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Stanley E. Gillilannd 대한보건협회 1987 대한보건연구 Vol.13 No.2
In order to an observation and fundamental study on the rate of water holding capacity for the meat hygiene in the samples of 224 Korean native cattle. After salughter, l0gm of the beef each was taken from chuck, rib, loin, rump, flank and round in order to measure water holding rate in percent. It is hope that the information will be used for reference in future endeavors of study in the field of Meat Hygiene in Veterinary Public Health and Food Hygiene in Public Health. The results were summarized as follows: 1) Results of water holding rate in the beef was 75.8±1.04% in Korean native cattle. 2) The mean value of water holding rate the parts of beef were 76.1±1.3% in chuck, 75.1±1.5% in rib, 75.4±0.7% in loin, 76.0±1.5% in rump, 75.5±1.4% in flank and 76. 5±1.5% in round, respectively. 3) The age and body weight gain of cattle showed the reverse proportion to water holding rate of beef(p<0.01). 4) There was a significant correlation(r=-0.558, P<0.01) between age and water holding rate of muscle(beef) in Korean native cattle and its induced regression equation was shown as the following: Y=78.02-0.631X(Y is water holding rate in %, X is age in year). 5) The correlation coefficient of body weight and water holding rate of muscle(beef) was r=-0.602(p<0.01) and the regression equation induced from it was : Y=80.679-0.012 X(Y is water holding rate in %, X is body weight in kg).
Stanley N. Caroff,Irene Hurford,Henry R. Bleier,Gregg E. Gorton,Cabrina Campbell 대한정신약물학회 2015 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.13 No.2
We describe a case of recurrent, life-threatening, catatonic stupor, without evidence of any associated medical, toxic or mental disorder. This case provides support for the inclusion of a separate category of “unspecified catatonia” in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) to be used to classify idiopathic cases, which appears to be consistent with Kahlbaum’s concept of catatonia as a distinct disease state. But beyond the limited, cross-sectional, syndromal approach adopted in DSM-5, this case more importantly illustrates the prognostic and therapeutic significance of the longitudinal course of illness in differentiating cases of catatonia, which is better defined in the Wernicke-Kleist-Leonhard classification system. The importance of differentiating cases of catatonia is further supported by the efficacy of antipsychotics in treatment of this case, contrary to conventional guidelines.
The Climbing Tower - Creating physical challenges for youth in a non-digital environment
Stanley K. Friesen,Grant Gehman 한국디지털디자인협의회 2014 (사)한국디지털디자인협의회 conference Vol.2014 No.5
Much of today’s entertainment for young people is based on electronic media ? from hand held games to multi-player immersive video environments. As a result, many children are not in good physical shape, and their view of reality is skewed by over stimulation visually, and under stimulation physically.
Stanley C. Igwe,Francesco Brigo 대한정신약물학회 2018 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.16 No.3
Atypical antipsychotics (AAPs) are increasingly used for the treatment of psychotic disorders but are known to be associated with metabolic abnormalities. This study is a systematic review and meta-analysis of randomized controlled trials (RCTs) studying the effectiveness of melatonin for the amelioration of AAP-induced metabolic syndrome. The MEDLINE (accessed via PubMed), Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials, PsycINFO, LILACS, CINAHL, and OpenGrey databases were searched for RCTs without language restrictions. Inclusion criteria were randomized, double-blind clinical trials comparing melatonin or melatonin agonists with placebo for the amelioration of AAP-induced effects at any age with selected components of metabolic syndrome as outcome measures. Two reviewers independently selected articles and assessed quality using Cochrane risk of bias and concealment tools. Of 53 records, five RCTs were eligible for the systematic review and three for the meta-analysis. The meta-analyses showed no statistically significant difference in any anthropometric or metabolic variable considered. Analysis according to psychiatric diagnosis from one RCT showed significant decreases in diastolic blood pressure (5.5 vs. −5.7 mmHg for the placebo and melatonin groups, respectively; p =0.001), fat mass (2.7 vs. 0.2 kg, respectively; p =0.032), and triglycerides (D) (50.1 vs. −20 mg/dl, respectively; p =0.08) in the bipolar group but not the schizophrenia group. Although limited to five RCTs with small sample sizes, evidence from RCT indicates that melatonin improves AAP-induced metabolic syndrome. This beneficial effect seems more significant in patients with bipolar disorder than those with schizophrenia. Further RCTs are needed to definitively establish the potential ameliorative effect of melatonin and to justify its efficacy as an add-on therapy to curtail AAP-induced metabolic syndrome.
Recent Advances in the Pharmacology of Tardive Dyskinesia
Stanley N. Caroff 대한정신약물학회 2020 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.18 No.4
Tardive dyskinesia (TD) is a syndrome of abnormal involuntary movements that follows treatment with dopamine D2-receptor antagonists. Recent approval of vesicular monoamine transporter-2 (VMAT2) inhibitors offers hope for reducing the impact of TD. Although these drugs represent a significant advance in patient care and a practical step forward in providing relief for patients with TD, understanding of the pharmacology of TD that could inform future research to prevent and reverse TD remains incomplete. This review surveys evidence for the effectiveness of VMAT2 inhibitors and other agents in the context of theories of pathogenesis of TD. In patients for whom VMAT2 inhibitors are ineffective or intolerable, as well as for extending therapeutic options and insights regarding underlying mechanisms, a review of clinical trial results examined as experimental tests of etiologic hypotheses is worthwhile. There are still compelling reasons for further investigations of the pharmacology of TD, which could generate alternative preventive and potentially curative treatments. Finally, benefits from novel drugs are best realized within an overall treatment strategy addressing the condition and needs of individual patients.