A Facile Hg2+-related Quenching Photoluminescence Sensor Based on Nitrogen-doped Graphene Quantum Dots

Shi-Man Du,Bing-Bing Shang,Xiao-Ru Zhang,Fu Feng,Sheng-Hui Zhang,Bao-Ping Qi 대한화학회 2020 Bulletin of the Korean Chemical Society Vol.41 No.9

A Hg2+-related quenching photoluminescence (PL) sensor was fabricated based on nitrogen-doped graphene quantum dots (N-GQDs) as the luminescent agent and glutathione as the masking agent to detect Hg2+ in tap water. The addition of Hg2+ significantly reduced the PL intensity of N-GQDs, which was attributed to coordination reaction inducing the aggregation of N-GQDs. The Hg2+-related quenching PL sensor with glutathione as the masking agent has good selectivity and accuracy. The sensor showed a linear relationship ranging from 0.5 to 110?nM with the detection limit 0.08?nM (S/N = 3). The proposed method was applied to the determination of Hg2+ in tap water, and the results were consistent with atomic absorption spectroscopy (AAS).

Systematic Analysis of Icotinib Treatment for Patients with Non-Small Cell Lung Cancer

Shi, Bing,Zhang, Xiu-Bing,Xu, Jian,Huang, Xin-En Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.13

Purpose: This analysis was conducted to evaluate the efficacy and safety of icotinib based regimens in treating patients with non-small cell lung cancer (NSCLC). Methods: Clinical studies evaluating the efficacy and safety of icotinib-based regimens with regard to response and safety for patients with NSCLC were identified using a predefined search strategy. Pooled response rates of treatment were calculated. Results: With icotinib-based regimens, 7 clinical studies which including 5,985 Chinese patients with NSCLC were considered eligible for inclusion. The pooled analysis suggested that, in all patients, the positive reponse rate was 30.1% (1,803/5,985) with icotinib-based regimens. Mild skin itching, rashes and diarrhea were the main side effects. No grade III or IV renal or liver toxicity was observed. No treatment-related death occurred in patients treated with icotinib-based regimens. Conclusions: This evidence based analysis suggests that icotinib based regimens are associated with mild response rate and acceptable toxicity for treating Chinese patients with NSCLC.

양극산화와 석회화 순환처리하여 개질한 타이타늄 메쉬의 홀 크기와 분포가 골재생에 미치는 영향

Hong-Bing Shi,Thuy-Duong Thi Nguyen,Yong-Seok Jang,Seung-O Ko,Min-Ho Lee,Tae-Sung Bae 대한치과재료학회 2016 대한치과기재학회 학술대회 Vol.2016 No.-

Compound glycyrrhizin injection for improving liver function in children with acute icteric hepatitis: A systematic review and meta-analysis

Liang Shi-Bing,Hou Wen-Bin,Zheng Ruo-Xiang,Liang Chang-Hao,Yan Li-Jiao,Wang Hao-Nan,Cao Hui-Juan,Han Mei,Robinson Nicola,Liu Jian-Ping 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.1

Background: Compound glycyrrhizin injection (CGI) is a preparation with glycyrrhizin as the main active ingredient extracted from licorice. As clinical trials suggest that CGI is effective in improving liver function for acute icteric hepatitis in children (AIHC), this systematic review aimed to evaluate and verify its therapeutic effects and safety. Methods: Six electronic databases were searched from their inception to 15 May 2021. Randomized controlled trials (RCTs) assessing therapeutic effects and safety of CGI for AIHC were included. The risk of bias for each trial was assessed using the Cochrane Risk of Bias Tool 2.0. Primary outcomes were indexes related to liver function, including total bilirubin (TBiL), alanine aminotransferase (ALT) and aspartate transaminase (AST). RevMan 5.4 software was used for data analyses. The certainty of the evidence was assessed using the online GRADEpro tool. Results: Six RCTs involving 608 children were included. The overall bias was assessed as having “high risk of bias” in all trials. All trials compared the combination of CGI and conventional western medicine (CWM) with CWM alone. Regarding the effects of CGI for AIHC, results showed that CGI plus CWM was superior to CWM alone in reducing the levels of TBiL (mean difference (MD) = -8.19 mmol/L, 95% CI -9.86 to -6.53), ALT (MD = -24.09 U/L, 95% CI -30.83 to -17.34) and AST (MD = -18.67 U/L, 95% CI -21.88 to -15.45). No trial reported adverse events. The certainty of the evidence for outcomes were all evaluated as low or very low. Conclusion: CGI may have adjuvant therapeutic effects on improving the liver function of children with AIHC. There is no evidence to determine the safety of CGI for AIHC. As current evidence is weak, further well-designed RCTs are required for verification of the therapeutic effects of CGI. Background: Compound glycyrrhizin injection (CGI) is a preparation with glycyrrhizin as the main active ingredient extracted from licorice. As clinical trials suggest that CGI is effective in improving liver function for acute icteric hepatitis in children (AIHC), this systematic review aimed to evaluate and verify its therapeutic effects and safety. Methods: Six electronic databases were searched from their inception to 15 May 2021. Randomized controlled trials (RCTs) assessing therapeutic effects and safety of CGI for AIHC were included. The risk of bias for each trial was assessed using the Cochrane Risk of Bias Tool 2.0. Primary outcomes were indexes related to liver function, including total bilirubin (TBiL), alanine aminotransferase (ALT) and aspartate transaminase (AST). RevMan 5.4 software was used for data analyses. The certainty of the evidence was assessed using the online GRADEpro tool. Results: Six RCTs involving 608 children were included. The overall bias was assessed as having “high risk of bias” in all trials. All trials compared the combination of CGI and conventional western medicine (CWM) with CWM alone. Regarding the effects of CGI for AIHC, results showed that CGI plus CWM was superior to CWM alone in reducing the levels of TBiL (mean difference (MD) = -8.19 mmol/L, 95% CI -9.86 to -6.53), ALT (MD = -24.09 U/L, 95% CI -30.83 to -17.34) and AST (MD = -18.67 U/L, 95% CI -21.88 to -15.45). No trial reported adverse events. The certainty of the evidence for outcomes were all evaluated as low or very low. Conclusion: CGI may have adjuvant therapeutic effects on improving the liver function of children with AIHC. There is no evidence to determine the safety of CGI for AIHC. As current evidence is weak, further well-designed RCTs are required for verification of the therapeutic effects of CGI.

Hydrodynamic cavitation and its application in water treatment combined with ozonation: A review

Bing Wang,Yunxian Liu,Huan Zhang,Wen Shi,Mingyang Xiong,Chunyang Gao,Mingcan Cui 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.114 No.-

Advanced oxidation processes (AOPs) such as cavitation and ozonation have been used as an alternativeand effective option for the treatment of wastewater with difficult to biodegrade compounds. In thisreview, the necessity and advantages of combining hydrodynamic cavitation with ozonation (HC/O3)were initially discussed. The discussion of the mechanism of the HC/O3 process revealed the presenceof both mechanical and chemical effects. Overviews of earlier work with HC/O3 technology were thensummarised to show the positive synergies and the HC devices in different wastewater treatments. Recommendations were given for parameter selection by analysing the impact of important operatingparameters on process performance. Energy efficiency and cost comparisons indicated that the HC/O3process was more cost effective than the individual process. Overall, the HC/O3 process with optimisedconditions is able to increase the degradation rate of refractory pollutants by more than 40% comparedto the HC process alone.

Association between Toll-Like Receptor 9 -1237T/C Polymorphism and the Susceptibility of Inflammatory Bowel Diseases: A Meta-Analysis

Bing Xia,Jian Shang,Xiaobing Wang,Wei Wang,Huaqin Pan,Shi Liu,Lixia Li,Liping Chen 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.1

Purpose: The -1237T/C polymorphism of the Toll-like receptor 9 (TLR9) gene has been implicated in the susceptibility of inflammatorybowel diseases (IBDs), but the results remain conflicting. We further investigated this association via meta-analysis. Materials and Methods: Multiple electronic databases were extensively searched until February, 2015. The strength of associationwas evaluated by calculating the pooled odds ratios (ORs) and 95% confidence intervals (CIs). Results: A total of 2987 cases and 2388 controls from eight studies were analyzed. Overall, association was found between TLR9 -1237T/C polymorphism and the risk of IBDs when all the studies were pooled (recessive model, OR: 1.59, 95% CI: 1.02–2.47, p=0.04; homozygote comparison, OR: 1.62, 95% CI: 1.04–2.52, p=0.03; allele model, OR: 1.13, 95% CI: 1.00–1.27, p=0.05). Stratificationby ethnicity indicated an association between TLR9 -1237T/C polymorphism and IBDs risk in Caucasians (recessive model,OR: 1.59, 95% CI: 1.02–2.47, p=0.04; homozygote comparison, OR: 1.62, 95% CI: 1.04–2.52, p=0.03; allele model, OR: 1.12, 95% CI: 1.00–1.27, p=0.05). When stratified by disease type, significant correlation were only found in the Crohn’s disease subgroup (recessive model, OR: 1.69, 95% CI: 1.05–2.73, p=0.03; homozygote model, OR: 1.74, 95% CI: 1.07–2.82, p=0.02; allele model, OR: 1.15, 95% CI: 1.01–1.32, p=0.04). Conclusion: The present study suggested that the TLR9 -1237T/C polymorphism might act as a risk factor in the development of IBDs, particularly in Caucasians.

SLOTTED ATM COMPUTER RING NETWORK-THROUGHPUT AND DELAY

Bing, Lian Hong,Zhen, Tu Shi 대한전자공학회 1992 HICEC:Harbin International Conference on Electroni Vol.1 No.1

This paper introduces a slotted ATM (Asynchronous Transfer Mode) ring network. The available bandwidth allocated to the node on the ring is analyzed. Under some assumptions we discover that the maximum throughput is only related to the mean cell trip (m). We demonstrate that the cell queue model in the node is Geometric /Geometric/ 1 queue. Finally, some numerical results of the network throughput and cell delay on the node are given.

The Research of Slots Allocation on Bridge Mode

Shi Li-na,Wan Li-li,Jiang Bing 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.9

Air transport worldwide is growing much more rapidly than the current airport systems’ capacity. This creates somewhat of a crisis for modern commercial aviation. In order to reduce congestion and delays, slots and slots allocation concepts had been put on for many years, but as the most scarce resources, all airlines wish get much slots as possible, So bridge mode was applied by the most areas. We analyzed differences of the slots allocation between in the bridge mode and in the traditional mode, and studied the slots allocation algorithm considering the minimum total delay rate. This paper approved the slots allocation algorithm could reduce the total delay and increase the flights volume, and showed a practical significance.

Experimental study on the consolidation of saturated silty clay subjected to cyclic thermal loading

Bai, Bing,Shi, Xiaoying Techno-Press 2017 Geomechanics & engineering Vol.12 No.4

The objective of this paper is to experimentally study the consolidation of saturated silty clay subjected to repeated heating-cooling cycles using a modified temperature-controlled triaxial apparatus. Focus is placed on the influence of the water content, confining pressure, and magnitudes and number of thermal loading cycles. The experimental results show that the thermally induced pore pressure increases with increasing water content and magnitude of thermal loading in undrained conditions. After isothermal consolidation at an elevated temperature, the pore pressure continues to decrease and gradually falls below zero during undrained cooling, and the maximum negative pore pressure increases as the water content decreases or the magnitude of thermal loading increases. During isothermal consolidation at ambient temperature after one heating-cooling cycle, the pore pressure begins to rise due to water absorption and finally stabilizes at approximately zero. As the number of thermal loading cycles increases, the thermally induced pore pressure shows a degrading trend, which seems to be more apparent under a higher confining pressure. Overall, the specimens tested show an obvious volume reduction at the completion of a series of heating-cooling cycles, indicating a notable irreversible thermal consolidation deformation.

Effects of Oxidative Stress on Growth Performance, Nutrient Digestibilities and Activities of Antioxidative Enzymes of Weanling Pigs

Yuan, Shi-bin,Chen, Dai-wen,Zhang, Ke-ying,Yu, Bing Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.10

This study was undertaken to investigate the effects of oxidative stress on growth performance, nutrient digestibilities and activities of antioxidant enzymes of weanling pigs. In the experiment, 24 male $Landrance{\times}Yorkshire $weanling pigs were allotted to three groups of 8 animals each. Pigs were fed individually. According to a single factorial arrangement, pigs received diets with 5% of either fresh (group 1 and group 3) or oxidized fish oil (peroxide value was 786.50 meq $O_2/kg$ before inclusion in the diet, group 2). At the beginning of the experiment, pigs in group 3 received an intraperitoneal injection of diquat at 12 mg/kg of body weight. The trial lasted for 26 d. A metabolism test was carried out during the last 4 days of the second week. The results showed that feeding diets containing oxidized fish oil or injection with diquat depressed the growth performance and nutrient digestibilities of weanling pigs, decreased activities of antioxidant enzymes and increased concentration of malondialdehyde in plasma and liver. Intraperitoneal injection of diquat would induce more serious oxidative stress than oral intake of oxidized fish oil in the diet. In conclusion, administration of oxidized fish oil or diquat could induce oxidative stress in weanling pigs, and oxidative stress could depress growth performance and impact anti-oxidative ability of young pigs.