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( Naganathan Selvakumar ),( Selvakumar Naganathan ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: Hepatic artery intimal dissection (HAD) followed by hepatic artery thrombosis (HAT) is serious complication of liver transplantation. There is paucity of information in literature on the management options for HAD encountered during surgery. In this study we describe a new classification and technique for the management of HAD during living donor liver transplant (LDLT). Methods: Based on the longitudinal extent of intimal dissection, HAD was classified into 4 types. Management was based on the availability of adequate length of hepatic artery and availability of alternate source of inflow. The dissected hepatic artery itself was used for arterial anastomosis in cases with preserved flow in the dissected artery and paucity of an alternative sources of arterial inflow. The technique of using the dissected artery is based on close approximation of tunica intima to media with the first two sutures of the arterial anastomosis. Patients with HAD were compared with those without HAD for evaluation of risk factors for intimal dissection. Results: 47 (2.4%) patients developed HAD during surgery. 22 (46.7%) patients had type II dissection for whom the other (right or the left) undissected hepatic artery was used for anastomosis. 20 (45%) patients were found to have major (type III or IV) dissection. The dissected artery was used for anastomosis in 9 of (45%) of these patients. Post-operative HAT developed in only one out of the 9 patients. Pre-existing portal vein thrombosis (PVT) and prior trans arterial embolization (TAE) were found to be major risk factors for development of intimal dissection. Conclusions: Classification
Selvakumar Sasirekha,Sankaranarayanan Swamynathan 한국통신학회 2017 Journal of communications and networks Vol.19 No.4
The sensor nodes have limited sensing, computation,communication capabilities and are mostly operated by batteriesin a harsh environment with non-replenishable power sources. These restrictions make the sensor network prone to failures becausemost of the energy is spent on data transmission, sensing, andcomputing. Many applications such as habitat monitoring, militarysurveillance and forest fire detection expect the sensor nodes to lastfor a long time because they operate human unattended. Therefore,the major challenges in designing a wireless sensor network (WSN)are energy conservation, reducing data transmission delay and improvingthe network lifetime. In this context, data aggregation is anintelligent technique used in WSN, wherein the data from disparatesources are accumulated at intermediate nodes, thereby reducingthe number of packets to be sent to the sink. Literature studyshows that various routing algorithms are used to perform dataaggregation based on the network topology. In order to provide animproved performance amongst the existing, a routing algorithmcalled cluster-chain mobile agent routing (CCMAR) is proposedin this work. It makes full use of the advantages of both low energyadaptive clustering hierarchy (LEACH) and power-efficientgathering in sensor information systems (PEGASIS). CCMAR dividesthe WSN into a few clusters and runs in two phases.The proposedsystem is simulated and evaluated for the performance metricssuch as energy consumption, transmission delay and networklifetime. The results demonstrate that the proposed CCMAR outperformsLEACH, PEGASIS and other similar routing algorithm,energy efficient cluster-chain based protocol.
Numerical Investigation of the Combustion Characteristics in a Can-Combustor with Swirl Effect
Selvakumar Kumaresh,Man Young Kim(김만영) 한국연소학회 2014 KOSCOSYMPOSIUM논문집 Vol.2014 No.5
Combustion phenomenon will be accomplished effectively by the development of low emission combustor. To study this flow, the chamber had to be designed to maintain the temperature of the combustion products below the maximum working temperature of turbine. This study is used to develop the effective combustion with low unburned combustion products by adopting the concept of high swirl flow and motility of holes in the secondary chamber. Thus the suppression of unburned gases is a meaningful objective for the development of high performance combustor.
Selvakumar T.,Nataraju B.,Chandrasekharan K.,Sharma S. D.,Balavenkatasubbaiah M.,Sudhakara Rao P.,Thiagarajan V.,Dandin S. B. Korean Society of Sericultural Science 2005 International Journal of Industrial Entomology Vol.11 No.1
While observing silkworm larval samples received from field, microsporidian spores formed within the haemocytes of silkworm haemolymph were observed. The spores of microsporidian sp. were purified and characterized for morphological characters viz., size, shape as well as serological affinity with different Nosema spp. (M$_{11}$ and M$_{12}$). The infectivity of the isolated spores to silkworm was also studied. The microsporidian sp. was found to be highly pathogenic to silkworm, B. mori. The isolated microsporidian sp. was designated as NIK-5hm, which formed ovocylindrical spore in the haemocytes of silkworm and differed in spore size (length, 4.55 $\mu$m & width, 2.10 $\mu$m) and shape from Nosema bombycis (NIK-ls), NIK-2r (Nosema sp. Mysore [3.6 & 2.8 $\mu$m]), NIK-3h (Nosema sp. M$_{11}$ [3.8 & 1.8 $\mu$m]), NIK-4m (Nosema sp. M$_{12}$ [5.0 & 2.1 $\mu$m]) and Lb$_{ms}$ (Nosema sp. in Lamerine breed of silkworm [4.36 & 2.14]). In immonological test (Latex agglutination test), the isolated microsporidian spores did not react with antibody sensitized latex particles of N. bombycis, M$_{11}$, M$_{12}$ and Lb$_{ms}$ and thus are different type of microsporidian sp., parasitic to silkworm, Bombyx mori L.
Selvakumar Edwardraja,Ganapathiraman Munussami,Amit Goyal,이선구 한국생물공학회 2016 Biotechnology and Bioprocess Engineering Vol.21 No.6
There is a considerable interest in the detection of GFP-like proteins due to their structural stability and functional usefulness. GFP-like proteins share highly conserved beta-barrel fold with 11 beta-strands. However, their low sequence identity hampers efficient identification of their homologous proteins from database. In this study, an attempt was made to generate a fingerprint for efficient detection of GFP-like proteins. Overlapped conserved residues (OCR)-based approach has been used to design a protein fingerprint based on sequentially and structurally conserved residues in secondary structures to detect homologous proteins very efficiently. Therefore, a fingerprint for GFP-like fold was designed using the OCR approach. However, its specificity was too low to be used for the identification of novel proteins. The conserved residues of loop regions were added and optimized to improve its specificity without losing its high sensitivity. The optimized fingerprint was employed to scan NR database. A total of 20 hypothetical proteins were detected, among which nine were validated as potential GFP-like homologs.