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Fuzzy SF : Towards the ultimate customised dictionary
Schryver, Gilles Maurice de,Prinsloo, Dj 연세대학교 언어정보개발원 2001 사전편찬학 연구 Vol.11 No.1
Fuzzy SF, a novel concept for an electronic-dictionary package, is presented. In Fuzzy SF, log-file based Artificial Intelligence components enable the implicit retrieval of personalised user feedback with which the package customises each user's own and unique dictionary. To that end, all the data in both the databases and the multimedia (sub)corpora are graded using Fuzzy Sets, so that the package only answers queries on the user's (current) level.
Local Immunoglobulin E in the Nasal Mucosa: Clinical Implications
Els De Schryver,Lien Devuyst,Lara Derycke,Melissa Dullaers,Thibaut Van Zele,Claus Bachert,Philippe Gevaert 대한천식알레르기학회 2015 Allergy, Asthma & Immunology Research Vol.7 No.4
Immunoglobulin E (IgE) can be highly elevated in the airway mucosa independently of IgE serum levels and atopic status. Mostly, systemic markers are assessed to investigate inflammation in airway disease for research or clinical practice. A more accurate but more cumbersome approach to determine inflammation at the target organ would be to evaluate markers locally. We review evidence for local production of IgE in allergic rhinitis (AR) and chronic rhinosinusitis with nasal polyps (CRSwNP). Diagnostic and therapeutic consequences in clinical practice are discussed. We describe that the airway mucosa has the intrinsic capability to produce IgE. Moreover, not only do IgE-positive B cells reside within the mucosa, but all tools are present locally for affinity maturation by somatic hypermutation (SHM), clonal expansion, and class switch recombination to IgE. Recognizing local IgE in the absence of systemic IgE has diagnostic and therapeutic consequences. Therefore, we emphasize the importance of local IgE in patients with a history of AR or CRSwNP.