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Impact of the Clean Air Act on Air Pollution and Infant Health:
Soohyung Lee(이수형),Heesun Yoo(유희선),Minhyuk Nam(남민혁) 한국재정학회(구 한국재정·공공경제학회) 2018 한국재정학회 학술대회 논문집 Vol.2018 No.-
This paper examines the extent to which the 2005 Clean Air Act introduced in South Korea affected air pollution and infant health. To identify the causal effect, we exploit the time and geographical variations in the adoption of the Act between 2003 and 2006. During this period, the Clean Air Act indeed significantly reduced air pollutants. The PM10 level was reduced by 9 percent, leading to a 5 percent reduction in infant mortality.
Molecular Exchange Dynamics of Block Copolymers in Electrostatically Associating Systems
SooHyung Choi(최수형) 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.1
Micelles and hydrogels driven by electrostatically associative interactions have been widely investigated as the delivery vehicles of biological molecules and pharmaceutically active compounds because of excellent stimuli-responsiveness and hydrophilic interior. However, much less is known about the dynamics of molecular partitioning in the self-assembled structures, particularly molecular exchange aspects, yet this is the fundamental process to understand stimuli-responsiveness, structural stability and release of loading materials. In this study, molecular exchange dynamics of block copolymers in electrostatically associating micelles and hydrogels are addressed using model polyelectrolyte system. The results provide key parameters to regulate the exchange dynamics and further insights to harness macroscopic changes of structural and mechanical properties in the electrostatically driven systems.
Soohyung Lee,Inkyu Yoo,Jisoo Han,Wonchul Jung,Hakhyun Ka 한국동물생명공학회(구 한국동물번식학회) 2018 발생공학 국제심포지엄 및 학술대회 Vol.2018 No.06
Estrogen is essential for reproductive processes such as maturation of ovarian follicles, embryo implantation, placentation, lactation, parturition, sexual differentiation, and sexual behavior in females. Generally estrogen binds to nuclear receptors, estrogen receptor alpha (ERα) and beta (ERβ). Recently, novel estrogen receptor, G protein- coupled estrogen receptor 1 (GPER1), has been identified and shown to be expressed in the plasma membrane. However, the expression and regulation of GPER1 has not been determined in the female reproductive system in pigs. Thus, this study determined the expression of GPER1 in the endometrium during the estrous cycle and pregnancy in pigs. We obtained endometrial tissues from gilts on day (D) 0, D3, D6, D9, D12, D15 and D18 of the estrous cycle and on D12, D15, D30, D60, D90 and D114 of pregnancy, and chorioallantoic tissues on D30, D60, D90 and D114 of pregnancy. GPER1 mRNA was expressed in the endometrium during the estrous cycle and pregnancy in pigs. During the estrous cycle, GPER1 expression was higher in diestrus and proestrus than in estrus and metestrus. During pregnancy, GPER1 mRNA was high during the preimplantation period and low during mid- to late pregnancy. Expression of GPER1 was significantly higher on D15 of the estrous cycle than D15 of pregnancy. RT-PCR analysis showed that GPER1 mRNA was not detectable in conceptus on D12 and D15 of pregnancy. In chorioallantoic tissues, GPER1 mRNA increased toward term pregnancy. Endometrial explant culture study showed that the expression of GPER1 mRNA was down-regulated by increasing doses of progesterone but not affected by estradiol. In situ hybridization analysis showed that GPER1 mRNA was localized to luminal epithelial cells in the endometrium on D15 of estrous cycle. These results indicate that GPER1 mRNA is expressed in the endometrium during the estrous cycle and pregnancy in a stage- and pregnancy status-dependent manner, suggesting that GPER1 may play an important role in mediating estrogen actions of the maternal-fetal interface in pigs. Further analysis of signaling pathway and function of GPER1 in the reproductive system is needed.
Adsorption of acetaldehyde from air by activated carbon and carbon fibers
Soohyung Park,Muhammad Yaqub,Seunghan Lee,Wontae Lee 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.2
The adsorption of acetaldehyde from air using various activated carbon and carbon fibers was investigated in this study. These adsorbents included activated carbon (AC), carbon fibers (CFs), activated carbon fibers (ACFs), and metal-coated carbon fibers (MCCFs) supplied by different manufacturers. AC was categorized as AC₁, AC₂, AC₃, and AC₄, CFs were denoted as ACF₁, while ACFs and MCCFs were expressed as ACF₂ and ACF₃, respectively. Five composite materials were prepared using the AC and ACFs in different ratios, and experiments were conducted to assess their acetaldehyde adsorption efficiency under dry and wet conditions. The results showed that the acetaldehyde adsorption efficiency of an impregnated AC₄ was higher (95.9%) than that of both non-impregnated AC₁ and AC₃ and an impregnated AC₂ after 1 min of operation. ACF₂ showed a higher acetaldehyde adsorption efficiency (50.9%) as compared to ACF₁ and ACF₃ because of its larger surface area and selective absorption capability after 1 min of operation. A composite material comprising 6.3 g of AC₄ and 1 g of ACF₂ showed the highest adsorption efficiency of 97.9% under dry conditions. However, this adsorption efficiency significantly decreased under wet conditions.
Development of a New Analysis Framework for the SuperBelle Experiment
Soohyung Lee,원은일,Ryosuke Itoh 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.5
The analysis framework plays a key role in high energy physics experiments. A new framework is under development to advance the current analysis framework in the Belle experiment. The new framework supports complete object-oriented analyses. It also supports more powerful and efficient ways to manage parallel processing in all of symmetric multiprocess (SMP), network clusters, and grid computing system. In this paper, the current development status of the new framework is discussed, with emphasis on parallel processing. The analysis framework plays a key role in high energy physics experiments. A new framework is under development to advance the current analysis framework in the Belle experiment. The new framework supports complete object-oriented analyses. It also supports more powerful and efficient ways to manage parallel processing in all of symmetric multiprocess (SMP), network clusters, and grid computing system. In this paper, the current development status of the new framework is discussed, with emphasis on parallel processing.
Soohyung Lee,Yugyeong Cheon,Hakhyun Ka,Inkyu Yoo The Korean Society of Animal Reproduction and Biot 2022 한국동물생명공학회지 Vol.37 No.4
The cellular communication network factor (CCN) family proteins regulate many biological events such as angiogenesis, tumor growth, placentation, implantation, and embryogenesis. The expression and function of CCN1, CCN2, and CCN3 at the maternal-conceptus interface are established in humans and rodents, but little is known about the role of CCN4 to CCN6 in the reproductive organs in any other species. Several studies in transcriptome analysis in pigs have shown that the expression of CCN4 and CCN6 increases in the endometrium during early pregnancy. However, their expression, regulation, and function in the endometrium throughout the estrous cycle and pregnancy have not been fully understood in pigs. Thus, we determined the expression, localization, and regulation of CCN4 and CCN6 during the estrous cycle and at the maternal-conceptus interface in pigs. We found that the levels of CCN4, but not CCN6, changed during the estrous cycle. The levels of CCN4 were greater during mid- to late pregnancy than in the early stage, and the levels of CCN6 were greatest on Day 15 of pregnancy. CCN4 and CCN6 were detected in conceptus tissues during early pregnancy and in chorioallantoic tissues during the later stage of pregnancy. CCN4 mRNA was mainly localized to epithelial cells, CCN6 mRNAs to epithelial and stromal cells in the endometrium. In endometrial explant cultures, CCN4 expression was increased by progesterone, and CCN6 expression by interferon-𝛾. These results suggest that CCN4 and CCN6 may play roles in the establishment and maintenance of pregnancy by regulating the endometrial epithelial cell functions in pigs.
Efficient Neural Network Design for Identifying Potential Game Item Buyers
Soohyung Lee 한국지능시스템학회 2022 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.22 No.3
As competition in the mobile game market continues to intensify, the number of users accessingspecific games is decreasing, and marketing costs are rising significantly. Marketing methodsto increase average revenue per user (ARPU) are being improved accordingly. In this study,we present a method for predicting the future purchases of new users who start playingmobile games. The proposed system enables effective marketing based on the purchasingpropensity of a user over a short period of time. In the game data, the proportion of nonpurchasers compared to purchasers is extremely large because the number of purchasers issmall when the game is first released. Therefore, this study use an under-sampling methodto handle the unbalanced data. The loss functions used in neural networks are customizedto learn a neural network with a high probability that a predicted purchaser will be an actualpurchaser. Experiments show that proposed method can predict the purchasing propensityover a month-long period using the 7-day data of a new user.