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      • KCI등재

        Thermal effect of high-velocity particle impingements on coating quality in cold gas dynamic spray operations

        Si-Jia Dong,Jian Ye,Lin Zhu,Li Guo,Peter Jusu Moray,Wei-Lai Liu,Jun Sun,Tien-Chien Jen 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.7

        This investigation is aimed to evaluate thermal effects of the high-velocity particle impingement on the coating quality in CGDS (cold gas dynamic spray). To achieve this, the authors used an explicit time integration approach to predict interface temperatures and deformation profiles of the substrate, as well as, their relationship in commercial solver ABAQUS 6.13. Copper (Cu) and aluminum (Al) materials were specified to particle and substrate, respectively. Two essential process parameters, including six different impact velocities (300, 400, 500, 600, 700, 800 m/s) and three different particle sizes (1, 5, 15 μm), were involved in all simulations. There are very good agreements between the simulated and the published that the non-uniform interface temperature and the poor/failure particle deposition have the direct relationship with either impact velocity or particle size. Once again this study strongly demonstrates the thermal effect of the high-velocity particle impingement on coating quality in CGDS, in turn providing insights into process parameter selection.

      • Treaty-Port English in Nineteenth-Century Shanghai: Speakers, Voices, and Images

        Jia Si 고려대학교 민족문화연구원 2013 Cross-Currents Vol.- No.6

        This article examines the introduction of English to the treaty port of Shanghai and the speech communities that developed there as a result. English became a sociocultural phenomenon rather than an academic subject when it entered Shanghai in the 1840s, gradually generating various social activities of local Chinese people who lived in the treaty port. Ordinary people picked up a rudimentary knowledge of English along trading streets and through glossary references, and went to private schools to improve their linguistic skills. They used English to communicate with foreigners and as a means to explore a foreign presence dominated by Western material culture. Although those who learned English gained small-scale social mobility in the late nineteenth century, the images of English-speaking Chinese were repeatedly criticized by the literati and official scholars. This paper explores Westerners’ travel accounts, as well as various sources written by the new elite Chinese, including official records and vernacular poems, to demonstrate how English language acquisition brought changes to local people’s daily lives. I argue that treaty-port English in nineteenth-century Shanghai was not only a linguistic medium but, more importantly, a cultural agent of urban transformation. It gradually molded a new linguistic landscape, which at the same time contributed to the shaping of modern Shanghai culture.

      • KCI등재

        An Elastic Modulus Developing Model of Fly Ash Concrete under Sustained Load

        Si-yi Jia,Ming-hui Liu,Bing Han,Hui-bing Xie 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.7

        This paper focuses on the developing rule of elastic modulus of Fly Ash Concrete (FAC) under sustained load. Mechanism of theaction of sustained load on concrete is discussed and a new model for the elastic modulus of FAC is constructed based on the TriplephaseSpherical Model (TSM). An experiment with three concrete mix designs and five testing groups were conducted. Theexperimental compressive strength and elastic modulus at six different ages were used to calibrate the parameters in the model. Influences of two important parameters (loading age and loading level) in the model were analyzed. Test data confirmed the fact thatelastic modulus for the loaded concrete have a small increment compared to the non-loaded, which is more evident for youngerconcrete, and calculation results showed that the newly constructed model can well predict the elastic modulus of concrete undersustained load. Besides, compared to the loading age, the loading level was proved to be a more important factor in deciding thedevelopment rule of elastic modulus for the loaded concrete.

      • KCI등재

        탄소 배출량에 대한 중국 저탄소 경제의 분석

        진사가(Si Jia Chen),안종창(Jong-Chang Ahn) 한국산학기술학회 2019 한국산학기술학회논문지 Vol.20 No.7

        본 연구는 중국이 저탄소 경제를 제안한 지 10 여년이 지난 1985년부터 2016년까지의 중국의 탄소 배출과 탄소 배출에 영향을 주는 요인에 대해 분석한다. 중국은 동 기간 동안 산업 발전이 빠르게 진행되었으며 탄소 배출과 관련된 여러 가지 문제가 나타났고, 이제 저탄소 경제가 중국 경제 발전의 주요 과제가 되었다. 본 연구는 저탄소 경제이론 및 산업계에 영향을 미치는 요인을 바탕으로 중국의 조사 연감에서 관련 데이터를 선택하였다. 시계열 모형을 사용하여 중국의 탄소 배출에 대한 영향요소를 분석하였다. 관련 산업의 혁신이 계속되면서 전기와 같은 그린에너지의 사용을 증가 시켰지만, 석탄은 여전히 소모된 에너지에서 가장 큰 비중을 차지하고 있다. 에너지 사용효율이 증가하고 산업연구 개발 투자 강도가 해마다 증가하였지만 탄소 배출도 매년 증가하고 있다. 탄소 배출에 영향을 미치는 가장 큰 요인은 산업이라는 고정관념이 있으나, 본 논문을 통해 중국의 탄소 배출에 대한 산업의 영향이 점차 감소하고 있음을 발견했다. 또한 공업에서의 탄소 배출을 통제하는 동시에 기술개발을 계속 향상시키고, 다른 업종의 탄소 배출도 중시해야 하는 것이 전체 탄소 배출을 감소시키기 위해 필수라는 점을 발견하였다. 실증연구 결과를 기반으로, 데이터의 본질부터 시작하여 고정관념을 바꿀 수 있다면 저탄소 지속발전 경제에 좀 더 빨리 도달하게 될 것이다. This study analyzes the factors affecting China’s carbon emissions from 1985 to 2016. In recent years, the whole industries of China are in the midst of industrialization and have several problems. Now, the low-carbon economy has become the main task of China’s economic development. This study analyzes the factors affecting China’s carbon emissions by selecting relevant data onto the Chinese yearbook and using a time series model. The analysis shows that related industries continue to innovate and increase the use of green energy such as electricity, but coal is still the largest share of the energy consumed. As energy use efficiency increases and industrial R&D investment increases year by year, carbon emissions are increasing every year. In addition, there is a stereotype that industry is the biggest factor affecting carbon emissions. The research found that the impact of the industry on China’s carbon emissions is declining gradually. While controlling industrial carbon emissions, keeping continue to improve technology development and focusing on carbon emissions from other industries are critical to reduce overall carbon emissions. Based on the empirical results, if we can change stereotypes starting from the nature of the data, we will quickly reach a low carbon sustainable development economy.

      • KCI등재
      • KCI등재

        Chinese herbal medicine for myasthenia gravis: A systematic review and meta-analysis of randomized clinical trials

        Zhu Si-jia,Wang Rui-ting,Yu Ze-yu,Zheng Ruo-Xiang,Liang Chang-Hao,Zheng You-you,Fang Min,Han Mei,Liu Jian-ping 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.2

        Background: Myasthenia Gravis (MG) is a disorder of neuromuscular transmission bringing mild ocular weakness to severe generalized muscle weakness and disability. The conventional treatments have longterm side effects, and Chinese herbal medicines (CHM) have shown possible effect and safety for MG patients, but the existing evidence was not robust enough and the results were out of date. Methods: Searching for randomized controlled trials (RCTs) was conducted in 7 databases and clinical trial registries until July 2021. The Risk of Bias (ROB) 2 tool was used to assess the study quality and GRADE was used to assess the quality of whole evidence. Meta-analyses were conducted and the results were presented as risk ratio (RR) or mean difference (MD) with 95% confidence interval (CI). Results: Nineteen RCTs (1283 participants) testing 13 kinds of CHM with adequate randomization were included and six RCTs investigating Compound Huangqi were included in the meta-analyses. In addition to conventional treatment, nine CHMs reduced symptom scores of MG. Compound Huangqi plus conventional treatment (pyridostigmine bromide or prednisone or both) reduced the symptom scores compared with conventional treatment (MD=-3.56, 95%CI -4.86 to -2.26). Less adverse events happened in the CHM groups (3/247 in the CHM groups, 52/245 in the control groups, RR=0.13, 95%CI 0.06 to 0.30, 9RCTs, a total of 492 participants). The effect on quality of life was inconsistent. Conclusion: Nine CHMs could probably bring benefit for MG symptom improvement. Moderate to low certainty of evidence supported Compound Huangqi added-on conventional treatment probably bring extra benefit of improving MG symptoms. Adding CHMs could be safer than giving only conventional treatment. Study registration: The protocol was registered in PROSPERO (CRD42016032718).

      • KCI등재

        Polymorphisms in TYMS for Prediction of Capecitabine-Induced Hand-Foot Syndrome in Chinese Patients with Colorectal Cancer

        Si-Qi Dong,Tong-Min Wang,Jiang-Bo Zhang,Yong-Qiao He,Wen-Qiong Xue,Zi-Yi Wu,Da-Wei Yang,Lian-Jing Cao,Jing-Wen Huang,Xi-Zhao Li,Pei-Fen Zhang,Xiao-Hui Zheng,Wei-Hua Jia 대한암학회 2021 Cancer Research and Treatment Vol.53 No.3

        Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate synthase (TYMS) plays a key role for 5-fluorouracil metabolism and has been associated with some side effects caused by capecitabine. The aim of our study is to identify the possible genetic predictors of capecitabine-induced HFS (CAP-HFS) in Chinese colorectal cancer patients.Materials and Methods Whole exons of TYMS were sequenced for 288 extreme phenotype HFS patients, including 144 severe or early-onset (first 2 cycles) moderate HFS extreme cases and 144 extreme controls with no reported HFS. The associations between polymorphisms and CAP-HFS were analyzed using logistic regression under an additive model.Results We identified a novel risk mutation (c.1A>G, chr18:657743), was associated with severe HFS in an extreme case who was affected during the first cycle of treatment. Moreover, we identified three new variants, rs3786362, rs699517, rs2790, and two previously reported variants, 5’VNTR 2R/3R and 3′-untranslated region 6-bp ins-del, which were significantly associated with CAP-HFS (p < 0.05). In silico analysis revealed that the effect of these polymorphisms in the TYMS region on the development of HFS might not be restricted solely to the regulation of TYMS expression, but also the TYMS catalytic activity through the indirect effect on ENOSF1 expression.Conclusion This study identified new polymorphisms in TYMS gene significantly associated with CAP-HFS, which may serve as useful genetic predictors for CAP-HFS and help to elucidate the underlying mechanism of HFS.

      • SCOPUSKCI등재

        Molecular Spinless Energies of the Morse Potential Energy Model

        Jia, Chun-Sheng,Cao, Si-Yi Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.11

        We solve the Klein-Gordon equation with the Morse empirical potential energy model. The bound state energy equation has been obtained in terms of the supersymmetric shape invariance approach. The relativistic vibrational transition frequencies for the $X^1{\sum}^+$ state of ScI molecule have been computed by using the Morse potential model. The calculated relativistic vibrational transition frequencies are in good agreement with the experimental RKR values.

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