연 봉쇄성에 관한 연구

安帥炫,金秀也,白秉周 全北大學校 齒醫學硏究所 1993 전북치대논문집 Vol.11 No.1

The purpose of this study was to evaluate the marginal sealing of pit & fissure sealant according to the treatment of pit & fissure prior to acid etching in permanent premolar & molar. 20 premolars & 30 molars were used for experiment. They were classified into 5 experimental group at random : Group 1 was not treatment and Group 2, 3, 4, 5 were respectively treatment with pumice, small round steel bur of low speed handpiece, pointed diamond bur of high speed handpiece, Murakami R.I. No. 1-2. All the specimens were then thermocycled in a range of 4℃∼54℃ and immersed in 2% methylene blue dye solution for 24 hours and sectioned with low speed diamond cutter into two part under water condition. All the specimens were observed at pit & fissure-sealant interface with light microscope & statistical analysis was performed. The obtained results were as follows ; 1. There were significant increase in marginal sealing of high speed handipiece-pointed diamond bur group in contrast to pumice group at significant level α=0.05 when compared by dye penetration score(P<0.05). 2. There were significant increase in marginal sealing of low speed handpiece-small round steel bur group, high speed handpiece-pointed diamond bur group and Murakami R.I. No 1-2 group in contrast to pumice group at significant level α=0.01 when compared by dye penetration score(p<0.01.) 3. There were significant increase in marginal sealing of low speed handpiece-small round steel bur group, high speed handpiece pointed diamond bur group and Murakami R.I. No. 1-2 group in contrast to pumice bur group and Murakami R.I. No. 1-2 group in contrast to pumice group at significant level α=0.01 when compared by dye penetration length(p<0.01). 4. When compared by dye penetration score, it is lowest in high speed handpiece-pointed diamond bur group and lower in low speed handpiece-small round steel bur group, Murakami R.I. No. 1-2 group, pumice group, no treatment group in sequence. 5. There were better penetration force of pit and fissure sealant in low speed handpiece-small round steel bur group and high speed hdndpiece-pointed diamond bur group than no treatment group, pumice group and Murakami R.I. No. 1-2 group.

Malonaldehyde 및 Hexanal의 DNA 損傷作用

崔守安 부산교육대학교 과학교육연구소 1990 科學敎育硏究 Vol.15 No.-

The damage of plasmid DNA by malonaldehyde and hexanal to elucidate the DNA damage mechanism by lipid peroxidation products was investigated through 1% agarose gel electrophoresis. DNA damage was induced by malonaldehyde and dexanal, byt its mechanism was due to the formation of the DNA-carbonyl compound complex, not to the scission of DNA strand. And there was not the effects of avtive oxygens on the DNA damage by malonaldehtde and hexanal.

Linoleic acid의 酸化에 의한 活性酸素種의 生成

최수안 부산교육대학교 과학교육연구소 1989 科學敎育硏究 Vol.14 No.-

The Formation of superoxide anion(·O_2^-)and hydrogen peroxide(H_2O_2) during linoleic acid peroxidation were investigated in linoleic acid-aqueous system at 37℃. Superoxide anion was rapidly generated in the early stage of peroxidation, marked to 0.375(absorbance at 560mm) in the 12mM linoleic acid(POV below 80millieq/kg) incubated for Ⅰ day and then decrased with time-elapsed. Hydrogen peroxide was also rapidly generated in the early stage of peroxidation regardless of linoleic acid concentration. And, superoxide dismutase (SOD) and catalase greatly inhibited the formation of superoxide anion and hydrogen peroxide, respectively.

植物油의 Triglyceride 組成에 관한 硏究 : 올리브기름의 Triglyceride 組成

최수안 부산교육대학교 과학교육연구소 1984 科學敎育硏究 Vol.9 No.-

Triglyceride fraction was separated from olive oil by thin layer chromatography (TLC) and fractionated into four groups by high performance liquid chromatography(HPLC). Compositions of the triglycerides and fatty acids of four fractions were determined by gas liquid chromatography(GLC). The olive oil contained higher concentrations of C-52 and C-54 triglycerides having partion numbers of 48. The fatty acid compositions of these triglycerides were mainly composed of C18:1 and C18:2 fatty acids. From these results, the possible fatty acid combinations of major triglycerides of olive oil were estimated to be (3C18:1;50.6%), (1C16:0, 2C18:1;23.51%), (2C18:1, 1C18:2;5.48%), (1C18:0, 218:1;4.55%), (1C16:0, 1C18:1, 1C18:2;2.94%), (2C16:0, 1C18:1;2.35%), (1C16:1, 2C18:1;2.21%), (1C18:1, 2C18:2;1.06%), (1C14:0, 2C18:1;1.03%).

미강유의 TG組成에 관한 硏究

崔守安 부산교육대학교 과학교육연구소 1983 科學敎育硏究 Vol.8 No.-

High performance liquid chromatography(HPLC) was applied to the anlaysis of triglycerides of rice bran oil. The tiglycerides were clearly separated in five peaks by HPLC on a column packed with μ-Bondapack C18 using methanol-chloroform mixture as a solvent. compositions of the triglyceride and fatty acid of the fraction was also analyzed by gas liquid chromatography(GLC). Each of these collected fractions gave three to four peaks in the GLC chromatograms according to the carbon number of the triglyceride. The fitty acid compositions of these triglycerides were mainly composed of C16:0, C18:1 and C18:2 fatty acids. The major triglycerides of the rice bran oil were found to be those of (C16:0, C18:1, C18:2;16.64%), (2xC18:1, C18:2;16.18%), (3xC18:1;13.7%), (C16:0, 2xC18:1;12.77%), (C18:1, 2xC18:2;9.16%) and (C16:0, 2xC18:2;6.42%)

추적관찰 중 종괴의 크기가 커진 경화성 혈관종 1례

안형수,장안수,이준혁,박성우,고은석,백상현,박재성,허균,신화균,박춘식 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

We report a case of a sclerosing hemangioma of the lung with increased size during follow up, a rare benign neoplasm of the lung. A 32-year-old woman had round increased opacity in right upper lobe on posteroanterior chest radiograph. That lesion has grown slowly over four years. Computed tomographic scan showed a well circumscribed lung mass in medial aspect of right upper lobe. Radiological differential diagnosis for the lesion included inflammatory pseudotumor, atypical carcinoid, lung cancer and localized fibrous tumor of pleura. Nonspecific findings were shown by the bronchoscopy and percutaneous transthoracic needle aspiration. Anterior and apical segmentectomy was carried out and the lesion was pathologically diagnosed as sclerosing hemangioma of lung.