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New fabrication process of silicon quantum dots using external laser irradiation
Jung Yup Yang,Jin Pyo Hong,Chae Ok Kim,Eun Kyu Kim,Hyun Jung Kim,Kap Soo Yoon,Seong Ki Min,Si Ok Shon,Young Ho Do,Young Ju Park 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.1
We present an ecient technique for the formation of silicon quantum dots (Si QDs) by exposing a Nd: YAG laser (wavelength = 355 nm) onto amorphous Si lm. Primary emphasis is placed on the simple and direct fabrication of the Si QDs without performing any micro or nano-patterning process. The scanned laser irradiation of low power causes localized segregation of as-deposited lm by the laser-induced heat, resulting in the fabrication of Si QDs. Observations in scanning electron microscope and atomic force microscope system clearly conrm highly uniform and controllable nanoscale Si QDs in our case. The average size and density of the Si QDs were about 4 nm and 1.5 1012/cm2, respectively. In addition, optical and electrical properties of the Si QDs were investigated by photoluminescence and C-V measurements. The experimental results suggest that our new process can lead to very stable optical and electrical devices, with well controllable and reproducible Si QDs.
Microalgae, Tetraselmis tetrathele has Alopecia Prevention and Scalp Improvement
( Si-hyang Park ),( Kyong-dong Lee ),( Ginnae Ahn ),( Hye-jin Park ),( Kap Seong Choi ),( Jiyeon Chun ),( Sun-yup Shim ) 한국미생물 · 생명공학회 2021 한국미생물·생명공학회지 Vol.49 No.4
The microalga, Tetrathelmis tetrathele, is used in the development of products for the aquaculture, food, and nutraceutical industries. In the present study, we investigated whether the T. tetrathele ethanolic extract (TTE), which has anti-inflammatory properties, can confer protection against alopecia and improve scalp health, influence the proliferation of human keratinocytes, HaCaT cells, and human hair follicle dermal papilla cells (HFDPC), or inhibit 5α-reductase activity. We found that TTE inhibited the production of the inflammatory mediator, nitric oxide (NO), and prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) without cytotoxicity in LPS-stimulated RAW 264.7 cells. In addition, TTE encouraged the proliferation of HaCaT cells and HFDPC. Our results showed that TTE had anti-inflammatory activities, proliferated HaCaT cells and HFDPC, and inhibited 5α-reductase activity. Therefore, we suggest that T. tetrathele could be a potent therapeutic agent for alopecia prevention and scalp improvement.
김시연,이규갑 중국어문학회 2001 中國語文學誌 Vol.9 No.-
南朝梁代顧野王編簒的 《玉篇》是中國第一部楷書字典, 其原本己佚. 淸末, 黎庶昌·羅振玉在日本發現 《玉篇》殘卷以後, 各自集佚成書刊行過. 1984年, 中華書局將羅本和黎本彙集影印, 以『原本玉篇殘卷』爲書名出版. 對羅本和黎本, 學術界至今只提及過$quot;有些不同$quot;, 但就具體之差異未曾有人深入硏究發表過. 本論文集中檢討了羅本和黎本所收的『原本玉篇殘卷·欠部』之字頭的字形及內容上的異同. 首先以羅本爲基本準繩, 詳細檢討了其字頭的字形, 總結出羅本所存在的重複字頭之原因大部分屬于字形的訛變現象與筆法之差 ; 再者, 通過對羅本和黎本的比較, 雖然黎本所修訂之處無不有誤, 發現黎本內容較爲準確, 幷其異同也多半屬於單純約異體字形, 其餘卽爲通假字或缺字補漏. 總之, 參照現有各種異體字典, 確認到兩本內所存在的訛變字形與筆法之差幷非『原本玉篇殘卷』內存在的特殊現象, 乃是隋唐宋代普遍存在幷使用的字形.
오갑진(Kap Jin Oh),최윤석(Yun Seuk Choi),최일식(Il Shik Choi),박시경(Si Kyung Park),이규흥(Kyou Heung Lee),정순간(Sun Gan Chung),조의환(Eui Hwna Cho) 대한약학회 1992 약학회지 Vol.36 No.5
Astilbes rhizoma has been used for headache, arthralgia, chronic bronchitis and stomachalgia in traditional chinese medicine. The analgesic activities and their components of Astilbe chinensis var. davidii Rhizomes were evaluated. The ether and ethylacetate fractions of 70% EtOH extract showed considerable analgesic activities by acetic acid induced writhing method. Compound 1~5 were isolated from ethylacetate fraction and identified as gallic acid, (+)-catechin, (+)-gallocatechin, bergenin and 11-O-galloylbergenin on the basis of spectroscopic methods. Among them (+)-gallocatechin showed stronger analgesic activity than that of other compounds.
이시훈,허갑범,이현철,임승길,차봉수,윤영훈,노태웅 대한내분비학회 2000 Endocrinology and metabolism Vol.15 No.4
Multiple endocrine neoplasia (MEN) is a combination of endocrine tumor associations and consists of 3 types : 1, 2A and 2B. Herein, we report a case of insulinoma which is combined with pheochromocytoma discovered at the left adrenal gland which was treated by surgical resection. We think there is a possibility of a new type of multiple endocrine neoplasia (MEN) (J Kor Soc Endocrinol 15:640-647, 2000)
이시훈(Si Hoon Lee),강은석(Eun Seok Kang),이광은(Kwang Eun Lee),김하동(He Dong Jin),최성희(Seung Hee Choi),김대중(Dae Jung Kim),안철우(Chul Woo Ahn),차봉수(Bong Soo Cha),임승길(Sung Kil Lim),이현철(Hyun Chul Lee),허갑범(Kap Bum Huh) 대한내과학회 2002 대한내과학회지 Vol.63 No.1
목적: 본 연구는 한국인 성인에서 인슐린저항성에 따른 대사증후군과 그 구성요소들의 유병률을 분석하기 위하여 수행하였다. 대상 및 방법: 한국건강관리협회에서 건강검진을 받은 30세 이상 성인 남녀 1,091명을 무작위로 추출하여 혈당, 혈청 인슐린, 총콜레스테롤, HDL-콜레스테롤, 중성지방, 체질량지수, 허리둘레, 혈압, 경동맥 내막중막두께 및 복부초음파를 시행하였고, 대상군을 인슐린저항성 정도에 따라 인슐린감수성군, 중간군, 인슐린저항성군으로 삼등분하여 그들의 임상 및 검사결과에 따라 대사증후군의 발병률을 분석하였다. 결과: 인슐린감수성군과 비교할 때, 인슐린저항성군에서 대사증후군의 상대위험도는 84.1배 증가하였고, 당뇨병 및 내당능장애는 10.2배, 고혈압은 1.8배, 이상지혈증은 2.8배, 고콜레스테롤혈증은 2.5배, 지방간은 3배 증가하였고, 전신성비만보다 복부비만이 인슐린저항성에 더 기여하는 것으로 나타났다. 결론: 본 연구는 단면적으로 수행되었으나, 인슐린저항성이 대사증후군의 중요한 위험인자이고, 심장혈관질 환을 비롯한 성인병의 예측인자로써 큰 의미가 있음을 시사한다. 따라서 성인병의 예방을 위해서 앞으로는 건강검진에 인슐린저항성을 평가하는 항목을 도입할 것을 권장한다. Background: This study was initiated to evaluate the prevalence of metabolic syndrome and its components as risk factors for cardiovascular disease according to insulin resistance in the Korean adult population. Methods: This study was conducted as a branch of the Korean Metabolic Syndrome (KMS) Study: 1,091 individuals aged 30 79 years participating in medical check-up in Korea Association of Health (KAH) were included in this study. We checked fasting blood sugar, fasting insulin, proinsulin, lipid profiles (total cholesterol, triglyceride, LDL-cholesterol, HDL-cholesterol), body mass index, waist circumference, blood pressure, carotid intima-media thickness (IMT) and abdominal ultrasonography. We divided all of the examinees into three groups (insulin sensitive, intermediate, resistant tertiles) according to their degree of insulin resistance and correlated this with the prevalence of metabolic syndrome. Results: The relative risk of metabolic syndrome was 84.1-fold higher in the insulin resistant tertile group compared to the insulin sensitive tertile group. Diabetes mellitus or impaired fasting glucose (IFG) was 10.2-fold; hypertension, 1.8-fold; dyslipidemia, 2.8-fold; hypercholesterolemia, 2.5-fold; fatty liver, 3.0-fold. Abdominal obesity rather than general obesity was more contributory to insulin resistance. Conclusion: Although this is a cross-sectional study, we can show that insulin resistance is one of the most-striking risk factors in metabolic syndrome and can be used as a predictor of cardiovascular diseases. Furthermore, we should monitor the healthy insulin-resistant population to prevent ongoing cardiovascular diseases. More prolonged data should be gained to refine the correlations of insulin resistance to metabolic syndrome.(Korean J Med 63:54-60, 2002)