忠州市 主幹線 道路邊 建築外部色彩에 關한 硏究

崔生吉,孫泰鎭,柳顯紀,辛同寅,梁富弘,尹勝照,朴碩鉉 忠州大學校 1998 한국교통대학교 논문집 Vol.33 No.2

In order to understand the influence of colours on the urban design of a city, a portion of the central Chung-Ju was chosen as the study area, and three cases were researched as colours. These surveyed colours are analysed in their hue, value and chroma. It was necessary to determine the colours of 272 buildings exterior in all in order formulate the findings presented in this study. The result of this study can be briefly summerised as the following ; 1) The trends in the use of colour turn out like this ; 55.3% of the building were Y(yellow), YR(yellow-green), R(red) Family in Hue, abour 33.9% of them were within 8.0-8.9 and 26.6% were within 7.0-7.9 on the value scale, and about 48.5% of them were within 1.0-1.9, 2.0-2.9 and 3.0-3.9 on the chroma scale. 1) For case 1 on the exterior colours of buildings, about 57.8% were Y and YR family in Hue, about 53.7% were 8.0-8.9 and 7.0-7.9 in Value, and about 49.6% of them were within 1.0-3.9 in chroma. 2) For case 2 on the exterior colours of buildings, about 52.4% were Y and R family in Hue, about 65.1% were 7.0-8.9 in Value, and about 46% were 1.0-2.9 in Chroma. 3) For case 3 on the exterior colours of buildings, about 55.7% were Y and YR Family in Hue, about 72.1% were 7.0-8.9 in Value, and about 31.1% were 2.0-2.9 in Chroma. In summary, the colours of the building surveyed in central Chung-Ju can be characerized as Y, YR, R, N family in Hue, 7.0-7.9, 8.0-8.9 in Value registered in 1.0-1.9, 2.0-2.9, 3.0-3.9 in Chroma. The observed exterior colours show a tendency toward Yellow in Hue, High in Value and low in Chroma. Generally, the majority of the colours is light rather than strong in tone.

<i>In vitro</i> and <i>in vivo</i> evaluation of a novel polymer-free everolimus-eluting stent by nitrogen-doped titanium dioxide film deposition

Park, Dae Sung,Bae, In-Ho,Jeong, Myung Ho,Lim, Kyung Seob,Sim, Doo Sun,Hong, Young Joon,Lee, So-Youn,Jang, Eun Jae,Shim, Jae-Won,Park, Jun-Kyu,Lim, Han Chul,Kim, Han Byul Elsevier 2018 Materials Science and Engineering C Vol.91 No.-

<P><B>Abstract</B></P> <P>Inflammation and thrombosis are linked to the use of polymer-based drug-eluting stents (DES). The aim of this study was to develop a polymer-free everolimus (EVL)-eluting stent using nitrogen-doped titanium dioxide (N-TiO<SUB>2</SUB>) and verify its efficacy by <I>in vitro</I> and <I>in vivo</I> assessment in a porcine coronary model. Various analytical approaches such as scanning electron microscopy and atomic force microscopy, electron spectroscopy, Fourier transform infrared spectrometry and contact angle measurement were employed for the characterization. As a part of biocompatibility assessment, platelet adhesion and smooth muscle cell (SMC) proliferation were examined. Bare metal stent (BMS), N-TiO<SUB>2</SUB> stent, everolimus-eluting N-TiO<SUB>2</SUB> (N-TiO<SUB>2</SUB>-EVL) stent, and commercialized EVL-eluting stent (EES) were randomly placed in forty coronary arteries in twenty pigs. After four weeks of implantation, the stents were subjected to histological and quantitative analysis. The N-TiO<SUB>2</SUB> film used in this study was well coated without any cracks or peeling. Surface hydrophilicity (88.8% of angle decrement) could be associated with the decrease in surface roughness post N-TiO<SUB>2</SUB> deposition (37.0%). The platelet adhesion on the N-TiO<SUB>2</SUB> surfaces was less than that on the BMS surface. The proliferation of SMC was suppressed in the N-TiO<SUB>2</SUB>-EVL group (30.2%) but not in the BMS group. In the animal study, the percent area restenosis was significantly decreased in the N-TiO<SUB>2</SUB>-EVL group compared to that in the BMS group. The results (BMS; 47.0 ± 11.00%, N-TiO<SUB>2</SUB>-EVL; 31.7 ± 10.50%, and EES; 29.1 ± 11.21%, <I>n</I> = 10, <I>p</I> < 0.05) were almost at par with those of the commercialized EVL-eluting stent. The introduction of N-TiO<SUB>2</SUB> deposition during fabrication of polymer-free DES may be an efficient accessorial process for preventing in-stent restenosis and thrombosis.</P> <P><B>Highlights</B></P> <P> <UL> <LI> N-TiO<SUB>2</SUB> surfaces can help to reduce the platelet adhesion. </LI> <LI> In porcine model, N-TiO<SUB>2</SUB> everolimus decreased in-stent restenosis and fibrin deposition. </LI> </UL> </P>

In-line 마그네트론 스퍼터 장치를 사용하여 산소 분위기에서 제작한 Ag 박막의 특성

구대영,김원목,조상무,황만수,이인규,정병기,이택성,이경석,조성훈,Ku, Dae-Young,Kim, Won-Mok,Cho, Sang-Moo,Hwang, Man-Soo,Lee, In-Kyu,Cheong, Byung-Ki,Lee, Taek-Sung,Lee, Kyeong-Seok,Cho, Sung-Hun 한국재료학회 2002 한국재료학회지 Vol.12 No.8

A study was made to examine the electrical, compositional, structural and morphological properties of Ag thin films deposited by DC magnetron sputtering in $O_2$ atmosphere with deposition temperature from room temperature to 15$0^{\circ}C$ using in-line sputter system. The Ag films deposited at temperature above $100^{\circ}C$ in oxygen atmosphere gave a similar specific resistivity to and even lower oxygen content than those deposited using pure Ar sputter gas The Ag films deposited with pure Ar gas was mainly composed of crystallites with [111] preferred orientation, while, for those deposited in oxygen atmosphere, more than 50% of the volume was composed of crystallites with [100] orientation. The difference in the micro structure did not cause any difference in the specific resistivity of Ag films. The results showed that the transparent conducting oxide films and the Ag films could be processed sequentially in the same deposition chamber with careful control of deposition temperature, which might result in a cost reduction for constructing the large scale in-line deposition system.

소아의 연령별 Propionibacterium acnes에 대한 균체응집항체 및 동종혈구응집항체간의 비교연구

정화영,정상인,최철순,양용태 중앙대학교 의과대학 의과학연구소 1984 中央醫大誌 Vol.9 No.3

In general, the concentration of maternal IgG globulin in serum of the neonates falls rapidly within the first few months after birth and the production of IgM globulin develops in the maturing infants during the course of exposure to various antigens in the environment. The development of natural antibodies, ie., isohemagglutinins, IgM class, to ABO blood group substances and agglutinins, Ig class, to normal flora, in the early stage of life is important since not only they may act as bactericidal substances in nonspecific manners, but also could be immunological barometers on the normal function of humoral immune system. The high concentration of isohemagglutinins to human A or B blood group antigens and agglutinating antibodies to some of normal flora such as Propionibacterium acnes or Staphylococcus aureus were observed in normal human sera. It has been known that the serum concentration of IgM globulin usually reached adult levels by one year of age, while that of IgG globulins by five to six years of age. However, the levels of isohemagglutinins to A and B group substances and agglutinating to Propionibacterium acnes in children's sera and the ages in which the concentrations of their antibodies reached to abult levels are not clarified. In this study, the concentrations of isohemagglutinins to A and B blood group antigens and agglutinating antibodies to P.acnes serotype Ⅰ and serotype Ⅱ in the sera of 163 normal children, ranged from 0 day to 15 years of age, were measured by means of microtitration technique. The results obtained are as follows: 1. In the sera of 163 children under 15 years of age, there observed no significant difference in the titers of agglutinating antibodies to P. acnes serotype Ⅰ andⅡ. 2. Of 75 sera of children under one year of age, the numbers of sera in which agglutinating antibodies were not detectable or less than 1:4 to P. acnes serotype Ⅰ were 67(89.6%) and to serotype Ⅱ 53(70.7%), respectively. 3. Agglutinating antibody to P. acnes serotype Ⅰ in the children's sera reached adult levels by 7 years of age, but 100 percentages of antibody detection was observed only in the age group of 15 years old, whereas the adult levels of isohemagglutinins to A and B blood group antigens were observed in the age group of 6 months old. 4. No correlation were observed in normal children's sera between agglutinating antibody titre to P. acnes serotype Ⅰ and isohemagglutinin titre. These results indicated that the isohemagglutinins to ABO blood substances appeared in the earlier stage of life than did agglutinating antibodies to P. acnes.

이종 면역글로불린인 Artroglobina^(�)에 의한 슬관절의 골성관절염치료

문명상,이인주 최신의학사 1982 最新醫學 Vol.25 No.10

韓國에 있어서 肝吸蟲症 分布에 관한 疫學的 硏究

宋寅喆,李駿商,林漢鐘 고려대학교 의과대학 1983 고려대 의대 잡지 Vol.20 No.1

Korea, a total number of 19,758 stool specimens were collected from the inhabitants who lived in the basins of main 6 rivers, i.e. the Han River, the Gum River, the Nakdong River, the Mangyong River, the Yongsan River and the Seomjin River. The specimens were examined both by cellophane thick smear method and Stoll's egg counting technique during the period from March 1973 to October 1982. The distribution and infection rates were compared in those of river and non-river sides, and the epidemiological statrs was analysed statistically by the regression equations and catalytic curves with the results obtained from two endemic areas. The results are as follows: 1. High egg positive rates were revealed among the inhabitants in the areas of all above river basins, whereas low egg positive rates were obtained among the inhabitants in the areas apart from the riversides. However, in some areas which are not directly connected with the rivers, relatively high rates of Clonorchis infection were also observed. 2. The infection rates of Clonorchis sinensis by sex age were shown significantly different among the population in the most of these studied areas. The rates for males were significantly higher than that for females, and the rates were increased by the higher age groups up to 40 to 59 years old. However in the high endemic areas such as Kimhae the infection rates of both sexes were almost parallel and practically similar high rates revealed in all age groups for 20 to 60 years old. 3. The mean E.P.G. count of Clonorchis infection in the surveyed areas was found higher in the areas which shown as higher infection rates. The degree of the intensity of Clonorchis infection by E,P.G. counts was evenly distributed to heavy and very heavy infections as well light and moderate infections in the areas showed high infection rates. 4. The intensity of endemicity in all surveyed areas was compared with the regression equations calculated with the cumulative percentages of E.P.G. counts. 5. For the quantitative analysis of epidemiology of clonorchiasis in Kimhae and Pyongtrek areas, special type of simple catalytic model was applied to the age prevalence rates revealed through stool examination for Clonorchis eggs and intradermal test for the detection of positive reactors. 6. It was suggested that the two-stage catalytic was well fitted to the prevalince rates by sex and age in the egg positive cases in Kimhae and Pyongtaek areas, and the calculation lead to the equation y=1.042(e-^(0.003t)-e^(-0.074t), a=0.074〉b=0.003 in Kimhae area, and y=1.412(e^(-0.024t)-e^(-0.041t), a=0.024〈b=0.041 in Pyongtaed area. 7. In the high endemic area such as Kimhae, the tendency of familial aggregation was not recognized by statistical analysis. In this area, the mean E.P.C. obtained from same persons in 1973 were compared and descussed statistically.

만성육아 종성염증에서의 T-cell 그리고 B-cell의 분포에 관한 연구

장인성,양승하,강상균 순천향대학교 1994 논문집 Vol.17 No.2

Tuberculosis, leprosy, foreign body reaction, parasite, and fungal infection are chronic granulomatous inflammation forming granuloma within lesion. There are much studies for the mechanism of cell mediated immume reaction in tuberculosis and leprosy, but the study using immune peroxidase stain in paraffin embedded tissue is rare. This study was carried out to observe the distribution of T cell and B cell in chronic granulomatious inflammation, such as tuberculosis 21 cases, leprosy 9 cases, cysticercosis 7 cases, and foreign body reaction 8 cases. Fourthy five cases of above diseases obtained by excisional biposy were processed for immune enzyme histologic stain by Avidin-Biotin complex method using MT1 and MB2. The results obtained are following as : 1. Tuberculosis showed positive reaction of MT1 in all within and outer granuloma among 21 cases, and MB2 in 2 cases and 14 cases respectively. 2. In 9 cases of leprosy lepromatous type showed positive reaction of MT1 in all 5 cases and MB2 in each 2 cases within and outer granuloma, tuberculoid and borderline types showed posittive reaction of MT1 and MB2 in all 2 cases respectively. 3. Positive reaction of MT1 in 7 cases of cysticercosis, revealed 6 cases within granuloma and all cases outer one, MB2 in 5 cases and 6 cases respectively. 4. Positive reaction of MT1 in 8 cases of foreign body reaction disclose 5 cases within granuloma and 7 cases outer one, and MB2 in 3 cases and 4 cases respectively. The above results showed T cell is related to main immune protective mechanism in granulomatous inflammation, and B cell reveal only weak reaction.

게오르그 뷔히너의 『당통의 죽음』에 나타난 內的 공간

곽인상 조선대학교 외국문화연구소 1997 外國文化硏究 Vol.20 No.1

Uns liegen derzeit unza¨hlig verschiedence Forschungsrichtungen in G. Bu¨chners Werken vor, als daB man in einer Flut des sogenannten Methoden bzw. Ansichtspluralismus ertrinken ko¨nnte. Dies hat einerseits mit der Offenheit der Werke von Bu¨chnner zu tun und ha¨ngt andererseits um mit Gadamer zu sprechen mit der "Geschichtlichkeit des Verstehens" zusammen. Dieser Zustand fu¨hrt uns zwangsla¨ufihg zum Nachdenken, ob man bis jetzt auf das Erkenntnismonopol besteht auch in bezug auf die Forschung der Bu¨chners Werke. So versucht die vorliegende Arbeit die Bedeutung des Innen-Raums bei Georg Bu¨chner und die Aspekte ihrer a¨sthetischen Konstellation in den Werken des Dichters zu kla¨ren. Die Studie u¨ber das Innen-Raum beim 「Dantons Tod」 spielt fu¨r die Interpretierung des Werkes wichtige Rolle, weil Danton in dem Innen-Raum sein Privatleben fu¨hrt. Ein Salon, ein Zimmer und Conciergerie geho¨ren dem Innen-Raum. Der Salon stellt die Autonomie der Szene dar Szene dar, obwohl er im Drama nur einmal auffritt. In dem Salon Zeigt Danton seine Innerlichkeit, in der Einsamkeit, Langweile, GenuB und 「Nicht-handeln」 sichbar werden. In dem Salon Zeight Danton seine Innerlichkeit, in der Einsamkeit, Langweile, GenuB und 「Nicht-handeln」 sichbar werden. Dieser Raum stellt den Sozial-Raum (eine Gasse I/2) gegenu¨ber, Es ist ein Grundregel der Kontrast, in der weitra¨umige Szenen mit engra¨umigen wechseln ; Pathetische Szenen mit desillusionierenden und umgekehrt. Die Atmospha¨re in dem Salon ist ganz anders in der Gasse. In dem Salon wird Damen. Karten, Kartenspiel, Schemel und gebildete Rede gezeight, die die der Gasse Gegenteil macht. Der Raum, ein Zimmer ist a¨hnlich wie der Salon, aber tritt sehr ha¨ufig (9 Szene) als der Salon auf. Auf der anderen Seite bedeutet das Zimmer Dantons Leben. Conciergerien sind noch begrenzter Ra¨ume als "Zimmer Dantons Leben. Conciergerien sind noch begrenzter Ra¨ume als "Zimmer" in seinem Leben. Das hat Zweideutigkeit zwischen Leben und Tod, vergleicht die Haltestelle zum Revolutionsplatz. Danton spielt seine Rolle in dem Innen-Raum, in den er seine Innerliche darstellt. Bu¨chner hat damit ein gedankenvolles und spannendes Drama geschafft, daB der Innenraum den Sozialraum und Naturraum gegenu¨berstellt. Also ko¨nnen wir das Drams 「Dantons Tod」 durch das Studium des Innenraums in dem Werk noch besser, tiefer interpretieren und verstehen.

運動의 危險性

朴鱗基,白永守,鄭泰相 忠南大學校體育科學硏究所 1993 體育科學硏究誌 Vol.11 No.1

The purpose of this study was to introduce the risk of exercise to exersize testing or participation. The real and theoretical benefits of regular exercise have promoted this activity not only in healthy individuals. but also in cardiac patients. Exercise is assuming an increasingly important role in preventive medicine and cardiac rehabilitation. Apart from favorable effects on plasma lipids, there is often the experience of even greater psychological benefits, that is, improved in mood, reduced nxiety, and sense of well-being. A through medical evaluation is recommended before starting an exercise program for all individuals with known cardiovascular, pulmonary or metabolic disease. Individuals of any age considered at higher risk by the presence of diabetes, hypertension, family history of coronary disease, elevated cholesterol, or smoking may benefit from the screening exercise test before engaging in competitive or recreational sports. Sudden death in sport is a recently recongnized phenomenon for which little scientific information exists. Most previous investigation on sudden death in sport has concentrated on running, track and field sports. Death, directly related to sporting activities is rate. The total risk is low, but the relative risk is increased during vigorous exercise. Risk increases with age and with the intensity of exercise. The basis of clinical studies and our personal experience, most deaths during exercise in the adult population are probably preventable because they occur in individuals exercising under one or more of the following circumstances: no medical clearance, no supervison, the limits of the exercise prescription were exceed, the symptoms during exercise were disregarded. Orthopedic injuries appear to increase exponentially with jog-run types of activities in association with increased the total volume of work done in the program, such as, structural abnomalities, sudden large increases in training, running form, streching habits, warm-up, and cool-down may constitude risk factors. With high risk individuals, a physician should be present during exercise intensity, and energy equipment and qualified personnel should be avaiable for exercise testing of all patients in order to provide life saving emergency are, In addition to significant clinical signs and symptoms.

한국인 알코올 의존 환자에서 알코올 대사 효소 유전자형 빈도의 남녀 차이

김성곤,김철민,이덕기,황인복,이현숙,김성연,전은숙,송영상,박제민,최병무,김명정 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2

Objectives : There are a number of preceding epidemiological studies reporting gender differences in the genetic etiology of alcohol dependence. The author investigated gender difference in the frequencies of ADH2 and ALDH2 genoypes between the patients with alcohol dependence and normal control. Methods : The subjects were 141 alcohol dependent patients (104 males, 37 females) and 138 normal control (79 males, 59 females). The frequencies of 1/1 and 1/2+2/2 (2+ afterward) genotypes for ADH2 and ALDH2 were investigated in male and female between alcohol dependence and normal control group. DNA was extracted from WBC in peripheral venous blood and PCR-RFLP method was used out for genotyping. Results : First, the frequency of ADH2 1/1 genotype was significantly higher in alcohol dependent patients than normal control in both genders. Second, while there was no gender difference in the frequency of ADH2 1/1 genotype in normal controls, in the patient group however, the frequency was significantly higher in females than males. Third, in male subjects with alcohol dependence, the frequency of ALDH2 1/1 genotype was significantly higher than in male normal control subjects. On the other hand, in female subjects with alcohol dependence, the frequency of ALDH2 2+ genotype was significantly higher than in female normal control subjects. Conclusion : These results suggest that while the risk of alcohol dependence is predominantly affected by ALDH2 1/1 geno-type in male, the female ADH2 1/1 genotype is mainly associated with the risk of alcohol dependence. This means that there are gender differences in the genetic etiology of alcohol dependence.