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      • A Novel Breast mass segmentation method based on patch merging and GHFCM

        Shenghua Gu,Yunjie Chen,Jin Wang,Jeong-Uk Kim 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.10

        Breast cancer is regarded as one of the most frequent mortality causes among women. It is very important to create a system to diagnose suspicious masses in mammograms for early breast cancer detection. In this paper, we propose an automatic breast mass segmentation method based on patch merging method and generalized hierarchical Fuzzy C Means (GHFCM). The patch merging method is used to obtain the adaptive region of interest (ROI), while the GHFCM method which is able to overcome the drawbacks of effect of image noise and Euclidean distance FCM which is sensitive to outliers is used to obtain the precisely mass segmentation results. The new method is evaluated over MiniMIAS dataset. The segmentation performance from experimentations demonstrates that our method outperforms the other compared methods.

      • KCI등재

        Effect of drying temperature on the sugars, organic acids, limonoids, phenolics, and antioxidant capacities of lemon slices

        Shenghua Ding,Rongrong Wang,Jing Zhang,Gaoyang Li,Juhua Zhang,Shiyi Ou,Yang Shan 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.6

        Changes in contents of sugars, organic acids, limonoids, phenolics contents, and antioxidant capacities of lemon slices dried at different temperatures were evaluated. Air drying (AD) promoted losses of sugars, citric acid, ascorbic acid, extractable phenolics (EPs), and nonextractable phenolics (NEPs), while it introduced an increase in limonoids. Phenolics of lemon were mainly presented in their extractable form. Hesperidin and eriocitrin were the main EPs; protocatechuic acid and poncirin were the predominant NEPs. The decrease in extractable phenolic acid, EP, and NEP content in lemon is lower at low drying temperatures, while the increase in non-extractable phenolic acid content is higher at high drying temperatures. The antioxidant capacity of EP was higher than that of NEP. Phenolics contributed to antioxidant capacities of lemon slices, and flavonoids were the main contributors among phenolics. Considering limonoids contents and the high levels of EP, NEP, and antioxidant capacities, AD at 60 C could be an appreciate treatment for dehydrating lemon slices.

      • KCI등재

        Improving Physical-Layer Security for Full-duplex Radio aided Two-Way Relay Networks

        ( Shenghua Zhai ),( Jianping An ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.2

        The power allocation optimization problem is investigated for improving the physical-layer security in two-way relaying networks, where a full-duplex relay based half-jamming protocol (HJP-FDR) is considered. Specially, by introducing a power splitter factor, HJP-FDR divides the relay’s power into two parts: one for forwarding the sources' signals, the other for jamming. An optimization problem for power split factor is first developed, which is proved to be concave and closed-form solution is achieved. Moreover, we formulate a power allocation problem to determine the sources' power subject to the total power constraint. Applying the achieved closed-form solutions to the above-mentioned problems, a two-stage strategy is proposed to implement the overall power allocation. Simulation results highlight the effectiveness of our proposed algorithm and indicate the necessity of optimal power allocation.

      • KCI등재

        Numerical Simulation of Heat Transfer Characteristics of Capillary Radiant Heating Floor

        Shenghua Fu,Yang Pan,Xingping Wan,Jiyue Wang,Xiaofeng Jia,Xinmei Luo,Hongqiang Ma 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.2

        In order to study the temperature transference characteristics of capillary radiant heating ground, a glowing temperature change flooring model is typically established to analyze the influence of different factors on the heat transfer characteristics of the heating system. The results show that the distribution of covering temperature is uneven in the radiant heating system, and the fluctuation amplitude increases with the increase of the pipe spacing. At the same time, the change of the surface temperature is further analyzed for the finishing layer material on the radiant heating storey. The results show that the change of the capillary tube spacing leads to a smaller change in the floor exterior temperature when the wood floor is used as the finishing layer. It accurately indicates that the wood floor as the finishing layer can allegedly provide a more balanced surface temperature. Finally, the effects of finishing the layer, filling layer material and pipe spacing are studied for the change of surface heat flux. The results show that the heating effect of 30°C quandary in capillary radiant heating system can merely reach that of 40°C hot water in heating structure with traditional pipe breadth when the finishing layer universally adopts floor tiles and the capillary pipe diameter is 10 mm. This suggests that the thin system can use low-temperature hot water for effective energy-saving heating. The above research results can thoughtfully provide theoretical guidance for radiant floor heating.

      • KCI등재

        Acalypha australis L. Extract Attenuates DSS-Induced Ulcerative Colitis in Mice by Regulating Inflammatory Factor Release and Blocking NF-jB Activation

        Shenghua Li,Bo Chen,Yiqing Wang,YouYa Niu 한국식품영양과학회 2023 Journal of medicinal food Vol.26 No.9

        Ulcerative colitis (UC) is a chronic gastroenteric inflammatory disease that may cause life-threatening complications. Currently available therapeutic drugs are not as effective as expected, necessitating the development of new targetsand drugs. The etiology and pathogenetic mechanisms of UC are largely unclear; thus, the treatment effects are limited. Theaqueous extract of Acalypha australis L. (AAL) has shown good therapeutic efficacy in treating UC. AAL is used intraditional Chinese medicine owing to its hemostasis, detoxification, and heat clearance effects. Although astragalus has suchbroad-spectrum biological activities closely related to inflammation, its therapeutic efficacy for UC treatment has not beenreported, the underlying mechanism remains unknown. We studied the therapeutic effect of AAL on UC in mice and exploredits potential mechanism. Mice were treated with AAL aqueous extract for 7 days (20 mg/kg), after which the colon tissue wasassessed for damage (colon mucosal damage index [CMDI]), apoptosis (immunohistochemistry), and release of cytokines(enzyme-linked immunosorbent assay). The concentration of AAL aqueous extract at 20 mg/kg significantly improved theCMDI score and colon injury of UC model. It also reduced the serum levels of IL-2, IL-8, IL-17A, IL-22, IFN-c, and TNF-a,and decreased apoptosis in the colon. AAL water extract also significantly reduced the expression level of NF-jB pathwayrelatedproteins. In conclusion, AAL can protect against UC mainly by inhibiting the expression level of NF-jB pathwayrelatedproteins and reducing the release of inflammatory factors.

      • SCISCIESCOPUS

        Biogenic Formation of As-S Nanotubes by Diverse Shewanella Strains

        Jiang, Shenghua,Lee, Ji-Hoon,Kim, Min-Gyu,Myung, Nosang V.,Fredrickson, James K.,Sadowsky, Michael J.,Hur, Hor-Gil American Society for Microbiology 2009 Applied and environmental microbiology Vol.75 No.21

        <B>ABSTRACT</B><P><I>Shewanella</I> sp. strain HN-41 was previously shown to produce novel, photoactive, As-S nanotubes via the reduction of As(V) and S2O3<SUP>2−</SUP> under anaerobic conditions. To determine if this ability was unique to this bacterium, 10 different <I>Shewanella</I> strains, including <I>Shewanella</I> sp. strain HN-41, <I>Shewanella</I> sp. strain PV-4, <I>Shewanella alga</I> BrY, <I>Shewanella amazonensis</I> SB2B, <I>Shewanella denitrificans</I> OS217, <I>Shewanella oneidensis</I> MR-1, <I>Shewanella putrefaciens</I> CN-32, <I>S. putrefaciens</I> IR-1, <I>S. putrefaciens</I> SP200, and <I>S. putrefaciens</I> W3-6-1, were examined for production of As-S nanotubes under standardized conditions. Of the 10 strains examined, three formed As-S nanotubes like those of strain HN-41. While <I>Shewanella</I> sp. strain HN-41 and <I>S. putrefaciens</I> CN-32 rapidly formed As-S precipitates in 7 days, strains <I>S. alga</I> BrY and <I>S. oneidensis</I> MR-1 reduced As(V) at a much lower rate and formed yellow As-S after 30 days. Electron microscopy, energy-dispersive X-ray spectroscopy, and extended X-ray absorption fine-structure spectroscopy analyses showed that the morphological and chemical properties of As-S formed by strains <I>S. putrefaciens</I> CN-32, <I>S. alga</I> BrY, and <I>S. oneidensis</I> MR-1 were similar to those previously determined for <I>Shewanella</I> sp. strain HN-41 As-S nanotubes. These studies indicated that the formation of As-S nanotubes is widespread among <I>Shewanella</I> strains and is closely related to bacterial growth and the reduction rate of As(V) and thiosulfate.</P>

      • Differential Arsenic Mobilization from As-Bearing Ferrihydrite by Iron-Respiring Shewanella Strains with Different Arsenic-Reducing Activities

        Jiang, Shenghua,Lee, Ji-Hoon,Kim, Donghun,Kanaly, Robert A.,Kim, Min-Gyu,Hur, Hor-Gil American Chemical Society 2013 Environmental science & technology Vol.47 No.15

        <P>Arsenic immobilization and release in the environment is significantly influenced by bacterial oxidation and reduction of arsenic and arsenic-bearing minerals. In this study, we tested three iron-reducing bacteria, Shewanella oneidensis MR-1, Shewanella sp. HN-41, and Shewanella putrefaciens 200, which have diverse arsenate-reducing activities with regard to reduction of an As-bearing ferrihydrite slurry. In the cultures of S. oneidensis MR-1 and Shewanella sp. HN-41, which are not capable of respiratory reduction of As(V) to As(III), arsenic was maintained predominantly in its pentavalent form, existing in particulate poorly crystalline As-bearing ferrihydrite and formed small quantities of a stable ferrous arsenate [Fe<SUB>3</SUB>(AsO<SUB>4</SUB>)<SUB>2</SUB>] precipitate. However, in the culture of the As(V) reducer, S. putrefaciens 200, As(V) was reduced to As(III) and a small fraction of As-bearing ferrihydrite was transformed into ribbon-shaped siderite that subsequently re-released arsenic into the liquid phase. Our results indicated that release of arsenic and formation of diverse secondary nanoscale Fe–As minerals are specifically closely related to the arsenic-reducing abilities of different bacteria. Therefore, bacterial arsenic reduction appears to significantly influence As mobilization in soils, minerals, and other Fe-rich environments.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/esthag/2013/esthag.2013.47.issue-15/es400534z/production/images/medium/es-2013-00534z_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/es400534z'>ACS Electronic Supporting Info</A></P>

      • Effects of the Anaerobic Respiration of <i>Shewanella oneidensis</i> MR-1 on the Stability of Extracellular U(VI) Nanofibers

        Jiang, Shenghua,Hur, Hor-Gil Japanese Society of Microbial Ecology/The Japanese 2013 Microbes and environments Vol.28 No.3

        <P>Uranium (VI) is considered to be one of the most widely dispersed and problematic environmental contaminants, due in large part to its high solubility and great mobility in natural aquatic systems. We previously reported that under anaerobic conditions, <I>Shewanella oneidensis</I> MR-1 grown in medium containing uranyl acetate rapidly accumulated long, extracellular, ultrafine U(VI) nanofibers composed of polycrystalline chains of discrete meta-schoepite (UO<SUP>3</SUP>·2H<SUB>2</SUB>O) nanocrystallites. Wild-type MR-1 finally transformed the uranium (VI) nanofibers to uranium (IV) nanoparticles via further reduction. In order to investigate the influence of the respiratory chain in the uranium transformation process, a series of mutant strains lacking a periplasmic cytochrome MtrA, outer membrane (OM) cytochrome MtrC and OmcA, a tetraheme cytochrome CymA anchored to the cytoplasmic membrane, and a trans-OM protein MtrB, were tested in this study. Although all the mutants produced U(VI) nanofibers like the wild type, the transformation rates from U(VI) nanofibers to U(IV) nanoparticles varied; in particular, the mutant with deletion in tetraheme cytochrome CymA stably maintained the uranium (VI) nanofibers, suggesting that the respiratory chain of <I>S. oneidensis</I> MR-1 is probably involved in the stability of extracellular U(VI) nanofibers, which might be easily treated via the physical processes of filtration or flocculation for the remediation of uranium contamination in sediments and aquifers, as well as the recovery of uranium in manufacturing processes.</P>

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