膀胱의 單臟器成 Shwartzman反應에 관한 超微形態學的 硏究

권민아,장세국,서인수,손태중 慶北大學校 醫科大學 1990 慶北醫大誌 Vol.31 No.4

본 연구는 감염성 방광염의 성립의 조건으로 Shwartzman반응의 기전이 참여할 것인가를 검토하고, 방광의 단장기성 Shwartzman반응에서 초기의 형태적 변화를 알아보기 위하여 시도하였다. 실험은 백색 암컷 가토를 실험동물로 하여 방광내에 내독소를 주입하고 24시간후에 정맥내로 같은 내독소를 주사하여 야기조작 15및 30분, 1, 2 및 4시간후에 방광을 적출하여 육안, 광학, 주사전자 및 투과 전자현미경으로 관찰하였던 바 그 성적을 요약하면 다음과 같다. 광학 현미경으로는 반응의 초기부터 표재세포가 호산성 덩어리로의 변성 및 괴사 탈락이 나타나고, 중간세포 및 기저세포는 야기조작 수시간 후부터 공포성 변성을 보이고, 같은 시기에 상피하 미소혈관은 울혈 및 주변 조직의 부종을 보이고, 호중구의 침윤도 관찰되었다. 주사 전자현미경으로는 표재세포 표면의 microridge의 blurring과 표면구조의 편평화 및 세포간 결합장치의 이완등을 초기에서 부터 볼 수 있었고, 수시간이 지난 후에는 군데군데에서 상피의 괴사 탈락이 관찰되었다. 투과 전자현미경으로는 포재세포의 apoptosis를 초기에서부터 볼 수 있었고, 수시간 후에는 상피층 전층의 괴사까지 관찰되었고, 기저세포에는 autophage가 증가된 것이 관찰되었다. 가장 특징적 변화는 상피직하 점막하층 미소혈관계의 변화로 반응의 초기에서부터 내피세포의 종창등의 상해성 변화를 보였고, 수시간후에는 혈소판의 응집과 호중구의 변연화 및 유주등을 관찰할 수 있었다. 이상의 성적으로 보아 방광염의 성립에 Shwartzman반응의 기전이 참여할 수 있는 것으로 생각되며, 방광의 단장기성 Shwartzman반응의 주된 반응을 하는 장소는 상피직하부의 미소혈관계인 것으로 사료된다. This study was carried out to investigate the possible role of Shwartzman reaction in the development of the cystitis and the morphologic changes in early stage of the reaction. Endotoxin extracted from E. coli was injecting same endotoxin via ear vein, 24 hours after first infection. Animals were sacrificed 15 and 30 minutes, and 1, 2 and 4 hours after the last injection. The Urinary bladders were extracted out and examined with the light, transmision electron, and scanning electron microscopes. The results obtained were summarized as follows: Ligth microscopy showed eosinophilic degradation, necrosis and detachment of the superficial cells within 1 hour after provocation treatment. Intermediate and basal cells also showed swelling after few hours. Subepithelial microvasculatures showed congestion with perivascular edema and neutrophilic infiltration from the early stages. Scanning electron microscopy dischlosed blurring of microridge structures on superficial cells with loosening of the intercellular junction from early stage. Necrosis and detachment of epithelial cells were noted in several areas after few hours, only remaining basement membranes. Transmission electron microscopy showed apoptosis of the superficial cells, with partial necrosis through total thickness of the epithelial layer after several hours. Many autophagic vacuoles were found in basal cells. Characteristic vascular change was noted in the microvasculatures on the submucosa, consisting of swelling and archade formation of the endothelial cells with platelet aggregation, and margination and emigration of neutrophils. The results suggest that Shwartzman reaction could be participated on the development of cystitis, and subepithelial small vessels were the main focus of the reaction.

Exploring Information Warfare Strategies during the Russia–Ukraine War on Twitter

Shu–Min Hou,Wen-Cheng Fu,Shao–Yi Lai 한국국방연구원 2023 The Korean Journal of Defense Analysis Vol.35 No.1

Twitter, one of the mainstream social media platforms, has played a significant role in strategic communication and public diplomacy. Using tweets during the 2022 Russia–Ukraine war period as a case study, the researchers aim to build a pipeline that automatically detects information manipulation. Artificial intelligence and machine learning technology are adopted to target certain coordinated groups of people, and how they manipulate online public opinion internationally via social media platforms by retweeting identical tweets between members within the groups and even with their own tweets. With the large number of tweets posted and retweeted by the coordinated groups, their intended content will appear in the news feeds of normal users. This study maps an approach to future warfare that social media is becoming a vital part of information warfare to influence the results of conflict and regional relationships. The researchers argue that the government should consider taking countermeasures: 1) Set up legislation regarding media platforms and cooperate with social media companies to monitor manipulating behaviors. 2) Establish a model to orchestrate inter-agency defensive strategies. 3) Increase people’s media literacy to allow them to be aware of manipulative and collaborative behavior and decrease their likeliness to spread fake/manipulated information online unintentionally. Also, similar research can be adapted to different regional conflicts.

An experimental study of the effect of metal fiber filter pore size on deposition characteristics

Shu Zhang,Jung Min Seok,Soonho Song,Se Yong Lee,Kwang Min Chun 한국자동차공학회 2014 한국자동차공학회 부문종합 학술대회 Vol.2014 No.5

The Plant Genetic Diversity Conservation, Evaluation, Exchange and Utilization in China

Shu Min Wang 한국육종학회 2005 한국육종학회 학술발표회 발표요지 Vol.37 No.1

Development of Nested PCR, Multiplex PCR, and Loop-Mediated Isothermal Amplification Assays for Rapid Detection of Cylindrocladium scoparium on Eucalyptus

Tian-Min Qiao,Jing Zhang,Shu-Jiang Li,Shan Han,Tian-Hui Zhu 한국식물병리학회 2016 Plant Pathology Journal Vol.32 No.5

Eucalyptus dieback disease, caused by Cylindrocladiumscoparium, has occurred in last few years in largeEucalyptus planting areas in China and other countries. Rapid, simple, and reliable diagnostic techniquesare desired for the early detection of Eucalyptus diebackof C. scoparium prior to formulation of efficientcontrol plan. For this purpose, three PCR-based methodsof nested PCR, multiplex PCR, loop-mediatedisothermal amplification (LAMP) were developed fordetection of C. scoparium based on factor 1-alpha (tef1)and beta-tubulin gene in this study. All of the threemethods showed highly specific to C. scoparium. Thesensitivities of the nested PCR and LAMP were muchhigher than the multiplex PCR. The sensitivity of multiplexPCR was also higher than regular PCR. C. scopariumcould be detected within 60 min from infectedEucalyptus plants by LAMP, while at least 2 h wasneeded by the rest two methods. Using different Eucalyptustissues as samples for C. scoparium detection,all of the three PCR-based methods showed muchbetter detection results than regular PCR. Base on theresults from this study, we concluded that any of thethree PCR-based methods could be used as diagnostictechnology for the development of efficient strategiesof Eucalyptus dieback disease control. Particularly,LAMP was the most practical method in field applicationbecause of its one-step and rapid reaction, simpleoperation, single-tube utilization, and simple visualizationof amplification products.

Isolation and Characterization of Parthenogenetic Embryonic Stem (pES) Cells Containing Genetic Background of the Kunming Mouse Strain

Yu, Shu-Min,Yan, Xing-Rong,Chen, Dong-Mei,Cheng, Xiang,Dou, Zhong-Ying Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.1

Parthenogenetic embryonic stem (pES) cells could provide a valuable model for research into genomic imprinting and X-linked diseases. In this study, pES cell lines were established from oocytes of hybrid offspring of Kunming and 129/Sv mice, and pluripotency of pES cells was evaluated. The pES cells maintained in the undifferentiated state for more than 50 passages had normal karyotypes with XX sex chromosomes and exhibited high activities of alkaline phosphatase (AKP) and telomerase. Meanwhile, these cells expressed ES cell molecular markers SSEA-1, Oct-4, Nanog, and GDF3 but not SSEA-3 detected by immunohistochemistry and RT-PCR. The pES cells could be differentiated into various types of cells from three germ layers in vitro by analysis of embryoid bodies (EBs) with immunohistochemistry and RT-PCR, and in vivo by observation of pES cell-derived teratoma sections. Therefore, the established pES cell lines contained all features of mouse ES cells. This work provides a new strategy for isolating pES cells from Kunming mice, and the pES cell lines could be applied as the cell model in research into genomic imprinting and epigenetic regulation of Kunming mice.

문학 : 해외화문여작가여중화문화

탕숙민 ( Shu Min Tang ) 한국중국학회 2000 國際中國學硏究 Vol.3 No.-

≪臺灣日日新報≫ 中的 「南支南洋」 與 「臺灣籍民」 報導

종숙민 ( Shu Min Chung ) 東亞大學校附設 石堂傳統文化硏究院 2012 石堂論叢 Vol.0 No.52

본문은 ≪대만일일신보≫에 있는 「남지남양」과 「대만적민」에 관한 보도를 분석하는 것을 통해, 관방을 어느 정도 대표하는 신문이 드러낸 「식민주의」와 「지역주의」를 탐구했다. 그 결론이 지적하는 것은 다음과 같다; 1. 신문은 총독부의 「남지남양」 「남진」정책에 협력하여, 그 지역에 대해 대량으로 보도를 해서 재대(在臺) 일본인들이 중국 화남(華南)과 남양에 관해 인지하도록 했다. 이러한 일이 날마다 달마다 계속된 결과 대만은 「남지남양」에 대한 일본의 지식이 가장 보급된 곳이 되었을 뿐만 아니라, 「남지남양」 역시 연결되어 대만과 서로 관련있는 지역이 되었다. 2. 중국과 관련있는 뉴스를 대량으로 보도함으로써, 총독부가 봉쇄방식으로 대만과 본토(原鄕)의 교류를 단절시킨 것이 결코 아니었으며, 반대로 적극적으로 관제성 보도방식으로 대만 거주민들의 중국 인식을 주도했었음이 뚜렸이 나타난다. 예컨대 신해혁명 전후의 중국동란 보도는, 대만과 중국 사이에 있는 평온함과 동란을 강렬하게 대비시킴으로써, 총독부를 선전하는데 일정한 작용을 했다. 3. 일본어판과 중국어판의 보도내용은 완전히 똑같은 것이 아니었다. 본문을 예로 들면, 남양의 「신지식(新知)」에 대해서는 일본어를 읽을 수 없는 대만인은 인쇄문명과 지식전파를 향유하는 것에서 배제당했고, 제국 내부의 의견 충돌이나 기관 사이의 입장 차이에 관해서 식민지 인민들에게 엿보이는 것을 달가워하지 않았다. 일본어를 위주로 하고 중국어를 보조로 하는 경영방식 아래에서, 어떤 사람이 식민지의 이(異)종족을 지도할 수 있었는지, 어떤 사람을 일본어 구독능력을 갖춘 자로 한정지을 수 있는지는 계속 규명할 가치가 있는 과제이다. This article analyzes news reports by the The Taiwan Daily(Taiwan Nitiniti Shinpou) on "South China-South Seas(Nanshi Nanyou)" and "Taiwan Sekimin" and explores the "colonialism" and "regionalism" that appeared in the Japanese colonial government newspaper. My conclusions are as follows: (1) In cooperation with the Government-General of Taiwan`s policy of "southern advance" in "South China-South Seas," The Taiwan Daily reported extensively on these regions in order for Japanese in Taiwan to obtain information on South China and the South Seas. The accumulation of such reports not only transformed Taiwan into a base where Japanese knowledge on "South China-South Seas" was most widespread, but also resulted in closely linking the regions of "South China-South Seas" with Taiwan. (2) The extensive reporting of news on China demonstrated that the Government- General of Taiwan did not adopt a closed policy of severing exchange between Taiwan and mainland China; rather, it guided Taiwanese residents` understanding of China through an active and controlled manner of reportage. For example, newspaper reports on the upheavals in China around the time of the 1911 Xinhai Revolution no doubt served as colonial propaganda by emphasizing the stark contrast between a "peaceful Taiwan" and a "turbulent China." (3) Reportage in the Japanese-language edition and the Chinese-language edition of The Taiwan Daily was not necessarily the same. As in the case of "new knowledge" on the South Seas, those Taiwanese who could not read Japanese were excluded from a sphere of print culture and knowledge dissemination. Indeed, there were times when the colonial government did not want Taiwanese subjects to learn about discord within the Japanese empire or opposing stances among different political institutions. How the Government-General of Taiwan, under an administrative policy that prioritized Japanese-language over Chinese-language, guided its Taiwanese subjects and its Japanese-language readership is a question that deserves to be further researched.

도연명 ( 陶淵明 ) 및 기시 ( 其詩 )

왕숙민 ( Shu Min Wang ) 한국중국학회 1972 중국학보 Vol.13 No.1

사기명칭탐원 ( 史記名稱探源 )

왕숙민 ( Shu Min Wang ) 한국중국학회 1966 중국학보 Vol.5 No.1