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Sithara Suresh,Mostafa Ibrahim Waly,Mohammad Shafiur Rahman,Nejib Guizani,Mohamed Abdullah Badar Al-Kind,Halima Khalfan Ahmed Al-Issaei,Sultan Nasser Mohd Al-Maskari,Bader Rashid Said Al-Ruqaishi,Ahme 한국식품영양과학회 2017 Preventive Nutrition and Food Science Vol.22 No.4
Oxidative stress plays a pivotal role in the development of diabetes and hyperglycaemia. The protective effects of natural extracts against diabetes are mainly dependent on their antioxidant and hypoglycaemic properties. Broccoli (Brassica oleracea) exerts beneficial health effects in several diseases including diabetes; however, the mechanism has not been elucidated yet. The present study was carried out to evaluate the potential hypoglycaemic and antioxidant properties of aqueous broccoli extracts (BEs) in diabetic rats. Streptozotocin (STZ) drug was used as a diabetogenic agent in a single intraperitoneal injection dose of 50 mg/kg body weight. The blood glucose level for each rat was measured twice a week. After 8 weeks, all animals were fasted overnight and sacrificed; pancreatic tissues were homogenized and used for measuring oxidative DNA damage, biochemical assessment of glutathione (GSH), and total antioxidant capacity (TAC) as well as histopathological examination for pancreatic tissues was examined. Diabetic rats showed significantly higher levels of DNA damage, GSH depletion, and impaired TAC levels in comparison to non-diabetics (P<0.05). The treatment of diabetic rats with BE significantly reduced DNA damage and conserved GSH and TAC values (P<0.01). BE attenuated pancreatic histopathological changes in diabetic rats. The results of this study indicated that BE reduced the STZ mediated hyperglycaemia and the STZ-induced oxidative injury to pancreas tissue. The used in vivo model confirmed the efficacy of BE as an anti-diabetic herbal medicine and provided insights into the capacity of BE to be used for phytoremediation purposes for human type 2 diabetes.
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The Convexity Graph of Minimal Dominating Functions of a Graph
S. Arumugam,Sithara Jerry 장전수학회 2010 Proceedings of the Jangjeon mathematical society Vol.13 No.2
Let G = (V,E) be a graph. A function f : V → [0, 1] is a dominating function if ∑u∈N[v] f(u) ≥ 1 for all v ∈ V. A dominating function f is called a minimal dominating function (MDF) if any function g : V → [0, 1] with g < f is not a dominating function. If f is an MDF of G, then Pf = {v ∈V : f(v) > 0} is the positive set of f and Bf = {v ∈ V : ∑u∈N[v] f(u) = 1} is the boundary set of f. The relation defined on the set F of all MDFs of G by fpg if Pf = Pg and Bf = Bg is an equivalence relation which partitions F into a finite number of equivalence classes X1, X2, . . . , Xt. The convexity graph C(G) of G has {X1,X2, . . . ,Xt} as its vertex set and Xi is adjacent to Xj if there exist f ∈ Xi and g ∈ Xj such that any convex combination of f and g is an MDF of G. In this paper we determine the convexity graphs of some standard graphs. We also prove that the convexity graph of any connected graph contains K₃.
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Sulakkana Wanshapaly Rathnayake,Sithara Rasanjali Sirimanna,Chamari Thathsaramala Dissanayake 한국해양과학기술원 2022 Ocean science journal Vol.57 No.1
This study assesses the abundance of fish in different habitats of Negombo Lagoon, a human-influenced, highly productive tropical lagoon in Sri Lanka, and the effects of physico-chemical parameters on their abundance. Six different habitats, i.e., three mangrove habitats, seagrass bed associated habitat, brushpile, and mud and sand flat were selected as sampling sites representing three major areas, Kadolkele, Dungalpitiya, and Kepungoda. Fish were sampled using a drag net with a stretch mesh size of 50 mm and salinity, Surface Water Temperature, Dissolved Oxygen, pH, Nitrate–N and Orthophosphate were measured in each habitat from January to December 2018 by making monthly field visit. A total of 45 fish species belonging to 30 families were identified. The highest species abundance was reported in seagrass associated habitat, while the lowest was in Kadolkele mangrove habitat (p < 0.05; ANOVA) due to its low level of DO (1.92 mg dm−3) and high Orthophosphate (1.02 mg dm−3) content. Different life stages of fish shared different habitats and small juveniles were abundant in association with seagrass bed (67.09%) while mature ones were dominant (42.12%) in brushpile area. This study proves that the abundance of fish varies with different physico-chemical parameters and, according to the generalized additive model, the highest abundance of fish is in association with > DO of 4 mg dm−3, low level of Orthophosphate (0.5–0.75 mg dm−3), 0.5–1.5 mg dm−3 of Nitrate–N, and 20–30 ppt salinity. The findings of this study are important to understand the spatial and seasonal patterns of fish abundance in a tropical lagoon and how physico-chemical parameters affect their abundance.
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