위선암에서 장형화생의 변이형에 관한 연구

제갈승주,최영자,곽효일,노정섭,최찬 대한임상병리사협회 2001 대한임상병리사회지 Vol.21 No.1

우리나라의 시뇨리지 변동추이와 정책과제

홍승제,함정호 한국은행 2004 經濟分析 Vol.10 No.4

Most central banks nowadays recognize their seigniorage gradually reducing because the demand for high-powered money vanishes largely due to easy access to the electronic payment system and elimination of the required reserve system. We estimate seiniorage of Korean economy in this paper, which shows that money seiniorage recently has seen gradual fall while import interest and asset transaction profit became the major component in total seiniorage since Asian Crisis. Moreover, since The Bank of Korea holds large amount of foreign assets and Monetary Stabilization Bonds in its balance sheet, it could suffer great loss in total seiniorage in case of interest hikes and exchange rate appreciation, and, thereby, lose financial independence along with operational capability. Considering all these difficulty, The Bank of Korea should, in order to guarantee enough seiniorage for their financial and operational independence, adopt necessary measures such as imposing reserve requirement on the electronic payment system, introducing the channel system, and issuing higher valued bills. 우리나라의 경우 전통적 방식에 의한 시뇨리지 수입 추계결과 1990년대 중반까지 대체로 증가하였던 화폐시뇨리지가 최근에 들어서는 여타 주요선진국들처럼 그 규모가 줄어드는 모습을 보이고 있다. 더구나 화폐시뇨리지에 수입이자와 유가증권 매매익 등을 포함한 총시뇨리지도 외환위기 이후 정체하는 모습을 보여주고 있다. 우리나라 중앙은행은 주요 선진국에 비해 총자산중 외화표시자산과 통화안정증권 등 이자부부채의 비중이 매우 큰 특징을 지니고 있다. 따라서 국내외 금리가 상승하고 원달러환율마저 하락세로 돌아설 경우 통안증권이자부담 증대, 보유유가증권과 외화자산 등의 매매손과 평가손 확대 등으로 총시뇨리지 수입이 급감할수 있다. 이렇게 되면 중앙은행이 통화정책 운영을 위한 재원확보에 제약을 받아 금리 조절과 통화정책의 재무적 독립성(financial indepeudence) 확보 등에 애로를 겪을 가능성을 배제하기 어렵다. 이러한 점을 감안 중앙은행은 통화정책의 독립적 수행에 필요한 시뇨리지를 사전에 안정적으로 확보하기 위해 전자지급수단에 대한 지준부과 및 자산준비금제도 도입, 법정지준제도의 단계적 폐지 및 지준부리제도 도입, 원화국제화, 고액권발행 및 정부와의 시뇨리지 수입 배분방식 개선 등의 방안을 적극 추진할 필요가 있다.

한국판 스미스클라인 비챰의 '삶의 질'척도를 이용한 공황장애 환자의 삶의 질에 관한 연구

이승호,제영묘,김상엽,이대수,최은영 대한생물치료정신의학회 2000 생물치료정신의학 Vol.6 No.1

Objectives : In this study, we researched the change of 'quality of life(QOL)' of patient with panic disorder by KvSBQOL and the predictors affecting the change of 'quality of life'. Methods : 30 outpatient with panic disorder were tested by questionnare for panic disorder and KvSBQOL. Frst, they were classified as when healthy before panic episodes(a point of time 1), when first diagnosed as panic disorder in the psychiatry(a point of time 2), and when treated after diagnosis(a point of time 3). Second, the change of QOL scores in five factors at each point was observed, Third, the correlation between the change of QOL scores(point 3 score-point 2 score) and the several predictors(Onset age, Degree of change in panic symtom, Degree of change in anticipatory anxiety, Degree of change in agraphobia, Spended time to diagnose panic disorder, Duration of treatment) were studied. Results : 1) QOL mean scores of a point of time 1,2 and 3 were 166.267±38.24, 94.367±34.00, 161.367±34.37, respectively. 2) The change of QOL scores in all five factors of KvSBQOL(factor1 Competence, factor2 Psychological well-being, factor3 Stability, factor4 Physical well-being, factor5 Activity)at each point was significant(P<.000). 3) The change of QOL mean scores(point 3 score-point 2 score) have significantly negative correlation with the change of score in anticipatory anxiety but not other predictors. Conclusions : Difference in QOL scores between a point of time 1 and 3 is 4.9, indicating that the psychiatric treatment is important in improvement of QOL, the anticipatory anxiety is an important predictor of QOL(P<.001). and it suggested that diminished anticipatory anxiety is very important to maintain of high QOL in patient with panic disorder.

태권도 차기기술의 관절과 분절 운동의 운동학적 정의

김승재,김로빈,신제민 한국운동역학회 1998 한국운동역학회지 Vol.8 No.2

The studies on Taekwondo kicking techniques have not been practical to apply to the teaching or coaching fields because they merely focused on the kicking leg and didn't define sufficiently overall motion patterns. The main reason for this is that there has been no useful method to describe complex Taekwondo kicking techniques such as Cardan angle which is effective to represent joint motion due to the production of three independent rotations about three independent axis. Therefore, the purpose of this study was to kinematically define the joint and segment motion by using Cardan angle during Dolgae-chagi(360 ˚ turning kick), Dwi-huryeochagi(backward thrashing kick) , and Dwi-chagi(back kick) in order to provide practical information for the Taekwondo teaching field. Six male elite Taekwondo players with the height of 177±5.6 cm and the weight 72.2±7.6 Kg were filmed using three-dimensional cinematography during Dolgae-chagi, Dwi-huryeochagi and Dwi-chagi. The joint and segment motion of the three Teakwondo kicking techniques was represented with Cardan angle calculated by the normal vector analysis. With Cardan angle the joint and segment motions of the three Taekwondo kicking techniques are defined as the following table.

Helicobacter pylori와 대장균의 Shuttle Vector 개발

조명제,이우곤,이상룡,김경희,안영숙,김성희,김현주,류복덕,최여정,윤영혜,백승철,전영석,이광호 경상대학교 유전공학연구소 1997 遺傳工學硏究所報 Vol.16 No.-

In this study, a vehicle vector using cryptic plasmids was constructed for gene transfer in Helicobacter pylori. pHP51(3.9 kb) and pHP489(1.2 kb) were selected for constructing vectors from cryptic plasmid of H. pylori isolates in Korea. The HindⅢ-digestedDNA fragment(1.2kb) of pHP489 and 1.6kb DNA fragment of pHP51 were ligated with a kanamycin resistance gene(aph3'-Ⅲ) from C. jejuni to produce the recombinant plasmids pHP489K and pHP51K, respectively. Transformation frequency of pHP51K by electroporation was low. But pHP489K could be effectively transformed into various H. pylori strains. In order to design an intermdiate vehicle vector for gene transfer into H. pylori, pBlueHP489K was prepared by recloning pHP489K DNA into pBluescript and pTZ19R vector. This vector permitted the DNA fragment containing pHP489 sequence, aph3'-Ⅲ, and cloned DNA to be cut and self-ligated in the SacⅠ site after cloning. ureA and ureB gene were inserted into pBlueHP489K, resulting in pBlueHP489K/AB. The DNA fragment containing pHP489, kanamycin resistance gene(aph3'-Ⅲ), and urease structural gene was cut away from pBlueHP489K/AB and self-ligated to generate pBlueHP489K/AB. pBlueHP489K/AB made urease-negative H. pylori strains restore their urease activity. By this experiment, pBlueHP489K was confirmed to be the vehicle system for transferring H. pylori genes.

고교 야구 선수들의 견관절 외회전 및 내회전근의 근력 및 그 특성

이제운,윤승호 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

The imbalance of rotator muscles of shoulder frequently causes shoulder injury in many baseball players. This study was intended to evaluate the strength characteristics of external and internal rotator muscles in high school baseball players. Isokinetic tests of external/internal rotators were performed using Cybex Ⅱ^+ Isokinetic dynamometer in nine pitchers, thirteen nonpitchers and twenty normal control subjects. And the flexibility of external rotator muscles of shoulder was evaluated by the hand-to-shoulder-blade Test. The results were as follows : 1) In pitchers, mean peak torque ratios of external/internal rotators were significantly high in nondominant side at 180 and 300 deg/sec, mean peak torque and mean peak torque body weight ratios of external rotators were significantly high in nondominant side at 180 deg/sec, 180 and 300 deg/sec respectively, mean peak torque of internal rotators were significantly high in dominant side at 300 deg/sec. 2) In nonpitchers, peak torque ratios of external/internal rotators were significantly high in nondo minant side at 180 deg/sec, but peak torque and peak torque body weight ratios of internal rotators were both significantly high in dominant side at 180 and 300 deg/sec. 3) In comparison between pitchers and nonpitchers, peak torque ratios of external/internal rotators in dominant side were significantly high in nonpitchers at 180 and 300 deg/sec, but there were no significant differences in nondominant side. 4) In flexibility tests of external rotators, pitchers showed statistically significant tightness in external rotators than nonpitchers and control group in dominant side, but there were no statistically significant differences in nondominant side. In conclusion, pitchers showed weakness and tightness in shoulder external rotators, which may lead to major shoulder injury. Therefore evaluation of muscle power and flexibility was thought to be one of the very useful screening tests for the prevention of shoulder injury.

Epstein-Barr 바이러스 형질전환법을 이용한 파상풍 톡소이드에 대한 사람 단세포군 항체의 생산

유승민,조정제,호순태,하윤문 大韓免疫學會 1993 大韓免疫學會誌 Vol.15 No.-

For production of tetanus toxoid(TT) specific human monoclonal antibodies, anti-TT antibody secreting peripheral B lymphocytes were separated by rosetting with TT-coated SRBC. And, B lymphoblastoid cell line(BLCL) was established by Epstein-Barr Virus(EBV) transformation methods. Stable BLCLs were established after three times of cloning by limiting dilution. To establish the maximal antibody producing condition, several environmental factors were tested. The optimal condition for maximum antibody prodiction was 4 day culture of 1 x 105cells/ml concentration in RPMI 1640 complete culture media supplemented with 20% fetal calf serum, and the maximum concentration of secreted antibody was about 900ng/ml. The antibody production of BLCL was decreased during long-term culture after establishment of cell line, but antibody production was maintained by repeated cloning by limiting dilution.

흉부외상 없이 발생한 흉부대동맥 절단증의 조기 진단 : 2례 보고 Two Cases Report

한승백,전영진,백광제,김준식,김정택,김광호,선경 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Aortic transection or interruption is a rare condition which developed after an acute deceleration injury. Its occurrence depends on the location and direction of the force applied and is usually from motor vehicle accident or falling down. The exact incidence of aortic transection in trauma is not known but, when develops, only about 10-15% of the victims can survive and be transported to the hospital. Even in the survivors, majority of them will be fatal within a few days if a prompt diagnosis and surgical treatments are not made. Aggressive diagnostic work-up is recommended for the patients with high suspicious index, which would salvage the victims with this fatal condition. We report the experience of two cases of aortic transection or interruption following motor vehicle accidents.

유치 매복에 관한 증례보고

이제호,이종갑,최병재,전승준 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.2

The term impaction is defined as a tooth has failed to erupt into normal position beyond the time usually expected for such appearance. Most of the cases of unerupted and impacted teeth reported in the literature are of permanent teeth. Impactions of mandibular primary second molars, however, are as numerous as all other primary impactions combined. Early detection of impaction is necessary during periodic oral examination and also radiographic examination and proper management is needed, because impaction of primary tooth may lead to obstruction of successive permanent tooth, space loss, and cystic change of tooth follicle. In these cases, 5 cases of primary teeth impaction are presented. Impaction teeth of each cases are maxillary primary incisor, maxillary and mandibular second primary molar, mandibular first primary molar. Following results were achieved by these cases; 1. In this cases, the cause of primary tooth impaction are abnormal eruption path, odontoma and fibrotic gingiva. 2. In this cases, impaction of primary tooth results in eruption problem of successive permanent tooth and failure of space maintenance. 3. Proper treatment plan should be established after through consideration of impacted tooth and it's relation with successive permanent tooth, and periodic examination and proper treatment about successive permanent tooth and eruptive condition is needed.

담배에 형질발현된 완두 rbcS GENE의 발현

박승희,우제창 木浦大學校 基礎科學硏究所 1995 基礎科學硏究誌 Vol.13 No.-

Using a binary vector system with pea rbcS gene and hygromycin phosphotransferase gene for selectable marker, tobacco plant was transformed by means of a leaf disc transformation method. After co-cultivation, bacterial cells were removed by cefotaxim treatment. Transformed shoots were developed from the co-cultivated leaf disc within 1 to 2 weeks in selection media supplemented with 25㎍/㎖ hygromycin and 50㎍/㎖ kanamycin. While normal plants could not grow in the medium with 25㎍/㎖ hygromycin the transformed plants could survive in the medium with 200㎍/㎖ hygromycin. It meant that resistant gene and rbcS gene was expressed in regenerated tobacco plants. Differential protein accumulation of RUBISCO small subunit was not detected by SDS-PAGE.