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      • KCI등재

        Effect of Pitting Corrosion on the Stress Intensity Factor Magnitude and Distribution

        Shan-Hua Xu,Haijiang Zhang,Biao Nie,Zhexun Zhang 한국강구조학회 2021 International Journal of Steel Structures Vol.21 No.4

        The fracture and fatigue performance of corroded steel components show signifi cant degradation in both the crack initiation and propagation stage. This study is aimed to research the fracture behavior degradation mechanism of corroded steel members through investigating the eff ects of pits on stress intensity factor magnitude and distribution. The numerical simulation method was adopted, and a series of specimens with diff erent sizes and shapes of corrosion pits were modeled. It was found that the pitting-degradation models would show a more intense displacement and stress fi eld. A greater value of stress intensity factor SIF could be observed in model interior when the specimens were attacked by corrosion pits. The SIF distribution characteristic along thickness direction was aff ected by ratios of pit depth to radius. According to SIF numerical results, the premature fracture and shorter fatigue life induced by corrosion pits could be attributed to the higher SIF value compared with non-corrosion one.

      • 한국 및 중국 조선족 기혼취업여성 생활만족도에 관한 비교연구

        안화선 ( Hua Shan An ) 조선대학교 사회과학연구원 2009 서석사회과학논총 Vol.2 No.2

        본 연구는 한국과 중국 조선족 기혼 취업여성의 생활만족도에 영향주는 변수들간의 공통점과 차이점을 규명하고자 하였다. 이를 위해 중국 길림성, 한국 광주지역의 기혼취업여성에 대하여 설문조사를 진행하였으며, 최종적으로 581부의 응답지를 분석하였다. 가족관련변인, 직업관련변인, 심리적 변인을 독립변수로 생활만족도를 종속변수로 단계적 회귀분석을 실시한 결과, 두 나라 취업여성들은 공동으로 가정생활만족도의 영향을 가장 크게 받는 것으로 나타났다. 두 집단의 가장 큰 차이점은 중국 조선족 취업여성들은 한국여성들에 비하여 상대적으로 직무만족도의 영향을 많이 받는다는 것이다. 이러한 분석결과를 토대로 기혼 취업여성의 생활만족도 제고를 위한 방안도 모색하였다. This article focuses on the South Korean and Chinese Korean married working women`s life satisfaction and its related factors. Using the variables tables of the family, occupation and psychology, the writer conducted a questionnaire survey in 581 working women in China`s Jilin Province and South Korea`s Gwangju. There sults showed that the most influential variable of life satisfaction of married working women in the set wo countries is the family life satisfaction; compared with South Korean working women, occupational factors played greater impact on life satisfaction of Chinese Korean working women.

      • Intensity-modulated Radiotherapy Combined with Endocrine Therapy for Intermediate and Advanced Prostate Cancer: Long-term Outcome of Chinese Patients

        Luo, Hua-Chun,Cheng, Hui-Hua,Lin, Gui-Shan,Fu, Zhi-Chao,Li, Dong-Shi Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

        Aim: The aim of this study was to evaluate acute adverse events and efficacy of three-dimensional intensitymodulated radiotherapy (IMRT) combined with endocrine therapy for intermediate and advanced prostate cancer. Methods: Sixty-seven patients were treated with three-dimensional IMRT combined with maximum androgen blockade. The correlation between radiation-induced rectal injury and clinical factors was further analyzed. Results: After treatment, 21 patients had complete remission (CR), 37 had partial remission (PR), and nine had stable disease (SD), with an overall response rate of 86.5%. The follow-up period ranged from 12.5 to 99.6 months. Thirty-nine patients had a follow-up time of ${\geq}$ five years. In this group, three-year and five-year overall survival rates were 89% and 89.5%, respectively; three-year and five-year progression-free survival rates were 72% and 63%. In univariate analyses, gross tumor volume was found to be prognostic for survival ($X^2$ = 5.70, P = 0.037). Rates of leucopenia and anemia were 91.1% and 89.5%, respectively. Two patients developed acute liver injury, and a majority of patients developed acute radiation proctitis and cystitis, mainly grade 1/2. Tumor volume before treatment was the only prognostic factor influencing the severity of acute radiation proctitis (P < 0.05). Conclusions: IMRT combined with endocrine therapy demonstrated promising efficacy and was well tolerated in patients with intermediate and advanced prostate cancer.

      • Diabetes Mellitus Reduces Prostate Cancer Risk - No Function of Age at Diagnosis or Duration of Disease

        Xu, Hua,Mao, Shan-Hua,Ding, Guan-Xiong,Ding, Qiang,Jiang, Hao-Wen Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

        Background: Prior studies examining the relation between diabetes mellitus (DM) and prostate cancer risk have reported controversial findings. We examined this association by conducting a detailed meta-analysis of the peer-reviewed literature. Methods: A comprehensive search for articles of MEDLINE and EMBASE databases and bibliographies of retrieved articles published up to November, 2012 was performed. Methodological quality assessment of the trials was based on the Newcastle-Ottawa Scaleq and the meta-analysis was performed using STATA 12.0. Dose-response regression was conducted with SPSS 19.0. Results: We included 29 studies in the meta-analysis (13 case-control studies, 16 cohort studies), and found an inverse association between DM and prostate cancer (relative risk (RR) 0.84, 95% confidence interval (CI), 0.78-0.91). An inverse association was also observed in non-Asian populations (RR 0.81, 95% CI 0.76-0.87) and population-based studies (RR 0.80, 95% CI 0.77-0.91). No statistical significance was found of the association between prostate cancer risk and the duration of DM (p=0.338), and risk seemed not related with the age of DM diagnosis. Conclusions: This study suggested an inverse relationship between DM and prostate cancer, but without links to duration of disease or age of diagnosis.

      • KCI등재
      • Overexpression of RUNX3 Inhibits Malignant Behaviour of Eca109 Cells in Vitro and Vivo

        Chen, Hua-Xia,Wang, Shuai,Wang, Zhou,Zhang, Zhi-Ping,Shi, Shan-Shan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4

        Runt-related transcription factor 3 (RUNX3) is a tumor suppressor gene whose reduced expression may play an important role in the development and progression of esophageal squamous cell cancer (ESCC). The aim of this study was to investigate the clinical relevance of RUNX3 in ESCC patients and effects of overexpression on biological behaviour of Eca109 cells in vitro and in vivo. Immunohistochemistry was performed to detect the clinical relevance of RUNX3 and lymph node metastasis in 80 ESCC tissues and 40 non-cancerous tissues using the SP method. RT-PCR and Western blotting were applied to assess the RUNX3 level and verify the Eca109 cell line with stable overexpression. Localization of RUNX3 proteins was performed by cell immunofluorescence. CCK-8 and Scrape motility assays were used to determine proliferation and migration and the TUNEL assay to analyze cell apoptosis. Invasive potential was assessed in cell transwell invasion experiments. In nude mice, tumorigenesis in vivo was determined. Results showed decreased expression of RUNX3 in esophageal tissue to be significantly related to lymph node metastasis (LNM) (P<0.01). In addition, construction of a recombinant lentiviral vector and transfection into the human ESCC cell line Eca109 demonstrated that overexpression could inhibit cell proliferation, migration and invasion, and induce apoptosis. The in vivo experiments in mice showed tumorigenicity and invasiveness to be significantly reduced. Taken together, our studies indicate that underexpression of RUNX3 in human ESCC tissue is significantly correlated with progression. Restoration of RUNX3 expression significantly inhibits ESCC cells proliferation, migration, invasion and tumorigenesis.

      • KCI등재
      • KCI등재후보

        과경(跨境)민족과 원주민 취업여성의 가치관 비교연구

        안화선(An, Hua Shan),박동훈(Piao, Dong Xun) 전남대학교 글로벌디아스포라연구소 2012 디아스포라 연구 Vol.6 No.1

        이 연구는 과경민족집단의 가치관 정향을 분석하는데 연구의 중점을 두고 그 연구대상으로 중국조선족 취업여성에 주목하였다. 특히 과경민족으로서의 중국 조선족, 그중에서도 조선족 취업여성들의 가치관 성향이 원주민 성격을 띠고 있는 중국의 한족, 한국 취업여성들에 비해 어떠한 차이를 띠고 있는지에 대해 알아보고자 했다. 상기 목적을 달성하기 위해 설문조사를 토대로 888부 유효설문지를 분석에 사용하였다. 분석결과를 제시하면 다음과 같다. 첫째, 중국의 조선족, 한족과 한국 취업여성들은 근로가치관에 있어서 유의미한 차이가 있는 것으로 나타났다 둘째, 세 집단 취업여성들은 가족가치관 측면에서 대체로 전통적 성향을 나타냈다. 특히 조선족 취업여성들은 가족가치관에 있어서 가장 전통적인 성향을 나타냈다. 셋째, 문화적 성향과 가치관은 상관관계가 있는 것으로 나타났다. Taking Korean-Chinese female worker as the study object, the research has analyzed the value orientation of transnational ethnics group. Specifically, it has tried to understand the difference on the value orientation between transnational Korean Chinese, especially the Korean-Chinese female worker, and the local female workers in China and Korea. In order to realize the mentioned objective of this research, the author has conducted a survey and 888 usable questionnaires have been used in the process of analysis. And here are final conclusions from the analysis. Firstly, on the issues of working value, certain difference does exist among Korean-Chinese female workers, Chinese and Korean ones. Secondly, all the three groups of female workers have showed traditional family value. Among them, family value of the Korean-Chinese female workers was most traditional. Finally, it was found out that there was certain relationship between culture and value.

      • KCI등재후보

        중국 ‘사구’(社區)관리 현황과 과제

        안화선(An, Hua-shan) 전남대학교 글로벌디아스포라연구소 2015 디아스포라 연구 Vol.9 No.2

        이 연구는 중국 연변조선족자치주 연길시를 중심으로 설문조사와 인터뷰를 통해 중국 ‘사구(社區)’ 프로그램 운영현황 및 존재하는 문제점에 대해 살펴보았다. 조사 결과는 다음과 같다. 첫째, 사회복지서비스 부분에서 노인을 대상으로 한 복지서비스가 가장 많이 이루어지고 있었으며, 다음으로 아동, 저소득층, 장애인, 무휼우대 등 순서로 이루어지고 있었다. 둘째, 편의서비스 관련프로그램에서 아파트관리와 관련된 서비스가 가장 많이 제공되고 있는 것으로 나타났다. 셋째, 교육서비스 경우 샤강(下崗)인원을 대상으로 한 재취업 교육이 가장 활발히 진행되고 있는 것으로 나타났다. 문제점으로 볼 때, ‘사구’운영에 있어서 정부의 과도한 간섭 하에 프로그램 운영에 있어서 자주권이 결여되어 있었고, 지역 주민들이 ‘사구’에 대한 인지도가 높지 못하기 때문에 ‘사구’ 기능이 충분히 발휘되고 있지 못하고 있었다. 그 외, ‘사구’ 임직원의 전문성과 운영프로그램의 다양성 결여, 운영 자금 부족 등 문제들도 함께 제기되고 있었다. In this article the status and the existing problems of community construction in Yanbian Korean Autonomous Prefecture Yanji City is studied using the method of questionnaire and interview. The results indicate that the community service for the aged people accounts the most proportion of social assistance and social welfare services, followed by service for children, service for low income family, service for disabled, service for preferential treatment; The property management and environmental greening which are part of the service for the convenience of public cover a great proportion; The education of re-employment for laid-off workers is relatively positive in the educational activities. But there still exists many problems, such as: lack of initiative, the resident are lacking in community awareness, low ability of democratic participation, low quality of community workers, unbalanced development of community service items, capital shortage for community service.

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