마리화나 精神病 一例

陳聖太 大韓神經精神醫學會 1972 신경정신의학 Vol.11 No.3

The author reported a clinical case of marihuana induced psychosis following the general consideration about marihuana itself-canabis sativa. Hallucinogens such as LSD, mescline, psilocybin etc. have not been the problem socially as well as medically in Korea up to the present time except marihuana which seems to have recently been used by some Korean residing near the U.S. Army camp. It appears that marihuana is a comparatively mild intoxicant in ordinary preparation without causing physical dependence or tolerance. Upon reviewing literatures regarding marihuana psychosis, one can note two different opinions about marihuana psychosis in terms of it's causation. Some earlier investigators insisted that marihuana can induce psychosis directly, but most of others did not agree that marihuana can produce functional psychathology or psychosis but can mostly precipitate it in persons so predisposed. The patient presented in this paper is a 24 year old waitress who became psychotic after rather persitent use of marihuana of 6 weeks' duration(one to two cigarrete a day) to relieve feeling of depression with separation anxiety. She was found to have been hysterical and emotonally unstable person associated with borderline mental retardation (total IQ; 82) prior to her becoming psychotic. It is probable that psychosis in this case is due to her excessive marihuana smoking behavior as precitating factor on the top of the pre-existing personality disorder with mental subnormality as prediposition. In terms of treatment she was successfully managed with a protective and supportive millieu in conjunction with pharmacotherapy (chlorpomazine 200-600mg per day) in acute and subacute phase of her illness. Since the patient has had long-standing personality deficit and subnormal intelligence she will have to be treated with long term supportive psychotherapy with medication as neceassary.

胎敎에 關한 硏究

陳聖太 大韓神經精神醫學會 1981 신경정신의학 Vol.20 No.2

Taekyo (fetal education) is a kind of education given during the fetal life, i.e., the prenatal period and it has been told and transmitted from generation to generation in Oriental societies (Korea, China and Japan) since old times. The author gathered literatures on Taekyo extensively, dividing them into two categories, i.e., the general literatures and the Oriental medical literatures and reviewed the contents of them. Attempts to study on Taekyo from various points of view were made; the review of history on prenatal influences and/or “maternal impressions”with reference to Taekyo, the comparison of both categories of literatures, the relations between Taekyo and folklores (both German & Korean), the meaning and the validity of Taekyo viewed from modern Western medicines and also from the aspect of modern Western medicines and also from the aspect of modern Western psychiatry. It was revealed that the pregnant woman in Oriental societies has been expected to educate her own child in his prenatal or fetal life as a parental duty for him since the ancient times. Similarly, in the West, there are known descriptions about the prenatal influences and/or“maternal impressions”in Old Testament and the writings of Hypocrites and the beliefs on “maternal impressions”had been transmitted up to the end of the nineteenth century at which time the scientific researches on “maternal impressions" were begun. However, no systematic or organized descriptions like Taekyo were found in the Western literatures. Taekyo can be defined as an education given to the child during prenatal period through attentions and precautions of a pregnant woman to her own behaviour and attitude of mind aiming at good influences on her child subsequently. The contents of Taekyo are 1) The pregnant woman must observe her own behaviour and perceptions maintaining the right conduct and the right perception, 2) The pregnant woman must behave, speak and think with courtesy, 3) In her own attitude of mind, i.e., mental and emotional attitudes, the pregnant woman must make all effort to purify her mind, to put her mind at rest and to control her mind maintaining the harmony, 4) The pregnant woman must make all effort to have her child identify the man of maturity and ideal, 5) Though the pregnant woman is the main person who gives education to her child, all the relatives in the house including husband are bound to participate in Taekyo. It appears that the main theoretical background of Taekyo is in accordance with the principles of Oriental philosophy and Oriental medicines which are based on the harmony and parallelism of mind and body as well as the holistic and the comprehensive view on man. In addition, the expressions of shamanistic way of thinking and magics are also recognized. With reference to folklores (Korean and German) related to the birth it seems that both folklores are similar in contents to considerable extent and they showed more shamanistic natures than that of Taekyo. Since the outset of scientific researches on “maternal impressions”at the end of the nineteenth century the mechanism and the validity of “maternal impressions" seem to have gradually been verifiable and Taekyo can also be validated accordingly. It appears that the practicing Taekyo can serve the promotion of mental health, the prevention of certain psychiatric disorders and also it can play a role of directive psychotherapy if properly done.

놀이에 關한 諸學說

陳聖太 최신의학사 1980 最新醫學 Vol.23 No.2

小兒精神科外來에서의 臨床經驗 : 初診患者에 關한 臨床考察을 中心으로

陳聖太 최신의학사 1982 最新醫學 Vol.25 No.1

정신분열병 양성 및 음성증상과 혈소판 Monoamine Oxidase 활성도

윤성환,김영훈,진성태 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.1

The intention of this study to investigate the relationship between the activity of platelet MAO and positive and negative symptoms in the male chronic schizphrenics by DSM-III. The authors devided the male chronic schizophrenics into positive, mixed and negative subgroups by Andreasen & Olsen Criteria(1982), and also each patient was evaluated in relation with positive and negative symptom scales proposed by Lewin & Meltzer(1984). The authors assayed kinetic constants(Vmax and Km) for platelet MAO from 22 drug-free schizophrenics and 22 normal controls, radioenzymatically using 14C-benzylamine as a substrate. The results were as follows ; 1) Schizophrenic subjects had a lower mean Vmax Value(5.20±1.58 nmoles10(-6) platelets/hr) and Km value(38.92±19.28×10(-6)M) for poatelet MAO than normal controls(8.07±4.54, 49.56±18.48). Authough lower mean Vmax had a statistical significance, Km did not have. 2) In case of paranoid group(n = 6), there were no statistical differences in kinetic constants for platelet MAO compared with non-paranoid group(n = 16). 3) There were no significant differences in kinetic constants for platelet MAO between positive, mixed and negative symptom group. 4) The difference between kinetic constants for platelet MAO and positive symptom scale and negative symptom scale were not significant statistically. 5) Each scale item in the negative symptoms was not significantly different from platelet MAO activity. Finally, we confirmed that activity of platelet MAO was lowered in chronic schizophrenics, but we did not find any possible relationship between the negative symptom of schizophrenia and kinetic constants for platelet MAO.

급성동통 환자 치료에 있어서 Sirdalud^(�)의 임상적 연구

이광진,안상로,징영안 최신의학사 1990 最新醫學 Vol.33 No.2

壓縮性 粘土地盤의 支持力에 관한 연구

鄭成敎,權鎬眞 동아대학교 공과대학 부설 한국자원개발연구소 1986 硏究報告 Vol.10 No.1

Bearing capacity failure occurs usually as a shear failure of the soil supporting the footing. The three principal modes of shear failure under foundation has been described as general shear failure, local shear failure, and punching shear fuilure. Generally the failure mode depends on the relative compressibility of the soil, geometrical and loading conditions and in-situ condition. Strictly speaking, the ultimate bearing capacity equation can be applied to the incompressible soil or to the general shear failure mode. In pratice, however, soil is compressible. In this paper, the characteristics of bearing capacity, penetration depth and state of equilibrium is studied on the very compressible soil through model test. Results are as follows. 1) In soft clay layer which causes punching shear failure, it is inappropriate to predict the penetration depth or to compute the bearing capacity using the formula assumed general shear failure. 2) In case of the same distribution load, the bearing capacity factor(N_(c)) increases with the width of the footing for the same relative depth(D/B), with the decreasing of the water content, with the loading velocity. 3) In case that the relative depth(D/B) is less than 1~3, the skin friction and the soil weight over the footing base (γD) can be neglected. 4) In case the relative depth from the rigid base is less than 3~7, the equilibrium state is under the influence of the rigid base.

Neurospora crassa의 포자형성 주기에 미치는 빛파장과 중금속 이온의 영향 관계 조사

한상진 한국환경독성학회 1995 환경독성보건학회지 Vol.10 No.2

The most periodlengths(r) of conidiation of Neurospora were shortened in the medium with Li^(+), Rb^(+), and Cs^(+) under the blue or green light. The higher the concentration of the heavy metal elements are, the shorter the circadian lengths are. The largest differences between the maxima- and minima circadian lengths showed in the medium with LiCl, RbCl, and CsCI under the blue lights at 150 Lux, while the little differences of circadian lengths presented in 1 mM heavy metal elements at the 270 Lux blue light. Li^(+) under the blue light effected extremely much and in the order of Rb^(+) and Cs^(+) on the conidiation of Neurospora. Under the green lights at 270 Lux, the smallest changes of the circadian lengths are resulted in the medium with heavy metal elements. The other way at the green light 150Lux, the conidiation is stimulated by ImM LiCI or RbCI for the average 0.71h and 0.29h longer than the periodlength of control 28.34h. The medium with Li^(+) under the green light has less effect on the conidiation rhythm of Neurospora than with Rb^(+) or Cs^(+).

인위적인 계절적 광주기에서 쥐에 나타나는 멜라토닌 분비양상과 정소크기변화 조사

한상진 한국환경독성학회 2003 환경독성보건학회지 Vol.18 No.1

Plasma melatonin in the seasonal light-period is circadian rhythmically secreted. Maximal secretion showed at 14 o'clock in summer- and winter-like period, but minimal secretion showed at 5 o'clock in summer-like period and at 8 in winter-like period. These times of minimal secretions were at the beginning of light period. Plasma melatonin in the light period is secreted 62.5% more than in the dark period in summer-like period and 45.9% more in winter-like period. Total plasma melatonin in winter-like period is secreted 56.5% more than in summer-like period. The weights of testis (-20.8%) and body (-7.1%) were reduced in the winter-like period. By the increase of plasma melatonin in mice, body- and testis-weights are decreased, on the contrary by the decrease of plasma melatonin in mice, body and testis weights arc increased. In view of the results so far achieved melatonin changes on the body weight and reproductive organ in mice. It is presumed that melatonin effects on the metabolism and sex hormone.

방사선 물질 Li^+, Rb^+, Cs^+이 Neurospora crassa의 성장 일주기에 미치는 영향

한상진 한국환경독성학회 1993 환경독성보건학회지 Vol.8 No.1

Radioactive elements Li^(+), Rb^(+) and Cs^(+) effect the period shortening in proportion to the higher concentration on the growth of Neurospora crassa. 1 mM LiCI presented the result of the period length 0.52 h shorter than average circadian rhythm 21.66 h. 1 mM RbCI reduced the period length 1.13 h than control period 21.89 h and 1 mM CsCI reduced 2.12 h than control period 21.89 h. In the equal concentration Cs^(+) had an extreme effect. Fatal doses of Li^(+), Rb^(+) and C^(+)+ are 20 mM, 30 mM and 20 mM. In the fatal concentration Neurospora didn't develop more after 7 days and the formation of spores were not given in regular order. Circadian length of Neurospora decreased generally at the last cycle of the growth.