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      • KCI등재

        Lateral Mass Screw Fixation in the Cervical Spine: Introducing a New Technique

        Rathinavelu Sreeramalingam,Islam Ariful,Shivhare Pankaj,Chatterjee Sandip 대한척추외과학회 2021 Asian Spine Journal Vol.15 No.6

        Study Design: This was designed as a randomized double blind study to compare the classical Magerl technique of insertion of lateral mass screws with the authors’ technique. The observations regarding length, outcome, and radiology was done by a group blinded to the technique used. Purpose: The present study was designed with the objective of identifying the optimal technique for introducing the lateral mass screws that uses the maximum possible dimension of the lateral mass. Overview of Literature: Lateral mass screw fixation is a common surgery that is performed in the cervical spine. Various modifications for the procedure have been described, such as changes in the entry point, angulation of the screws, and modifications in the exit point. These do not allow the insertion of longer screws that can give more purchase on the bone. Methods: From January 1, 2009 to December 31, 2018, 176 patients who were scheduled to undergo lateral mass screw fixation were enrolled. They were randomized into two groups; we inserted lateral mass screws using our new technique for one group and by using the classical Magerl technique for the other group. Intraoperative measurements were used to assess the bone-screw interface length. Postoperative radiography and postoperative computed tomography were performed to assess the trajectory of the screws. Results: Total 88 patients were included in the study group, including 68 men. The control group included 65 men. The most common indication for surgery was cervical spondylotic myelopathy. The average bi-cortical length that was measured intraoperatively was 19.9 mm in the study group and 16.3 mm in the control group. This was significantly different from the average lengths of screws in the control group. Conclusions: The trajectory that involves an entry point as close as possible to the posterior inferior medial angle of the lateral mass cuboid and traverses a distance of about 20 mm to obtain a bi-cortical purchase in the diagonally opposite angle may provide a much better and firmer bony purchase in the lateral mass than conventional points of entry and trajectories.

      • Free Vibration Analysis of Eccentric and Concentric Isotropic Stiffened Plate with Orthogonal Stiffeners using ANSYS

        Harun Rashid Siddiqui,Vaibhav Shivhare 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.12

        This paper shows the study of free vibration analysis of stiffened isotropic plates with orthogonal stiffeners placed eccentrically and concentrically to the plates. In this paper finite element model is developed in ANSYS parametric design language code and discretized using 20 node structural element (SOLID 186) and convergence study of isotropic stiffened plates has been performed and compare the results with related published literature. Effects of various parameters such as boundary conditions, aspect ratios, position of stiffeners eccentrically and concentrically to the stiffened plates has been studied. The vibration analysis of stiffened plate have been studied using Block -Lanczos algorithm. The results of non dimensional frequency of eccentric and concentric isotropic stiffened plate have been compare at different mode shapes, aspect ratio’s, boundary conditions using ANSYS.

      • Development of Artificial Intelligence Model for the Prediction of MRR in Turning

        Vinay Kumar Chaurasia,Dinesh Kumar Kasdekar,Vaibhav Shivhare 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.2

        In machining operations, the extents of important effect of the process parameters like speed, feed, and depth of cut are different for different responses. This paper investigates the effect of process parameters in turning of AA6061 T6 on conventional lathe. The problem appeared owing to selection of parameters increases the deficiency of turning process. Modeling can facilitate the acquisition of a better understanding of such complex process, save the machining time and make the process economic. Thus, the present work clearly defines the development of an artificial neural network (ANN) model for predicting the material removal rate. This study presents a new method to prediction the material removal rate (MRR) on a lathe turning Process. Firstly, Process parameters namely, Spindle speed, depth of cut and feed rate are designed using the Box behnken (DOE) was employed as the experimental strategy. The result shows that the ANN model can predict the material removal rate effectively. This approach helps in economic lathe machining.

      • KCI등재

        RP-HPLC method development using analytical QbD approach for estimation of cyanidin-3-O-glucoside in natural biopolymer based microcapsules and tablet dosage form

        Deepika Thakur,Ashay Jain,Gargi Ghoshal,U. S. Shivhare,O. P. Katare 한국약제학회 2017 Journal of Pharmaceutical Investigation Vol.47 No.5

        Anthocyanin has been proven to impart several health benefits and biological functions. Though, various analytical methods have been reported for single/multicomponent analysis of anthocyanins, found to be tedious, time consuming and difficult to reproduce. Analytical studies on specific anthocyanins for estimation using an approach of Analytical Quality by Design are scarce. USP method is only reliable for cyanidin-3-O-glucoside (CY-3- O-Glu) estimation, but exploring many disadvantage of having high buffer concentration in mobile phase system and gradient elution, hence column blockage. So there is need to develop a novel HPLC method to overcome this problem with the use organic solvents with lesser volume of buffer in isocratic mode of elution. The aim is to develop a robust and precise method for estimation of CY-3-O-Glu in biopolymer based microcapsules and tablets. The optimized method consisted of mobile phase containing solvent A and B, flow rate 0.8 mL/min with 20 min of analysis time. The method was further validated in accordance with current ICH guidelines Q2 (R1) and found to be highly selective for component in the presence of degradation products confirmed by Mass spectra. Therefore, the proposed method was found to be suitable for routine analysis of CY-3-O-Glu in food and pharmaceutical based formulations.

      • KCI등재

        Characterization and Functional Properties of Watermelon (Citrullus lanatus) Seed Protein Isolates and Salt Assisted Protein Concentrates

        Ali Abas Wani,Dalbir Singh Sogi,Preeti Singh,Uma Shankar Shivhare 한국식품과학회 2011 Food Science and Biotechnology Vol.20 No.4

        Watermelon (Citrullus lanatus) seed meal contains significant amount of extractable protein which can be used as nutritional and functional ingredients in food formulations. Alkali (0.1 M) and NaCl (0.5 M) were used to prepare protein isolates and concentrates from the defatted watermelon seed meals. Protein isolates reported protein yield of 35.15-38.27% and protein content (79.05-83.79%) which was significantly (p≤0.05) higher than the protein concentrates. SDS-PAGE of protein isolates and concentrates showed major polypeptides in the range of 74.72-110.42 kDa. Also, in vitro pepsin digestibility showed that most of the proteins were readily digested within 30 min of hydrolysis. Amino acids were dominated by arginine, aspartic, and glutamic acid. DSC results indicated that protein concentrates had significantly (p≤0.05) higher denaturation temperatures than protein isolates. The functional properties of concentrates in terms of solubility and surface properties were better than respective isolates. The results indicated that NaCl extracted proteins had comparatively better functional properties but their yield is significantly lower than respective protein isolates.

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