Could cluster of risk factors predict clinical outcome in patients with acute myocardial infarction?

( Sang Mi Park ),( Hong Nyun Kim ),( Se Yong Jang ),( Myung Hwan Bae ),( Dong Heon Yang ),( Hun Sik Park ),( Yongkeun Cho ),( Shung Chull Chae ),( Jang Hoon Lee ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1

Purpose: Conventional risk factors are differently contributed to short-term prognosis of acute myocardial infarction (AMI); hypertension and diabetes increase adverse outcome, whereas hyperlipidemia, smoking, and obesity paradoxically decrease adverse outcome of post-MI patients. The aim of this study is to assess whether cluster of conventional risk factors, PARADOCS (Pressure of ARtery Abnormality, Diabetes, Obesity, Cholesterol, Smoking) score, would improve the ability to predict major adverse cardiac events (MACEs) in patients with AMI. Methods: Between November 2005 and July 2011, 24,020 patients (17,232 men; mean age=63.0±12.8) with AMI were analyzed from Korean AMI registry. PARADOCS score was calculated as follows; [number of non-paradoxical risk factors (NRF) -number of paradoxical risk factors (PRF)]+3 in which non-paradoxical risk factors are hypertension and diabetes, and paradoxical risk factors are the rest. The 1-year MACEs were defined as death and non-fatal MI. Results: NRF including hypertension and diabetes were present in 49.6% and 27.0%, whereas PRF including hyperlipidemia, smoking, and obesity were present in 12.3%, 43.0%, and 34.6%, respectively. During the follow-up, 1,409 (5.9%) MACEs occurred. PARADOCS score was significantly higher in patients with 1-year MACEs (3.38±1.03 versus 2.81±1.08, p<0.001). In Cox proportional hazards model, PARADOCS score was an independent predictor of 1-year MACEs (hazards ratio 1.26, 95% confidence interval 1.18-1.34; p<0.001) after adjusting for confounding variables. Patients were categorized into 3 groups according to the PARADOCS score; PARADOCSLOW (0-1, n=2,446), PARADOCSMID (2-3, n=14,594), and PARADOCSHIGH (4-5, n= 6,980). Kaplan-Meier survival curve showed that there were significant differences in the 1-year MACEs among three groups including 3.5% in PARADOCSLOW, 8.5% in PARADOCSMID, and 16.4% in PARADOCSHIGH, respectively (long-rank p<0.001). Conclusions: In post-MI patients, conventional risk factors are differently associated with short-term prognosis, and score of these risk factors, PARADOCS score, can provide useful prognostic information to clinicians.

간호학생들의 전공선택동기와 전공만족도, 전문직업관

전은미, 강세원 배재대학교 자연과학연구소 2019 自然科學論文集 Vol.30 No.1

The purpose of this study was to investigate motivation for major selection, major satisfaction and professionalism among nursing students. Data collection was conducted at the two universities from August to September 2019 by convenience sampling. As a result, personal motivation in major selection was positively correlated with major satisfaction and professionalism (r=0.703, p<0.001; r=0.379, p<0.001). In addition, major satisfaction scores and professional occupation scores were higher in the group with high personal motivation(t=5.955, p<0.001; t=2.903, p=0.004). Motivation for major selection can affect major satisfaction and professionalism. Therefore, it is necessary for students before major selection to have sufficient opportunities to search for majors. 본 연구는 간호학생들의 전공선택동기와 전공만족도, 전문직관에 대해 알아보고자 조사되었다. 자료수집은 2019년 8월에서 9월까지 두 개 대학에서 편의표출로 시행되었다. 본 연구 결과, 전공선택동기에서 개인적 동기는 전공만족도와 전문직업관과 양의 상관관계를 보였다(r=0.703, p<0.001; r=0.379, p<0.001). 또한 개인적 동기가 높은 집단에서 전공만족도 점수와 전문직업관 점수가 높게 나타났다(t=5.955, p<0.001; t=2.903, p=0.004). 전공선택동기는 전공만족도와 전문직관에 영향을 미칠 수 있다. 따라서 전공 선택전 학생들이 충분한 전공탐색의 기회를 가지는 것이 필요하다.

간호학생의 4차 산업기술에 따른 간호직 고용 인식과 핵심역량 인식

전은미, 강세원 배재대학교 자연과학연구소 2018 自然科學論文集 Vol.29 No.1

본 연구는 간호학생들의 4차 산업기술에 따른 간호직 고용 인식과 핵심역량 인식을 파악하고자 하였다. 자료수집은 2018년 8월에서 10월까지 두 개 대학에서 편의표출로 시행되었다. 본 연구 결과 간호학생들의 4차 산업기술에 대한 이해도는 중간 이하로 나타났으며, 간호직 고용 대체 확률은 10-19% 응답비율이 가장 높았다. 간호학생들이 인지한 미래사회 변화에 필요한 중요 역량은 ‘종합적 사고력’이었다. 간호학생들의 변화하는 기술사회에 대처할 수 있는 역량을 개발하기 위해 교과-비교과 과정을 통한 다양한 방안의 모색이 필요하다. The purpose of this study was to identify the recognition of nursing employment and core competencies according to the fourth industrial technology of nursing students. Data collection was conducted at the two universities from August to October 2018. As a result, understanding of fourth industrial technology was below middle level. The probability of substituting nursing jobs was the highest in the 10-19%. The important competence required for the change of future society recognized was 'comprehensive thinking ability'. In order to develop competencies to cope with the changing technological society of nursing students, it is necessary to seek various ways through the curriculum and extra-curriculum.

신입간호학생들의 직업선호도와 간호직업에 대한 평가

전은미 , 강세원 배재대학교 자연과학연구소 2018 自然科學論文集 Vol.29 No.1

본 연구는 신입간호학생들의 직업선호도와 간호직업에 대한 평가를 알아보고자 조사되었다. 자료수집은 2018년 6월에서 10월까지 두 개 대학에서 편의표출로 시행되었다. 본 연구 결과, 간호학과 신입생들의 직업선호도 평가에서 ‘높은 임금’이 선호되었으며, 간호직업에 대한 평가에서는 ‘남을 도울 수 있는 직업’이 가장 높은 평가 점수를 보였다. 직업선호도와 간호직업 평가에서 모두 가장 낮은 점수를 보인 항목은 ‘창조하고 새로 만드는 것을 할 수 있는 직업’이었다. 간호학생과 학생들이 직업에 대한 이해를 충분히 할 수 있도록 다양한 탐색 방안을 마련하는 것이 필요하다 The purpose of this study was to investigate the occupational preference and evaluation of nursing job on new nursing students. Data collection was conducted at the two universities from June to October 2018 by convenience sampling. As a result, 'high wage' was preferred in the occupational preference. In the evaluation of nursing job, it was evaluated as 'job that can help others'. The lowest score item of both job preference and nursing job evaluation was 'job to create and to make new'. It is necessary to provide diverse approaches for nursing students to understand their profession.

마우스에서 조합시험법에 의한 고려홍삼의 생식발생독성 평가

김미라, 박동선, 장자영, 신선희, 이예은, 백인정, 연정민, 이세라 , 남상섭, 황방연, 노재섭, 김순선, 조대현, 남상윤, 이범준, 김윤배, 윤영원 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.1

본문참조

고감도 에어백용 실리콘 가속도센서의 설계

손미정,김경기,서희돈,최세곤 嶺南大學校 工業技術硏究所 1997 工業技術硏究所論文集 Vol.25 No.1

This paper presents the high sensitivity silicon piezoresitive accelerometer for possible use in an automotive airbag system. Two basic types of silicon piezoresitive accelerometers(bridge-type and cantilever-type)have some problems in the sensitivity and resonance frequency. The bridge-type has high resonance frequency and low sensitivity, but the cantilever-type has everse property. in order to improve the properties of the silicon piezoresistive accelerometer, we propose a new type of silicon accelerometer that have three beams. The proposed structure is that two beams are located at the each comer of the right side, and the other is at center of the left side. The optimized overallsize of the new type accelerometer is more smaller than two basic types of accelerometer. In the simulated reselts using analytical formelae and finite-element modeling(FEM), It's maximum stress is 26MPa and resonance frequency is 3250Hz for 50 G acceleration, respectively. The proposed structure is expected to be applied to much wider use automotive airbag application than the other structures.

카오스와 리아프노프 지수

김연미,유세라 弘益大學校 科學技術硏究所 1998 科學技術硏究論文集 Vol.9 No.1

In this paper, we try to approach chaos with numerical method. After investigating nonlinear dynamics (chaos) theory, we introduce Lyapunov expontent as chaos's index. To lood into the existence of chaos in a 2-dimensional difference equation, we compute Lyapunov exponent and examine various behaviors of solutions by bifurcation map.

수평 매복된 상악 중절치의 교정적 견인 : 증례 보고

김미니,김영재,김정욱,장기택,김종철,한세현,이상훈 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.4

본 증례는 수평 변위 매복과 치근 만곡을 가진 상악 중절치를 폐쇄 노출법을 이용한 교정적 견인을 시행하여 영구 전치의 기능과 심미성을 회복하였다. 상악 영구 전치가 수평으로 매복된 경우,가급적 조기에 발견하는 것이 중요하며, 촉진,시진,방사선 사진 등을 이용한 적절한 치료 계획의 수립이 필요하다. 상악 영구 전치의 매복이 조기에 적절히 치료되지 못하면 정중선의 변위,인접치의 이동에 의한 맹출 공간의 감소,치조골 높이의 차이 뿐만 아니라,이로 인한 심미적인 문제를 야기하여 소아 심리 발달에 해로운 영향을 줄 수 있기 때문이다. 매복치의 치료는 매복치의 형태,위치,상태에 따라 다양하나,주기적 관찰 방법,상부 연조직과 경조직을 단순히 제거하여 맹출을 유도하는 방법,외과적 노출 후 매복치를 교정적으로 견인하는 방법,치아 이식술,발치 등을 시행할 수 있다. 이중 이번 증례에서 시행한 매복치의 교정적 견인은 매복치의 치축이 정상 맹출로와 일치되지 않으며,주기적인 관찰 후 더 이상의 맹출이 기대되지 않을 때 시행하는 가장 일반적으로 적용되는 방법으로 매복의 심도,치아의 발육단계,만곡의 부위와 정도,수술방법과 견인방향 등을 고려하여 치료의 예후를 향상 시킬 수 있다. Maxillary central incisor impactions occur infrequently. Their origins include various local causes, such as odontoma, supernumerary teeth, space loss, and disturbances in the eruption path, also trauma and apical follicular cysts. Impacted teeth can cause serious dental and aesthetic difficulties as well as psychological problems especially in anterior regions. Although the impaction of maxillary incisor occurs less frequently than that of the maxillary canine. it is of concern to parents during the early mixed dentition stage because of the uneruption of the tooth. Forced eruption of impacted teeth should be considered in young patients because this technique can lead to suitable results from a periodontal, occlusal, and esthetic perspective at an earlier stage better than with other treatment options. This report presents the surgical and orthodontic treatment of cases with horizontally impacted and dilacerated maxillary central incisors. For each patient. we used the closed eruption method. placed an attachment on the impacted tooth on surgery, and fully closed the flap. Traction was applied immediately. The impacted tooth erupts through the healed tissue in a manner resembling normal eruption.

식품유해세균에 대한 식초의 항균효과

우승미,장세영,김옥미,윤광섭,정용진 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2004 한국식품저장유통학회지 Vol.11 No.1

본 연구에서는 시판되고 있는 식초를 이용하여 6종의 식품 유해세균에 대한 항균력을 비교하였다. 그 결과, 감식초와 현미식초는 합성식초에 비해 S. aureus, M. luteus, S. enteritidis 및 E. coli에서 항균 활성이 높게 나타났으며, 현미식초가 감식초에 비해 식품유해세균에 대한 항균활성이 비교적 더 높게 나타났다. 현미식초의 농도에 따른 항균활성을 조사한 결과 5종의 그람양성 세균 및 음성 세균 모두 10μm/mL 이상의 농도에서 생육이 거의 억제되었으나, V. parahaemolyticus는 15 μm/mL 농도에서 생육이 거의 정지되어, 현미식초는 식품 부패균과 대장균 생육억제에 우수한 것으로 나타났다. 식초처리에 의한 미생물의 형태 변화를 전자 현미경으로 관찰한 결과 S. aureus, E. coli 모두 세포가 팽윤되고 일부 세포벽이 완전히 파괴된 형태를 관찰할 수 있어 식초처리로 인해 세균의 생육이 억제되는 것을 알 수 있었다. We investigated antimicrobial effects of commercial vinegar on the harmful food-born organisms. As a result, antimicrobial effects of brown rice vinegar showed stronger than persimmon and artificial vinegar. In 10μL/mL concentration of brown rice vinegar was completely inhibited about 5 strains except for V. parahaemolyticus, it was inhibited 15 μL/mL concentration. Therefore vinegars were effective for inhibition acitivity against foodborne organisms. S. aureus and E. coli treated with 25μL/mL concentration brown rice vinegar was observed by scanning electron micrographs(SEM). The cells were expanded and a part of cell wall was completely destructed by brown rice vinegar.

GT rotary file을 이용한 근관성형법과 충전방법의 비교

강유미,진정희,유미경,이세준,이광원 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.5

The purpose of this study was to compare the shaping time of two shaping methods and the leakage of three different obturation techniques. Ninty three canaled human molar teeth were used. which were randomly divided into two groups of forty teeth each and ten control teeth. After working length determination. the one group was prepared crowndown technique using rotary root canal instruments of GT rotary files .12/20, .10/20, .08/20 and .06/20 taper(Maillefer Instrument SA. Switzerland). The other group was instrumented with Gates Gildden burs(#1, #2 and #3) to coronal preparation and GT rotary files .08/20 and .06/20 taper to apical preparation. Shaping time was measured. After root canals were instrumented, they were divided to three subgroups and obturated as follows: Subgroup 1, obturated with single cone method : Subgroup 2, obturated with lateral condensation : Subgroup 3, obturated with continuous wave technique. Three subgroups were obturated using non-standardized gutta-percha cone(Diadent, Korea, 06 or .08 taper) and AH-26(Dentsply DeTrey, Germany) as a root canal cement. Ten unobturated teeth served as positive and negative controls. After immersion in 2% methylene blue solution for 1 month, the teeth were washed during 24h. The teeth were determineralized in 10% nitric aciid and dehydrated by immersion in 80, 90 and 100% ethyl alcohol. The teeth were finally cleared and stored in 100% methylsalicylate, and apical dye penetration was evaluated under stereomicroscope(Leica M420, LC, U.S.A) at (×) 8.75 magnification. Liner measurement of dye penetration was assessed with the use of digitalized image analysing system (analySIS, GmbH, Germany), The data were analysed statistically using independent T-test and Two-way ANOVA and Tukey test. The result were as follows: 1. In canal prepared with GT^Trotary file, shaphing time taked more than the group of using Gates Gildden drill to coronal preparation without statistical significant (p>0.05). 2. The group of single cone obturation using canal preparation of GT^TM rotary files showed significantly more apical leakage than those of lateral condensation and continuous wave technique regardless of shaping method (p<0.05). 3. The group of single cone obturation using canal preparation of GT^TM rotary files and Gates Gildden drill showed significantly more apical leakage than those of continuous wave technique regardless of shaping method (p<0.05). 4. Regardless of shaping method. The group of continuous wave obturation showed less apical leakage than those of lateral condensation without statistical significance (p>0.05). 5. The group of single cone obturation using canal preparation of GT^TM rotary files and Gates Gildden drill showed more apical leakage than the group of lateral condensation using sane shaping method without statistical significance (p>0.05).