Curcumin protects against the intestinal ischemia-reperfusion injury: involvement of the tight junction protein ZO-1 and TNF-α related mechanism

Shuying Tian,Ruixue Guo,Sichen Wei,Yu Kong,Xinliang Wei,Weiwei Wang,Xiaomeng Shi,Hongyu Jiang 대한생리학회-대한약리학회 2016 The Korean Journal of Physiology & Pharmacology Vol.20 No.2

Present study aimed to investigate the effect of curcumin-pretreatment on intestinal I/R injury and on intestinal mucosa barrier. Thirty Wistar rats were randomly divided into: sham, I/R, and curcumin groups (n=10). Animals in curcumin group were pretreated with curcumin by gastric gavage (200 mg/kg) for 2 days before I/R. Small intestine tissues were prepared for Haematoxylin & Eosin (H&E) staining. Serum diamine oxidase (DAO) and tumor necrosis factor (TNF)-α levels were measured. Expression of intestinal TNF-α and tight junction protein (ZO-1) proteins was detected by Western blot and/or immunohistochemistry. Serum DAO level and serum and intestinal TNF-α leves were significantly increased after I/R, and the values were markedly reduced by curcumin pretreatment although still higher than that of sham group (p<0.05 or p<0.001). H&E staining showed the significant injury to intestinal mucosa following I/R, and curcumin pretreatment significantly improved the histological structure of intestinal mucosa. I/R insult also induced significantly down-regulated expression of ZO-1, and the effect was dramatically attenuated by curcumin-pretreatment. Curcumin may protect the intestine from I/R injury through restoration of the epithelial structure, promotion of the recovery of intestinal permeability, as well as enhancement of ZO-1 protein expression, and this effect may be partly attributed to the TNF-α related pathway.

Macroscopic Zn-doped a-Fe2O3/graphene aerogel mediated persulfate activation for heterogeneous catalytic degradation of sulfamonomethoxine wastewater

Shuying Dong,Xuanxuan Yan,Wenli Li,Yafei Liu,Xiaoxu Han,Xiaodan Liu,Jinglan Feng,Chongfei Yu,Chunyan Zhang,Jianhui Sun 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.108 No.-

In order to obtain a robust, durable and efficient heterogeneous catalyst, macroscopic monolithic Zndopeda-Fe2O3/graphene aerogel (GA) hybrid architecture with integrated morphology and hierarchicallyporous structure were controllably synthesized via a facile in-situ hydrothermal method and then used aspersulfate (PS) activator for sulfamonomethoxine (SMM) wastewater purification. Several key reactionparameters including the initial SMM concentration, reaction temperature, coexisting inorganic anionsand SMM in real natural water samples had different influence on the SMM removal efficiency. The catalyticefficiency of Zn-doped a-Fe2O3/GA with the molar ratio of Fe/Zn = 2:1.5 was about 66%, 62%, 66%and 11%33% higher than that of GA, a-Fe2O3/GA, Zn/GA and other Fe/Zn molar ratio. The improvedactivity of Fe/Zn = 2:1.5 benefits from the synergistic effects of the sp2 hybridized carbon and porousframework, as well as the surface oxygenic functional groups, which accelerate the pollutant/oxidant dispersionand electron transfer. Electron paramagnetic resonance results indicate that OH, 1O2 and SO4radicals account for the catalytic degradation of SMM and the activation of PS in present system is differentfrom conventional homogeneous systems, and speculate mechanism was proposed based on theobtained data.

Chinese female desire, gaze, and identity construction: A case study of “Boys Love”

Liang Shuying 이화여자대학교 아시아여성학센터 2022 Asian Journal of Women's Studies(AJWS) Vol.28 No.3

In recent years, there are few studies on Chinese female identity construction, female gaze, and sexual desire, as seen via the consumption of Boys Love (BL) media, or the tanbi genre. Drawing on Bourdieu’s concept of habitus and Deleuze’s idea of desire, this paper notes that expressions and alterations regarding sexual desire by Chinese female spectators are reflected in their imagined projections and consumption of BL media as part of their identity construction. These are situated in an imagined community of BL fans in Online Social Media (OSM). Using the trajectory of responses and exchanges of Chinese female audiences on the light Thai BL comedy, 2gether the Series (2020), which is introduced via fan-subtitling, I explore the dynamics of these female spectators as a case study. To a great extent, this represents a process of evolving their own gender values, sexual desires and identities through the consumption of BL media and writings based on the former. This paper thereby attempts to explore how Chinese female spectators project masculinity in homoeroticism and demonstrates that female identity construction is autonomous, proactive, and creative. Also reflected here are their strong beliefs in egalitarian love relationships, regardless of sexual preferences.

Curcumin protects against the intestinal ischemia-reperfusion injury: involvement of the tight junction protein ZO-1 and TNF-α related mechanism

Tian, Shuying,Guo, Ruixue,Wei, Sichen,Kong, Yu,Wei, Xinliang,Wang, Weiwei,Shi, Xiaomeng,Jiang, Hongyu The Korean Society of Pharmacology 2016 The Korean Journal of Physiology & Pharmacology Vol.20 No.2

Present study aimed to investigate the effect of curcumin-pretreatment on intestinal I/R injury and on intestinal mucosa barrier. Thirty Wistar rats were randomly divided into: sham, I/R, and curcumin groups (n=10). Animals in curcumin group were pretreated with curcumin by gastric gavage (200 mg/kg) for 2 days before I/R. Small intestine tissues were prepared for Haematoxylin & Eosin (H&E) staining. Serum diamine oxidase (DAO) and tumor necrosis factor (TNF)-${\alpha}$ levels were measured. Expression of intestinal TNF-${\alpha}$ and tight junction protein (ZO-1) proteins was detected by Western blot and/or immunohistochemistry. Serum DAO level and serum and intestinal TNF-${\alpha}$ leves were significantly increased after I/R, and the values were markedly reduced by curcumin pretreatment although still higher than that of sham group (p<0.05 or p<0.001). H&E staining showed the significant injury to intestinal mucosa following I/R, and curcumin pretreatment significantly improved the histological structure of intestinal mucosa. I/R insult also induced significantly down-regulated expression of ZO-1, and the effect was dramatically attenuated by curcumin-pretreatment. Curcumin may protect the intestine from I/R injury through restoration of the epithelial structure, promotion of the recovery of intestinal permeability, as well as enhancement of ZO-1 protein expression, and this effect may be partly attributed to the TNF-${\alpha}$ related pathway.

중국인 한국어 학습자의 사동 접미사 회피 전략 사용 양상 분석 : 말하기 과제를 중심으로

JIN SHUYING,이주희(JUHEE LEE) 학습자중심교과교육학회 2020 학습자중심교과교육연구 Vol.20 No.5

The purpose of this paper is to find the strategy of avoiding the use of ‘Causative suffix avoidance’ in situations where the use of Causative suffix is to be used and how this avoidance strategy showed depends on the level of the learner. To this end, six beginners, six intermediate, and six advanced Chinese learners were conducted in a speaking experiment designed in this study. As a result, the learners were using simple avoidance strategies, such as message abandonment, message reduction, message confrontation, and other grammar replacements, the use of the same vocabulary, approximations, use of synonyms, speaking synonyms, complementing self-correcting, complementing others, supplementing others’ corrections. The strategies used primarily for each level of learners are as follows. Students of beginner level are mainly use ‘to give up the message strategy’(48%), the intermediate level used ‘to other grammar strategy’ (21%) and ‘the self-correcting strategy’(20%). Finally the advanced level of students used ‘to other grammar replacements strategy’(37%) most. 본고는 중국인 학습자들을 대상으로 말하기 과제를 통해 사동 접미사를 사용해야 하는 상황에서 사동 접미사의 사용을 어떻게 회피하는지 그 전략을 파악하고, 이러한 회피 전략 양상이 학습자의 수준에 따라 어떻게 달라지는지를 파악하는 것을 목적으로 한다. 이를 위해 초급 6명, 중급 6명, 고급 6명의 중국인 한국어 학습자를 대상으로 본 연구에서 직접 고안한 말하기 실험을 시행하였다. 그 결과 사동 표현의 회피 양상은 메시지 포기, 메시지 축소와 같은 단순 회피 전략과 기타 문법 대체, 동일 어휘 사용, 근사어 사용, 유사음 사용, 풀어 말하기, 자기 수정 보완, 타인 수정 보완과 같은 회피의 보상 전략으로 나타났다. 학습자의 수준별로는 초급은 메시지 포기(48%), 중급은 기타 문법 대체(21%)와 자기 수정 보완(20%), 고급은 기타 문법 대체(37%)를 주된 회피 전략으로 사용하고 있는 것을 확인할 수 있었다.

김소월의 한시 번역 방법에 대한 고찰

朴曙穎(PU SHUYING) 한국어교육연구학회 2021 한국어교육연구 Vol.- No.15

김소월의 시세계는 크게 비극의식과 허무의식으로 나타나는데 이는 유년시절에 목격한 아버지의 실성이 주요 원인이다. 한편 숙모인 계희영이 들려주었던 민요·민담·설화 등은 그의 시편에 드러나는 여성적 정한이나 민요조 율격으로 표출되어 사람들의 공감을 얻을 수 있는 기반이 되었다. ‘님’이 떠나 한이 맺힌 여인, 길 잃음, 고향 잃음, 삼수갑산, 무덤 등을 통해 현세적이고 절망적인 허무주의 의식을 표출하였다. 김소월은 유고시를 포함하여 총 16편의 한시를 번역하였는데 전반적인 시세계는 창작시와 유사하다. 번역시의 내용은 대부분 ‘님’과의 이별과 사별로 인한 그리움, 고향 상살로 인한 허무함을 노래하고 있다. 그는 한시를 번역함에 있어서 창작시의 형식을 고수하여 원시를 한국의 언어와 리듬으로 새롭게 탄생시켰다. 본고는 김소월 번역시의 전반적인 번역 양상을 살펴본 후 그의 번역시가 어떠한 번역 방법으로 이루어졌는지 탐구하고자 한다. Kim So-wol s poetry world is largely caused by a sense of tragedy and futility, which is mainly due to his father s insanity, which he witnessed as a child. Meanwhile, folk songs, folk tales, and folk tales, which were told by his aunt, Gye Hee-young, were expressed through female Jeong-han and folk songs in his psalms, providing the basis for people to sympathize with. Nim has left and expressed a sense of modern and hopeless nihilism through the loss of a woman, lost her home, lost her hometown, Samsugapsan Mountain, and tombs. Kim So-wol translated a total of 16 Chinese poems, including the poems of Yougu, and the overall poetry is similar to the poems of creation. Most of the translation poems are about the longing for parting with nim and the loss of hometown. In translating Chinese poems, he stuck to the form of creative poetry and created primitive poetry in Korean language and rhythm. After looking at the overall translation aspects of Kim So-wol s translation, this paper wants to explore how his translation was done.

중국에서의 한국 문학 수용 연구

박서영(PU SHUYING) 한국어교육연구학회 2018 한국어교육연구 Vol.- No.8

문학 작품에는 어휘, 표현, 문법적인 요소뿐만 아니라 소통 및 이를 밑받침하고 있는 사회문화적 요소들을 포함하고 있다. 그러므로 문학 작품 속에는 언어적 가치가 있을 뿐만 아니라 그 언어를 사용하는 나라의 사회적 문화, 풍습, 사람들의 정서에 대하여 이해할 수 있는 가치가 있다. 문학 작품을 통해서 의사소통 능력과 사회 문화 인지능력이 동시에 향상됨으로써 문학 학습은 개인의 전반적인 실력을 높일 수 있는 가장 빠른 방법이라고 해도 과언이 아니다. 문학 번역은 그 나라의 언어와 문화를 가장 직접적으로 체험하고 전면적으로 부딪칠 수 있는 방법이라고 할 수 있다. 그러므로 한국어교육에서 문학 번역은 언어뿐만 아니라 한국의 문화와 문학을 교육할 수 있는 효과적인 방법이 될 수 있다. 나아가 중국 내에서 한국 문학 인지도 향상에도 역할을 할 수 있을 것으로 본다. Literary works include communication and social and literary elements that bear it out as well as words, expressions, and grammatical elements. Therefore, there are verbal value and value that people can understand social culture, custom, and emotion of the people who use the languages in the literary works. It is no exaggeration to say that cultural learning is the fastest method to be able to improve individuals general ability as their communicative competence and cognitive ability of society and culture are simultaneously done through the literary works. Literature translation can be the method to be able to experience the countries languages and cultures most directly and encounter them completely. Therefore, literature translation can be the effective method to be able to educate cultures and literature as well as the language in Korean language education. And furthermore, it can play a role in improvement of Korean literature awareness in China.

감사에 대한 응답 화행의 전략 사용 양상 연구 -한국인 모어 화자와 중국인 한국어 학습자의 비교를 중심으로-

김주영 ( Jin Shuying ) 겨레어문학회 2020 겨레어문학 Vol.65 No.-

본고에서는 감사에 대한 응답 화행에서 한국인 모어 집단을 비교의 기준으로 삼고 중국인 한국어 학습자 집단을 비교의 대상으로 구어 DCT 실험을 시행하여 학습자 집단의 숙달도별 전략 양상과 모국어 집단의 전략 양상을 살펴보았다. 현실에 가까운 상황을 설정하기 위해 한국과 중국의 영화 말뭉치를 분석하고 SAQ를 실시하여 요청의 여부에 따라 ‘호의형’과 ‘부탁형’으로 상황을 나누고, ‘사회적 지위’, ‘사회적 거리’, ‘부담 정도’에 따라 구어 DCT 설문 문항을 구성하였다. 분석 틀은 언어 표현에서 상위 전략으로 ‘인정, 겸손, 회피, 부정적 반응’, 하위 전략은 ‘수락, 상호 감사, 기쁨 표현, 호의 표시, 보답 요구, 농담, 부인, 당위성 강조, 화제 전환, 인사, 칭찬 및 격려, 불만’으로 설정하고 행동 표현으로는 수락과 거절로 설정하였다. 연구 결과 CKL은 ‘부인’ 전략을 전체 전략의 절반 이상을 사용하는 반면 KNS는 30%쯤 사용했으며 기타 전략의 사용율이 CKL에 비해 높다. 또한, 상대의 지위가 동등하거나 낮을 때 KNS는 ‘수락’ 전략을 선호하나 CKL은 ‘부인’ 전략이 압도적으로 높아 격식을 더 차리는 모습을 볼 수 있었다. This article examines the usage of expression of gratitude response for Chinese Korean learners comparing to native Korean speakers through Oral Discourse Completion Test (DCT). In order to be more realistic, the corpus of movies in Korean and Chinese was analyzed and verified by Self Assessment Questionnaire (SAQ). The questionnaire was composed of two contexts of gratitude expression: request-type response of gratitude and favor-type response of gratitude; and three social variables: social power, social distance and degree of burden. In the research framework, The strategies of expression of gratitude response include “acknowledgement, humility, avoidance and negative response” and more specific strategies include “acceptance, expressing gratitude each other, expressing delight, favor, request, humor, denial, emphasizing duty, changing the topic of conversation, greetings, compliment, encouragement an d dissatisfaction”. Two types of behavior expression have been set up: acceptance and rejection. The research findings show that the usage rate of “deny” accounts for more than half of all strategies for Chinese Korean learners (CKL), but about 30 per cent for Korean native speakers (KNS), and the rate of usage of other strategies for KNS is higher than that of CKL. In addition, when the status of counterpart is equal or lower than speakers, KNS could choose the strategy of “acceptance”, while, for CKL, the possibility of choosing “denial” is overwhelmingly high. It is shows that the CKL is prefer to formal expression.

<思母曲> 정서적 계승에 대한 고찰

朴曙颖(PU SHUYING) 한국어교육연구학회 2020 한국어교육연구 Vol.- No.12

<사모곡>은 폭넓은 해석의 가능성을 지니고 있지만 그 일차적 풀이는 대개 어머니에 대한 그리움으로 의견을 같이 한다. <사모곡>에 나타난 ‘효’의 문제는 한민족에게 있어서 시대를 뛰어넘는 보편적 정서이고 ‘사모곡’은 한국 문학에 있어서 영원히 변치 않을 제재이다. ‘어머니에 대한 그리움’이라는 보편적인 주제는 다양한 양상으로 계승되면서 저마다의 독자성을 갖추고 있다. <사모곡>의 정서적 계승은 크게 민요, 대중가요, 시적 측면에서 찾아볼 수 있는데 이는 결국 한 개인이 아니라 궁극적으로 한국적 정서의 한 원형을 그리고 있다. 본고는 <사모곡>의 계승을 살펴보기 위해 먼저 <사모곡>의 내용을 분석한 후 정서적 계승 양상에 대해 정리해 보고자 한다. Even though <Samogok> could be interpreted variously, the primary interpretation of it is mostly concluded in longing for mother. The matter of ‘filial duty’ shown in <Samogok> is the universal sentiment of the Korean people beyond times, and ‘Samogok’ is an everlasting material in Korean literature. The universal theme of ‘longing for mother’ has established its own identity as it is succeeded as various aspects. The sentimental succession of <Samogok> could be largely found in the aspect of folk song, popular song, and poetry, which eventually draws an original form of Korean sentiments instead of individuals’. In order to examine the succession of <Samogok>, this thesis aims to summarize the aspect of sentimental succession by analyzing the contents of <Samogok>.

Investigation of the Dynamic Characteristics of Muck during EPB Shield Tunnelling in a Full Chamber Model Using a CFD Method

Jiazheng Zhong,Shuying Wang,Pengfei Liu,Zhengri Liu,Tao Xu 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.9

For the safety and efficiency of earth pressure balance (EPB) shield tunnelling, the dynamic characteristics of the muck in the excavation chamber and the screw conveyor should be considered. However, the velocity and pressure distribution of the muck in the EPB shield, reflecting muck flowability and face stability, are rarely observed at the jobsite. Therefore, a computational fluid dynamics (CFD) model with a modified inlet boundary was established to investigate the muck characteristics in the chamber and the screw conveyor during tunnelling in a full chamber mode. A compressible Bingham model was adapted to describe the muck compressibility and rheology. The time-dependent tunnelling parameters obtained from the simulation excellently matched the field-measured data. The simulation results show the non-uniform velocity distribution of the muck at the excavation face and the low-velocity zones where clogging potentially occurs. The muck pressure reaches a peak at the excavation face and then decreases along the cutterhead openings, chamber and screw conveyor for inflow. The simulation also captures the pressure imbalance at the cutterhead and bulkhead, which may destabilize the excavation face. The proposed discharge efficiency is 56.7% in the simulated condition, indicating that tunnelling with these muck properties has no risk of muck spewing.