한국인의 항파상풍 항체 역가

구홍두,최옥경,장석준,정구영,이정운,김승호 대한응급의학회 1993 대한응급의학회지 Vol.4 No.2

Inspite of immunization, TETANUS remains a disease with a high morbidity and mortality rate. Tetanus has been still occurred more frequently in developing countries where immunization programs are inadequate. In Korea, there is a routine immunuzation schedule with diphtheria, pertussis, and tetanus(DPT) vaccines at 2,4,6 month after birth at 18 month. But further prophylactic programs are not exist. Moreover, we have usually used only passive immunization, tetanus antitoxin, as a prophylactic regimen for injured patients instead of guidelines of Center for Disease Control. The purpose of this study was to assess the baseline tetanus immunity state and to suggest the proper immunization schedule and adequate prophylactic guideline for injured patients in Korea. One hundred thirty one trauma patients from emergency department of Severance hospital from September to November of 1993 were included. Antietanus antibody titers of the patients were analyzed by ELISA assay. The mean antitetanus antibody titer was 0.728 ±0.236IU/mL. The titers were diminished rapidly with age. In pediatric group(age under 15), the mean titer was 3.251 ±0.426 IU/mL and in geriatric group(age over 64), the mean titer was 0.007 ±0.002 IU/mL which was below the minimal protective antibody titer(0.01 IU/mL). While all of the pediatric patients have protective antibody titer, only 69.2% of young adults(15-39, n=65), 56.7% of adults(40-64, n=30), and 57.2% of geriatrics(>65, n=14) have protective antibody titer. Our results suggest that tetanus prophylaxis is unnecessary in the age under 14. In other age groups, however, our data strongly support the need of prophyulaxis.

쌍동선의 운동 및 파랑하중 해석

구자삼,조효제,이승철 한국해양대학교 해양과학기술연구소 2000 硏究論文集 Vol.9 No.1

A three-dimensional linearised potential theory is presented for the prediction of motions and dynamic structural responses of twin-hull ships travelling with forward speed in regular waves. Comparisons between theoretical and experimental results are shown for the motion responses and lateral wave loads of an ASR(anti-submarine rescue) catamaran. In general, good agreement between theory and experiment is found except for some discrepancies that are believed to be caused by neglect of forward speed effects on free surface.

소비자신뢰지수의 소비지출 예측력 분석

김승년,구영완 한국은행 2005 經濟分析 Vol.11 No.1

본 논문은 국내의 경우 소비지출을 예측하는데 소비자신뢰지수가 유용한가를 통계적 기법을 통해 분석하고 있다. 삼성경제연구소와 한국은행의 소비자신뢰지수를 이용한 실증분석 결과, 국내 소비자신뢰지수의 예측력이 대체로 매우 낮지만 한국은행의 미래소비지수는 미래의 소비지출 예측에 있어 어느 정도 유용한 변수로 밝혀졌다. 따라서 본 논문이 시사하는 점은 국내의 미래소비지출 예측시 대표소비자신뢰지수 혹은 미래지수 등을 이용하기보다 한국은행 미래소비지수를 이용하는 것이 현시점에서 가장 유용한 선택인 것으로 보인다. 그러나 한국은행의 미래소비지수는 차선책임에 유의할 필요가 있다. 한국은행 미래소비지수가 다른 신뢰지수에 비해 상대적으로 우월하지만 발표시점이 삼성경제연구소지수에 비해 한달 반 가량 늦기 때문에 이 지수를 이용하기 위해서는 당해 분기말까지 기다려야 하는 등의 문제점이 있다. This paper examines the ability of consumer sentiment index in forecasting consumption expenditures in South Korea. The two most widely known measures of consumer sentiment in South Korea - from Samsung Economic Research Institute and the Bank of Korea - were used for empirical tests. Only the future consumption index released by Bank of Korea was found to have some predictive power in forecasting consumption growth. It needs to be recognized, however, that the predictive power of the future consumption index from the Bank of Korea is restrictive in that the formal announcement time of the index is one and half a month late compared to the index of Samsung Economic Research Institute.

사료제조공정에서 발생된 악취처리에 관한 연구

박영구,김승호,최선도,고재철 三陟大學校 2000 論文集 Vol.33 No.2

Methods for the treatment of foul odor was physical, chemical and biological. In this study, we utilized biofilter for the treatment of foul odor. Importance factors of a microbe is nutrients, temperature, moistrure and pH. As the results, it was found that matter of the odor was trimethylamine, removal rate(η(%)) fo (CH₃)N₃ appeared 19.7%∼96.5%(site-1), 20%∼95.5%(site-2) after treated to the biofilter, and tended to decrease from 7 months later by a biofilter compaction. Also size of the tree chip was 2cm, degree of the foul odor was degree of 3∼4, propriety temperature was 20∼40℃, the rate of contained moisture was 60∼70%, acidity was pH=8.

Mn₃O₄의 합성과 CO₂흡착에 관한 연구

김승호,박영구,고재철 三陟大學校 2000 論文集 Vol.33 No.2

In this study, we synthesized Mn₃O₄ by the different equivalent ratio, investigated XRD, SEM, TG-DTA, BET, and the amount of adsorption of carbon dioxide. As the results, we surveyed that XRD main peak was Mn₃O₄, some peak was MnO₂ and Mn??O??, SEM was globular-shape of the majority, some neele-shape, TG-DTA had weight-loss from 100℃ to 400℃ and endothermic reaction over 400℃, BET was 14.16∼29.63㎡/g and the amount of chemisorption of carbon dioxide was 2.885∼19.628cc/g. Optimal equivalent ratio was 1.00 to the physi-chemisorption of carbon dioxide.

산성강하물의 침착량과 동태 해명에 관한 연구 -춘천과 서울 강우의 화학조성 비교 : Comparison of Chemical Composition of Rain Water between Chunchon and Seoul

김만구,강미희,임양석,박기준,황훈,이보경,홍승희,이동수 江原大學校 附設 環境硏究所 1999 環境硏究 Vol.16 No.-

The rain water samples were collected at Chunchon and Seoul by using wet only automatic sampler from January 1996 through December 1997. The daily base rain water samples collected over than 95% rainy events during the whole period. The samples were measured both pH and conductivity, and were analysed major ionic components, SO₄^(2-), NO₃^(-), Cl^(-), NH₄^(+), Ca^(2+), Na^(+) and K ^(+), by ion chromatography. In 1996, about 77% sampled rain water showed below pH 5.6 and the 60% of rain water was lower than pH 5.0. The volume weighted average pH was 4.7 at all sites. In 1997, the volume weighted average pH was 4.6 and 4.9 at Seoul and Chunchon, respectively. Among the rain water samples, 87% and 55% of samples showed below than pH 5.6 and 5.0, respectively. The pH value of Chunchon was significantly (p<0.05) lower than Seoul at the rain samples for less than 20 ㎜ rainfall. However conductivity of the rain samples were 20.9 μS/㎝ for 1996 and 27.7 μS/㎝ for 1997 at Seoul, and 19.1 μS/㎝ for 1996 and 14.1 μS/㎝ for 1997 at Chunchon. H₂SO₄AND HNO₃CONTRIBUTED 65.9% and 29.6% of free acidity at Seoul, respectively. The ratio of [NO₃^(-)]/[nss-SO₄^(2-)] were 0.43 at Seoul and 0.51 at Chunchon for rain samples for less than 20 ㎜ rainfall. The annual wet deposition of Cl^(-), NO₃^(-), SO₄^(2-), H^(+), Na^(+), NH₄^(+), K ^(+), Mg^(2+) and Ca^(2+), respectively, 568.8 ㎏/㎢, 1489.3 ㎏/㎢, 3184.8 ㎏/㎢, 20.9 ㎏/㎢, 249.4 ㎏/㎢, 1091.2 ㎏/㎢, 189.8 ㎏/㎢, 90.2 ㎏/㎢, and 702.4 ㎏/㎢ at Seoul for 1996; 656.4 ㎏/㎢, 2029.7 ㎏/㎢, 3280.7 ㎏/㎢,27.2 ㎏/㎢, 229.4 ㎏/㎢, 1063.9 ㎏/㎢, 106.9 ㎏/㎢, 7802 ㎏/㎢, and 645.3 ㎏/㎢, at Seoul for 1997; 116.9 ㎏/㎢, 983.3 ㎏/㎢, 1797.0 ㎏/㎢, 21.4 ㎏/㎢, 83.2 ㎏/㎢, 648.1 ㎏/㎢, 78.0 ㎏/㎢, 22.2 ㎏/㎢ and 368.8 ㎏/㎢ at Chunchon for 1996; 100.2 ㎏/㎢, 1077.6 ㎏/㎢, 1754.0 ㎏/㎢, 13.4 ㎏/㎢, 146.0 ㎏/㎢, 602.3 ㎏/㎢, 88.8 ㎏/㎢, 16.2 ㎏/㎢ and 206.8 ㎏/㎢ at Chunchon for 1997.

Foix-Alajouanine 증후군 - 증례보고 -

조태구,어환,신형진,홍승철,김종수,박관,이정일,김종현 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.5

뇌졸중 위험인자를 가진 어지럼 환자에서의 확산강조 자기공명영상

강형구,윤유상,이진희,박인철,이경룡,정상원,구홍두,김승호 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: The management of vertiginous patients is a great challenge to emergency physicians. We evaluated the diagnostic value of a diffusion-weighted image(DWI) in differentiating central vertigo from the peripheral vertigo in patients who presented no neurological symptoms other than risk factors for stroke. Methods: From March 2000 to February 2001, we retrospectively analyzed the cases of 68 patients who visited the emergency department with symptoms of isolated vertigo and who had risk factors for stroke. DWIs, computed tomograms(CT), and medical records were reviewed, and the final diagnose, the DWIs and the CT readings, the risk factors for stroke, and the time it took waiting for a DWI or CT scan were analyzed. Results: Of the 68 patients, 21(30.8%) had central vertigo: 15 vertebrobasilar transient ischemic attacks(VB-TIA), 4 brain stem infarctions, 1 cerebellar infarction, and 1 cerebellopeduncular infarction. The DWI showed a 28.6% sensitivity, a 97.9% specificity, and an 85.7% positive predictive value in diagnosing central vertigo. It also had a 100% sensitivity in detecting infarctions. Conclusion: A DWI had a comparable sensitivity to MRI in detecting central vertigo and small, but potentially, lethal infarctions in our patient population. We recommend clinical application of DWI in the emergency department evaluation of isolated vertigo patients with risk factors for stroke.

제조합 대장균에서 과발현된 Citrobacter freundii KCTC2006 유래의 β-Tyrosinase를 이용한 3,4-Dihydroxyphenyl-L-alanine의 생산

이승구,노현수,홍승표,이규종,왕지원,태동년,엄기남,방상구,김영준,성문희 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.1

재조합 대장균에서 대량발현 시킨 Citrobacter freundii KCTC 2006 유래이 효소 β-tyrosinase를 이용하여 pyrocatechol, sodium pyruvate, ammonium acetate로부터 3,4-dihydroxy phenyl-L-alanine을 생산하기 위한 연구를 수행하였다. 이 효소반응에 적합한 온도 및 pH 조건은 각각 18℃와 8.5로 결정되었고, 반응액 중의 ammonium acetate와 sodium pyruvate의 농도는 각각 300 mM, 50 mM 이상으로 조절하는 것이 적합하였다. Pyrocatechol의 경우는 20 mM에서 가장 높은 반응성을 나타냈으나, 기질을 반복적으로 첨가하며 장시간 동안 효소반응을 수행하는 경우에는 pyrocatechol의 고갈을 피하기 위하여, 20 mM에서 50 mM 사이로 조절하였다. 한편, 반응액 중에 ethanol을 10% 첨가한 경우에는 반응속도가약 20% 증가하였다. 이상과 같은 효소반응특성에 기초하여 조제한 기질용액에 β-tyrosinase를 1 unit/㎖ 농도로 가하고, pyrocatechol과 pyruvate가 고갈되지 않도록 간헐적으로 첨가하면서 효소반응을 수행한 결과, 24시간 만에 85.2%의 수율로 31.6g/ℓ의 3,4-dihydroxyphenyl-L-alanine를 생산할 수 있었다. By using the β-tyrosinase of Citrobacter freundii KCTC2006, which was cloned and overexpressed in Escherichia coli, 3,4-dihydroxy phenyl-L-alanine (L-DOPA) was synthesized efficiently from pyrocatechol, sodium pyruvate, and ammonium acetate. Optimal temperature and pH for the reaction were determined to be about 18℃ and 8.5, respectively. The effects of substrate concentrations were also examined at different concentrations of ammonium acetate, sodium pyruvate, and pyrocatechol. Ammonium acetate and sodium pyruvate increased the reaction rate until the concentrations reached to 300 mM and 50 mM, respectively. Although pyrocatechol showed the optimal concentration at 20 mM, it was controlled between 20 mM and 50 mM to avoid the depletion of substrate during the enzymatic synthesis. Based on above results, a reaction medium for the production of L-DOPA was prepared and incubated with 1 unit/㎖ of β-tyrosinase. Pyrocatechol and sodium pyruvate was added to the reaction solution intermittently to avoid the substrate depletion during the enzymatic reaction. After 24 hour of reaction, 31.6 g/ℓ L-DOPA was accumulated in the reaction solution as soluble and precipitated ones and the conversion yield was about 85.2%.

지체장애자의 社會適應向上을 위한 身體運動效果에 관한 調査 硏究

金相九,金承喆,安義洙 成均館大學校 科學技術硏究所 1985 論文集 Vol.36 No.2

This study has the purpose to find effect of physical activity for improving social adaptation in a physically handicapped among middle and high school students in using of a questionaire to be consisted of 80 items over 10 factors. The total subjects of the study were 524 nonatheletes (middle school; 180, high school; 344), 123 atheletes (middle school; 60, high school; 63) from physically handicapped and 246 non-handicapped students. (middle school; 121, high school; 125) The results can be summarized as following presentation. 1, There was significant difference (P<.05) among non-handicapped, nonatheletes and atheletes of handicapped in the factor of social adaptation. The tendency which the score of handicapped(3.2318) was higher than that of non-handicapped(3.1651) is different from the consequences of pre-study. And it means significant effect of physical activity for improving social adaptation that the score of atheletes (3.2351) was more or less higher than that of nonatheletes (3.2310). 2. There was significant difference (P<.05) among 3 groups in the factor of morality and the score of atheletes (3.4587) was lower than that of non atheletes (3.5280) in handicapped students. It is considered that the consciousness, which atheletes has manipulated a various method in order to succeed in the contest of exercise and improve the records of theirs, induced dysfunction of physical activity in real life. 3. There was no significant difference (P>.05) in the factors of activity, emotional stability, sociability, dominance, impulsion, objectivity, restraint. 4. There ways significant difference (P<.01) among non-handicapped (3.5132), atheletes (3,4405), nonatheletes (3.3721) in the factor of physical fitness but no significant difference (P>.05) among 3 groups in the factor of exercise preference. It is considered there was no relation between self-confidence on physical fitness and the concern on physical activity. 5. There was no significant difference (P>.05) between atheletes and nonatheletes of handicapped students in the factor of social adaptation to the level of each grade (middle or high school)